- Base-Breaking Character: Lollipup is either lovable sweetheart, or an obnoxious buffoon, depending on who you ask.
- Fridge Brilliance: Lollipup is shown occasionally speaking German. This is because the poodle breed actually originated in Germany.
- LGBT Fanbase: The comic has an LGBT following, due to many of the characters being openly LGBT- Liz and Lollipup are a lesbian couple, and Lollipup is a trans girl.
- Jerkass Woobie: Lemonhead is irritable, sarcastic, and quick to insults. However, her backstory sheds a bit of light on her sour disposition- before the events of the comics, she was attacked by a dog, which bit off her ear. She's shown to still have nightmares about this.
- Moral Event Horizon: Lollipup's abusive owner, who is occasionally alluded to, crossed it before the events of the main comic.
- Nightmare Fuel: Any time Lemonhead or Lollipup's backstories are referenced, things typically go downhill fast.
- Lemonhead accidentally chops off her hand while making soup. Good thing she can grow it back.
- Lemonhead removes her own head to make lemonade.
- Liz, like real lizards, can remove her tail and grow it back. She takes advantage of this to scare Lollipup on one occasion.
- In 'Liz and Lollipup's Green Christmas,' we're shown a brief flashback of Lollipup's owner about to strike Lollipup with a rolled-up newspaper.
- Tastes Like Diabetes: The comics can be a little too saccharine and sweet at times.
- Viewer Gender Confusion: Lemonhead is frequently mistaken for a boy by new readers.
YMMV / Lemonhead And Lollipup