Lemonhead and Lollipup
- Ambiguous Disorder: She seems to display some classical signs of depression and/or PTSD, if the comics about her backstory are any indication.
- Cats Are Mean : Downplayed- she's rude and sarcastic, but has a moral compass and is overall a Good Is Not Nice type.
- Cats Are Snarkers: Perpetually sarcastic.
- Cool Big Sis: Lollipup seems to think of Lemonhead this way.
- Dark and Troubled Past: At some point before the main comics, she was attacked by a dog, which bit off her ear.
- Fat Cat: A rotund cat.
- Healing Factor: She can recover from many injuries, due to being part plant. Oddly enough, this is averted with her ear injury.
- Jerk with a Heart of Gold: Quick to insults and ill-tempered, but will comfort Lollipup if she's upset, hurt, or sick.
- Odd Couple: With Lollipup.
- Planimal: Half-lemon and half-cat.
- Reasonable Authority Figure: Tends to play this role when dealing with Lollipup and Liz. In the wedding comic, she objects to Lollipup and Liz getting married, simply on the grounds that they're too young and impulsive; though she's willing to change her mind when she hears their side of it.
- Tertiary Sexual Characteristics: Averted- she's not drawn with accessories or eyelashes, and has thick eyebrows.
- Visual Pun: She's a sourpuss.
- Adorkable: She's a sweet, earnest goofball.
- Ambiguous Disorder: She's socially awkward, prone to accidentally getting on other people's nerves, and is prone to social faux pas. According to the author, Lollipup is on the autism spectrum.
- Big, Friendly Dog: A tall, lanky standard poodle with a sweet personality.
- The Ditz: While not exactly stupid, she is prone to clumsiness, immaturity, and obliviousness.
- Drama Queen: It doesn't take much to make her cry. Just look at her reaction when she accidentally drops a donut on the ground.
- Dreadful Musician: She loves to sing and play the ukulele; unfortunately, she's not very good at either.
- Innocent Blue Eyes: An innocent personality and big puppy-dog eyes to match.
- Lipstick Lesbian: A huge girly-girl, and in a happy relationship with a female lizard.
- Nice Girl: She's overall a friendly character.
- Odd Couple: With Lemonhead.
- Pink Means Feminine: The girliest of the cast, and has pink fur.
- Tertiary Sexual Characteristics: Has long eyelashes, and wears bows on her ears.
- Transgender: Lollipup is a transgender girl. This has been brought up a few times over the course of the series, most notably in the strip where Lollipup comes out to Liz.
- Adorkable: Though not to the extent of Lollipup, she's pretty goofy.
- Butch Lesbian: A Tomboy with a Girly Streak punk rocker, in a happy relationship with a female poodle.
- Latin Lover: Despite being female, she falls into this trope at times, when flirting with Lollipup. On one occasion she calls Lollipup "mi malvovisco pachoncito," which roughly translates to "my fluffy marshmallow."
- A Lizard Named "Liz": And how!
- Mellow Fellow: Has a relaxed, easy-going personality.
- Nice Girl: Overall a fairly pleasant person.
- Perky Goth
- Tertiary Sexual Characteristics: Downplayed- she's not very feminine, but still wears eyeliner.
- Tomboy with a Girly Streak: She's a butch lesbian. That being said, she seems to be pretty fond of wearing dresses- albeit paired with big combat boots. In the wedding comic, she's also shown wearing a dress.
- Adorkable: Gets a bit flustered when he asks Lemonhead out on a date.
- Affectionate Nickname: Calls Lemonhead "Lemon-Chan."
- Big Beautiful Man: He's a chubby dog, and Lemonhead seems to think he's cute.
- Dog Stereotype: A Japanese shiba inu.
- Nice Guy: He's a pretty nice shiba inu.
- Occidental Otaku: Hilariously subverted- he's a Japanese dog who's obsessed with American / cowboy culture.
- Remember the New Guy?: According to his introductory comic, he and Lemonhead have known each other for at least a little while, attending the same book club together.
- The Smart Guy: Attends a regular book club, and likes discussing movies. He also appears to be bilingual.