History WesternAnimation / OzzyAndDrix

* VerySpecialEpisode: The smoking episode, though most of the episodes cover something related to health or safety and have AnAesop related to it.

* DiseasePreventionAesop: Nearly every episode has a lesson on staying healthy, which is logical, considering the main characters are medication and a white blood cell.

* AnthropomorphicPersonification: See below.

* GenderBender: Osmosis turning into a female, when he ends up inside Christine's body in the episode "An Out of Body Experience".

* AllYourBaseAreBelongToUs: In one episode a gang of testosterone managed to stage a ''coup d'etat'' within Hector through a combination of peer pressure and cunning. Unsurprisingly, their leader promptly used his newfound power to turn Hector into a frat boy.

* AllYourBaseAreBelongToUs: In one episode a gang of testosterone managed to stage a coup d'etat within Hector through a combination of peer pressure and cunning. Unsurprisingly, their leader promptly used his newfound power to turn Hector into a frat boy.

* AesopAmnesia: The spin-off's first episode shows that whatever Frank learned about health didn't stick, and his life seems to have spun out of control. For the brief time we see him, he's eating chicken in a trailer park. A more friendly interpretation would be that the cartoon is set in an AlternateContinuity, where the film's plot didn't happen; note that Shane isn't present, and that Ozzy, despite his accomplishments in the film, mentions being on Snot Patrol in the pilot episode. Even the garage Thrax took refuge in, then burned to the ground, is intact.

* BigEater: Hector's fat cells, due to it being their sole purpose. Especially since Hector has been eating a lot lately in "A Growing Cell".

** Subverted in "An Out of Body Experience Pt.2", when Drix tries hacking Hector's fear center to undo his fear of swimming. The network turns out to be too difficult for him to decode, but Hector ends up overcoming his fear himself.

* CatchPhrase: "I'm unbeatable!" for Nick'O Teen. [[spoiler:Becomes his last words as he shrinks away to nothing and is stomped out by Ozzy after Hector refuses a second cigarette.]]

* ClippedWingAngel: [[spoiler:Nick'O Teen burns himself out trying to brute force Hector to smoke again after Hector refuses, reduced to a pathetic powerless form, that Ozzy finishes off by stepping on him.]]

* HappyEndingOverride: ''Film/OsmosisJones'' ended with Frank strongly implied to have changed his habits after nearly dying, but the pilot shows he's resumed his prior unhealthy lifestyle (before Ozzy, Drix, and Scarlet Fever are transferred to Hector by a mosquito). That said this is a more vague example as there are various hints that this show takes place in an alternate continuity, making it ambiguous if there was a happy ending to override.

** Attempted again in "Out of Body Experience", when they need Hector to go back in the pool with Christine so Ozzy (who got stuck in Christine's body) can swim home, but Hector's near-drowing experience left him afraid of swimming. They ultimately fail, but Hector's crush on Christine overrides his fear anyway.

** In "A Cold Day in Hector" Drix is the only one unaffected by the rapidly dropping hypothermic temperature in Hector's body due to not being a cell. This comes in handy when Ozzy begins to succumb to the cold, at one point becoming delirious.

* OhCrap: In "An Out-Of-Body Experience part 2", Ozzy has this reaction when he manages to call Drix, who tells him that if he stays in Christine’s body for too long, he’ll become a female cell.

** When he overrides Hector's pleasure center, Nick'O Teen assumes a larger, more monstrous form.

** Nick-O'teen and his gang are also dangerous chemicals, which make them unique, dangerous and difficult to deal with.

* PetTheDog: [[spoiler:One of Nick'O Teen's henchmen gets zapped by a high voltage nerve cell, the other two try to pull him free and save him despite otherwise being as bad as their boss. This only results in them all getting caught in the blast and destroyed for their trouble though.]]

* UngratefulBastard: Mayor Spryman, Ozzy saves his ass more often then not and the little jerk can't even give a "thank you".

* VillainousBreakdown: [[spoiler:Nick 'O Teen after Hector refuses to smoke of his own free will after Nick has already rewired his pleasure center. Nick tries to force him to, only to physical burn himself out and reduce himself to a tiny, weak form.]]

* TheWildcats: Hector's school nickname. For once, this trope is used ''without'' being abused.

* GenderBender: Osmosis turning into a female, when he ends up inside a girl's body.

** A villainous example: The Lead Gang is completely immune to anything the cells in Hector or Drix can throw at them due to being heavy metals and commercials. That's why they need to get Hector to eat cereal to bring in stronger vitamins and minerals to do the job.

** Nick-O'teen and his gang are also dangerous chemicals, which make them unique dangerous and difficult to deal with.