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Icewind Dale: Rime of the Frostmaiden
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A curse of Endless Winter is cast upon Icewind Dale, causing a slew of crises and other troubles for resilient adventurers to resolve before taking on the Evil God responsible for said curse.
OR
Dungeons & Dragons meets The Thing (1982) and At the Mountains of Madness.
Feel the cold touch of death in the unabridged version here!