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General
- Liquid Cooling is a fairly strong cryo-only Skulldugger pistol that actually loses heat when you get a critical hit, severely neutralizing Skulldugger's one major weakness. If there's one thing you want in the Chaos Chambers, it's this. Also, it can roll a X2 mod. Sadly, a mid-April 2022 hotfix nerfed its damage by 60% (later reduced to 40%). "Works great until it doesn't" indeed...
- Ruby's Spite is a dark magic-only Dahlia crossbow pistol that, upon getting a kill with it, temporarily gains majorly boosted firing rate and homing projectiles. So long as you can keep getting timely kills with it, this becomes perfect for quickly clearing out a room.
- Red Hellion, the fantasy counterpart of The Butcher shotgun is just as much of a game breaker as it shreds through enemies and melt bosses' lifebars like butter. The main difference is that depending on how fast you run, it can fire more bullets.
- The Masterwork Handbow, thanks to its guaranteed high Gun Damage and Critical Hit Damage mods, is one of the highest base damage guns in the game, with the catch that it only has a 1 bullet magazine. But if you can successfully get a Crit with it, not only will it likely one-shot any normal enemy, but it'll fire out bullets that hit all other enemies nearby and immediately replenish the magazine, allowing you to rapid fire it if you can consistently hit a Critical Hit Zone. It's also spectacularly useful for Spellshot builds, due to their reliance on reloading for shield recovery.
- The Buffmeister spell is one of the most powerful active buff items in the series. Upon activating it, you get +60% move speed, you get added damage of an element which for low-damage-fast-firing weapons like SMGs will double/triple their damage output, and a massive power boost for up to two of Gun/Spell/Ability/Melee. Thanks to a Good Bad Bug on release, Spellshots who use Ambihexterous can put the Buffmeister in the right slot and a high damage spell in the left slot; the added damage from the Buffmeister spell will instead use the left slot, allowing you to add thousands of damage per bullet instead and completely trivialize everything. On top of all that, it can potentially spawn with an extra charge, making its cooldown pretty much a non-issue. Unfortunately, the April 2022 patch fixed the right-hand damage exploit.
- Queen's Cry is the queen of Frost guns, particularly after the significant Liquid Cooling nerf noted above. It has a native 3x bullets not shown on the gun card, and it can also roll a X2 mod for 6 bullets per shot, with a much higher base damage than Frost X4 SMGs. As a bonus, critical hits can spawn a delayed meteor which deals a significant amount of damage in an area and also helps clean up hazards spawned on death in Chaos Chambers. It can also roll with a very valuable Taser attachment. The only downsides are that ammo consumption is extremely high and the meteor spawned can hurt you if not careful.
- "Double dipping" with skills like the Spellshot's Double Knot and the Graveborn's Blast Gasp allow the bonus damage of those skills to benefit from multiplicative bonus modifiers twice (once as the initial damage, again as the bonus damage), which can result in exponential damage and one-shotting enemies and bosses.
- A May 2022 hotfix buffed Torgue weapons and the Swordsplosion. Because of these, the Swordsplosion became an absolute powerhouse. Hit an enemy with a bunch of sticky projectiles (made easier because of the fire rate and projectile speed buffs), then reload and watch the health bars vanish in a flash.
- The quest reward gun, Last Rites of Sunless Depths, is a cryo-only Hyperious shotgun that already has great damage output, good magazine size, and shots that chain to nearby enemies, making it great for destroying mobs. Its only weakness is a somewhat slow firing rate, plus needing it to spawn in vending machines for better versions.
- Fragment Rain is a cryo Feriore SMG that fires multiple small ice shards that ricochet when hitting a target, damaging everything around you. Chances are, by the time you've taken down your current target, you'll turn to face your other opponents, only to find them already dead.
- The Wizard's Pipe is a versatile Hyperius SMG that always deals elemental damage and can deal even more with homing elemental orbs that home in on enemies that spawn during continuous fire. Said orbs always adjust to the enemy's health bar type, meaning that its primary elemental damage doesn't always have to match the orbs it spawns. It's an effective weapon against all enemy types as a result.
- Glutton's Gamble gives us the Stab-o-matic, the return of the Facepuncher from Borderlands 3. Like the Facepuncher, the projectiles deal melee damage instead of gun damage. With all the ways to improve your melee damage here, it has much more potential to be a beast. Combine this with a Soldier necklace and every single pellet has a 30% chance to refill the magazine, so you'll basically never need to reload as long as you're landing shots. And yes, it does work on loot enemies that are only vulnerable to melee damage.
- It's not just legendaries that can shred things anymore. There's plenty of strong purples that can cause carnage as well.
- The Torgue guns, Encrapsulator (crossbow rifle), Bawdyrocker (shotgun), and Lewdite (crossbow pistol) in sticky mode can do enough damage to singlehandedly carry you to the highest chaos levels. Get one in the element your class specializes in and you'll find yourself at the end of a run before you know it.
- Hyperious and Dahlia Nightshade SMGs with a x4 or x5 multiplier are simple, yet versatile damage dealers.
- Pixie Companions spawned from reloading Feriore weapons are able to track targets by themselves, navigating around obstacles and doing high damage with rapid fire bursts. But what especially makes pixies Game Breakers is their interaction with skills: Spell Damage pixies, for example, can trigger the double-dipping skills noted above and will do so very often with their rapid fire. For best results, use the Fearnot pistols, since they reload faster and let you spam pixies faster.
- A x2 cryo Skuldugger Scalawag pistol can be a great substitute for the Liquid Cooling, since it still has the damage potential, just no ability to quickly reduce heat.
- A Blackpowder pistol with a grip that provides multi-shots is essentially a lesser Maggie from Borderlands 3; a reliable Jakobs pistol that deals non-elemental damage very quickly.
Clawbringer
- The Storm Dragon's Judgement attack can be retracted for an ability cooldown rebate, meaning that this ability can be spammed more frequently. Combine this with various ability-triggered effects and said effects can take effect on a greater whim. Of note is the Harbinger Amulet, which instantly restores half of the player's maximum ward. This turns the Storm Dragon's Judgement into an effective panic button for filling up wards in the heat of battle.
Stabbomancer
- With the combination of the capstone skill, Executioner's Blade, a Soldier necklace (chance to refill magazine on melee hit), and a Torgue sticky weapon, the ghost weapons can potentially trigger the magazine refill, allowing you to stick enemies with many more projectiles and make the damage absolutely skyrocket.
