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* ''WesternAnimation/BobsBurgers'': In the episode ''Aquaticism'' the IRS agent that the kids have been duping, fully buys their fake religion and decides to baptize himself by getting in the jellyfish tank. It does not go well.

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* ''WesternAnimation/TheHouse2022:'' Over the course of Chapter 2,
[[spoiler: the bug infestation of the House, the lack of prospective buyers, and the presence of a family of mysterious squatters all end up driving the Developer to the brink of a breakdown... and in the finale, the realization that the squatters are actually giant versions of the insects pushes the Developer over the edge: when he's next seen, the anthropomorphic rat has [[UnanthropomorphicTransformation regressed to animal intelligence]], now crawling on all fours and living in a burrow behind the oven - and he's also chewed off most of his hospital gown, leaving him naked except for his fur.]]

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* ''WesternAnimation/TheHouse2022:'' Over the course of Chapter 2,
2, [[spoiler: the bug infestation of the House, the lack of prospective buyers, and the presence of a family of mysterious squatters all end up driving the Developer to the brink of a breakdown... and in the finale, the realization that the squatters are actually giant versions of the insects pushes the Developer over the edge: when he's next seen, the anthropomorphic rat has [[UnanthropomorphicTransformation regressed to animal intelligence]], now crawling on all fours and living in a burrow behind the oven - and he's also chewed off most of his hospital gown, leaving him naked except for his fur.]]

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Not necessarily to spoiler mark the whole thing.


* ''WesternAnimation/TheHouse2022:'' [[spoiler: Over the course of Chapter 2, the bug infestation of the House, the lack of prospective buyers, and the presence of a family of mysterious squatters all end up driving the Developer to the brink of a breakdown... and in the finale, the realization that the squatters are actually giant versions of the insects pushes the Developer over the edge: when he's next seen, the anthropomorphic rat has [[UnanthropomorphicTransformation regressed to animal intelligence]], now crawling on all fours and living in a burrow behind the oven - and he's also chewed off most of his hospital gown, leaving him naked except for his fur.]]

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* ''WesternAnimation/TheHouse2022:'' [[spoiler: Over the course of Chapter 2, 2,
[[spoiler:
the bug infestation of the House, the lack of prospective buyers, and the presence of a family of mysterious squatters all end up driving the Developer to the brink of a breakdown... and in the finale, the realization that the squatters are actually giant versions of the insects pushes the Developer over the edge: when he's next seen, the anthropomorphic rat has [[UnanthropomorphicTransformation regressed to animal intelligence]], now crawling on all fours and living in a burrow behind the oven - and he's also chewed off most of his hospital gown, leaving him naked except for his fur.]]
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* ''WesternAnimation/JusticeLeagueVsTheFatalFive:'' Star Boy has a schizophrenic episode that causes him to forget about his mission when he's transported to the past. He finds a pharmacy, and tries to speak with the pharmacist but considering his drug won't be invented for centuries it's a useless endeavor, he thinks that she's afraid of him because of his costume, cue him deactivating it, leaving him starkers and her terrified.
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[[folder:Films -- Animated]]
* ''WesternAnimation/TheHouse2022:'' [[spoiler: Over the course of Chapter 2, the bug infestation of the House, the lack of prospective buyers, and the presence of a family of mysterious squatters all end up driving the Developer to the brink of a breakdown... and in the finale, the realization that the squatters are actually giant versions of the insects pushes the Developer over the edge: when he's next seen, the anthropomorphic rat has [[UnanthropomorphicTransformation regressed to animal intelligence]], now crawling on all fours and living in a burrow behind the oven - and he's also chewed off most of his hospital gown, leaving him naked except for his fur.]]
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* ''VideoGame/{{Psychonauts 2}}'': One of the mental vaults in "Hollis's Hot Streak" shows Hollis Forsythe, in her old job as an unappreciated hospital intern, trying to rewrite the mind of her MeanBoss Dr. Potts so he'll confess to [[PlagiarismInFiction stealing her work]]. She accidentally caused Potts to go completely off the deep end and run around the hospital while stripping down to his underwear.
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* In ''Film/DriveHeSaid'' [[spoiler: Gabriel enters a psychotic break which causes him to strip naked and FreeTheFrogs]].
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* Throughout ''Literature/{{Repeat}}'', Brad Cohen's GroundhogDayLoop-induced immortality [[WhoWantsToLiveForever slowly erodes his composure]] [[TimeLoopFatigue as time goes on]], eventually culminating in a failed attempt to reunite with Juliet and a psychological meltdown. Here, Brad goes for [[WanderingWalkOfMadness a very confused walk along Lake Michigan]] that ends with him taking all his clothes off - despite the bitter cold - and screaming at the sky.

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* Throughout ''Literature/{{Repeat}}'', Brad Cohen's GroundhogDayLoop-induced immortality [[WhoWantsToLiveForever slowly erodes his composure]] [[TimeLoopFatigue as time goes on]], eventually culminating in a failed attempt to reunite with Juliet and a psychological meltdown. Here, Left utterly shattered, Brad goes for [[WanderingWalkOfMadness a very confused walk along Lake Michigan]] that ends with him taking all his clothes off - despite the bitter cold - and screaming at the sky.
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* Throughout ''Literature/{{Repeat}}'', Brad Cohen's GoundhogDay-induced immortality [[WhoWantsToLiveForever slowly erodes his composure]] [[TimeLoopFatigue as time goes on]], eventually culminating in a failed attempt to reunite with Juliet and a psychological meltdown. Here, Brad goes for [[WanderingWalkOfMadness a very confused walk along Lake Michigan]] that ends with him taking all his clothes off - despite the bitter cold - and screaming at the sky.

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* Throughout ''Literature/{{Repeat}}'', Brad Cohen's GoundhogDay-induced GroundhogDayLoop-induced immortality [[WhoWantsToLiveForever slowly erodes his composure]] [[TimeLoopFatigue as time goes on]], eventually culminating in a failed attempt to reunite with Juliet and a psychological meltdown. Here, Brad goes for [[WanderingWalkOfMadness a very confused walk along Lake Michigan]] that ends with him taking all his clothes off - despite the bitter cold - and screaming at the sky.

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* ''Literature/TheBoneMaker'': One MadOracle took to spending his days naked in a public fountain in a busy market square. The choice of locale was intended to drown out his visions with mundane noise; the lack of clothing was presumably because he's [[BarefootPoverty dead broke]] and unhinged from reality.



* Throughout ''Literature/{{Repeat}}'', Brad Cohen's GoundhogDay-induced immortality [[WhoWantsToLiveForever slowly erodes his composure]] [[TimeLoopFatigue as time goes on]], eventually culminating in a failed attempt to reunite with Juliet and a psychological meltdown. Here, Brad goes for [[WanderingWalkOfMadness a very confused walk along Lake Michigan]] that ends with him taking all his clothes off - despite the bitter cold - and screaming at the sky.



* ''Literature/TheBoneMaker'': One MadOracle took to spending his days naked in a public fountain in a busy market square. The choice of locale was intended to drown out his visions with mundane noise; the lack of clothing was presumably because he's [[BarefootPoverty dead broke]] and unhinged from reality.

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* ''Skull Island: The Birth of Kong'': In this Franchise/MonsterVerse graphic novel, [[Characters/MonsterVerseSkullIslandExpedition Riccio]] during his SanitySlippage. First he strips his upper-body down to just his undershirt upon coming in contact with the Iwi, then as he integrates himself into their culture and his SanitySlippage progresses, he goes around topless for the rest of the story, up until he dons an Iwi robe just before his death.



* {{Downplayed}} in ''[[ComicBook/MarshalLaw Marshal Law: Kingdom of the Blind]]''. The Private Eye, an evil ComicBook/{{Batman}} expy, is first shown getting up from sleeping naked and putting on his costume. This isn't odd in of itself, but the nudity foreshadows that he beats up criminals because he's a weird pervert.
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* Myth/ArthurianLegend: The first story about Yvain has him go crazy and live naked in the woods, basically because of a fight with his wife. Morgan le Fay finds and heals him (which probably inspired later stories where she's his mother).
** When Guinevere catches Lancelot in bed with Elaine[[note]][[BedTrick She tricked him]]. ''Again.'' Arthuriana can be very repetitive.[[/note]], he jumps out the window, naked, and runs around crazy for a while. Eventually he finds his way to Elaine's home, where she takes care of him until he regains his sanity and lives with her for a while.
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* In the ''WesternAnimation/{{Daria}}'' episode "The Teachings of Don Jake", Jake, Helen and Quinn all eat the poisonous berries and begin hallucinating -- during which, Jake strips down to his underwear.

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* In the ''WesternAnimation/{{Daria}}'' episode "The Teachings of Don Jake", Jake, Helen Helen, and Quinn all eat the poisonous berries and begin hallucinating -- during which, Jake strips down to his underwear.
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** Then he gets into a workplace dispute and quits his job, this leaves him with no income whatsoever and continues his downward spiral, during this time he's usually seen only wearing underpants or a towl, sometimes stripping completely.

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** Then he gets into a workplace dispute and quits his job, this leaves him with no income whatsoever and continues his downward spiral, during this time he's usually seen only wearing underpants or a towl, towel, sometimes stripping completely.
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* A recurring gag character on ''WesternAnimation/FamilyGuy'' is "the Greased-Up Deaf Guy," [[ExactlyWhatItSaysOnTheTin a man covered in cooking oil who runs around in his underwear and speaks in a high-pitched warble due to his lack of hearing]]. According to one episode, he was an ordinary white-collar worker before he got caught in a truck explosion.

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* Used in one of Literature/TheSaint's trademark eccentric metaphors, where he says that if you see someone tearing up the street naked, covered in blood and holding a cleaver, it may be that they've just got out of the bath, have killed a chicken, and are running off to tell their aunt all about it...but it might be better to just assume they're a homicidal maniac.

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* Used ''Literature/TheSaint'': Referenced in one of Literature/TheSaint's trademark eccentric metaphors, a LopsidedDichotomy by the title character, where he says that if you see someone tearing up the street naked, covered in blood blood, and holding a cleaver, it may be that they've just got out of the bath, have killed a chicken, and are running off to tell their aunt all about it...but it might be better to just assume they're a homicidal maniac.maniac.
* ''Literature/TheBoneMaker'': One MadOracle took to spending his days naked in a public fountain in a busy market square. The choice of locale was intended to drown out his visions with mundane noise; the lack of clothing was presumably because he's [[BarefootPoverty dead broke]] and unhinged from reality.
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None

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* {{Downplayed}} in ''[[ComicBook/MarshalLaw Marshal Law: Kingdom of the Blind]]''. The Private Eye, an evil ComicBook/{{Batman}} expy, is first shown getting up from sleeping naked and putting on his costume. This isn't odd in of itself, but the nudity foreshadows that he beats up criminals because he's a weird pervert.
Is there an issue? Send a MessageReason:
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* The Bjork stalker [[LoonyFan Ricardo Lopez]] spends a lot of time either half dressed or completely naked; what's interesting is that during his several hours long ApocalypticLog his level of derangement can be measured by the amount of clothes he wears:

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* The Bjork stalker [[LoonyFan Ricardo Lopez]] spends spent a lot of time either half dressed or completely naked; what's interesting is that during his several hours long ApocalypticLog his level of derangement can be measured by the amount of clothes he wears:
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* The Bjork stalker [[LoonyFan Ricardo Lopez]] spends a lot of time either half dressed or completely naked; what's interesting is that during his several hours long ApocalypticLog his level of derangement can be measured by the amount of clothes he wears:
** At first he usually just has his shirt off, during this time he was planning on killing Bjork but wasn't fully committed to it and still had a job.
** Then he gets a worried call from his mother, [[HopeSpot which temporally brings him back to reality and he decides to try and live a normal-ish life, even considering just letting his obsession with Bjork go]], during this time he is fully clothed (although admittedly still doing bizarre things while doing so).
** Then he gets into a workplace dispute and quits his job, this leaves him with no income whatsoever and continues his downward spiral, during this time he's usually seen only wearing underpants or a towl, sometimes stripping completely.
** And during the [[DrivenToSuicide final tapes]] he completely sheds all his clothing and shaves his head; wearing nothing but some black and red face paint before he AteHisGun
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* Used in one of Literature/TheSaint's trademark eccentric metaphors, where he says that if you see someone tearing up the street naked, covered in blood and holding a cleaver, it may be that they've just got out of the bath, have killed a chicken, and are running off to tell their aunt all about it...but it might be better to just assume they're a homicidal maniac.
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[[quoteright:350:[[Theatre/KingLear https://static.tvtropes.org/pmwiki/pub/images/king_lear.png]]]]
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* When the thunderstorm hits in ''Film/TheShout'', one of the mental patients who is fielding in the cricket game responds by stripping off all of his clothes, dancing in the rain and smearing himself with cow manure.
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* People suffering from schizophrenia sometimes get undressed as a result of their hallucinations. They might believe that they are the only people in the world for example, and therefore the nudity taboo doesn't apply anymore.
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* In ''[[Literature/TheBelgariad The Malloreon]]'' this is part of the villain Zandramas’ backstory. When the spirit of dark possessed her, she went temporarily insane and the first thing she did was strip down and run off naked into the forest. For the next few years she roamed the wilderness naked and only spoke to people in tongues, if she spoke at all. Eventually she comes back to the city, restored to her senses and fully clothed again.

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!!Examples

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!!Examples!!Examples:



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[[folder: Film - Live-Action]]
* The vampires in ''Film/{{Daybreakers}}'' begin to physically and mentally degenerate the longer they go without blood, ultimately devolving into insane BatPeople known as "Subsiders." The first one encountered in the film is so frenzied with hunger that he's resorted to [[{{Autocannibalism}} feeding on himself]], and has stripped completely naked - the better to show off his winged, inhuman body.

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[[folder: Film - [[folder:Films -- Live-Action]]
* The vampires in ''Film/{{Daybreakers}}'' begin to physically and mentally degenerate the longer they go without blood, ultimately devolving into insane BatPeople known as "Subsiders." "Subsiders". The first one encountered in the film is so frenzied with hunger that he's resorted to [[{{Autocannibalism}} feeding on himself]], and has stripped completely naked - -- the better to show off his winged, inhuman body.



* The plot of ''Film/DrTAndTheWomen'' truly kicks off when Kate Travis mentally regresses to childhood, strips off all her clothes, and plays naked in a nearby fountain - resulting her being committed to a mental hospital.

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* The plot of ''Film/DrTAndTheWomen'' truly kicks off when Kate Travis mentally regresses to childhood, strips off all her clothes, and plays naked in a nearby fountain - -- resulting her being committed to a mental hospital.



* ''Film/Everest2015'': It's repeatedly stated how the low-oxygen environment affects the mind, sometimes resulting in people spontaneously taking their clothes off despite the cold (known as paradoxical undressing).
* During the backstory to ''Film/ExorcistTheBeginning'', Monsieur Bession went [[GoMadFromTheRevelation Mad From The Revelation]] after spending a little too much time at [[DugTooDeep the Turkana dig]] and had to be carted off to an asylum in Nairobi. When Merrin finally goes to see him in the latter half of the film, he's stripped down to his underwear - revealing that he's also scratched a swastika in his chest. Then he slices his throat before Merrin's stunned eyes.

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* ''Film/Everest2015'': ''Film/{{Everest|2015}}'': It's repeatedly stated how the low-oxygen environment affects the mind, sometimes resulting in people spontaneously taking their clothes off despite the cold (known as paradoxical undressing).
* During the backstory to ''Film/ExorcistTheBeginning'', Monsieur Bession went [[GoMadFromTheRevelation Mad From The from the Revelation]] after spending a little too much time at [[DugTooDeep the Turkana dig]] and had to be carted off to an asylum in Nairobi. When Merrin finally goes to see him in the latter half of the film, he's stripped down to his underwear - revealing that he's also scratched a swastika in his chest. Then he slices his throat before Merrin's stunned eyes.



* In Creator/RomanPolanski's ''Film/Macbeth1971'', as well as the 2006 film version, Lady Macbeth performs the classic "Out Damned Spot" SanitySlippage soliloquy while in the nude.

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* In Creator/RomanPolanski's ''Film/Macbeth1971'', ''Film/{{Macbeth|1971}}'', as well as the 2006 film version, Lady Macbeth performs the classic "Out Damned Spot" SanitySlippage soliloquy while in the nude.



** The eponymous villain is almost always naked and - judging by the demented laughter, frenzied chanting and animal cruelty - is barely sane. Plus, [[FanDisservice she's also extremely elderly]].
** After being accidentally stranded in the forest, [[WiseBeyondTheirYears Caleb]] finds himself face to face with the Witch herself. He later turns up back at the family farm, delirious, incoherent and stark naked. [[spoiler: It's not specified what the Witch did to Caleb, though [[RapeAsDrama the implications aren't nice]]; whatever happened, it eventually ends up killing him.]]
** At the very end of the film, [[spoiler: Thomasin plunges over the DespairEventHorizon after the rest of her family is killed, leaving her stranded alone at the farm with no means of providing for herself and no help for miles. Calling out to Black Phillip, she accepts a literal DealWithTheDevil and - at his prompting - strips nude and wanders out into the forest to join the other Witches. As she rises naked into the night with the rest of the coven, [[LaughingMad the look]] [[CryLaughing on her face]] indicates that she's finally crossed the line into madness.]]

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** The eponymous villain is almost always naked and - -- judging by the demented laughter, frenzied chanting and animal cruelty - -- is barely sane. Plus, [[FanDisservice she's also extremely elderly]].
** After being accidentally stranded in the forest, [[WiseBeyondTheirYears Caleb]] finds himself face to face with the Witch herself. He later turns up back at the family farm, delirious, incoherent and stark naked. [[spoiler: It's [[spoiler:It's not specified what the Witch did to Caleb, though [[RapeAsDrama the implications aren't nice]]; whatever happened, it eventually ends up killing him.]]
** At the very end of the film, [[spoiler: Thomasin [[spoiler:Thomasin plunges over the DespairEventHorizon after the rest of her family is killed, leaving her stranded alone at the farm with no means of providing for herself and no help for miles. Calling out to Black Phillip, she accepts a literal DealWithTheDevil and - -- at his prompting - -- strips nude and wanders out into the forest to join the other Witches. As she rises naked into the night with the rest of the coven, [[LaughingMad the look]] [[CryLaughing on her face]] indicates that she's finally crossed the line into madness.]]



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* ''Literature/TheMagicians:''

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* ''Literature/TheMagicians:''''Literature/TheMagicians'':



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* ''Series/BreakingBad'', "[[Recap/BreakingBadS2E3BitByADeadBee Bit By A Dead Bee]]": {{Exploited|Trope}} by Walt when he needs an alibi for his absence after being kidnapped by Tuco. Having managed to hitch a lift back into town, he wanders into a supermarket, stripping naked with a vacant stare, and [[PlayingSick passes it off]] as a days-long fugue state brought on by stress over his terminal illness.

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* ''Series/BreakingBad'', "[[Recap/BreakingBadS2E3BitByADeadBee Bit By A by a Dead Bee]]": {{Exploited|Trope}} by Walt when he needs an alibi for his absence after being kidnapped by Tuco. Having managed to hitch a lift back into town, he wanders into a supermarket, stripping naked with a vacant stare, and [[PlayingSick passes it off]] as a days-long fugue state brought on by stress over his terminal illness.



* In ''Series/Watchmen2019'', the first indication that Adrian Veidt has gone a little bit loopy in the decades following his victory is a scene in which he's found stark naked and writing while a servant massages his leg muscles. [[spoiler: He's actually been banished to a PrisonDimension on Europa, and spending several years trapped with only sycophantic servants for company has left him ever-so-slightly deranged.]]

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* In ''Series/Watchmen2019'', ''Series/{{Watchmen|2019}}'', the first indication that Adrian Veidt has gone a little bit loopy in the decades following his victory is a scene in which he's found stark naked and writing while a servant massages his leg muscles. [[spoiler: He's [[spoiler:He's actually been banished to a PrisonDimension on Europa, and spending several years trapped with only sycophantic servants for company has left him ever-so-slightly deranged.]]



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** The hard-line [[{{Druid}} Verbena]] sect known as the Lifeweavers are so close to nature that they may reject wearing clothes for long periods of time. For this reason and more, they are often stereotyped - even by other Verbena mages - as being deranged to the point of losing human identity altogether; however, this is ultimately a subversion: despite their rejection of human civilization and (in extreme case) [[VoluntaryShapeshifting even the human form]], Lifeweavers rarely cross the line into madness.

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** The hard-line [[{{Druid}} Verbena]] sect known as the Lifeweavers are so close to nature that they may reject wearing clothes for long periods of time. For this reason and more, they are often stereotyped - -- even by other Verbena mages - -- as being deranged to the point of losing human identity altogether; however, this is ultimately a subversion: despite their rejection of human civilization and (in extreme case) [[VoluntaryShapeshifting even the human form]], Lifeweavers rarely cross the line into madness.



** Having been pushed to the very fringes of society by misfortune and the excesses of more successful vampires, the [[FeralVampires Strigoi bloodline]] has gradually degenerated into insanity: some exist in a state of animalistic rage, others embrace delusions of their former courtly life even while living in graveyards or caves. As such, most of them wear next to nothing - and it's noted some are so deluded that they may actually believe their ragged loincloths to be the finest robes.
* ''TabletopGame/VampireTheMasquerade:''

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** Having been pushed to the very fringes of society by misfortune and the excesses of more successful vampires, the [[FeralVampires Strigoi bloodline]] has gradually degenerated into insanity: some exist in a state of animalistic rage, others embrace delusions of their former courtly life even while living in graveyards or caves. As such, most of them wear next to nothing - -- and it's noted some are so deluded that they may actually believe their ragged loincloths to be the finest robes.
* ''TabletopGame/VampireTheMasquerade:'' ''TabletopGame/VampireTheMasquerade'':



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[[folder: Video Games]]

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-->'''Dumbledore''': ''[[CatchPhrase Naked time!]]''

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-->'''Dumbledore''': -->'''Dumbledore:''' ''[[CatchPhrase Naked time!]]''



[[folder: Western Animation]]

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[[folder: Western [[folder:Western Animation]]



* In the ''WesternAnimation/{{Daria}}'' episode "The Teachings of Don Jake", Jake, Helen and Quinn all eat the poisonous berries and begin hallucinating - during which, Jake strips down to his underwear.

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* In the ''WesternAnimation/{{Daria}}'' episode "The Teachings of Don Jake", Jake, Helen and Quinn all eat the poisonous berries and begin hallucinating - -- during which, Jake strips down to his underwear.



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[[/folder]][[/folder]]
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* In the finale of the ''WesternAnimation/RickAndMorty'' episode "Rixty Minutes," the alternate Jerry Smith ends up suffering a meltdown that begins with him stripping down to his underwear; by the time the Smiths catch up with the news report, he's already shaved off a huge chunk of his hair, tried to cut off his toe and eat it, been resuscitated by the medics, stolen a mobility scooter and led the police on a LowSpeedChase across town.

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* In the finale of the ''WesternAnimation/RickAndMorty'' episode "Rixty Minutes," "[[Recap/RickAndMortyS1E8RixtyMinutes Rixty Minutes]]," the alternate Jerry Smith ends up suffering a meltdown that begins with him stripping down to his underwear; by the time the Smiths catch up with the news report, he's already shaved off a huge chunk of his hair, tried to cut off his toe and eat it, been resuscitated by the medics, stolen a mobility scooter and led the police on a LowSpeedChase across town.

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* ''WesternAnimation/AdventureTime'': Early on in "You Made Me!", the Earl of Lemongrab (who suffers from an AmbiguousDisorder) runs through the streets of the Candy Kingdom tearing his clothes off while in the throes of a nervous breakdown.



* ''WesternAnimation/FostersHomeForImaginaryFriends'': Mac goes into a frenzy whenever he eats candy. In both episodes where his condition is triggered, he removes his clothes and runs around the city while screaming for more sugar.

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* ''WesternAnimation/FostersHomeForImaginaryFriends'': Mac [[GRatedDrug goes into a frenzy whenever he eats candy.candy]]. In both episodes where his condition is triggered, he removes his clothes and runs around the city while screaming for more sugar.

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[[folder: Music]]
* In the song "Crazytown" from ''35MM'', the main singer becomes this after being driven into insanity, stripping himself of clothes and hair as he realizes that where he's trapped in is not like the lands of fiction.
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* During ''ComicBook/LockeAndKey #4: Keys To The Kingdom'', Kinsey makes the mistake of revealing the [[CoolKey Head Key]] to Scott and Jamal, both of them opting to experiment with it at length. Unfortunately, this results in Scott having his sanity removed from his mind and deciding to perform Byron naked in front of the entire school, forcing his two friends to rescue him before he embarrasses himself any further.

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* During ''ComicBook/LockeAndKey #4: Keys To The Kingdom'', Kinsey makes the mistake of revealing the [[CoolKey Head Key]] to Scott Scot and Jamal, both of them opting to experiment with it at length. Unfortunately, this results in Scott Scot having his sanity removed from his mind and deciding to perform Byron naked in front of the entire school, forcing his two friends to rescue him before he embarrasses himself any further.



* In ''ComicBook/{{Tintin}}'', when the archaeologist Dr. Sarcophagus is poisoned with "madness poison", one of the first signs of insanity is that he takes his pants off.

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* In ''ComicBook/{{Tintin}}'', ''ComicBook/{{Tintin}}: Recap/TintinCigarsOfThePharaoh'', when the archaeologist Dr. Sarcophagus is poisoned with "madness poison", one of the first signs of insanity is that he takes his pants off.
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In fiction, there are many ways of indicating that a character has lost their sanity, some of them subtle, some of them not: disarrayed hair, haunted-looking eyes, filthy clothes, a habit of speaking to people who aren't there, a fixation on certain words or phrases, a tendency to sing inappropriately... or maybe the character has just given up on wearing clothes.

By far the ''least'' subtle indication of mental woes, characters who exhibit this symptom demonstrate their burgeoning insanity by stripping down. A few modest variants on this theme may leave their underwear on, or at the very least only qualify as a WalkingShirtlessScene; an even rarer few might actually have a good reason for going nude - one that make sense to ''them'', anyway; the rest are more than happy to wander around completely naked for no apparent reason whatsoever.

May overlap with NakedPeopleAreFunny. May involve FanDisservice, especially if the scene is played for horror or revulsion. See BarefootLoon when this is restricted to a lack of footwear.

Compare and contrast FullFrontalAssault, which is most commonly concerned with people ''fighting'' in the nude (sane or otherwise).
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!!Examples
[[foldercontrol]]

[[folder: Comic Books]]
* In the first issue of ''ComicBook/FallOfCthulhu'', Sy finds a Cthulhu-worshipping priest naked and conducting a ritual at the Arkham Boarding House; worshipers of the Great Old Ones are often insane or deluded, and this one's no exception: not only is he covered in ritual markings, but he goes on to conduct a shockingly light-hearted discussion with Sy - [[MajorInjuryUnderreaction despite having just]] ''[[GroinAttack cut off one of his own testicles]].'' And then [[DrivenToSuicide he slits his throat]].
* During ''ComicBook/LockeAndKey #4: Keys To The Kingdom'', Kinsey makes the mistake of revealing the [[CoolKey Head Key]] to Scott and Jamal, both of them opting to experiment with it at length. Unfortunately, this results in Scott having his sanity removed from his mind and deciding to perform Byron naked in front of the entire school, forcing his two friends to rescue him before he embarrasses himself any further.
* Being insane, ComicBook/NormanOsborn AKA the Green Goblin has demonstrated this on occasion:
** During ''ComicBook/DarkReign'', Norman spent one night in his office, completely naked, clutching at his face and saying "Why won't this mask come off?"
** In the Warren Ellis retool of ''ComicBook/{{Thunderbolts}}'', Norman begins cracking up when telepaths mess with the minds of everyone in Thunderbolt Mountain and gets back into his Green Goblin costume for the first time in a while - all while ranting insanely to himself about what he'd do if he were president. After undressing, he takes a little while to take the next step into actually donning the costume, leaving him stark naked in mid-rant... and resulting in ''this'' immortal line:
--->Note to self: give naked dictation more often, the ideas seem to flow more freely.
* In ''ComicBook/{{Tintin}}'', when the archaeologist Dr. Sarcophagus is poisoned with "madness poison", one of the first signs of insanity is that he takes his pants off.
[[/folder]]

[[folder: Film - Live-Action]]
* The vampires in ''Film/{{Daybreakers}}'' begin to physically and mentally degenerate the longer they go without blood, ultimately devolving into insane BatPeople known as "Subsiders." The first one encountered in the film is so frenzied with hunger that he's resorted to [[{{Autocannibalism}} feeding on himself]], and has stripped completely naked - the better to show off his winged, inhuman body.
* Late in ''Film/TheDevilsAdvocate,'' Mary-Anne Lomax's SanitySlippage comes to a head when she randomly shows up in a church, shrouded in a blanket and clearly very badly traumatized. She eventually reveals to Kevin that [[spoiler: she's just been raped by John Milton]], but Kevin denies this as the perpetrator was in court with him the whole afternoon - whereupon Mary-Anne tosses the blanket aside, revealing herself to be completely naked and ''[[FanDisservice covered in bloody scratches]].'' [[spoiler: Despite being deliberately driven to a nervous breakdown, she was not imagining the rape; Milton is capable of being in two places at once, and later openly gloats over what he did to Mary-Anne.]]
* In ''Film/DoraAndTheLostCityOfGold'', when the main cast starts tripping due to hallucinogenic pollen, Alejandro takes off his clothes and runs around naked.
* The plot of ''Film/DrTAndTheWomen'' truly kicks off when Kate Travis mentally regresses to childhood, strips off all her clothes, and plays naked in a nearby fountain - resulting her being committed to a mental hospital.
* Throughout ''Film/EventHorizon'', the fate of the eponymous ship's crew has remained a mystery for most of the film. Towards the climax, the crew of the ''Lewis And Clark'' belatedly manage to find a video log of what happened: [[spoiler: as soon as they activated the gravity drive, [[HyperspaceIsAScaryPlace everyone on board descended into violent madness and murdered each other in a variety of hideous ways]] - many of the perpetrators being undressed at the time. The final shot is of the blood-splattered captain sitting in front of the camera, stark naked '''and [[EyeScream holding his own eyeballs in his outstretched hands]].''']]
* ''Film/Everest2015'': It's repeatedly stated how the low-oxygen environment affects the mind, sometimes resulting in people spontaneously taking their clothes off despite the cold (known as paradoxical undressing).
* During the backstory to ''Film/ExorcistTheBeginning'', Monsieur Bession went [[GoMadFromTheRevelation Mad From The Revelation]] after spending a little too much time at [[DugTooDeep the Turkana dig]] and had to be carted off to an asylum in Nairobi. When Merrin finally goes to see him in the latter half of the film, he's stripped down to his underwear - revealing that he's also scratched a swastika in his chest. Then he slices his throat before Merrin's stunned eyes.
* ''Film/HorseGirl'' is about a woman who may or may not be experiencing SanitySlippage who thinks she is getting abducted by aliens, as she experiences missing time and often finds herself in places with no idea how she got there. In one scene, she's taking a ShowerOfAngst, then suddenly finds herself at her workplace completely nude. This signals to others that she's losing her mind, and she gets sent to a mental institution after this scene.
* [[FatherNeptune Thomas Wake]] of ''Film/TheLighthouse'' is quickly established as being obsessed with the Light to the point of not allowing Winslow anywhere near it; as it later becomes clear, this is becomes he spends several evenings in the lantern room, staring directly into the Light while completely naked and likely masturbating. [[spoiler: For good measure, it's never established if there's something genuinely supernatural about the Light, or if Wake is just crazy.]]
* In Creator/RomanPolanski's ''Film/Macbeth1971'', as well as the 2006 film version, Lady Macbeth performs the classic "Out Damned Spot" SanitySlippage soliloquy while in the nude.
* Creator/RogerCorman's "nurseploitation" movie ''Film/NightCallNurses'' features an opening scene in which a young woman suffering a psychotic break climbs to the roof, strips to nothing but a pair of panties, then jumps to her death.
* Captain Pinbacker of ''Film/{{Sunshine}}''. The ''Icarus I's'' commanding officer, he [[SpaceMadness grew steadily more obsessed with the sun]] as the ship drew closer to it, eventually abandoning the mission altogether and stranding everyone in orbit. When the crew of the ''Icarus II'' finally find him, he's basking naked in the sunlight, now openly worshipping the sun as a god. For good measure, [[BodyHorror he's covered in hideous burns and blisters]] from exposure to the harsh light, so it's likely that wearing clothes would be too painful for him anyway. In any event, this swiftly transitions into FullFrontalAssault.
* Downplayed in ''Film/TalladegaNightsTheBalladOfRickyBobby''. After a crash, Ricky jumps out of his car, takes off his jumpsuit, and starts running around in his underpants and helmet yelling about being on fire. This is the start of his mental breakdown.
* Having been temporarily brainwashed by Loki back in ''Film/TheAvengers2012,'' Dr Eric Selvig reveals that the incident had a disastrous effect on his mind when he reappears in ''Film/ThorTheDarkWorld'': he's recently been arrested - on camera - at Stonehenge after stripping down naked and loudly haranguing tourists.
* ''Film/TheWitch'':
** The eponymous villain is almost always naked and - judging by the demented laughter, frenzied chanting and animal cruelty - is barely sane. Plus, [[FanDisservice she's also extremely elderly]].
** After being accidentally stranded in the forest, [[WiseBeyondTheirYears Caleb]] finds himself face to face with the Witch herself. He later turns up back at the family farm, delirious, incoherent and stark naked. [[spoiler: It's not specified what the Witch did to Caleb, though [[RapeAsDrama the implications aren't nice]]; whatever happened, it eventually ends up killing him.]]
** At the very end of the film, [[spoiler: Thomasin plunges over the DespairEventHorizon after the rest of her family is killed, leaving her stranded alone at the farm with no means of providing for herself and no help for miles. Calling out to Black Phillip, she accepts a literal DealWithTheDevil and - at his prompting - strips nude and wanders out into the forest to join the other Witches. As she rises naked into the night with the rest of the coven, [[LaughingMad the look]] [[CryLaughing on her face]] indicates that she's finally crossed the line into madness.]]
[[/folder]]

[[folder: Literature]]
* ''Literature/{{CELL}}:'' A good deal of the [[OurZombiesAreDifferent phone crazies]] tear their clothes off during the initial "outbreak". Clay, the protagonist, during a lull in the [[ApocalypseHow apocalypse]], spots a man stark naked, ranting and raving gibberish, and stabbing at the air with [[ImprovisedWeapon a car aerial,]] covered in blood that isn't his.
* In ''Literature/FantasticBeastsAndWhereToFindThem'', it is mentioned that the notoriously eccentric Uric the Oddball tried to convince the Wizard's Council that the song of the Fwooper wasn't [[BrownNote detrimental to the mental health of the listener]] as commonly believed, but quite the reverse. At the time, he claimed that he had conclusive proof of the positive effects of the magical bird's song after listening to it for nearly three months; unfortunately, the fact that he showed up for the presentation wearing nothing but a dead badger on his head made the arguments a little less than convincing.
* In the ''Literature/JohnnyCatbiscuit'' book "Johnny Catbiscuit and the Abominable Snotmen", if [[NoseNuggets the snot]] from a Snotman hits a human, it will cause the human to go insane. The first symptom of this insanity is ripping off your clothes, although when the police got hit they had the decency to keep their underwear on.
* ''Literature/TheMagicians:''
** Inverted during the Fourth Year, in which getting naked seems to ''induce'' insanity: at the end of the TrainingFromHell in Antarctica, the UltimateFinalExam features the student magicians being charged with walking to the South Pole - naked, with only their magic to protect them. By now, everyone's been hit with PolarMadness to at least some degree, and the process of wandering naked through the ice with no company nearly reduces Quentin to a barely-sane automaton - to the point that he ends up falling into a crevasse at one stage and barely even notices.
** [[PureMagicBeing Niffins]] are driven insane by their transformation from human to magical energy, and in both the books and the comics, are commonly depicted as being composed of blue flame and stark naked.
* Subverted in ''Literature/{{Necroscope}}:'' in his introduction, [[VillainProtagonist Boris Dragonsani]] ritualistically prepares for [[InterrogatingTheDead necromantic study]] by stripping naked and using the corpse as a cushion, then butchering the body while still nude. Though the observers assume that Boris is some kind of lunatic, [[TheSpymaster Gregor Borowitz]] makes it abundantly clear that the necromancer is perfectly sane, a point he proves when Boris manages to uncover the truth and save Borowitz from a traitor [[FullFrontalAssault while still without a stich of clothing on him]]. [[spoiler: More to the point, when Boris actually ''does'' begin to slip into psychopathy as a result of being impregnated with a vampire symbiote, he remains fully clothed.]]
* Delusional SerialKiller Francis Dolarhyde of ''Literature/RedDragon'' most commonly carries out his murders naked, apparently so he can admire his blood-splattered body post-massacre - and it's for this reason that he commonly targets isolated homes.
* In ''Literature/RedDwarf: Infinity Welcomes Careful Drivers,'' Lister hits the DespairEventHorizon after finding out that he's been in stasis for three million years, [[EverybodysDeadDave his fellow crewmembers are all dead]], the ship's lost in deep space, and he's the last human in the universe. Not seeing any point in dressing from then on, he spends most of his time wandering around the ship completely naked in a bewildered stupor, usually while drunk and hallucinating; this remains the case until [[BenevolentAI Holly]] goes so far as to resurrect [[SitcomArchnemesis Rimmer]] as a hologram so Lister can have a bit of company.
* The backstory to the ''Literature/ASongOfIceAndFire'' features this in one of the many documented cases of Targaryen Madness: Rhaegel Targaryen was believed to have succumbed to insanity during the reign of Aerys I, becoming known for dancing naked through the Red Keep.
* In ''Literature/SisterPelagia and the Black Monk'', when [[spoiler:Lentochkin]] [[ObfuscatingInsanity pretends]] to have been DrivenMadFromTheRevelation of the eponymous Black Monk, he, among other things, strips himself naked and violently fights off any attempt to clothe him again -- which is very convincing in the ultra-conservative 19th century provincial Russian society of the book. Later on, Pelagia unwittingly supports his crazy act by discovering that the Black Monk traps his victims in [[BuriedAlive coffins]], inducing extreme {{Claustrophobia}}, which, in [[spoiler:Lentochkin's]] case, is made to appear to be triggered by merely wearing clothes.
* Subverted in ''Literature/TheTerror.'' Upon encountering Mr Hickey stark naked and dancing around in the Arctic wastes, Lieutenant Irving assumes that the caulker's mate has finally succumbed to PolarMadness. However, when he approaches, Irving realizes too late that Hickey has a very practical reason for being naked: [[spoiler: he's planning on killing Irving; he got naked because he didn't want to get incriminated by blood on his clothes and the dancing was to keep himself warm until Irving got within reach. FullFrontalAssault ensues.]]
* Creator/RobertAHeinlein's short story "The Year of the Jackpot". As a result of multiple historical cycles reaching a low point, increasing numbers of human beings are acting in a strongly irrational manner. One example is people suddenly taking off all of their clothing for no apparent reason.
[[/folder]]

[[folder: Live-Action TV]]
* Played for dark laughs in the ''Series/AmericanHorrorStoryHotel'' episode "[[Recap/AmericanHorrorStoryS05E06Room33 Room 33]]": John Lowe is found drunk and visibly cracking up in the face of all the {{gaslighting}} that's been heaped on him so far, but demands to be left alone when Liz Taylor tries to help him, insisting that "this is my breakdown, and I'm gonna have it!" Minutes later, he's seduced into a threesome with the ghosts of Agnetha and Vendela, resulting him in being splashed with blood mid-coitus. He flees the scene in a panic without bothering to put his clothes back on, arriving back at the front desk completely naked and covered in blood. Without missing a beat, Liz remarks "[[BrickJoke Looks like that breakdown's going well...]]"
* ''Series/BreakingBad'', "[[Recap/BreakingBadS2E3BitByADeadBee Bit By A Dead Bee]]": {{Exploited|Trope}} by Walt when he needs an alibi for his absence after being kidnapped by Tuco. Having managed to hitch a lift back into town, he wanders into a supermarket, stripping naked with a vacant stare, and [[PlayingSick passes it off]] as a days-long fugue state brought on by stress over his terminal illness.
-->'''Marie:''' I think it's just great that he's, y'know, back and he's feeling better. I just, I mean, he... naked. He was naked. ''Naked.'' In a supermarket. [[SkewedPriorities It wasn't Whole Foods, was it?]]
* ''Series/{{Eureka}}'': The episode "Purple Haze" has the entire town acting strangely for an unknown reason, including Taggert strolling around stark naked. At the end, after (relative) normalcy has been restored, he's seen wearing a long trenchcoat, buttoned up to the neck.
* ''Series/{{Frasier}}'': Niles, cracking under the pressure of dealing with his wife's pregnancy and his brother accidentally implying he was involved with a murder committed by his ex-wife, finally snaps when a barista at his coffee shop tells him they're out of straws ("Ah. The ''last straw.''") He immediately strips naked in full view of the coffee shop and sits down to read a newspaper, giggling.
* ''Series/TheGoodPlace'': In "[[Recap/TheGoodPlaceS3E04JeremyBearimy Jeremy Bearimy]]", after learning the truth about the afterlife, Chidi undergoes an existentialist crisis and wanders through a grocery store shirtless and muttering about nihilism. He gets better shortly.
* ''Series/{{Justified}}'': A very serious example in Season 3, where Quarles strips down before taking a huge amount of drugs and torturing Donovan.
* ''Series/{{Supernatural}}'', "[[Recap/SupernaturalS05E11SamInterrupted Sam, Interrupted]]": {{Exploited|Trope}} when Sam and Dean [[GoAmongMadPeople get themselves committed]] to a psychiatric hospital to [[HunterOfMonsters hunt an undercover monster]]. A nurse finds them spying in the morgue, so Dean drops his trousers and yells, "Pudding!" to divert suspicion.
-->'''Dean:''' Crazy works!
* In the first episode of ''Series/ThirtyRock'', Tracy's EstablishingCharacterMoment shows a flashback of him running down a highway in his underwear waving around a plastic lightsabre and yelling "I'm a Jedi!".
* In ''Series/Watchmen2019'', the first indication that Adrian Veidt has gone a little bit loopy in the decades following his victory is a scene in which he's found stark naked and writing while a servant massages his leg muscles. [[spoiler: He's actually been banished to a PrisonDimension on Europa, and spending several years trapped with only sycophantic servants for company has left him ever-so-slightly deranged.]]
* In ''Series/XenaWarriorPrincess'', one of the most common punishments visited by the gods is madness. When this happens to Xena herself, one of the symptoms she displays is an inability to dress herself or realize that she's naked in public.
[[/folder]]

[[folder: Mythology And Religion]]
* In ''Literature/BookOfDaniel,'' this is implied to happen to King Nebuchadnezzar when YHWH punished him with madness: the text says that "his body was wet with the dew of heaven."
* Similarly, it is implied in [[Literature/TheFourGospels the gospels of Mark and of Luke,]] when Jesus cast the "Legion" demons out of the Gadarene man. Both writers specify that one of the things the crowd was astonished to see was that the former demoniac was ''clothed.''
[[/folder]]

[[folder: Poetry]]
* "The Ballad of Lucy Jordan" by Creator/ShelSilverstein, telling the story of a suburban housewife going mad, mentions as some of the "oh so many ways" Lucy Jordan can choose to spend her day with that "she could clean the house for hours / or rearrange the flowers / or run naked through the shady street / screaming all the way". The subsequent verses reveal that she is really doing the latter, resulting in her being carted off to a mental asylum.
[[/folder]]

[[folder: Tabletop Games]]
* ''TabletopGame/MageTheAscension:''
** The hard-line [[{{Druid}} Verbena]] sect known as the Lifeweavers are so close to nature that they may reject wearing clothes for long periods of time. For this reason and more, they are often stereotyped - even by other Verbena mages - as being deranged to the point of losing human identity altogether; however, this is ultimately a subversion: despite their rejection of human civilization and (in extreme case) [[VoluntaryShapeshifting even the human form]], Lifeweavers rarely cross the line into madness.
** According to the ''The Sorcerer's Crusade: Infernalism'', potential mages who have [[TraumaticSuperpowerAwakening Awakened]] under the guidance of the [[EvilSorcerer Nephandi]] often undergo a period in which they give vent to all the desires they previously denied. In rural areas, Fallen mages may end up stripping naked, eating raw meat and living among animals, degenerating into bestial madness until they either die or move onto better things.
** From the same book, the Infernalist templates feature a few of these: the [[TheMorlocks Catacomb Rat]] is a deranged sewer-dwelling beggar-mage that lost his sanity after falling through the cracks in society, existing as a "naked, leprous bundle of filth." Another, the [[WildChild Wildling]], is the living embodiment of the Lifeweaver stereotype, a crazed mage that has abandoned all notions of humanity in favour of living naked in the wilderness.
* In the TabletopGame/OldWorldOfDarkness crossover game ''Midnight Circus,'' it's mentioned that the [[TabletopGame/MageTheAscension Nephandus]] [[EvilSorcerer Devyn Cavendish]] managed to make his way into the uppermost ranks of the circus by becoming an apprentice to the current Ringmaster, a hedge wizard by the name of Mauritius. Once Cavendish had learned everything he could from his master, Mauritius was soon found inexplicably naked and barking like a dog - [[TheStarscream allowing Cavendish to claim the post of Ringmaster]]... but not before having his now-insane predecessor ripped to pieces by his own hounds.
* ''TabletopGame/{{Warhammer}}'':
** Dwarven Slayers have embraced the lifestyle of a DeathSeeker, and reportedly suffer from vicious bouts of depression and a pronounced lack of self-control. As they progress from Troll-slaying to Giant-slaying, they become increasingly crazed due to their lack of success in finding an honourable death, to the point that Daemon Slayers barely count as sane. However, regardless of their level of irrationality, all Slayers go into battle shirtless.
** [[OurGhoulsAreCreepier Ghouls]] have been driven insane by generations of cannibalism and necrophagia, and have lost so much of their mental faculties to that they barely understand the concept of weapons or clothing. Consequently, most go into battle wearing nothing more than loincloths.
** Having been pushed to the very fringes of society by misfortune and the excesses of more successful vampires, the [[FeralVampires Strigoi bloodline]] has gradually degenerated into insanity: some exist in a state of animalistic rage, others embrace delusions of their former courtly life even while living in graveyards or caves. As such, most of them wear next to nothing - and it's noted some are so deluded that they may actually believe their ragged loincloths to be the finest robes.
* ''TabletopGame/VampireTheMasquerade:''
** In the original Nosferatu clanbook, the character template "[[SerialKiller Leatherface]]" is depicted as completely naked except for the crude mask of bandages he wears. He's also soaked in blood and carrying around a severed head.
** According to the Baali clanbook, the [[DevilComplex Baalites]] were born when an unknown Cainite stumbled upon the city of Ashur and slaughtered all but three of them in progressively more hideous ways. The remaining three he Embraced by pouring his blood into the city's sacrificial well and throwing the dying trio in after it, creating the first Baalite vampires: when they finally emerged the next night, the three Fledglings were caked in gore from the corpses in the well and "howling with unquenched fury and madness" - and according to the accompanying image, naked as well.
* The Normalites of ''TabletopGame/WerewolfTheApocalypse''. The results of [[HeteronormativeCrusader Homogeneity Incorporated]] preying on insecure LGBTQ individuals, every single Normalite has been subjected to a treatment purported to "cure" homosexuality; unknown to the public, the company is a [[EvilCorp Pentex]] subsidiary and the treatments involve [[DemonicPossession Bane-possession]]. Patients at first appear contented with their new selves, only to become more and more intolerant towards any sign of social deviance as time goes on, until even the slightest difference prompts irrational rage. The final stage of the metamorphosis involves the newly-created Normalite degenerating into an insentient Fomori pack animal easily distinguished by its [[EyelessFace lack of eyes]], [[NonhumansLackAttributes lack of genitals]], irrational hatred of anything "unnatural", and - of course - constant nudity.
[[/folder]]

[[folder: Theatre]]
* ''Theatre/KingLear'': A couple of Lears - such as Creator/IanHolm and Creator/IanMcKellen - strip naked completely (and even more take off some of their clothes) in the heath scene where they bemoan the "naked wretches" and the "unaccommodated man" literally, when Lear is abandoned by Regan and Goneril outside in the storm.
[[/folder]]

[[folder: Video Games]]
* In the finale of ''VideoGame/Bioshock1'', [[spoiler: Frank Fontaine]] is [[VillainousBreakdown so desperate to defeat you]] that he resorts to splicing up with all the [[PsychoSerum ADAM]] he's stockpiled so far, quickly becoming just as crazed and delusional as all the other Splicers encountered throughout the game. When you finally catch up with him, he's stark naked - and so muscular he probably wouldn't be able to wear clothes anyway.
* Pandoran Psychos of the ''VideoGame/{{Borderlands}}'' series [[WalkingShirtlessScene never wear shirts]] except for the females of ''VideoGame/Borderlands3'' who wear [[BareYourMidriff midriff-baring tank tops]] or {{sarashi}}.
* Crops up towards the end of ''VideoGame/{{Control}}'': Dr Casper Darling, having been growing [[SanitySlippage progressively less composed]] throughout his video messages, is reduced to stripping down to his boxers in a shell-shocked trance as he acknowledges the disaster that lies before them [[spoiler: and the fact that he's beginning to transcend reality as a result of exposure to Hedron Resonance.]]
* In ''VideoGame/DarkSoulsI'', [[spoiler:after killing Seath and buying all of [[TheArchmage Big Hat Logan]]'s spells, Logan can be found in Seath's lair in the Duke's Archives stripped down to his underwear and [[WizardRobeAndHat hat]], having gone completely insane from his time spent in the Archives]].
* In ''VideoGame/DwarfFortress'', dwarves who become too upset can go insane in a variety of ways. One of them is becoming "Stark Raving Mad". Dwarves in this state take off all their clothes and run around aimlessly until they are calmed down, or die of starvation or dehydration.
* ''VideoGame/FateGrandOrder'': Roland of the Twelve Paladins of Charlemagne is said to have tried proposing to a queen named Angelica, but was rejected for being merely a knight. This caused Roland to go mad and he stripped naked before rampaging through France. In Astolfo's Interlude, Astolfo drags the player through France to try to see if Roland has materialized as a Servant, and it turns out that Roland ([[spoiler:well, a remnant of him]]) has gone on another naked rampage, leaving the citizens traumatized.
* Throughout the games of the ''VideoGame/FirstEncounterAssaultRecon'' franchise, [[BigBad Alma Wade]] remains completely naked in her adult form, and it's specifically stated that she'd been driven insane by [[RealityWarper her own powers]] long before she was locked in a vault for most of her life. For the most part, the only reason why she remains nude is because she was kept that way in the vault (and because it's pretty damn creepy). However, the second game in the series gives her a very good reason for being naked: [[spoiler: she's lusting after Beckett, and goes so far as to rape him in the finale.]]
* ''VideoGame/GrandTheftAutoV:''
** Trevor's list of disorders and personal problems would probably last long than the entire article, all adding up to one [[HairTriggerTemper extremely temperamental]], [[DrugsAreBad drug-addicted]], [[BloodKnight violent]] [[TheSociopath psychopathic]] [[VillainProtagonist criminal mastermind]]... and from time to time, he ends up stripped down to his underwear in public, usually while doing something spectacularly irrational.
** The Altruist Cult consists entirely of cannibalistic baby boomers who believe that they can regain their health by feeding on younger generations... and, as part of their ethos, often go around partially or ''completely'' naked. HilarityEnsues when they interact with Trevor.
* Occurs throughout ''VideoGame/{{Outlast}}''. Set in a dilapidated mental hospital now being run as a research laboratory by the Murkoff Corporation, several demonstrably-insane patients go about their day in various states of undress: [[TheJuggernaut Chris Walker]] is a WalkingShirtlessScene, a few [=NPCs=] are missing shirts or trousers, quirky psychopath [[MadDoctor "Dr" Rick Trager]] dresses only in an apron, cannibal Frank Manera is permanently stripped down to his undies, and [[CreepyTwins the cold-hearted Twins]] casually wander around wearing nothing whatsoever.
* Ditto ''VideoGame/OutlastII'', in which the Heretics wear nothing apart from mud and twigs, usually while being just as violent, irrational and zealous as the cultists of Temple Gate. Their leader, Val, usually wears a cassock to distinguish herself from her followers; however, in the climax of the game, she strips naked and daubs herself with mud before attacking Blake head-on. [[spoiler: This likely leads to Val raping him while he's in the middle of another dream sequence.]]
* ''VideoGame/PoliceQuestIIITheKindred'' has Brian Forbes, a guy who's only wearing his undies [[spoiler:and has a knife hidden in them]] who's causing problems at Aspen Falls due to babbling about Bathonians, being clearly in a deranged state of mind.
* ''VideoGame/TheSecretWorld:''
** According to Richard Sonnac, the Templars permanently vetoed all future efforts to map out [[EldritchLocation the realm of]] [[PortalCrossroadWorld Agartha]] after one of their best cartographers [[GoMadFromTheRevelation went mad in the attempt]]. When they finally found him, the guy was not only covered in his own filth and babbling in Enochian, but also bollock naked.
** In the 1960s, the [[HauntedHouse Devore Mansion]] on Solomon Island played host to a hippie commune of artists - up until the poet Billy Lee uncovered Frank Devore's Illuminati library hidden in the walls. After reading some of the more worrying tomes, he began slowly spiraling into insanity, exhibiting nightmares, paranoia, insomnia and a growing obsession with "dark gods," culminating in the massacre of the entire commune. When the police finally found Billy, he was naked in the nearby Moon Bog, "screeching prayers to [[EldritchAbomination the ones who dream]]."
* ''VideoGame/SouthParkTheStickOfTruth:'' When the kids has to confess to the Big Bad Government Guy about the purpose of the Stick of Truth, he immediately grows mad with power when holding the Stick and claims that nobody can control him and can do what he wants, which includes [[FanDisservice stripping naked in front of a couple of young boys]].
* In ''VideoGame/UntilDawn,'' the ultimate threat on the mountain spends the overwhelming majority of the game almost completely naked and deranged to the point of insentience. [[spoiler: As a {{Wendigo}}, Hannah Washington doesn't need clothes to protect herself from the cold, and unlike the rest of the pack, dresses only in a pair of black panties - marking her out as the most violent and fearsome of all the Wendigos at Blackwood Pines. Of course, given how her condition has [[LeanAndMean distorted her physiology]] beyond all secondary sexual characteristics, it's impossible to tell that the monster is actually female until you notice Hannah's distinctive butterfly tattoo.]]
[[/folder]]

[[folder: Web Video]]
* ''WebVideo/PotterPuppetPals'': PlayedForLaughs with Dumbledore, a deranged {{Cloudcuckoolander}} who strips down for any reason or none at all and especially enjoys streaking.
-->'''Dumbledore''': ''[[CatchPhrase Naked time!]]''
* ''WebVideo/UnusAnnus:'' The video "Hunting Hee Hoo" was a {{Mockumentary}} in which Mark lost his mind and became a cryptid. He spent much of the video running through the wilderness naked.
* One of the most common news stories featured on ''WebVideo/WhatTheFuckIsWrongWithYou'' involves someone appearing naked or half-naked in public and doing something spectacularly irrational. Sometimes, alcohol, drugs or mental illness will be involved, but more often than not, no explanation for the nudity will emerge at all - much to Nash and Tara's exasperation. For good measure, this often segues into the classic "[[FullFrontalAssault Naked Rampage]]."
[[/folder]]

[[folder: Western Animation]]
* In the ''WesternAnimation/{{Daria}}'' episode "The Teachings of Don Jake", Jake, Helen and Quinn all eat the poisonous berries and begin hallucinating - during which, Jake strips down to his underwear.
* ''WesternAnimation/FostersHomeForImaginaryFriends'': Mac goes into a frenzy whenever he eats candy. In both episodes where his condition is triggered, he removes his clothes and runs around the city while screaming for more sugar.
* In ''WesternAnimation/{{Futurama}}'', Professor Farnsworth is senile and often walks around naked, shirtless, wearing only his lab coat, or other variations.
* ''WesternAnimation/KingOfTheHill'': Dale is tasked with getting a raccoon out of Hank's house after it goes underneath. Dale ends up scratched by the raccoon, leading to fears he might have rabies. Throughout the episode, he goes animalistic and insane (not helped by feeding himself via [[MushroomSamba mushrooms he's found]]). And towards the end, he's only wearing a hat, his sunglasses, and his underwear.
* In the finale of the ''WesternAnimation/RickAndMorty'' episode "Rixty Minutes," the alternate Jerry Smith ends up suffering a meltdown that begins with him stripping down to his underwear; by the time the Smiths catch up with the news report, he's already shaved off a huge chunk of his hair, tried to cut off his toe and eat it, been resuscitated by the medics, stolen a mobility scooter and led the police on a LowSpeedChase across town.
* In ''WesternAnimation/SupermanTheAnimatedSeries'', as John Corben goes mad from the SenseLossSadness of his Metallo body, he starts ripping off his clothes... along with his human-looking skin.
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[[folder: Real Life]]
* People high on PCP often disrobe because they feel very hot, even if it's in the dead of winter. Police officers know that if they come into contact with someone who is acting deranged and is naked, they'd better call for backup because restraining someone high on PCP takes several people working together.
* People in the later stages of hypothermia can become disoriented and will sometimes remove their clothing, believing that they're overheating instead of freezing to death.
* An infamous case of this occurred to Jason Russell, American activist best known as the organizer of the Kony 2012 campaign. During this campaign, he was forced to deal with constant backlash from the media and eventually couldn't handle it anymore, suffering a mental breakdown that featured him stripping naked in public. What's worse, the same media then reported on the incident, often blowing it out of proportion (among other things alleging he was also masturbating, which didn't happen). Luckily, it seems to have been a one-off thing, as Russell has recovered after a few weeks and seems to have remained healthy ever since.
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