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Added a YMMV impression of mine.

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Some portrayals go into the direction of ScareEmStraight, especially when aimed at children. Literally, who wouldn't want to brush their teeth every day to keep those scary little imps with their mining stuff away?
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* ''Vom Jörg, der Zahnweh hatte'' (German for "About George, Who Had a Toothache") is a German children's book about a boy who doesn't brush his teeth once and promptly gets caries. The caries is brought by a single, utterly ugly, green-skinned imp named the "Toothache Imp" that is a CardCarryingVillain and AxCrazy towards Jörg's teeth. And carries a pickaxe.
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* ''VideoGame/ProjectRemedium'' is an FPS where you're a nanobot shooting virus infections inside a human body, with several gigantic germs as enemies.

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* ''VideoGame/ProjectRemedium'' is an FPS where you're a nanobot shooting virus infections inside a human body, with several gigantic germs as recurring enemies.
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* ''VideoGame/ProjectRemedium'' is an FPS where you're a white blood cell shooting virus infections inside a human body, with several gigantic germs as enemies.

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* ''VideoGame/ProjectRemedium'' is an FPS where you're a white blood cell nanobot shooting virus infections inside a human body, with several gigantic germs as enemies.

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[[folder:Card Games]]
* ''TabletopGame/HealingBlade'': [[https://cf.geekdo-images.com/CSX5KBsDA2j9c7GoLbda-g__original/img/Gz4SEpcV0PMOOfh7NZ__B73Zick=/0x0/filters:format(jpeg)/pic4252133.jpg The Lords of Pestilence and Creatures of Disease]] are extremely large, scaly, dragon-like fang=bearers where they don't look like SuccubiAndInccubi or TheUndead.
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[[quoteright:350:https://static.tvtropes.org/pmwiki/pub/images/monstrousgermssuggestion2.png]]

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%% Image selected per Image Pickin' thread: https://tvtropes.org/pmwiki/posts.php?discussion=1552020950091764700
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[[quoteright:203:[[WebAnimation/GermWars https://static.tvtropes.org/pmwiki/pub/images/hqdefault_7.png]]]]
[[caption-width-right:203:[[https://www.youtube.com/watch?v=O5PwLAZNnKc "Remember, troops: Fight dirty! Hehehehe... get it? We're germs."]]]]

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[[quoteright:203:[[WebAnimation/GermWars https://static.%% Image selected per Image Pickin' thread: https://tvtropes.org/pmwiki/posts.php?discussion=16715866010.25753000
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[[caption-width-right:203:[[https://www.youtube.com/watch?v=O5PwLAZNnKc "Remember, troops: Fight dirty! Hehehehe... get it? We're germs."]]]]
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* ''VideoGame/ProjectRemedium'' is an FPS where you're a white blood cell shooting enemy germs inside a human body, with several gigantic germs as enemies.

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* ''VideoGame/ProjectRemedium'' is an FPS where you're a white blood cell shooting enemy germs virus infections inside a human body, with several gigantic germs as enemies.
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[[folder:Gamebooks]]
* ''Literature/IntoTheJawsOfDoom'': The Hall of Incredible Science has a biology display where you might get attacked by a germ sample in a petri dish, which multiplies itself repeatedly until it's as large as the entire hall. Running into the germ monster is a guaranteed Game Over - every choice you make after that (fight it, flee from it, try to trick it, use an item...) ends with the germ swallowing you alive.
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* ''VideoGame/ProjectRemedium'' is an FPS where you're a white blood cell shooting enemy germs inside a human body, with several gigantic germs as enemies.
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* ''Series/DoctorWho'': The evil space virus in the episode "The Invisible Enemy" looks like the front end of a lobster. At first it is microscopic size and clones of the Doctor and Leela are shrunk to microscopic size to fight it. Then, after they escape and are enlarged to their proper size the virus follows them and is enlarged as well.

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* ''Series/DoctorWho'': The evil space virus in the episode "The "[[Recap/DoctorWhoS15E2TheInvisibleEnemy The Invisible Enemy" Enemy]]" looks like the front end of a lobster. At first it is microscopic size and clones of the Doctor and Leela are shrunk to microscopic size to fight it. Then, after they escape and are enlarged to their proper size the virus follows them and is enlarged as well.
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* ''Manga/CellsAtWork'' is about AnthropomorphicPersonification applied to the human body at the cellular level. While the body cells all look human, bacteria are depicted more like monstrous, but humanoid aliens. Their designs are somewhat accurate, though, such as ''Staphylococcus'' bacteria having a skirt looking like a bunch of grapes. Viruses, on the other hand, are depicted as looking like hats that attach themselves to cells and turn them into basically zombies (as is seen in the influenza arc). The larger parasitic organisms look like exaggerated versions of the real parasites, and as the series continues, the pathogens become more monstrous in appearance. The DarkerAndEdgier {{spinoff}} ''Manga/CellsAtWorkCodeBlack'' continues with this tradition - gonorrhea is depicted as a tentacle monster, and a deadly strain of Streptococcus is depicted as a swarm of ''[[TabletopGame/Warhammer40000 Hormagaunt]]''-like beasts.

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* ''Manga/CellsAtWork'' is about AnthropomorphicPersonification applied to the human body at the cellular level. While the body cells all look human, bacteria are depicted more like monstrous, but humanoid aliens. Their designs are somewhat accurate, though, such as ''Staphylococcus'' bacteria having a skirt looking like a bunch of grapes. Though they're also depicted as being about the same size as the human cells or in some cases much larger, as depicting them at a realistic scale would mean they'd be dramatically smaller than the main characters and consequently wouldn't look very threatening. Viruses, on the other hand, are depicted as looking like hats that attach themselves to cells and turn them into basically zombies (as is seen in the influenza arc). The larger parasitic organisms look like exaggerated versions of the real parasites, and as the series continues, the pathogens become more monstrous in appearance. The DarkerAndEdgier {{spinoff}} ''Manga/CellsAtWorkCodeBlack'' continues with this tradition - gonorrhea is depicted as a tentacle monster, and a deadly strain of Streptococcus is depicted as a swarm of ''[[TabletopGame/Warhammer40000 Hormagaunt]]''-like beasts.
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-->--'''Staph Sargent''', "Protect, Don't Infect"

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-->--'''Staph -->-- '''Staph Sargent''', "Protect, Don't Infect"
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[[folder:Pinball]]
* ''Pinball/WeirdAlsMuseumOfNaturalHilarity'': The "Germs" mode seen in the launch trailer pits the player against red and blue cartoon germs that look like Al's head.
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Bacteria, viruses and other pathogens -- invisible little organisms that make our lives miserable by causing diseases. Before the invention of microscopes, we did not know what they looked like. Now we know that both [[https://images.fineartamerica.com/images/artworkimages/mediumlarge/1/virus-shapes-illustration-monica-schroeder.jpg viruses]] and [[https://qph.ec.quoracdn.net/main-qimg-c2a164aea96f79769f299353e15ccacb-c bacteria]] can have various geometrical forms that look [[StarfishAliens vastly different]] from multicellular organisms.

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Bacteria, viruses and other pathogens -- invisible little organisms that make our lives miserable by causing diseases. Before the invention of microscopes, we did not know what they looked like. Now we know that both [[https://images.fineartamerica.com/images/artworkimages/mediumlarge/1/virus-shapes-illustration-monica-schroeder.jpg viruses]] and [[https://qph.ec.quoracdn.net/main-qimg-c2a164aea96f79769f299353e15ccacb-c bacteria]] bacteria can have various geometrical forms that look [[StarfishAliens vastly different]] from multicellular organisms.
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[[folder:Western Animation]]

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[[folder:Western Animation]][[folder:Real Life]]
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[[folder:Western Animation]]
*Bacteriophages are known for their distinctive spider-like appearance, with their "head" rising above their "legs". Despite their monstrous appearance, bacteriophages are harmless to humans as they target bacteria - their complex structure was evolved to get past defensive mechanisms specific to bacteria by acting as syringes to inject genetic information in species-specific receptors.
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* The main character of '' Manga/{{Moyashimon}}'' has the ability to see microbes. From his perspective they look like cute little anthropomorphic creatures even though he is aware that microbes don't actually look like that.

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* ''Manga/CellsAtWork'' is about AnthropomorphicPersonification applied to the human body at the cellular level. While the body cells all look human, bacteria are depicted more like monstrous, but humanoid aliens. Their designs is somewhat accurate, though, such as ''Staphylococcus'' bacteria having a skirt looking like a bunch of grapes. Viruses, on the other hand, are depicted as looking like hats that attach themselves to cells and turn them into basically zombies (as is seen in the influenza arc). The larger parasitic organisms look like exaggerated versions of the real parasites, and as the series continues, the pathogens become more monstrous in appearance. The DarkerAndEdgier {{spinoff}} ''Manga/CellsAtWorkCodeBlack'' continues with this tradition - gonorrhea is depicted as a tentacle monster, and a deadly strain of Streptococcus is depicted as a swarm of [[TabletopGame/Warhammer40000 Hormagaunt]]-like beasts.

to:

* ''Manga/CellsAtWork'' is about AnthropomorphicPersonification applied to the human body at the cellular level. While the body cells all look human, bacteria are depicted more like monstrous, but humanoid aliens. Their designs is are somewhat accurate, though, such as ''Staphylococcus'' bacteria having a skirt looking like a bunch of grapes. Viruses, on the other hand, are depicted as looking like hats that attach themselves to cells and turn them into basically zombies (as is seen in the influenza arc). The larger parasitic organisms look like exaggerated versions of the real parasites, and as the series continues, the pathogens become more monstrous in appearance. The DarkerAndEdgier {{spinoff}} ''Manga/CellsAtWorkCodeBlack'' continues with this tradition - gonorrhea is depicted as a tentacle monster, and a deadly strain of Streptococcus is depicted as a swarm of [[TabletopGame/Warhammer40000 Hormagaunt]]-like ''[[TabletopGame/Warhammer40000 Hormagaunt]]''-like beasts.



* In the Creator/DonRosa [[ComicBook/DisneyDucksComicUniverse Scrooge McDuck]] comic "The Incredible Shrinking Tightwad", Scrooge and Donald are shrunk down to microscopic size due to the effects of a malfunctioning ShrinkRay, and are menaced by a horde of microbes, some of which have eyes, mouths or crab-like pincers.

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* ''ComicBook/DisneyDucksComicUniverse'': In the Creator/DonRosa [[ComicBook/DisneyDucksComicUniverse Scrooge McDuck]] "[=Scrooge McDuck=]" comic "The Incredible Shrinking Tightwad", Scrooge and Donald are shrunk down to microscopic size due to the effects of a malfunctioning ShrinkRay, and are menaced by a horde of microbes, some of which have eyes, mouths or crab-like pincers.



* ''Franchise/GreenLantern'': Before starting the ComicBook/SinestroCorpsWar, Kyle Rayner's mother died by a strange and incurable disease, which makes him depressed, specially because he couldn't be there when she died. When he's kidnapped by Sinestro, he revealed that that the sentient virus Despotellis was responsible for the death of his mother, which also was part of Sinestro Corps. Broken and overcome with fear, Kyle is sent to the Central Battery of Qward where he is possessed by Parallax, becoming its new host. Despotellis is depicted as similar in shape to a bacteriophage, but with tentacle-like appendages.
* Generally averted in Marvel Comics with all the face to face shrinking heroes get with microorganisms but a sentient virus from the microverse in an arc of Wolverine is depicted as having a whole lot of eyes and tentacles.

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* ''Franchise/GreenLantern'': Before starting the ComicBook/SinestroCorpsWar, beginning of ''ComicBook/SinestroCorpsWar'', Kyle Rayner's mother died by a strange and incurable disease, which makes him depressed, specially because he couldn't be there when she died. When he's kidnapped by Sinestro, he revealed that that the sentient virus Despotellis was responsible for the death of his mother, which also was part of Sinestro Corps. Broken and overcome with fear, Kyle is sent to the Central Battery of Qward where he is possessed by Parallax, becoming its new host. Despotellis is depicted as similar in shape to a bacteriophage, but with tentacle-like appendages.
* Generally averted in Marvel Comics ''Franchise/MarvelUniverse'' with all the face to face shrinking heroes get with microorganisms but a sentient virus from the microverse in an arc of Wolverine is depicted as having a whole lot of eyes and tentacles.tentacles.
* In ''Franchise/{{Superman}}'' storyline ''ComicBook/TheUnknownSupergirl'', the bacteria fought by ComicBook/{{Supergirl}} in Mr. Malverne's bloodstream look like weird multi-limbed grey worms with furry heads, six eyes, antennae and beaks.



* In ''Film/OsmosisJones'', germs are portrayed as humanoid creatures with mismatched body parts and often reptilian features. The BigBad Thrax is a red-skinned humanoid with tentacle-like dreadlocks and a large burning claw on one of his hands. The SeekerWhiteBloodCells who fight against them look much more human-like apart from their blue skin. This trope is PlayedWith, however, in that while most germs in the movie are criminals of various sorts, germs and body cells can be seen hanging around with each other in some of the more run-down districts, like The Liver.

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* In ''Film/OsmosisJones'', germs are portrayed as humanoid creatures with mismatched body parts and often reptilian features. The BigBad Thrax [[BigBad Thrax]] is a red-skinned humanoid with tentacle-like dreadlocks and a large burning claw on one of his hands. The SeekerWhiteBloodCells who fight against them look much more human-like apart from their blue skin. This trope is PlayedWith, however, in that while most germs in the movie are criminals of various sorts, germs and body cells can be seen hanging around with each other in some of the more run-down districts, like The Liver.
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* ''Manga/CellsAtWork'' is about AnthropomorphicPersonification applied to the human body at the cellular level. While the body cells all look human, bacteria are depicted more like monstrous, but humanoid aliens. Their designs is somewhat accurate, though, such as ''Staphylococcus'' bacteria having a skirt looking like a bunch of grapes. Viruses, on the other hand, are depicted as looking like hats that attach themselves to cells and turn them into basically zombies (as is seen in the influenza arc). The larger parasitic organisms look like exaggerated versions of the real parasites, and as the series continues, the pathogens become more monstrous in appearance. The DarkerAndEdgier {{spinoff}} ''Manga/CellsAtWorkCodeBlack'' continues with this tradition - gonorrhea is depicted as a tentacle monster, and a deadly strain of Streptococcus is depicted as a swarm of hormigaunts.

to:

* ''Manga/CellsAtWork'' is about AnthropomorphicPersonification applied to the human body at the cellular level. While the body cells all look human, bacteria are depicted more like monstrous, but humanoid aliens. Their designs is somewhat accurate, though, such as ''Staphylococcus'' bacteria having a skirt looking like a bunch of grapes. Viruses, on the other hand, are depicted as looking like hats that attach themselves to cells and turn them into basically zombies (as is seen in the influenza arc). The larger parasitic organisms look like exaggerated versions of the real parasites, and as the series continues, the pathogens become more monstrous in appearance. The DarkerAndEdgier {{spinoff}} ''Manga/CellsAtWorkCodeBlack'' continues with this tradition - gonorrhea is depicted as a tentacle monster, and a deadly strain of Streptococcus is depicted as a swarm of hormigaunts.[[TabletopGame/Warhammer40000 Hormagaunt]]-like beasts.
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* ''WesternAnimation/HowToCatchACold'': Occasionally, germs are seen as a cloud of red dust.
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* Subverted in an arc of ''Webcomic/{{Vexxarr}}'' where a couple [[http://www.vexxarr.com/archive.php?seldate=032020 COVID-19 viruses]] try to cope with the titular character's BizarreAlienBiology. You almost feel sorry for them.
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[[folder:Music Videos]]
* In the ''Music/PreschoolPopstars'' song "Wash Your Hands", the musical features germs as multicoloured blobs with faces and ganglia.
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* ''Website/ScrubClub'' has green, bipedal, lumpy germs that act like cheesy villains.
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* On ''Series/GoodEats'', bacteria that lead to food spoilage (and food poisoning), foul-tasting beer, etc. were portrayed as (variously) ugly sock puppets (in contrast to the cute yeast puppets), shaggy plush things, and reptilian finger puppets.

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* ''Manga/CellsAtWork'':
** The manga and anime are about AnthropomorphicPersonification applied to the human body at the cellular level. While the body cells all look human, bacterias are depicted more like monstrous, but humanoid aliens. Their designs is somewhat accurate, though, such as ''Staphylococcus'' bacteria having a skirt looking like a bunch of grapes. Viruses, on the other hand, are depicted as hats that attach themselves to cells and turn them to to basically zombies. The larger parasitic organisms look like exaggerated versions of the real parasites, and as the series continues, the pathogens become more monstrous in appearance.
** ''Cells at Work!'''s {{spinoff}} ''Manga/CellsAtWorkCodeBlack'' continues with this tradition; gonorrhea is depicted as a tentacle monster, and a deadly strain of Streptococcus is depicted as a swarm of hormigaunts.

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* ''Manga/CellsAtWork'':
** The manga and anime are
''Manga/CellsAtWork'' is about AnthropomorphicPersonification applied to the human body at the cellular level. While the body cells all look human, bacterias bacteria are depicted more like monstrous, but humanoid aliens. Their designs is somewhat accurate, though, such as ''Staphylococcus'' bacteria having a skirt looking like a bunch of grapes. Viruses, on the other hand, are depicted as looking like hats that attach themselves to cells and turn them to to into basically zombies. zombies (as is seen in the influenza arc). The larger parasitic organisms look like exaggerated versions of the real parasites, and as the series continues, the pathogens become more monstrous in appearance.
** ''Cells at Work!'''s
appearance. The DarkerAndEdgier {{spinoff}} ''Manga/CellsAtWorkCodeBlack'' continues with this tradition; tradition - gonorrhea is depicted as a tentacle monster, and a deadly strain of Streptococcus is depicted as a swarm of hormigaunts.
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* In ''Film/OsmosisJones'', germs are portrayed as humanoid creatures with mismatched body parts and often reptilian features. The BigBad Thrax is a red-skinned humanoid with tentacle-like dreadlocks and a large burning claw on one of his hands. The SeekerWhiteBloodCells who fight against them look much more human-like apart from their blue skin.

to:

* In ''Film/OsmosisJones'', germs are portrayed as humanoid creatures with mismatched body parts and often reptilian features. The BigBad Thrax is a red-skinned humanoid with tentacle-like dreadlocks and a large burning claw on one of his hands. The SeekerWhiteBloodCells who fight against them look much more human-like apart from their blue skin. This trope is PlayedWith, however, in that while most germs in the movie are criminals of various sorts, germs and body cells can be seen hanging around with each other in some of the more run-down districts, like The Liver.



* ''VideoGame/DrMario'' has the ever present trio of viruses, one blue, one red and one yellow {{Cephalothorax}} creature with eyes, mouth, hands and feet. ''Dr. Luigi'' introduces cyan and magenta variants.

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* ''VideoGame/DrMario'' has the ever present trio of viruses, one blue, one red and one yellow {{Cephalothorax}} creature with eyes, mouth, hands and feet. ''Dr. Luigi'' introduces cyan and magenta variants.variants, and Dr. Mario World introduces the green and purple ones.
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** The manga and anime are about AnthropomorphicPersonification applied to the human body at the cellular level. While the body cells all look human, bacterias are depicted more like monstrous, but humanoid aliens. Their designs is somewhat accurate, though, such as ''Staphylococcus'' bacteria having a skirt looking like a bunch of grapes. Viruses, on the other hand, are depicted as hats that attach themselves to cells and turn them to to basically zombies.

to:

** The manga and anime are about AnthropomorphicPersonification applied to the human body at the cellular level. While the body cells all look human, bacterias are depicted more like monstrous, but humanoid aliens. Their designs is somewhat accurate, though, such as ''Staphylococcus'' bacteria having a skirt looking like a bunch of grapes. Viruses, on the other hand, are depicted as hats that attach themselves to cells and turn them to to basically zombies. The larger parasitic organisms look like exaggerated versions of the real parasites, and as the series continues, the pathogens become more monstrous in appearance.
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Moving to English translation title


** ''Cells at Work!'''s {{spinoff}} ''Manga/CellsAtWorkBlack'' continues with this tradition; gonorrhea is depicted as a tentacle monster, and a deadly strain of Strepptococcus is depicted as a swarm of hormigaunts.

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** ''Cells at Work!'''s {{spinoff}} ''Manga/CellsAtWorkBlack'' ''Manga/CellsAtWorkCodeBlack'' continues with this tradition; gonorrhea is depicted as a tentacle monster, and a deadly strain of Strepptococcus Streptococcus is depicted as a swarm of hormigaunts.
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Almost always present as major antagonists in any case of AnthropomorphizedAnatomy.
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** ''Cells at Work!'''s {{spinoff}} ''Manga/CellsAtWorkBlack'' continues with this tradition; gonorrhea is depicted as a tentacle monster.

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** ''Cells at Work!'''s {{spinoff}} ''Manga/CellsAtWorkBlack'' continues with this tradition; gonorrhea is depicted as a tentacle monster.monster, and a deadly strain of Strepptococcus is depicted as a swarm of hormigaunts.

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