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* ''WebVideo/ImAutisticNowWhat'' is a series of YouTube videos hosted by an Autistic housewife and mother named Megan, consisting both of stories about her own lived experiences with Autism and [[ReactionVideo her reactions to other Autism-related content]].
* Creator/PaigeLayle is an Autistic vlogger who does various Autism-related content on YouTube and TikTok.
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* ''VideoGame/{{Amy}}'': The titular character is an eight-year-old autistic girl with psychic powers.

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* ''VideoGame/{{Amy}}'': ''VideoGame/{{Amy|2012}}'': The titular character is an eight-year-old autistic girl with psychic powers.
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* The ''VideoGame/{{Omori}}'' fan fic ''FanFic/TimeToDisinfect'' depicts Mari as being autistic, as is the writer who is drawing on their own experiences with autism.

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* The ''VideoGame/{{Omori}}'' fan fic ''FanFic/TimeToDisinfect'' depicts Mari ''FanFic/TimeToDisinfect'': [[VideoGame/{{Omori}} Mari]] is depicted as being autistic, as is the writer who is drawing on their own experiences with autism.

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* ''Fanfic/TokimekiPokeLiveAndTwinbee'': Elesis/Ellie is mentioned as being a high-functioning autistic on her Toyhou.se bio even though it hasn't been brought up in a story yet.
* ''Fanfic/TotalDramaLegacy'' and its sequel, ''Total Drama Worldwide'', give us Serena, the daughter of Harold and Leshawna. She's confirmed to be autistic in the ''Worldwide'' episode "Nuclear Winners". Her special interest is anime and she [[OccidentalOtaku constantly brings it up]].



* ''Fanfic/TotalDramaLegacy'' and its sequel, ''Total Drama Worldwide'', give us Serena, the daughter of Harold and Leshawna. She's confirmed to be autistic in the ''Worldwide'' episode "Nuclear Winners". Her special interest is anime and she [[OccidentalOtaku constantly brings it up]].
* ''Fanfic/TokimekiPokeLiveAndTwinbee'': Elesis/Ellie is mentioned as being a high-functioning autistic on her Toyhou.se bio even though it hasn't been brought up in a story yet.
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* The ''VideoGame/{{Omori}}'' fan fic ''FanFic/TimeToDisinfect'' depicts Mari as being autistic, as is the writer who is drawing on their own experiences with autism.
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* ''Literature/VirtusDraconis'' centers around an autistic dragon and his comrades as they struggle against a princess's war, brought about by societal changes she disagrees with. On the other side of the argument, an alligator regent, strongly implied to be autistic as well, deals with questions surrounding his future allegiance and whether he wants to continue following his princess.
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* ''Literature/SlugDaysStories'' is a series of realistic children's books about a girl with Autism Spectrum Disorder.
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* Dina Saruyama in ''Webcomic/DumbingOfAge'' is confirmed by author David Willis to have undiagnosed Asperger syndrome. Joyce is waiting for a diagnosis, and during the resultant discussion, Dina says she ''can't'' get one (every specialist her parents have spoken to says her language difficulties are due to being a second-generation immigrant ''which she's not''), and Dorothy and Sarah both suggest the other might be.

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* Dina Saruyama in ''Webcomic/DumbingOfAge'' is confirmed by author David Willis to have undiagnosed Asperger syndrome. Joyce is waiting for a diagnosis, and during but everyone agrees it makes perfect sense. During the resultant discussion, Dina says she ''can't'' get one (every one; every specialist her parents have spoken to says her language difficulties are due to being a second-generation immigrant immigrant, ''which she's not''), and Dorothy and Sarah both suggest the other might be.not''.
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* Dina Saruyama in ''Webcomic/DumbingOfAge'' is confirmed by author David Willis to have undiagnosed Asperger syndrome.

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* Dina Saruyama in ''Webcomic/DumbingOfAge'' is confirmed by author David Willis to have undiagnosed Asperger syndrome. Joyce is waiting for a diagnosis, and during the resultant discussion, Dina says she ''can't'' get one (every specialist her parents have spoken to says her language difficulties are due to being a second-generation immigrant ''which she's not''), and Dorothy and Sarah both suggest the other might be.
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* In ''Literature/{{Rubbernecker}}'', one of the main characters is a medical student with Asperger's.
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* ''LetsPlay/WitchCraftSMP'': Pris lacks a filter in some situations, doesn't understand subtlety, and is overall considered an oddball, e.g. for giving weird compliments. She is confirmed to be autistic by her content creator counterpart, [[DisabledCharacterDisabledActor who is also autistic]].

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* ''LetsPlay/WitchCraftSMP'': ''WebVideo/WitchCraftSMP'': Pris lacks a filter in some situations, doesn't understand subtlety, and is overall considered an oddball, e.g. for giving weird compliments. She is confirmed to be autistic by her content creator counterpart, [[DisabledCharacterDisabledActor who is also autistic]].
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* In ''Literature/TheManyMysteriesOfTheFinkelFamily'', the protagonist and most of her family are autistic or otherwise neurodivergent.
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* ''Film/Music2021'': The directorial debut of Music/{{Sia}}. The movie is about a recently sober drug dealer named Kazu "Zu" Gamble finding herself taking custody of her younger half-sister, a non-verbal autistic teenage girl named Music, when their grandmother suddenly dies. The film is heavily controversial for [[WTHCastingAgency casting a neurotypical actress as the nonverbal autistic Music]], its [[HollywoodAutism caricature-like ableist stereotypes about autism]], its general ignorance about the condition, and advocating the use of the prone restraint to stop an autistic person having a meltdown despite the fact that it has traumatized, injured, and killed several autistic people in real life.

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* ''Film/Music2021'': The directorial debut of Music/{{Sia}}. The movie is about a recently sober drug dealer named Kazu "Zu" Gamble finding herself taking custody of her younger half-sister, a non-verbal autistic teenage girl named Music, when their grandmother suddenly dies. The film is heavily controversial for [[WTHCastingAgency [[QuestionableCasting casting a neurotypical actress as the nonverbal autistic Music]], its [[HollywoodAutism caricature-like ableist stereotypes about autism]], its general ignorance about the condition, and advocating the use of the prone restraint to stop an autistic person having a meltdown despite the fact that it has traumatized, injured, and killed several autistic people in real life.
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* ''Series/{{Astrid}}'': French-Belgian crime drama in which the titular Astrid Nielsen, an autistic librarian, and CowboyCop Raphaëlle Coste investigate murders. One of the co-writers is autistic.

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* ''Series/{{Astrid}}'': French-Belgian crime drama in which the titular eponymous Astrid Nielsen, an autistic librarian, and CowboyCop Raphaëlle Coste investigate murders. One of the co-writers is autistic.autistic, and the series extensively features Astrid attending an autism support group whose members often consult on cases.
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* Marcy Wu from ''WesternAnimation/{{Amphibia}}'' shows signs of having both autism and ADHD. She's obsessed with anime, video games, and tabletop games, extremely clumsy, has excessive knowledge and a desire to learn more, has a short attention span, and has a tendency to "get caught in the zone" (hyperfocus). She even says she has trouble looking people in the eye sometimes. [[spoiler:She also has moments of being InnocentlyInsensitive, which is common amongst the autistic community.]] When originally asked about it in a Reddit AMA, series creator Matt Braly stated that [[https://drive.google.com/file/u/1/d/1h04GAjYd10FRomX6aG6RBCzaB7ywo-9m/view?usp=drivesdk Marcy wasn’t created with her having autism in mind, but also that there’s still "a lot to learn about her, even on our end"]], implying that [[AscendedFanon her being neurodivergent could eventually become canon later on if it suits the show's story]]. On June 15, 2022, the ''Amphibia'' crew confirmed via Twitter [[https://twitter.com/scisetstarlight/status/1536939409496342528 that Marcy does indeed have autism,]] making her the first canonically autistic character in any Disney Television Animation series, and also the second canonically neurodivergent Disney TVA character, following Luz Noceda (who also has ADHD) from ''WesternAnimation/TheOwlHouse''.
* ''WesternAnimation/{{Archer}}'': Sterling Archer questions if he's on the spectrum throughout the series, as he finds himself being the only one to identify weapons at a glance, keep track of bullet counts, and other such things when in battles. It's never portrayed negatively, more along the lines of "[[ThisExplainsSoMuch Huh. That would explain a lot]]."

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* [[Characters/AmphibiaMarcyWu Marcy Wu Wu]] from ''WesternAnimation/{{Amphibia}}'' shows signs of having both autism and ADHD. She's obsessed with anime, video games, and tabletop games, extremely clumsy, has excessive knowledge and a desire to learn more, has a short attention span, and has a tendency to "get caught in the zone" (hyperfocus). She even says she has trouble looking people in the eye sometimes. [[spoiler:She also has moments of being InnocentlyInsensitive, which is common amongst the autistic community.]] When originally asked about it in a Reddit AMA, series creator Matt Braly stated that [[https://drive.google.com/file/u/1/d/1h04GAjYd10FRomX6aG6RBCzaB7ywo-9m/view?usp=drivesdk Marcy wasn’t created with her having autism in mind, but also that there’s still "a lot to learn about her, even on our end"]], implying that [[AscendedFanon her being neurodivergent could eventually become canon later on if it suits the show's story]]. On June 15, 2022, the ''Amphibia'' crew confirmed via Twitter [[https://twitter.com/scisetstarlight/status/1536939409496342528 that Marcy does indeed have autism,]] making her the first canonically autistic character in any Disney Television Animation series, and also the second canonically neurodivergent Disney TVA character, following [[Characters/TheOwlHouseLuzNoceda Luz Noceda Noceda]] (who also has ADHD) from ''WesternAnimation/TheOwlHouse''.
* ''WesternAnimation/{{Archer}}'': [[Characters/ArcherSterlingArcher Sterling Archer Archer]] questions if he's on the spectrum throughout the series, as he finds himself being the only one to identify weapons at a glance, keep track of bullet counts, and other such things when in battles. It's never portrayed negatively, more along the lines of "[[ThisExplainsSoMuch Huh. That would explain a lot]]."



* Though not definitively confirmed as such, Tina Belcher of ''WesternAnimation/BobsBurgers'' is implied to be autistic as she speaks in a CreepyMonotone, expresses distress through long groans, has NoSocialSkills and awkward body language, and can get extremely obsessive when it comes to horses or her crush Jimmy Jr.. Louise even says she's probably autistic in the first episode, and when Bob tries to deny it, Louise dumps a bunch of straws onto the floor and tells Tina to count them to which she replies "three".

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* Though not definitively confirmed as such, [[Characters/BobsBurgersTinaBelcher Tina Belcher Belcher]] of ''WesternAnimation/BobsBurgers'' is implied to be autistic as she speaks in a CreepyMonotone, expresses distress through long groans, has NoSocialSkills and awkward body language, and can get extremely obsessive when it comes to horses or her crush Jimmy Jr.. Louise even says she's probably autistic in the first episode, and when Bob tries to deny it, Louise dumps a bunch of straws onto the floor and tells Tina to count them to which she replies "three".



* ''WesternAnimation/RickAndMorty'': One of the two main characters, Morty's grandfather Rick, mentions possibly being autistic while playing ''VideoGame/{{Minecraft}}''.

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* ''WesternAnimation/RickAndMorty'': One of the two main characters, Morty's [[Characters/RickAndMortyMortySmith Morty Smith's]] grandfather Rick, [[Characters/RickAndMortyRickSanchez Rick Sanchez]], mentions possibly being autistic while playing ''VideoGame/{{Minecraft}}''.



* ''WesternAnimation/SheRaAndThePrincessesOfPower'': After the show ended, the showrunners confirmed that Entrapta is autistic. Entrapta has a variety of quirks. As she says, she's "Not good with people, but [she's] good with tech." She can be outright obsessive when it comes to understanding First Ones tech and doesn't seem to understand or care about consequences outside of the tech itself.[[note]]When She-Ra got infected by a corrupted disc, Entrapta was gleeful even when being attacked because it gave her something new to research.[[/note]] She has trouble reading social cues, to the point that she needed to ask whether Mermista was angry after Mermista got through yelling at her. She doesn't seem to have a concept of morality and had to be outright reminded of which side of the conflict she was on (and why the enemies of that side should be considered ''her'' enemies). That said, she's fiercely loyal to those she considers her friends, and once she realizes that there's been a failure of communication, she does her best to resolve the issue, either via explaining herself better or seeking further clarification. [[ArsonMurderAndJaywalking And she won't eat food if it isn't tiny.]]

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* ''WesternAnimation/SheRaAndThePrincessesOfPower'': After the show ended, the showrunners confirmed that Entrapta [[Characters/SheRaAndThePrincessesOfPowerEntrapta Entrapta]] is autistic. Entrapta has a variety of quirks. As she says, she's "Not good with people, but [she's] good with tech." She can be outright obsessive when it comes to understanding First Ones tech and doesn't seem to understand or care about consequences outside of the tech itself.[[note]]When She-Ra got infected by a corrupted disc, Entrapta was gleeful even when being attacked because it gave her something new to research.[[/note]] She has trouble reading social cues, to the point that she needed to ask whether Mermista was angry after Mermista got through yelling at her. She doesn't seem to have a concept of morality and had to be outright reminded of which side of the conflict she was on (and why the enemies of that side should be considered ''her'' enemies). That said, she's fiercely loyal to those she considers her friends, and once she realizes that there's been a failure of communication, she does her best to resolve the issue, either via explaining herself better or seeking further clarification. [[ArsonMurderAndJaywalking And she won't eat food if it isn't tiny.]]
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* In ''Literature/{{Transpecial}}'', an autistic woman is recruited to help establish communication with aliens.
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* ''WebOriginal/LoomingGaia'': [[https://loominggaia.tumblr.com/post/648509100587679744/are-there-autistic-characters-in-looming-gaia The Greys has confirmed on her Tumblr]] that Elska has autism or at least the centaur equivalent of it; she has trouble with socializing and can be rude without intending to, has issues with dealing with stress, HatesBeingTouched, and has tendency to get obsessed with things like "fighting the fog" as a child and getting revenge on the people who killed her village as an adult. Greys mentions in the same post that Jeimos and Mr. Ocean are autistic as well.

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* ''WebOriginal/LoomingGaia'': ''Literature/LoomingGaia'': [[https://loominggaia.tumblr.com/post/648509100587679744/are-there-autistic-characters-in-looming-gaia The Greys has confirmed on her Tumblr]] that Elska has autism or at least the centaur equivalent of it; she has trouble with socializing and can be rude without intending to, has issues with dealing with stress, HatesBeingTouched, and has tendency to get obsessed with things like "fighting the fog" as a child and getting revenge on the people who killed her village as an adult. Greys mentions in the same post that Jeimos and Mr. Ocean are autistic as well.
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[[folder:Web Video]]
* ''WebVideo/CafaeLatte'': One of the main characters, Nicole, is autistic (saying so in her introduction). She stims when she is in stressful situations and is extremely blunt and quick to question social rules.
** In one episode, a mother brings in her autistic son on the mistaken impression that [[ChangelingTale he is a changeling]]. Nicole enchants a rock to give him the same effect as stimming. When they come back to pick up the rock, the mother's dismissal of her son's sensory issues leads Bob to [[spoiler:curse her with those same exact sensory issues]].
[[/folder]]
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* ''WesternAnimation/ThomasAndFriendsAllEnginesGo'' introduced a child brake van character named Bruno who is on the autism spectrum. He sometimes wears steam headphones to block out loud noises, has eye contact issues, and talks slowly and in detail.

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* ''WesternAnimation/ThomasAndFriendsAllEnginesGo'' introduced a child brake van caboose character named Bruno who is on the autism spectrum. He sometimes wears steam headphones to block out loud noises, has eye contact issues, and talks slowly and in detail.
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* ''Literature/AreYouSeeingMe'' is about a young woman and her autistic twin brother going on a road trip before her brother moves into an assisted living facility.
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* ''WebOriginal/LoomingGaia'': [[https://loominggaia.tumblr.com/post/648509100587679744/are-there-autistic-characters-in-looming-gaia The Greys has confirmed on her Tumblr]] that Elska has autism or at least the centaur equivalent of it; she has trouble with socializing and can be rude without intending to, has issues with dealing with stress, HatesBeingTouched, and has tendency to get obsessed with things like "fighting the fog" as a child and getting revenge on the people who killed her village as an adult. Greys mentions in the same post that Jeimos and Mr. Ocean are autistic as well.
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* ''WebAnimation/InvestigationOfObjectNuclearity'' The protagonist Cracklin is autistic.

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* ''WebAnimation/InvestigationOfObjectNuclearity'' ''WebAnimation/InvestigationOfObjectNuclearity'': The protagonist Cracklin is autistic.
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* ''InvestigationOfObjectNuclearity'' The protagonist Cracklin is autistic.

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* ''InvestigationOfObjectNuclearity'' ''WebAnimation/InvestigationOfObjectNuclearity'' The protagonist Cracklin is autistic.
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* ''InvestigationOfObjectNuclearity'' The protagonist Cracklin is autistic.
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* Creator/TheTransformistress is known for comics with trans protagonists, with Cassandra "Cass" Iski from "The Trans Skill Tree" being both trans and autistic; in addition to directly referring to herself as such, she dislikes talking with real people because of messy misinterpretations, worries about overstimulation when her body starts transforming, and then stims with excitement when her AMAB body becomes the CatGirl she's always wanted to be.
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* ''VideoGame/ToTheMoon'': Johnny's wife River has a condition that makes it difficult for her to communicate and also makes her feel "different" from her classmates. She also has a special interest in lighthouses, even naming one "Anya". Johnny consults a psychologist to help him understand her better, and he learns about Tony Attwood's studies on the condition. Kan Gao eventually [[https://twitter.com/reives_freebird/status/1669751016584097794 confirms on his Twitter]] on the game's 10th anniversary that River is autistic.

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* ''VideoGame/ToTheMoon'': Johnny's wife River has a condition that makes it difficult for her to communicate and also makes her feel "different" from her classmates. She also has a special interest in lighthouses, even naming one "Anya". Johnny consults a psychologist to help him understand her better, and he learns about Tony Attwood's studies on the condition. Kan Gao eventually [[https://twitter.com/reives_freebird/status/1669751016584097794 confirms confirmed on his Twitter]] on the game's 10th anniversary that River is autistic.
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* ''Series/TheBridgeUS'': Main character Sonya has Asperger syndrome.
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* ''VideoGame/ToTheMoon'': Johnny's wife River has a condition that makes it difficult for her to communicate and also makes her feel "different" from her classmates. She also has a special interest in lighthouses, even naming one "Anya". Johnny consults a psychologist to help him understand her better, and he learns about Tony Attwood's studies on the condition. Kan Gao eventually [[https://twitter.com/reives_freebird/status/1669751016584097794 on his Twitter]] on the game's 10th anniversary that River is autistic.

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* ''VideoGame/ToTheMoon'': Johnny's wife River has a condition that makes it difficult for her to communicate and also makes her feel "different" from her classmates. She also has a special interest in lighthouses, even naming one "Anya". Johnny consults a psychologist to help him understand her better, and he learns about Tony Attwood's studies on the condition. Kan Gao eventually [[https://twitter.com/reives_freebird/status/1669751016584097794 confirms on his Twitter]] on the game's 10th anniversary that River is autistic.

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* ''Fanfic/{{Quiververse}}'': In ''Scars of the Quill'', it's explained that Quiver Quill's younger brother Regal Grace was autistic and communicated mostly by wailing. [[spoiler: His death due to a tragic accident provides much of the drama for Quiver's storyline.]]

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* ''Fanfic/{{Quiververse}}'': In ''Scars of the Quill'', it's explained that Quiver Quill's younger brother Regal Grace was autistic and communicated mostly by wailing. [[spoiler: His [[spoiler:His death due to a tragic accident provides much of the drama for Quiver's storyline.]]


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* ''VideoGame/ToTheMoon'': Johnny's wife River has a condition that makes it difficult for her to communicate and also makes her feel "different" from her classmates. She also has a special interest in lighthouses, even naming one "Anya". Johnny consults a psychologist to help him understand her better, and he learns about Tony Attwood's studies on the condition. Kan Gao eventually [[https://twitter.com/reives_freebird/status/1669751016584097794 on his Twitter]] on the game's 10th anniversary that River is autistic.
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* ''Literature/ApolloAutism'' has a patent agent and his wife raising two young autistic sons in TheSixties and TheSeventies. The protagonist is implied to have undiagnosed autism as well.

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* ''Literature/ApolloAutism'' has a patent agent and his wife raising two young autistic sons in TheSixties and TheSeventies. The protagonist is implied to have eventually realizes that he has undiagnosed autism as well.

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