- Game Breaker: In some games, the Vlish. They are cheap to create and cause both slow and poison status effects, making a sufficiently-leveled pack of them unbeatable even on higher difficulty levels.
- Goddamn Bats: Enemy Vlish. They swarm and cause a variety of negative status effects.
- Podlings in V have area-effect attacks that inflict negative status effects. And since different varieties inflict different effects, it can get very annoying very quickly.