Michael Emerson saying "I've been watching you for a long time, John" sounds awfully familiar.
So does the sound of a receipt being printed in a taxi cab that just so happens to be driven by Michael Emerson's character. LOST's sound effect for the "smoke monster" was derived from this sound.
Reese: "Where did you come from?" Finch: "I breached the space/time continuum. Not really." (Yes really).
In "Witness," a student of the teacher John is protecting is reading The Count of Monte Cristo as a homework assignment. Jim Caviezel played the title count in the 2002 version of the movie.
Doubles as a Whole Plot Reference. The Count of Monte Cristo is about a man who devotes his life to revenge, heedless of the cost to others—which is a pretty fair description of that episode's POI, Carl Elias.
At one point Detective Carter tells Reese that he can't keep playing God.
In episode 2.5 "Bury the Lede" Reese is given the alias "John Anderson." The surname "Anderson" is a derivative of "Son of Man"
Judging from the number of Passion Of The Christ references that have been made so far, it's likely that the list of Jesus jokes is only going to keep growing.
Alternatively, Reese just foiled a plot by the Doci.
Invisible Advertising: The amount of advertising the show gets is woefully out of proportion with how high its ratings are; it's one of the highest rated shows in the country, let alone on CBS, and yet it's rarely advertised except on the night that it airs and it's often absent from the group CBS network promotions.
The opposite was true when the show was first introduced. CBS promotions went into overdrive during the summer of 2011 to hype the show up, with POI ads outnumbering those for fellow rookie Unforgettable by about two to one. Ironically, it had the opposite effect in the ratings - the premiere dropped nearly forty percent in 18-49 from the second half of a special hourlong episode of The Big Bang Theory (5.1 to 3.1), and was outrated by all but two of CBS' other Monday-Thursday dramas. Given the pedigree and heavy marketing, this was considered a disappointing start. The only upside is that, nearly two years in, the show has stayed in the general vicinity of this number, while several other CBS shows have fallen off.
John Nolan who played Kara's employer in "Dead Reckoning" is the uncle of Jonathan Nolan.
Paul Sparks (Wilson in "Relevance") is married to Annie Parisse (Kara Stanton).
What Might Have Been: The original script for the Pilot episode revealed all of John and Jessica's backstory in that episode, and would have also included a scene where Finch provides Reese with an apartment to live in. The John/Jessica backstory was cut down and then spread out over the course of the first season, and the apartment became a birthday gift in "Many Happy Returns".
Carter's pursuit of Reese was originally intended to continue over the course of the whole first season, but she ended up joining the team mid-way through due to pressure from CBS.note Mileage Varies on whether or not it was a good move for her to join so soon.
Miscellaneous Trivia:
Jim Caviezel is ambidextrous in real life.
While on location in New York City, Jim Caviezel saw some punk beating his girlfriend and "intervened".
An incident which has caused some fans to come to the conclusion that he is John Reese.
The (stolen) black Porsche that Reese drives in "Bury the Lede" actually belongs to Jim Caviezel.
Which incidentally implies that John Reese stole Jim Caviezel's car.
Person of Interest may be the first mainstream work in history to feature a married same-sex couple, specifically the POI of "Critical" and her Damsel in Distress of a significant other.
Kara Stanton was killed off earlier than expected because Annie Parisse is already on The Following.