- Like Toy Soldiers, a call for peace in the violent feuding among rappers, which has resulted in many good rappers (Tupac Shakur, The Notorious B.I.G. and others) losing their lives and having their voices silenced forever.
- The music video is impossible to watch without tearing up, depicting Eminem and the rest of D12 waiting helplessly outside of a hospital room while doctors work desperately to revive Bugz, ultimately failing, the funeral, and various footage of him and other deceased rappers as each of them fades out one by one. Made even worse when you realize Eminem had to go through the same thing again in 2006 when Proof (who, to salt the wound further, portrayed Bugz in the video) was murdered...
- Mockingbird, a song dedicated to Em's daughter Hailie and the problems that she faces with her father and mother having marital problems and the way her father's life as a rapper has affected her.
- Beautiful, more than anything else on Relapse, is clearly a product of the years Em spent in isolation following Encore. It's a pretty devastating summary of his mindset at the time.
- Hailie's Song, or for that matter, any song that Em dedicates to his little girl is both this and heartwarming. It's clear just how much he loves her.
- Going Through Changes, about Eminem's fight with his drug addiction, and how it affects his family.
- Space Bound, about a Destructive Romance that ultimately ends in a Murder-Suicide.
- You're Never Over, Em's tribute to one of his best friends, the late D12 member Proof, who was gunned down in Detroit in 2006.
- Difficult, another song dedicated to Proof, focusing on life without him.
- I Need a Doctor, Em's tribute to Dr. Dre and his effect on his life and career. Especially at the end of the music video where Dr. Dre visits Eazy-E's grave.
- "You risked your career for me, I know it as well as you—nobody wanted to fuck with the white boy Dre, I'm crying in this booth!"
- "But I'm not giving up faith - and you ain't giving up on me! Get up Dre! I'm dying, I need you, COME BACK FOR FUCK'S SAKE!" Raw passion.
- Stan, about a Loony Fan who goes over the edge because of his obsession with Slim, and Slim finally writing back, telling him about an episode he saw on the news that made him sick, about someone who tied up his pregnant girlfriend and went off a bridge — and realizing that it was actually Stan. The song is inspired by the death of Eminem's uncle Ronnie, who took his own life in 1991.
- Love the Way You Lie, the heart-wrenching story of two people falling in love and the man's downward spiral as an abuser. The chorus really hits home if someone has been through that.
Just gonna stand there and watch me burn
But that's all right because I like the way it hurts
Just gonna stand there and here me cry
But that's all right because I love the way you lie
- When I'm Gone, a candid discussion of the Adult Fear of catastrophically failing to balance career and home life, with a chorus fit for a funeral.
- His verse on B.o.B's Airplanes (Part II)
- To elaborate, the verse (and the song overall) is about how his life could have gone if he didn't make it in the rap industry. It's not a pretty picture.
- YMMV, but Sing For The Moment has shades of this.
- Headlights is perhaps the greatest tearjerker of all of Em's songs. It is also a Crowning Moment of Heartwarming, for reasons described on that page.
I want a new life
- Nate Ruess' verses definitely don't help:
One without a cause
So I'm coming home tonight
Well, no matter what the cost
And if the plane goes down
Or if the crew can't wake me up
Well, just know that I'm alright
I was not afraid to die
- My Fault was also pretty stirring, and it comes to a peak with its ending.
- Legacy, in which Eminem discusses his traumatic childhood, and wonders why he is so 'differently wired'.
- Cleanin' Out My Closet, in which Eminem basically provides a no-holds-barred look at his Dark and Troubled Past, from his rocky parental connections to his turbulent marriage with Kim. You can't listen to it without feeling bad for Em at times, especially with the final lines:
"Remember when Ronnie died and you said you wished it was me? Well guess what, I am dead, dead to you as can be!"
- The music video makes it even more jarring, showing Em's parents fighting and Em being abused by his mother. This is also mixed with footage of Em in a rainstorm burying...something, and by the end of the video he breaks down in tears and hangs his head.
- His newest song, Guts Over Fear, lampshades the fact that he is coming close to retiring, but doesn't want to since he feels rapping is the only thing he's good at. In the song he feels torn two ways, which can get to you and feel relatable.
- Rock Bottom is just an all-around depressing listen, considering Em wrote it at the lowest, poorest point of his life, and essentially made it to show how crummy his life was from his poverty(made worse by the fact that he had to raise Hailie alongside all this). Hell, even the beat is sad.