The ET review opening is one big Shout-Out to Apocalypse Now, specifically due to the fact that Spoony was doped up after a trip to the dentist.
To Doctor Strange during his review of Final Fantasy VIII when he portrays Dr. Insano selling his Anti-Magic Field Generator kit. Doctor Strange is listed as one of the pesky heroes it is designed to protect against. Also the big flashing ANNATAZ SKCUS subtitle.
Doctor Insano: Dr. Strange? What is he a doctor of, anyway? Subtitle: DR STRANGE IS A PROCTOLOGIST!
At the end of his Strike Commando review, he says he's going to find an American Reb Brown movie, made in America and filmed by Americans... in America. And when the Captain America movies he finds also draw his ire he is interrupted by The Gatekeither.
"Gentlemen, I am Doctor Insano. Welcome to my Creepy Basement."
Two in quick succession to fellow TGWTG members in his review of "Highlander: The Source" - first he refers to a young British character as 'Film Brain' and then adds that facing the Guardian, "He's going to die. A lot." (the catchphrase of Lordkat of Until We Win).
The part in Clones Of Bruce Lee where he, Spencer D. Bum and Dr. Insano react to the woman being karate-chopped in the throat was an homage to Stardust.
In the Swat4 level set in a convenience store, the post-mission wrap-up mentions one victim, Dante Hicks, having been shot before the police arrive. This is actually a reference to the original, deleted ending, in which Dante does indeed get killed by a robber.
He quotes Clerks: The Animated Series throughout the mission: "See, I told you I'd be a good policeman!" "Man, it's cold in here. Like, Hoth cold." "Let's just make sure that we never get locked in the freezer again."
The Ultima IX "BETRAYAL!" Counter is modeled on Phoenix Wright's "OBJECTION!"
At the end of the Ultima IX review, Spoony breaks out a brand new handgun, noting "It's an Anti-Magic Gun, you'll never guess where I purchased it!" in reference to the line "He's got a Magic Gun, where'd he purchase that?" in Atop the Fourth Wall's theme song.
At the same time, the three choices the Guardian presents Spoony with are similar to the choices presented by the Catalyst (Albeit with "Embrace" instead of "Control") at the end of Mass Effect 3, even being presented in a similar way with visions being presented of Spoony shooting the Black Gate (Itself being visually similar to the vision of Anderson presented in the Destroy ending, and what occurs should Shepard actually choose that option), embracing madness & ending humanity's suffering through death, or becoming one with the Guardian. The visions are tinted in the same colors as the choices in Mass Effect 3, albeit with the Destroy option being presented as the Paragon option & Embrace being presented as Renegade. At the same time, "An End, Once And For All" plays as Spoony makes his choice & the entire sequence has music from the game playing throughout.