Slimer is reading a comic book called Rat Toon and wants to share a funny part with Ray, but he's too busy practicing the tuba. Slimer tries to show Peter, but he's too busy exercising, so Slimer tries to show Janine, but she's too busy doing paperwork. He tries to show Winston, but he's too busy working on Ecto-1, so Slimer tries to show Egon despite the "keep out" sign on the door to his lab. However, he accidentally startles him into blowing up the volatile ectoplasm samples he was working with. Peter tells Slimer that he'll be "sorry" if he interrupts them again, causing him to fly into the attic crying.
The Ghostbusters get a call and ask Slimer if he wants to accompany them, but he's too sulky. The guys find a squid-like apparition haunting a retirement home. They try to catch it, but it escapes and sprays them with ectoplasm. Meanwhile, Slimer is eating an ice cream sundae, when he hears footsteps and sees someone behind him. He tries calling the Ecto-1's car phone to warn the Ghostbusters of the intruder, but hangs up before he can say anything, remembering Peter's warning.
The intruder turns out to be Dweeb, with Elizabeth hiding in his outfit, and he tries to catch Slimer with a "twisto ray", which twists up whatever it hits. Slimer uses a mirror to deflect the ray's beam back to Dweeb, and he's spun back into his car. Meanwhile, the Ghostbusters are going home, but Egon is worried because the squid apparition is not in Tobin's Spirit Guide. Then, they get called to a bowling alley where the squid entity almost crushes the guys with falling signs and then steals their proton packs.
Dweeb and Elizabeth sneak back into the firehouse with a ladder, then he catches Slimer with a clamp. Dweeb is about to put Slimer in a case to carry away, but he drinks a lot of water, making him bigger and thus breaking the clamp. Then he spits the water onto both Dweeb and the invention, making it short out and suck up Elizabeth and making his rocket shoes wonk out, sending him spiralling out of control. Meanwhile, the Ghostbusters run away, shooting at the squid apparition all the while, and while they do manage to blow it up, it reassembles itself immediately afterwards.
While Ecto-1 slows down inexplicably, Slimer sets up strings with pots and pans. Then, Egon determines that the squid entity is not a ghost, but rather an entity created from the anger of the ghosts in the containment unit, and that it wants to destroy the firehouse. Peter tries to call the firehouse and warn Slimer, but he's too busy listening to jokes. When the squid entity sets off the pots and pans, Slimer thinks it's Dweeb again, then the Ecto-1 starts flying.
Slimer starts attacking and mocking the squid entity, thinking it's Dweeb, but then realizes it isn't and flies away. Meanwhile, the slime on the Ghostbusters' uniforms comes to life and laughs, and Egon realises that's what's making the car fly, so he tells them to get rid of everything that has slime on it (which includes their uniforms). While Winston and Peter board the Ecto-2, while Dweeb again tries to catch Slimer, this time with some guns called "magnetic flux devices". He accidentally hits the squid entity instead, causing it to slime him and fly off.
When Winston, Peter, and Slimer meet up, Slimer warns them of the squid creature, but they of course already know. Peter has Slimer lure the entity to the staircase, and then the three of them trap the squid monster. Ray and Egon come back and are shocked at the mess.
This episode provides examples of
- 555: The radio station Slimer's jokes come from is 555-YUCK.
- Animate Inanimate Object: The squid monster can bring its own ectoplasm to life.
- Answer Cut: When Egon asks who interrupted him, we cut to Slimer coming out of the tuba.
- Blowing a Raspberry: Slimer blows a raspberry at the squid monster.
- Chekhov's Gun: At the beginning, Egon is testing volatile ectoplasm. Later, he realises this is the same ectoplasm the squid monster was producing, which helps him find out what the monster is.
- Comedic Underwear Exposure: Played for Horror — the Ghostbusters have to strip down to their underwear because of the living slime from the squid monster, but it's still played comedically with Peter being reluctant to do it and the guys wearing Goofy Print Underwear.
- Covered in Gunge: The Ghostbusters, and later Dweeb and Elizabeth, get coated in purple ectoplasm. In the Ghostbusters' cases, the ectoplasm even comes alive.
- Creating Life Is Unforeseen: The ghosts inadvertently created a literal monster just from their anger.
- A Day in the Limelight: Most of the episode focuses on Slimer.
- Did You Just Flip Off Cthulhu?: Peter and Ray directly insult the squid monster several times.
- Dinner Deformation: Downplayed when Slimer eats the sundae — the shape of it can briefly be seen in his belly, but only for a split second.
- Evil Laugh: The squid monster has a low, menacing laugh.
- Extra Eyes: One ghost shown on file has three eyes.
- Flashback: Downplayed when Slimer briefly flashes back to Peter's threat about not interrupting.
- Glowing Eyes of Doom: The squid monster's eyes glow yellow.
- Goofy Print Underwear: Ray is seen wearing boxers with Ghostbusters logos, while Peter wears purple boxers with orange hearts.
- Green and Mean: One of the ghosts whose anger helped make the squid entity is shown as dark green.
- Healing Factor: The squid creature can put itself back together after blowing up.
- Hoist by His Own Petard: Slimer rigs Dweeb's inventions (the twist-o-ray with a mirror and the rocket-powered shoes with water) so they'll malfunction against him.
- Hope Spot: The guys destroy the squid entity... but it can heal itself.
- The Hyena: The squid monster (and its slime) laughs a lot.
- Inevitably Broken Rule: Slimer enters Egon's lab despite the "keep out" sign.
- Inflating Body Gag: Exploited — Slimer drinks water to make himself bigger so he can break out of the clamp.
- Laughably Evil: Downplayed for the squid monster — it's kind of comedic with its living slime, but it's still a threat to the Ghostbusters' lives.
- Lightmare Fuel: The squid monster is a terrifying, killer entity made from pure anger, but its sentient slime is still largely played for laughs.
- Likewise, Dweeb himself, who, in his last appearance, turns in his usual brand of bumbling cartoon villainy. The doctor winds up inadvertently making the monster mad, and it goops him.
- Mind over Matter: Subverted — the squid monster makes the Ecto-1 float, but it turns out he's using the slime to do so.
- Mistaken for an Imposter: Due to Dweeb occasionally disguising himself, and him recently having harangued Slimer, he thinks the squid entity is Dweeb.
- Mocking Sing-Song: Slimer taunts the squid entity, who he thinks is Dweeb, by babbling in singsong to it.
- Mythology Gag: Peter calls Slimer a "little spud", which Ray called him in the original movie.
- Narrative Shapeshifting: Slimer morphs into the squid monster when talking about it.
- Nasal Trauma: Thinking it's Dweeb, Slimer pulls on the squid apparition's nose.
- Not So Stoic: Egon startles when Slimer goes into his lab.
- Oh, Crap!: Slimer turns white with fear when he realises the squid entity isn't Dweeb.
- On Three: Peter tells the others to shoot at the squid entity on the count of three.
- Quaking with Fear: Slimer shakes when he hears Dweeb's footprints.
- Red Is Violent: The squid monster is red, and not only is it very dangerous, it's an entity made from anger.
- Revenge: Egon determines that not only does the squid entity want to kill him and the other Ghostbusters, it wants to first get its revenge on them for trapping the ghosts who created it by destroying the firehouse.
- Running Gag: People keep getting sprayed with ectoplasm by the squid monster.
- Sadist: The squid monster, being an entity created from anger, enjoys seeing the Ghostbusters (the objects of said anger) suffer.
- Scooby Stack: At one point, Slimer, Peter, and Winston appear stacked behind the staircase.
- Slapstick: The explosion sends Peter's exercycle crashing onto Janine's desk.
- Staircase Tumble: At one point, Dweeb's sent falling downstairs.
- Sticky Situation: The squid monster sticks the Ghostbusters to the wall with ectoplasm at the end of its first scene.
- Tentacled Terror: The main villain of this episode is a large, squid-like, noncorporeal being created from ghosts' anger.
- That Makes Me Angry: Peter comments that he's angry after Slimer causes the explosion.
- Totally Not a Werewolf: Due to being noncorporeal and secreting ectoplasm, the squid entity is initially mistaken for a ghost. It's actually a being created from the combined anger of ghosts.
