Due to not taking it at any point during the first three years of high school, Ron's forced to take health class as senior—and he complains to Kim about being the only senior in a class full of freshmen. Ron's health class is also taught by Mr. Barkin (who else?), and the first thing that's taught to Ron and the freshmen is the importance of healthy eating—Ron defiantly tries to prove him wrong by making his diet 'all-Bueno Nacho.' Unfortunately, it takes a nasty turn after he's exposed to a HenchCo chemical.
At the same time, Kim (concerned for her boyfriend's health and well-being) tries encouraging Ron to make healthier choices when it comes to his eating habits while also trying to keep a superweapon out of the clutches of a number of her and Ron's enemies.
This episode provides examples of:
- And Knowing Is Half the Battle: Spoofed in The Tag.
- Big Eater: Out of spite, Ron’s already voracious appetite goes into overdrive as he not only commits to eating Bueno Nacho only, but excessive amounts of it. He even makes up his own orders out of combining differently numbered items on the menu. It’s telling that he ate enough to put on a decent amount of weight before getting mutated.
- Bizarre Taste in Food: As Ron's mutation advances his taste in food changes as well. He starts eating ravenously eating the cafeteria Mystery Meat and then moves on to mini corn dogs while they're still frozen.
- Comically Missing the Point: Ron delivers An Aesop about... not falling into mutagenic chemicals.
- Continuity Nod: When Ron notices that Bueno Nacho now has a breakfast menu, he says that he could practically live here. Kim points out that he ''does'' practically live here.
- Delayed Reaction: During Barkin's assessment of Ron's unhealthy state due to the all-Bueno Nacho diet, he asks for the young man's reaction time. Ron doesn't respond and Barkin moves on to questioning his stamina, something already answered by Ron being asleep in class, Ron then answers that there's nothing wrong with his reaction time.
- Even Evil Has Standards:
- When the villains see Ron's new appearance, they seem genuinely concerned for his health and advise him to start taking better care of himself. Even Monkey Fist (Ron's Arch-Enemy) tells him this.
- When Jack Hench sees a photo of what the mutagenic serum would do to someone, he's not only horrified but exclaims that even he wouldn't unleash that on his worst enemy.
- Everyone Has Standards:
- Ned may be an employee of Bueno Nacho, but he is taken aback when Ron makes a massive order as the first meal of his new diet, asking if he’s sure since it will load him up with a lot more beans and cheese than usual. He eventually gets weary of Ron constantly over-ordering and even making up his own orders by combining different meals.
- Barkin always enjoys getting one over Ron, but as he grows he becomes much more genuinely concerned for Ron’s well-being beyond his usual militant attitude.
- The Fat Episode: Forced by Disney executives, no less. Ron begins overindulging himself on absolutely nothing but Bueno Nacho for weeks on end to try to prove a healthy diet isn’t actually helpful. He quickly gets fat, though the latter half of the episode sees him undergo science-induced growth more than just overeating.
- Fat and Proud: While initially in denial about getting chubby, after being submerged in Project Titan and growing taller alongside wider Ron seems to be pleased with his girth since he's "never felt better." Right before he mutates, he’s happily massaging his belly like he’s downright pleased with his new body.
- Fat Bastard: Ron starts to turn into this the fatter he gets, as the mutagenic serum gradually turns him into a monster.
- Honor Before Reason: Ron literally refuses to admit there are benefits to a healthy diet until after he gets turned into a rampaging monster.
- HULK MASH!-Up: Ron's mutated form is pretty much a fat, orange version of The Incredible Hulk.
- Jabba Table Manners: After getting doused in the Project Titan mutation formula, Ron's eating habits decline, with him stuffing large amounts into his mouth, not even bothering to chew, and spilling bits of food everywhere. A kid at Bueno Nacho comments that he "eats funny". In addition...
- Jerkass Ball: Ron becomes progressively nastier the bigger he gets before finally turning into a monster.
- Just One Man: Jack Hench is bewildered that all the villains and henchmen present at his auction are unable to take down a single cheerleader.Jack Hench: Come on, guys! You can't take down one cheerleader?!
- Karma Houdini: Played with. On the one hand, Jack Hench still avoids any legal repercussions for his actions alongside the fact Ron turned into a monster thanks to his serum. On the other hand, Kim successfully stops him from auctioning off his latest weapon by stealing it from him.
- Laugh Track: Drakken wonders where the canned applause is coming from during the Henchco demonstration.
- Leaning on the Fourth Wall: And then inverting it, as Ron delivers a faux public service message to their viewers, while everyone else stares and wonders, who in the heck is he talking to?
- Magic Pants: As he reverts back to human form, Ron's shirt suddenly changes from his civilian attire to his black mission shirt.
- Noodle Implements: Mr. Barkin's worst nightmare involves Abraham Lincoln and pool sharks, apparently.
- Nutritional Nightmare: Ron's decision to not only eat exclusively from Bueno Nacho but grande size everything he orders. This not only makes him gain a considerable amount of weight but after he's exposed to Project Titan, which needs large amounts of saturated fat, cholesterol, and preservatives to activate, he mutates into a raging behemoth.
- Painting the Medium: Ron at the end.
- Phlebotinum-Induced Stupidity: After Project Titan finally transforms Ron into a monster, he not only becomes more destructive but also much dumber.
- Single Woman Seeks Good Man: Though she does needle him about his weight gain and irresponsible diet choice, Kim is otherwise unperturbed by the change in her boyfriend until he becomes much nastier and capricious, and that’s when she storms out on him.
- Space Whale Aesop: It's pretty obvious the writers weren't that thrilled about being forced to write a Very Special Episode, as they intentionally make the Healthy Eating message about as extreme and unrealistic as possible. Even The Tag lampshades this were rather than talking about healthy eating in general, Ron instead lectures the audience about avoiding vats of mutagenic chemicals.
- Spoof Aesop:Ron: Eating a well-balanced diet will keep you from turning into a mutated maniac?
Kim: Something like that.- Don't enter vats of genetically-altering chemicals.
- Title Drop: After committing to the Bueno Nacho-only diet, Ron tells Ned to "Grande Size me."
- Unskilled, but Strong: After seeing the mutated Ron toss aside his monkey ninjas, Monkey Fist claims that brute force won't stand up against his martial arts skills. Ron is able to completely brush off all of Monkey Fist's attempts to attack him and simply uses his palm to toss him aside.
- Weight Taller: Played With. As far as anyone else can tell, Ron is inexplicably growing taller as he gains weight, which he amounts to the "health benefits" of his new diet. The actual reason is that he's mutating.
- Weight Woe: Two-fold.
- Before being exposed to the serum, Ron's weight gain was portrayed realistically in that he didn't balloon out of shape, but was noticeably chubbier, had less energy, and trouble fitting into his clothes.
- After getting exposed to the serum, Ron's health problems seemed to have vanished as he became not only fatter but taller as well. On the flip side, his attitude took a turn for the worse and he started getting very irritable.
- A Weighty Aesop: Executive Meddling enforced this, which is why this episode exists (complete with subtle Lampshade Hanging).
- Whole-Plot Reference: The whole episode is parody of Super Size Me, down to the title and documentation of eating solely fast food.
- You Are Fat: Kim makes a few snarky, but playful jokes about Ron’s fattening up, which Ron isn’t pleased by. Later, though, after being exposed to the serum, Ron is so gluttonous that he doesn’t process Bonnie’s taunts about his weight at all, too busy eating.
