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- In one of the earliest Cattivik stories, the eponymous thief ends up in the mansion of a senile british hunter, decorated with the preserved heads of fellow thieves. The old hunter promptly tries to add him to the collection.
- Archie Comics' Sonic the Hedgehog: Back when Knuckles the Echidna had his own solo series, one of his foes was a human named Hunter. The first time they meet, Hunter showed off his collection of stuffed Mobians that he had hunted down. Since this series focuses on anthropomorphic animals, Knuckles reacts the way most people would when seeing a wall full of stuffed human heads.
- The Shadow Society in Seekers of the Weird utilizes an army of taxidermied Mix-and-Match Critters.
- The Far Side has two bears looking at a stuffed bear saying "That's Vinnie all right, but his eyes... There's something not quite right about his eyes..."
Films — Animated
- Gru's home in Despicable Me is full of furniture made from stuffed animals. As the girls walk down the hall, they see a stuffed lion's head. In it's mouth is a stuffed dog, with a stuffed cat in its mouth, which has a stuffed mouse in its mouth.
- Madagascar 3: Europe's Most Wanted: Captain DuBois, the head of France's Animal Control, has her walls decked out with all kinds of animals. All she's missing is a lion's head, which is why she specifically targets Alex.
Films — Live-Action
- Captain James Hook in the movie Hook, meets his end when the Crocodile he "had stuffed and turned into a village clock" (paraphrased) comes back to life at the end of the movie, and swallows him alive.
- In the film version of The Neverending Story, Bastian is scared by the taxidermied head of a wolf.
- The house in Evil Dead 2 is full of creepy stuffed trophy heads. Who laugh at Ash.
- In Night of the Living Dead (1968), Barbra wanders into the house's trophy room, where the stuffed heads seriously freak her out. Although not as much as the corpse. Or the zombie. Or Ben.
- In The Lost Boys, Sam wakes up to discover that his grandfather has left a stuffed woodchuck in his room to "brighten up the place". It freaks him out to the point that he tossed a shirt over it. The shirt is still covering the woodchuck at the end of the movie, indicating that Sam found it more disturbing than the vampires he just had to fight.
- In Road House, Tinker, the only survivor among the Big Bad's Mooks, is so freaked out by the various stuffed animals surrounding him that he can't testify to the Sheriff about what happened in the climax.
Tinker: "A polar bear fell on me..."
- Alfred Hitchcock filled Norman Bates' house with taxidermed birds to add to the creepiness in the film version of Psycho. It also alludes to the final fate of Mrs. Bates.
- In the Friday the 13th (2009) remake, Lawrence tries to masturbate in the living room, but finds himself too creeped out by a big stuffed moose head staring right at him to go through with it.
- The 1994 live-action adaptation of The Jungle Book has Mowgli in a room filled with stuffed animals, and he imagines hearing them screaming, with each scream punctuated by a gunshot.
- Done to terrifying effect in Livid in which stuffed animal heads are put on dolls at a tea party.
- Ace Ventura has a truly epic Freak Out! in Ace Ventura: When Nature Calls when his new employer becomes a little sick of his antics and shows him his trophy room, as "one animal lover to another". When asked if there was something wrong, his response is "Of course not, this is a charming room of death!" Gets a Call-Back later when the Big Bad and his cronies are in said room, and are looking around at the various stuffed animals/heads as numerous roars are heard, right around the time a stampede of various jungle animals comes crashing through the wall. With Ace riding in on an ostrich in the middle of it.
- In Roxanne, one minor character tries to impress the titular female lead with his taxidermy and hunting store, named "All Things Dead". She's not impressed.
- Beautifully played with in The Cabin in the Woods. The titular cabin that the college kids go to has a stuffed wolf's head mounted on one of the walls, which creeps them out. In the evening, when they're playing "truth or dare", Jules is dared to make out with it. She does so, and then nothing happens. Despite the cabin being an Eldritch Location situated above a whole lot of Sealed Evil in a Can where college kids are ritualistically slaughtered every year, this wolf's head turned out to be a harmless decoration.
- in The Frozen Ground the serial killer Robert Hansen is first shown in his home, adorned with various pelts and mounts, which you can see in nearly every shot. Later in the movie it is reveled that there are so many mounts because he has an addiction to hunting, and human beings are a harder kill.
- The Neverending Story. Bastian sees the taxidermied heads of a fox, an eagle and an owl, and later in the land of Fantastica he meets three sages with the heads of said animals.
- In The Hotel New Hampshire, the family dog dies and the protagonist's older brother decides to take it on as a taxidermy project. It comes out looking far more terrifying than it's supposed to, and keeps getting found in various unexpected and startling places. At one point it keeps the protagonist from getting laid by frightening the girl; at another, it literally scares his grandfather to death.
- In the Fablehaven series, Seth has to sneak into a mortuary that had stuffed animals standing around. Turns out the guy who owned the place wasn't actually evil, but it still scared the crap out of Seth.
- A stuffed SS Standartenfuhrer is a prized possession of Cristobal Junta, the Magitek scientist from Monday Begins on Saturday. Played for Laughs.
- "The Mutation" in Animorphs had the group going into an undersea cave and stumbling into a whole museum of stuffed humans on ships(with a few just-added Hork-Bajir in the mix as well.)
- In Wings of Fire, queen Scarlet has a bunch of stuffed humans and taxidermied reptiles.
- In Varjak Paw, stray cats are being killed and stuffed. People buy them thinking they're just dolls when they're actually taxidermy. To cats, they're creepy and uncanny.
- Ned from Pushing Daisies is afraid of taxidermy animals, as related in the episode "Frescorts", but that's more because he can bring them back to life with a misplaced touch than anything to do with taxidermy being inherently terrifying. He mentions an incident of a polar bear rug coming to life and totally killing the mood.
- On Heroes, Danko comes home to see a taxidermied rabbit sitting on his table. He's understandably confused and creeped out, not knowing that Sylar is hiding in the shadows the next room over.
- Doctor Who example: Ace gets trapped in a room full of this, and freaks out, during "Ghost Light."
- The Janitor on Scrubs has an extensive collection of stuffed animals, and likes to make additions whenever some small and furry creature crosses his path. They all have names as well, and he likes to play with them.
- In the video for the Genesis song "No Son of Mine," there's only one animal head, but it's still pretty freaky.
- TimeSplitters: Future Perfect has a taxidermied moose head in one room of a creepy old mansion that comes out of the wall with a zombie body as a mini-boss.
- The first game also has a moose head, also in a haunted mansion, although here it is simply a disguised turret that shoots you when you're in the same room.
- In World of Warcraft, there is a boss fight with one of these. It begins with two random trophy monsters unfreezing, attacking you. Then Gortok Palehoof unfreezes from the other side of the room and charges your group, starting the actual boss fight.
- In Rama, the stuffed alien may not raise your eyebrow. The stuffed co-worker, however...
- The Safari Room in Luigi's Mansion is filled with various stuffed creatures, which nod kind of creepily when the Poltergust 3000 is used on them.
- In the Ambridge Mansion series, in your nightmare you see what seems to be the skin of a shadow monster stuck on the ceiling and dripping blood.
- In the flash game Haunt The House two of the objects the player can possess to scare people is a stuffed bear and a moose head.
- In Kingdom of Loathing, a revamp to Spookyraven Manor in May 2014 added spooky taxidermy animal heads to the Haunted Billiards Room (part of a side-quest involves investigating them more thoroughly) and the stuffed moose head monster.
- Dungeons & Dragons
Several small animals and birds are sitting on shelves and tables. They are regarding you with unwinking stares!
- Module EX2 The Land Beyond the Magic Mirror. When the PCs first arrive in Murlynd's house they're in a room with stuffed animals. The description makes them sound scary.
When the door is opened there comes a low, rumbling growling noise, and a grizzly bear, on his hind legs, comes lurching out of the shadows. He rushes right at the head of the party.
- Module A2 Secret of the Slavers' Stockade. When the PCs open a door they get a shock from a stuffed bear.
- Pathfinder, being very fond of exceedingly non-standard monsters, has the "Taxidermic Creature" template in its 5th bestiary, which is a sort of necromantic animated object applied to stuffed or otherwise preserved animals so they can come to life and attack the party.
- Arguably predated by the even creepier Pickled Punks of 4th bestiary, which are deformed fetuses/babies preserved in alcohol that have been animated as blood-sucking undead monsters.
- The Carrion Crown adventure path has, in the module "Shadows of Gallowspire", has the Asphyxiating Taxidermy haunt; a room or corridor full of taxidermied heads that spontaneously start gasping for air, which can mystically suffocate the players.
- The Ducktators: Kind of. The heads of Hitler, Mussolini and Tojo are stuffed and hung on the wall, but here it is played as a victory upon evil. The actual terror has been turned into taxidermy.
- Gravity Falls features a load of this in "Northwest Mansion Mystery". When the Lumberjack Ghost first manifests itself to Dipper and Pacifica, it makes a room full of mounted animal heads speak in unison and ooze blood-red ichor. Later, the Lumberjack Ghost animates some more stuffed animals to attack the guests at the Northwests' party.
- Mr. Burns of The Simpsons has a huge stuffed polar bear in his office.
Mr. Burns: Oh, Lenny, why would you steal my bear?Lenny: I just wanted something to cuddle at night.Mr. Burns: That's my cuddle bear! I loved him! I shot him! He's mine!