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Anime and Manga
- One of the countries that Kino encounters is the last remaining member of a "democracy" that voted by majority. Ultimately, everyone else had voted each other to death until one man and his dying wife were left.
- I Am Legend follows this premise.
- The Quiet Earth: With apparently no-one else left on Earth, protagonist Zac Hobson sets a radio station to emit a message in case anyone's out there, moves to a mansion, raids shopping centres, plays with train sets in a store- and then the real trains- cracks up, starts dressing up in women's clothes and declares himself emperor of the world before an audience of cardboard cutouts. (He gets better.)
- The French movie Seuls Twonote is about two people waking up in a completely deserted Paris.
- In The Omega Man, Charlton Heston doesn't take much advantage of this trope, since he spends his time hunting zombies. However, his love interest, Lisa, likes to go "shopping" in abandoned department stores. At least until she gets The Virus and does her Face–Heel Turn.
- In Night of the Comet, the two protagonist teenage girls spend much of their time looting abandoned department stores for cool clothes.
- The main cast from 28 Days Later have a Hope Spot moment raiding food from an abandoned store, and in the first scenes, Jim absconds with a bag full of soda cans from a derelict vending machine. On a darker note, since the original owners are dead, the soldiers have set up camp in an abandoned country estate, and govern from there, at one point forcing the girls to dress up in the clothing of the former lady of the house for the pleasure of the men about to rape them.
- In one of the short films made with the sequel, a man left in this situation kills himself out of loneliness. As he's dying he hears the helicopters returning.
- The protagonists of both the original Dawn of the Dead (1978) and the remake do this on a smaller scale with a shopping mall. In fact, this is largely the point (of the older movie, at least).
- The heroes of Zombieland don't limit themselves to one town, but they raid grocery stores for food (in search of the elusive Twinkie), trash a store just for fun and crash for a while in Bill Murray's mansion (which isn't as abandoned as they thought).
- In Freddy's Dead: The Final Nightmare, there are no children or teens left in Springwood, yet the adults still put on a pitiful show of a town fair, complete with kiddie entertainments no kids are around to enjoy. The school and orphanage are likewise left to fall apart, each with a crackpot staff member left behind to pretend they still have kids to teach or care for.
- The Stand had one bomb-happy character blow up oil storage silos for the explosions, since no-one was going to stop him.
- Hell, half of the secondary characters, especially those left in NYC, go wild with their fantasies. One guy runs into two survivors in the park and tells them he's gleeful the world is gone. Why? There's no one left to stop him from jerking off on home plate at Yankee Stadium. This is one of the few relatively benign examples.
- Ofelia from Remnant Population stays behind after the rest of her colony is moved to another planet, and she is left as the only human on the entire world. She's not completely alone, though...
- The protagonist of the post-pandemic London of John Christopher's novel Empty World.
- This trope is a plot point in the zombie-apocalypse novel World War Z. When The Cavalry finally arrives in some reclaimed towns, they are never quite sure if the Mayor has all his or or her marbles.
- Jadis, the Last Queen of Charn from The Chronicles of Narnia. In The Magician's Nephew, we find out that she single-handedly eradicated every other lifeform in her universe because her sister had raised a rebellion against her queenhood; with her sister's army at the door, she proved herself to be a sore loser. She then magically preserved herself as a statue until the heroes accidentally freed her, then hitched a ride with them to Earth and ultimately to Narnia, where she became known as the White Witch.
- Played literally in the children's book Ghost Town Adventure. A family on a road trip comes across Ruby, a Ghost Town with exactly one resident - Mayor Abe Winters. It had been a thriving town during a gold rush but when the gold dried up everyone else in town abandoned the place. Abe figures that even though his term expired he's still the mayor until he gets voted out.
Live Action TV
- Red Dwarf follows this premise. A radiation leak kills the entire crew of a ship the size of a city, leaving only the initial cast.
- On MST3K, the robots are asked what they would do in this situation. Servo would put bricks on accelerators and drive cars off cliffs all day. Crow would put on football pads and dive through pane glass windows up and down main street.
- My Name Is Earl had a flashback episode where the main characters think that Y2K has killed everyone else in town so they move into a supermarket and each of them claims part of the store as their own personal domain.
- Burgess Meredith's character in the Twilight Zone episode "Time Enough At Last" finds himself in this position after surviving a nuclear attack by virtue of being in a bank vault at the time, much to his pleasure (at first).
- The titular The Last Man on Earth spends the first episode having fun using the town of Tucson as his own personal playground. The second episode has other survivor Carol elect him President. After the other Phil shows, they have another election against Old Phil's will. New Phil wins.
- The Sarah Jane Adventures has an episode where Rani and Clyde find themselves alone in, as far as they can tell, the whole world.
- BIONICLE plays with this in the description of what the Toa Of Light was flying around doing in other dimensions. The villanious/Heel–Face Turn applying Toa Tuyet in an alternate dimension specifically ignored and never mentioned outside of descriptions of said alternate dimension) specifically says (while contemplating drowning everyone in the alternate universe) that she would be ruling over an empire of corpses.
- The mayor of Shanbar in Return To Zork. The eastern half of his town has completely disappeared, the western half is empty except for himself and three other survivors, and you're the first visitor he's seen in ages.
- Dragon Quest VII has this happen to Suifu in the Penal Colony where all the refugees/prisoners from Dharma Shrine are being held. Once the problems are solved, he finds himself alone, ruefully admitting that he'll never enjoy the sort of power and position he was able to claim for himself there.
- Suikoden V's Tageyl stands on the verge of this: Lordlake has fallen out of favor with the queen and is slowly dying without any water.
- Impaz from The Legend of Zelda: Twilight Princess, the last inhabitant of the Hidden Village, who turned down a chance to escape from her Bulblin-occupied village so she could give the Ancient Sky Book to the messenger of the heavens (a.k.a. Link).
- King Daphnes Nohansen Hyrule from The Legend of Zelda: The Wind Waker is the only person left in Hyrule after it got sealed beneath the Great Sea, using his position to guide Link and awaken Zelda. He decides to use the Triforce to drown Hyrule and himself in order to save Link and Zelda and defeat Ganon.
- Shade is not the last survivor of desertified resort town Oasis in Borderlands 2. There's plenty of colorful characters who are totally alive and not mummified corpses. They have such great conversations while not slowly dying of thirst. Please stay!
- One of the most dramatic examples is Andrew Ryan in BioShock; even as Rapture slowly began to break apart, its people going mad and slaughtering each other in its halls, he remained convinced that it would all be well and good with just a little more time...
- Distinct possibility in Dwarf Fortress. Most fortresses will eventually suffer catastrophes and get wiped out, but in case one of the inhabitants became a vampire, he/she is much likely to survive and keep the fortress going as the sole inhabitant as he/she requires no sustenance.
- Played for laughs in Homestuck. The Wayward Vagabond, a non-human wanderer of post-apocalyptic Earth, is fascinated enough by the idea of democracy that he becomes a mayor over a stash of cans.
- It's less humorous now that fans are speculating he did this as a coping mechanism after two entire armies he was leading were slaughtered in front of him in a matter of seconds, leaving him as the only survivor.
- Named for the The Simpsons episode in which Homer divides Springfield into two towns, Old Springfield and New Springfield. When Homer erects a wall to this effect, the citizens of New Springfield quickly realize that they suddenly have no means of obtaining supplies. All but the Simpson family climb over the border, leaving a disgruntled Homer alone, to which Bart says 'Face it Homer, you're mayor of a ghost town!'
- Homer also has the run of Springfield for about half a Treehouse of Horror segment, after a Neutron Bomb kills all the people. And turns many others into cannibal zombies.
- Moe became Emporer of the starved lawless en-domed Springfield by chucking grenades at anyone who challenges his authority in The Simpsons Movie.
- Pinky and the Brain, when Brain manages to take over the world by luring all its inhabitants to the doppelganger planet Chia Earth (which is made of papier-mache). In the end, he goes so mad with the boredom of ruling an empty planet that he decides to put forward a bunch of bills, then use his presidential powers to veto them. For fun.
- This is how an alternate-future version of Vandal Savage has lived for thirty millennia in the Justice League episode, "Hereafter."
- In the Grand Finale of Avatar: The Last Airbender, Ozai apoints Azula as the new Fire Lord while he goes off to end the war (and gives himself a new title denoting supreme ruler of the world). Azula's increasing instability and paranoia means she ends up gradually banishing every member of the Royal Household (and, possibly, everyone in the Fire Nation capital) other then the few people needed to coronate her.
- An episode of Duckman had the whole town perform an "emergency drill", only to get trapped in the shelter underground. Only Duckman (who slept through the alarm) and a deaf woman (who couldn't hear it) remain, convinced they are the last people alive. So Duckman engages in his every hedonistic desire; tooling around in a motorcycle, stealing things, blowing up buildings, and unknowingly causing hell for the people trapped below.
- WALL•E provides a robotic example, with the ghost town being the abandoned, overpolluted Earth.
- Played literally for six French communes which still legally exist and thus have a mayor named by the prefect in spite of being totally destroyed during World War I.
- Rotten boroughs: Until 1832, some British MPs had constituencies with very few voters, due to the towns having declined centuries earlier. E.g. Old Sarum, Wiltshire, had only seven voters and no standing houses.
- The western USA has a few mostly abandoned settlements which would no longer appear on the map if not for one or two remaining residents.
- Monowi, Nebraska is the only incorporated municipality in the United States with such a population.
- The smallest community in Germany to have its own mayor is Hallig Gröde, an island in the North Sea, population 9. It used to have a bit more people on it in the past. In 1825 there were 90 people. Papers love to interview the "mayor" for tourism pieces.