The joy that covers Wayne Brady's face at the sight of Laura Hall is extremely touching. You can tell that she is a joy to Drew, as well.
One session of Party Quirks in the UK version had part-time performer Jim Meskimen as a "reminiscing old man" - even after he'd been guessed out, he took a little time to address Clive without breaking character. Maybe it was a jab at Clive's advanced hairline, but for all intents and purposes it worked.
In the US version, the infamous "heavily pregnant Colin at the amusement park" session of Sound Effects ended with Drew tossing US$100 bills at Colin and Ryan - who agreed that the two ladies providing the sounds were the ones who'd earned that money, and got up to hand the dollar bills to them.
During another segment of Drew giving out $100 bills, Ryan catches one, then gets up and places the bill on the band's keyboard.
The Foreign Film Dub session with special guest Sid Caesar led to a few Show Stopper moments, not the least of which was Sid himself giving a symbolic nod to Colin's "garlic press" line, acknowledging the resident Pungeon Master.
The standing ovation when Sid Caesar comes out for his guest appearance - it lasted for so long that it had to be cut down for broadcast.
Ryan's contribution to the Colin Hoedown, and Colin hugging him afterwards.
In a session of Whose Line, depicting "a Vietnamese woman bidding farewell to her GI boyfriend at the end of the war". Ryan decides to milk it a little by adding a Reveal of his own... and then one of the prewritten notes takes it to the next level.
During one episode, a woman in the audience is wearing a shirt that reads "Wayne, please sing to me!" Drew does in fact select her from the audience during Duet for Wayne and Chip to sing to. About halfway through the song, Wayne starts to dance with her. The expression of absolute joy on her face through the entire thing is wonderful.
From the 100th episode's Scenes From A Hat: After 100 episodes of repeatedly making fun of Colin being bald, the scene drawn is "A brief glimpse into the dreams of Colin Mochrie." After a skit of Greg rubbing his hair, with Colin looking visibly upset at the umpteenth bald joke made at his expense, Ryan's contribution is himself, Wayne, and Greg, all bald and screaming. Also counts as a Funny Moment.
While not a straight example, the "Newsflash" session that started with the green screen showing the studio cam's current view instead of the archive footage intended, leading to Ryan and Chip reaching to the side to make gestures around Colin's head. It's so juvenile that it's adorable.
In another playing of Newsflash, the green screen is showing clips of Ryan from previous episodes. Colin eventually figures it out as always, and when Drew asks him what he thinks is behind him, Colin's answer is a straight-laced "I think it's my good friend Ryan Stiles".
Colin and Ryan in general are just plain heartwarming, as the two have been friends and colleagues in improv for years. That's why they're so great together, because they know each other inside and out and can play against each other perfectly.
This game of Infomercial had Colin place a device in Ryan's mouth and prepare to turn a knob on the side. Suddenly Drew begins yelling in protest, recognizing the device as dangerous. Fortunately the one in question was empty.
Of course, this being Whose Line, it quickly turns into a moment of funny as Ryan plays it off with the crack "Someone wants his own show!"
In one episode, Drew nearly choked on an Altoids, and slumped over his desk as he attempted to get it out. The four contestants looked extremely concerned about him—Wayne even calling out "Drew, are you okay?" Drew had suffered a heart attack some time earlier, which makes their concern for him even more heartwarming.
The look on Wayne's face when Lassie trots on-stage as a special guest Duet subject. He's like a little kid, it's adorable.
And Ryan in the back just melts. Ryan's noted to be a big dog lover in Real Life.
Ryan's performance as a lost toddler in a game of Weird Newscasters just wants to make you go "awww..."
During the Body Odor Hoedown Ryan experiences an Epic Fail and can't come up with a line. To give him a hand Drew comes up and stands behind Ryan and sings a second verse while Ryan lip-synchs it.
A meta-moment before the show even started: executives didn't want Ryan and Colin to be on the show, thinking they were "too old" to appeal to a younger audience. Drew put his foot down and refused to do the show if they weren't involved. Of course, this paid off immensely, as the wealth of examples on all these Whose Line pages can prove.
In one "Party Quirks", Ryan's quirk was that he was excited by ugliness. During the scene, he was all flustered by Drew. After the game, Drew said in a mock dejected manner: "A thousand points, that's all I'm good for is giving points." Ryan responded: "Hey, buddy...", and defiantly ripped up the card which contained that suggestion.