In the fourth-season finale, "Wilson's Heart," when House's team realizes Amber (formerly their rival for a spot on House's team, more recently Wilson's girlfriend) is dying and nothing can be done for her:
Thirteen: We should say goodbye.
Taub: She didn't even like us.
Kutner: We liked her.
Taub: Did we?
Foreman: We do now.
- This probably counts as a Tear Jerker for most tropers: the scene where Wilson is trying to process the aforementioned information and Cuddy comes in to tell him that they can wake Amber up so that they can say good-bye to each other. This finally causes Wilson to break down in tears (the first time we see him cry in the show), prompting Cuddy to take him in her arms.
Cuddy: We can wean her off anesthesia, wake her up, give you a chance to...
Wilson: Don't be cruel. Don't.
Cuddy: Wake Amber up. See her again. Tell her what she means to you.
Wilson: Wake her up to tell her that she's...(shoves his palms into his face in agony)
"You want to kiss me, don't you?" "I always want to kiss you."
- House and Wilson at the end of "The Social Contract."
- This exchange at the end of the season 6 premiere made this troper feel all fuzzy inside, when House is being discharged from Mayfield, and they're having his Re-Birthday party:
Alvie: (runs up with the intentions of throwing his arms around House)
House: Back off. People already think we're gay.
Alvie: (steps away, looking disappointed)
House: (smiles and tugs Alvie closer and hugs him tightly)
In "Fidelity," when Cameron tells House about her first husband with metastasized thyroid cancer while crying in the lab.
Cameron: Iím re-calibrating the centrifuge.
House: Turn around. Itís a very sad thing, an un-calibrated centrifuge. It makes me cry too.
Cameron: Iím not crying.
You canít be that good a person and well adjusted.
House: Because you wind up crying over centrifuges.
Cameron: Or hating people.