To add further tickle-value, it's basically a perfect mini-adaptation of Nineteen Eighty Four.
Hyde singing while he approaches the Tripod. Jess Nevins, who catalogues all the references, says that he wants the original piece of artwork for that six-panel sequence.
To make it even funnier, the song he sings ("You Should See Me Dance the Polka") comes from the 1940 adaptation of Dr. Jekyll and Mr. Hyde with Spencer Tracy.
Every time you suddenly get the subtle nods to famous pop culture icons - like suddenly realizing that "The New Traveler's Almanac" has a cryptic nod towards The Big Lebowski, or recognizing that Alan Moore manages to quote Barney Fife in The Black Dossier.
Orlando cock-blocking Adam Adamant in Century 1969 by bragging about his Arthurian days.
At the beginning of The Black Dossier, Mina beats the tar out of "Jimmy" after spending about ten-odd pages posing as a shallow bimbo named "Oodles O'Quim"note In Britain, "quim" is slang for female genitalia, by the way.... Later, when Allan shows up to drive her away, he berates her for choosing such a stupid-sounding alias, but Mina assures him that Jimmy was convinced. Allan just shrugs it off and says, "He must meet women with stupid names like that all the time..."
Harry Potter shooting lightning from his crotch. Mature? By no means. Funny? Yes.
The entire sequence of seeking out the Antichrist is Comedic Sociopathy and the joke is that the Antichrist is pathetic, a blubbering, pill popping jerk who locks himself away in a room for days but then stays there for years.
Skinner takes advantage of his invisibility to sneak up on the League and pinch Mina's butt. Once she realizes who did it and where he's standing, she slaps his unseen face.
"You are to be clothed at ALL TIME!!" - it's funny in context.
Dorian: If that had been permanent, I'd have been very upset!
A bit of small minor humor between Sawyer and Mina. First him trying to make small talk to get over the fact that he watched her first act of Vampirism as well as telling her she missed a spot. Second, Sawyer despite Allan's advice not to, tries and fails to flirt with Mina despite seeing what she did. Bonus points for her teasing him, by only rejecting him for being "Sweet and Young." When he later uses Nemo's Car as part of the plan to save Venice, the impressed look on her face pretty much comically took back what she said to him. Lastly when Venice is saved, Sawyer came back with a bloody lip. She goes to check his wound, but his Genre Savvy senses kick in and he backs away from her breifly, to which she says the following.
Mina: Don't worry, I've had my fill of throats for this evening.