Adam Freeman
- Chronic Hero Syndrome: He has a tendency to go out of his way to help people no matter what, which Cindy notes in Creature in the Teacher and she actually finds it quite admirable.
- Nice Guy: He's probably the second nicest of the main characters, next to Cindy.
Sally/Sara Wilcox
- Adaptational Nice Guy: Mildly, her somewhat rougher moments are toned down in the TV show. Not having Cindy around as much likely plays a part.
- Anti-Hero: Downplayed, but she's the edgiest of the main characters by far
- Deadpan Snarker: Pretty much constantly.
- Hero with Bad Publicity: Time Terror reveals that in the future, she is not considered a hero due to always causing trouble for the group and is even called "The Evil One".
- Good Is Not Nice: or soft, in her case. While she's a good person, and risks her life to save people in numerous books. she can be quite rude a lot of the time, and is downright ruthless in a few cases (such as planning to blow up an alien spaceship even though she's not sure they're evil or not.)
- Jerk with a Heart of Gold: Sally may be pretty, vain, sarcastic, and overconfident, but is a pretty decent girl over all. Also, even though she's always fighting with Cindy, she really does care about her as in one book Cindy is seemingly killed by a pterodactyl Sally is really upset and even starts crying.
- Loving Bully: Possibly why she's so mean to Cindy: she has an outright Heroic BSoD when she thinks Cindy is dead, and another book admits Cindy doesn't really hate her and actually admires her, which implies there may be something between them.
- Must Have Caffeine: She's so tense most of the time that she drinks multiple cups of coffee a day just to feel normal. In Phone Fear she jokes that she wants to get rid of the person who invented coffee to end her reliance on it.
- Pet the Dog: Has quite a few of these, including risking her life to save her friends numerous times (even strangers), and being prepared to pull a Heroic Sacrifice at a few points. She has some smaller things to, such as holding Cindy's brother's hand in the show.
- Proud Beauty: Zigzagged. While she often acts rather vain, there are a few cases that suggest she's actually pretty insecure about her looks. In the very first book she asks Adam at one point if he thinks she's pretty, he says she says she "looks alright", at which point she slugs him and says he "has a lot to learn about insecure females". She also frequently suggests Cindy isn't very attractive, but, judging from the other characters and the pictures of her, she's at least as pretty as Sally is, so it's probably just more insecurity on her part.
- Tsundere: Definitely a type A. Despite usually being rude and abrasive, she can be surprisingly compassionate (even to Cindy), and usually knows when to drop the attitude if someone's really scared and upset.
Watch
- Adaptation Dye-Job: He has light, possibly blond hair in the books, and brown hair in the show.
- Dark and Troubled Past: It's implied he had one, as his family left him years ago and it's stated he did not have an easy childhood. The specifics are never revealed though.
- Only Known by Their Nickname and Only One Name: His real name and last name are not revealed, and it is implied he has forgotten them. Although the TV series reveals his last name is Waverly.
- Platonic Life-Partners: With Sally in the show. In the books they are less close.
- Shrinking Violet: He's a shy and nerdy but kind-hearted kid.
Cindy Makey
- Adaptation Dye-Job; She is a blond in the books, and has black hair in the show.
- Demoted to Extra: She only appears in one episode of the TV show. This is because they didn't have the money to pay for an extra actor in the main cast◊. However, in the planned second season, she would have been added to the main cast.
- Hair of Gold, Heart of Gold: She is blond and probably the nicest in the group.
- The Heart: She's probably the most sensitive and caring of the main five.
- Informed Flaw: Sally often implies she is some kind of spoiled princess type, but this is far from the truth. It's even a plot point in The Witch's Revenge but she's never shown signs of this otherwise.
- Light Feminine and Dark Feminine: Light to Sally's dark.
- Vitriolic Best Buds: With Sally. One book straight up admits she only pretends to hate her and secretly admires her.
Bryce Poole
- Adaptational Jerkass: In the show, he's not some kind of secret agent and just a dull-witted bully. He also is only in one episode.
- Badass Adorable: He's only 12 yet is known as a hero on multiple planets
- Distressed Dude: In the later books, he has a tendency to get in some sort of danger, from getting captured by a creature that imitates him twice, to getting hospitalized in Phone Fear, to getting full on erased from time by accident in Time Terror.
- Mr. Vice Guy: Pride would probably be his, although, to be fair, he has a lot to be prideful about.
Ann Templeton
- Adaptational Villainy; In the books she is generally on the good side despite her shadier moments, while the series has the shady side being played up more.
- Age Lift: The TV series changes from her an adult who seems to be around her late 20's to a teenage like the main characters.
- Anti-Hero; In the earlier books, she is helpful enough but rather shady and has various stories circulating about her, even if most are likely false. She becomes gradually nicer to the group as the continues, especially to Watch.
- Evil Redhead: The evil version of her in The Secret Path has red hair.
Bum/The Mayor
- Crazy Homeless People: Subverted in the books, as he is well put together but played straight in the show.
- Demoted to Extra: His role as Mr. Exposition is diminished in the show, so he doesn't appear as much. However, he does get a whole episode about exploring his mind.
- Harbinger of Impending Doom: He plays this role in his quick appearance in the first TV episode.
- Only Known by Their Nickname: In the books, he prefers to just be called Bum while in the series, he's likely forgotten his real name. Although the episode The Maze reveals it during a flashback.