- Implacable Man: Max himself is far more durable than normal humans, especially prevalent when he goes up against small-time thugs instead of his usual rogues gallery.
- Mana: Max's nanoprobes run on Transphasic energy; it seems capable of powering mechanical devices without actually following a constructed electric circuit, but burns up quickly.
- The Symbiote: Mutualism; once the nanoprobes enter Josh's system, his body adapts to their presence and they become a biomodification. The fact that Josh's body doesn't remember how to work without them, coupled with how quickly they consume their energy source, is often a plot point. Taken further in season 3 where the primary power source is lost and it's implied that Josh will eventually die with only the smaller backup source trying to fill in for it.
Roberto "Berto" Martinez
- Smart People Wear Glasses: Serving as the brains to Max's brawn.
- Heel–Face Turn: Cytro is built to destroy Max, but grows beyond that programming and becomes Max's ally.
- The Worf Effect: At hands of Toxzon and Makino in separate movies; The smog toxoid may be another example, but at least in that case Cytro wins the second match.
- Disney Death: At the end of season 1.
- Evil Brit: Dread's accent is subtle and hard to place, but it seems vaguely British.
- Good Scars, Evil Scars: Played straight with Dread's burned face.
- Villain Ball: Dread misses more than one chance to kill Max because he wants him alive to study his biomodifications, and Max, every single time, escapes and ruins his plans.
- Villainous Breakdown: A minor one in his last appearance, where he expresses shock at Max coming back from the most impossible situation he'd ever been in. It's not very spectacular, but it's a major display compared to Dread's usual calm, professional demeanor.
- Arch-Enemy: While he worked for Dread, he's arguably the more personal enemy for Max.
- Chewing the Scenery: Psycho will be cool, collected and creepily calm one minute, and be the largest ham ever the next.
- Disney Death: Psycho goes through a lot of these, to the point where both he and Max lampshade it. Taken to its absurd extreme when Psycho is thrown into space with no means of stopping his inertia or changing direction, to say nothing of re-entering the atmosphere without burning up and landing without going splat, but comes back a few episodes later.
- The Dragon: To Dread at first. He begins acting on his own during the last season.
- Genre Savvy: He ventured into this sometimes, though never quite enough to save him.
- Obviously Evil: With a face and name like his, you wouldn't think he was a gardener.
- Only in It for the Money: Surprisingly. Once his old employers get taken apart, his plans more-or-less boil down to "Do something evil to make a quick buck."
- Post-Mortem Comeback: All those Psycho Robots he left scattered around the world, specially those with a doomsday device in the "Countdown" movie.
- Psycho for Hire: Hee.
- Slasher Smile: Sports the one of this.
- Thanatos Gambit: When he was finally Killed Off for Real, he left some Psycho Androids to guard a doomsday device as a final vengeance.
- Villainous Breakdown: He is less than thrilled when he hatches a plot in season 3 that has nothing to do with N-Tek or Max like all of John Dread's schemes, but it turns out Max is there anyway by sheer coincidence.
Bio-Constrictor (Dr. David Klimo)
- Body Horror: His body is made of snakes
- In-Series Nickname: The abbreviated Bio-Con.
- Killed Off for Real: By an exploding Psycho Android.
- Reptiles Are Abhorrent: Especially when they're what he's made of.
- The Worm That Walks: He is actually composed of many slithering snakes.
- Power Glows: His arms glow when he shoots energy.
- More Teeth than the Osmond Family: He has two sets of teeth, like those of a shark.
- Motive Decay: His original motivation was to carry on the eco-terrorist plans of Bio-Constrictor. By "The Toxic Legion" he's just interested in Morphososnote
Extroyer (Troy Winter)
- Animorphism: Can morph into animals by "Extroying" them.
- Evil Counterpart: As Troy Winter, he is a former extreme sports star turned super agent, just like Max.
- Power Armor: As Troy
- Spikes of Villainy: After getting the Morphosos embedded on his body, he gets rather spiky.
- Steven Ulysses Perhero: His name Troy Winter, is part of his new identity.
Toxzon (Tytus Octavius Xander)
- Big Bad: Both times that the villains had formed a team, Toxzon has been the leader.
- Evil Former Friend: To Ferrus.
- Punny Name: Toxzon sounds like toxin.
- Steven Ulysses Perhero: The acronym of his name, Tytus Octavius Xander, is part of his mutated form's name.
Makino (Mike Nickelson)
- Going for the Big Scoop: Before his transformation.
- It's All About Me: He refuses to evacuate the danger area, steals Berto's equipment instead of saving him, and what does he do when Elementor's toxic storm fuses him with such equipment? Blames N-Tek.
- Walking Shirtless Scene: The organic side of his torso shows that he's shirtless.