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topsiders immune system have degraded after so much time spend in those suits
If the flash backs/ditto projections can be trusted it took between several minutes and several hours for humans to transform into monsters/anthro's after exposure, but the topsiders seem to transform in seconds after suit breaches.

The virus is sentient and making choices

Transforming people differently if they are awake, asleep or somewhere in between and giving a healing power to anthro's sounds like too much for a virus to achieve on its own.But then again, werewolves and vampires in modern fiction are often created by viruses.

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