Mayor Waters mentions how the vegetal Kingpin is stored inside the mayoralty and brought to him once a year just so Waters can eat in front of him to torture him. At the end of the story, Kingpin was presumably still inside the building when Spider-Man destroyed it. Though considering his state, this may have been for the best.
The revelation that Peter Parker accidentally caused Mary Jane's death thanks to his radioactive semen can make one wonder if this is just a unique case to this reality's Spider-Man or if many other Mary Janes across the Marvel Multiverse are destined to die by exposure to Spidey's semen. We have seen the Earth-616's MJ sleeping with Peter and in Earth-982, Peter and MJ had two children. Are these two Mary Janes going to eventually die?
Spider-Man probably didn't just kill MJ: Other exes, like Black Cat, who is usually Spidey's first sexual partner, or Glory Grant must have also developed cancer.
