Take a sip...
- Whenever Cruella pulls out her tape recorder and says "Memo to myself...".
- Take two if she doesn't use her tape recorder.
- Whenever Cruella yells at Horace and Jasper.
- Whenever Cruella fires someone.
- Whenever Cruella gets Roger's name wrong.
- Take two if she actually gets it right.
- Whenever Cruella calls Anita (or another character) "darling".
- Take one drink if Lucky is voiced by Pamela Adlon in an episode. Two if Debi Mae West is voicing him.
- Whenever Lucky talks about Thunderbolt or is watching Thunderbolt.
- Whenever Cadpig snarks about another character.
- Whenever Cadpig threatens or attacks another character. Two if it's right after she preaches about peace and getting along.
- Whenever Rolly says "Oh, papa!"
- Whenever Rolly eats something.
- Whenever Spot is injured.
- Whenever one of the minor pups (Two-Tone, Tripod, Whizzer, Dipstick, and Patch) show up in the background.
- Take another if they get a speaking role.
- Take three if they have a larger role in the plot.
- Whenever Two-Tone is indecisive about something.
- Whenever Lieutenant Pug demands push-ups from the Bark Brigade. Take another if it's Lucky.
- Whenever Lieutenant Pug brings up "the great cat invasion".
- Whenever Lieutenant Pug blacks out and falls asleep.
- Whenever Roger makes a snipe at Cruella.
- Whenever a Mythology Gag or Continuity Nod is made toward the original animated movie or 1996 live-action movie.
- Whenever an episode title contains a pun. Two drinks if it's dog-related.
- Whenever one of Cruella's family members shows up.
- Whenever there's an animation goof.
- Whenever a reference to another Disney film shows up.
- Whenever Mooch is being a jerk to another character. Two if it's Lucky or Rolly.
- Whenever Swamp Rat scams somebody.
- Whenever Dumpling yells "DADDY!".