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* Creator/HBeamPiper's ''Uller Uprising'' briefly mentions life on the planet Niflheim. It's carbon-based but uses fluorine in place of oxygen. Water is replaced by hydrofluoric acid and carbon dioxide by carbon tetrafluoride. Piper didn't come up with idea - he was presented with an introductory essay by Dr. John D. Clark describing life on both Niflheim and Uller (see entry above under "Silicon").

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* Creator/HBeamPiper's ''Uller Uprising'' ''Literature/UllerUprising'' briefly mentions life on the planet Niflheim. It's carbon-based but uses fluorine in place of oxygen. Water is replaced by hydrofluoric acid and carbon dioxide by carbon tetrafluoride. Piper didn't come up with idea - he was presented with an introductory essay by Dr. John D. Clark describing life on both Niflheim and Uller (see entry above under "Silicon").



* The life forms of the planet Prism in Creator/AlanDeanFoster's novel ''Sentenced to Prism'' use both carbon and silicon in their biology.

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* The life forms of the planet Prism in Creator/AlanDeanFoster's novel ''Sentenced to Prism'' ''Literature/SentencedToPrism'' use both carbon and silicon in their biology.
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* ''Film/{{Evolution}}'' has nitrogen-based life. Since this makes them giant piles of azides, they are literally MadeOfExplodium. Cleverly enough, evolution has turned this into an advantage: extreme heat catalyzes their rapid cellular reproduction and growth. Combined with rapid mutations, this is why they seem to evolve before our eyes, [[EvolutionaryLevels such as a field of them suffocating in our atmosphere, with one able to gasp for life long enough to start producing more offspring already better able to breathe our air, then growing wings and flying away]].

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* ''Film/{{Evolution}}'' ''Film/{{Evolution|2001}}'' has nitrogen-based life. Since this makes them giant piles of azides, they are literally MadeOfExplodium. Cleverly enough, evolution has turned this into an advantage: extreme heat catalyzes their rapid cellular reproduction and growth. Combined with rapid mutations, this is why they seem to evolve before our eyes, [[EvolutionaryLevels such as a field of them suffocating in our atmosphere, with one able to gasp for life long enough to start producing more offspring already better able to breathe our air, then growing wings and flying away]].

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* ''Literature/DragonsEgg'' features the Cheela, made out of the degenerate matter found in neutron stars.



* ''TabletopGame/{{GURPS}}: Space'' has suggestions for hydrogen- and sulfur-based lifeforms as well as silicon-based ones.

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* ''TabletopGame/{{GURPS}}: Space'' has suggestions for hydrogen- life forms based on hydrogen, petrochemicals, ammonia, chlorine, stellar plasma, and sulfur-based lifeforms as well as silicon-based ones.even [[Literature/DragonsEgg degenerate matter]].
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* The Outsiders of Creator/LarryNiven's ''Literature/KnownSpace'' series are effectively bags of cryogenic superfluid helium. Their life functions and intelligence are entirely dictated by the interaction of currents inside their bodies.

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* The Outsiders of Creator/LarryNiven's ''Literature/KnownSpace'' series are effectively bags of cryogenic superfluid helium. Their life functions and intelligence are entirely dictated by the interaction of currents inside their bodies.



** Similarly, the life forms of the planet Prism in Foster's novel ''Sentenced to Prism'' use both carbon and silicon in their biology.

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** Similarly, the * The life forms of the planet Prism in Foster's Creator/AlanDeanFoster's novel ''Sentenced to Prism'' use both carbon and silicon in their biology.
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* A medical examiner studying a Skrull corpse in ''Film/CaptainMarvel'' says while life on Earth is carbon-based, the Skrull is something that's [[NotOfThisEarth not on the periodic table]].

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* A medical examiner studying a Skrull corpse in ''Film/CaptainMarvel'' ''Film/CaptainMarvel2019'' says while life on Earth is carbon-based, the Skrull is something that's [[NotOfThisEarth not on the periodic table]].



* ''Literature/{{Animorphs}}'': While they don't discuss what element they're based on, the Venber in one story are "not carbon-based" as they melt above freezing temperatures. Probably ammonia. It's been speculated that ammonia-based life could exist on extremely cold planets.
* Creator/ArthurCClarke

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* ''Literature/{{Animorphs}}'': While they don't discuss what element they're based on, the Venber in one story are "not carbon-based" -- probably ammonia, as they melt above freezing temperatures. Probably ammonia.temperatures. It's been speculated that ammonia-based life could exist on extremely cold planets.
* Creator/ArthurCClarkeCreator/ArthurCClarke:



** Another story explores the possibility of hydrogen based creatures on the surface of the sun.

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** Another story explores the possibility of hydrogen based hydrogen-based creatures on the surface of the sun.



* Creator/HBeamPiper's ''Uller Uprising'' briefly mentions life on the planet Niflheim. It's carbon-based, but uses fluorine in place of oxygen. Water is replaced by hydrofluoric acid and carbon dioxide by carbon tetrafluoride. Piper didn't come up with idea - he was presented with an introductory essay by Dr. John D. Clark describing life on both Niflheim and Uller (see entry above under "Silicon").

to:

* Creator/HBeamPiper's ''Uller Uprising'' briefly mentions life on the planet Niflheim. It's carbon-based, carbon-based but uses fluorine in place of oxygen. Water is replaced by hydrofluoric acid and carbon dioxide by carbon tetrafluoride. Piper didn't come up with idea - he was presented with an introductory essay by Dr. John D. Clark describing life on both Niflheim and Uller (see entry above under "Silicon").



* ''Literature/TheOsmerianConflict'' gives us the titular Osmerians who are primarily made up of the metal Osmium. However we are never told how the molecule is represented in Osmerian anatomy.

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* ''Literature/TheOsmerianConflict'' gives us the titular Osmerians who are primarily made up of the metal Osmium. However However, we are never told how the molecule is represented in Osmerian anatomy.



* In the ''Literature/HumanxCommonwealth'' novel ''Quofum'', the xenologists who investigate the weird planet's surface are ''floored'' by the presence of multiple biochemical systems - carbon-based, silicon-based, sulfate-based, nitrogen-based, gaseous, etc - existing side by side in the same ecosystems.
** Similarly, the life forms of the planet Prism in Foster's novel ''Sentenced To Prism'' use both carbon and silicon in their biology.

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* In the ''Literature/HumanxCommonwealth'' novel ''Quofum'', the xenologists who investigate the weird planet's surface are ''floored'' by the presence of multiple biochemical systems - -- carbon-based, silicon-based, sulfate-based, nitrogen-based, gaseous, etc - etc. -- existing side by side in the same ecosystems.
** Similarly, the life forms of the planet Prism in Foster's novel ''Sentenced To to Prism'' use both carbon and silicon in their biology.



* ''Series/TheXFiles'' episode featured ammonia-based alien brain worms that rode to Earth on an asteroid in prehistoric times and were hiding out at the North Pole. How they were able to take over the bodies of the human scientists that were trying to study them, despite the fact that not only is their biochemistry obviously incompatible, but being inside a human body for any length of time should have ''melted'' the little bastards is never adequately explained.
* ''Series/DoctorWho''

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* ''Series/TheXFiles'' ''Series/TheXFiles'': The episode featured "[[Recap/TheXFilesS01E08Ice Ice]]" features ammonia-based alien brain worms that rode to Earth on an asteroid in prehistoric times and were are hiding out at the North Pole. How they were It's never adequately explained how they're able to [[PuppeteerParasite take over the bodies of the human scientists that were trying to study them, despite them]], given the fact that not only is their biochemistry [[NoBiochemicalBarriers obviously incompatible, incompatible]], but being inside a human body for any length of time should have ''melted'' the little bastards is never adequately explained.
bastards.
* ''Series/DoctorWho''''Series/DoctorWho'':



** The Raxacoricofallapatorians (the Slitheens' species) are calcium-based. Vinegar was lethally acidic to them.
* ''Series/StargateSG1'' has sulfur-based aliens. The aliens themselves didn't show up as anything more than a picture, their automated probe was xenoforming an earth like planet into something their ecosystem could inhabit.

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** The Raxacoricofallapatorians (the Slitheens' species) (species of the Slitheen, from "[[Recap/DoctorWhoS27E4AliensOfLondon Aliens of London]]" and "[[Recap/DoctorWhoS27E5WorldWarThree World War Three]]") are calcium-based. Vinegar was is lethally acidic to them.
* ''Series/StargateSG1'' has sulfur-based aliens. The aliens themselves didn't show up as anything more than a picture, their automated probe was xenoforming [[HostileTerraforming xenoforming]] an earth like Earth-like planet into something their ecosystem could inhabit.



[[folder:Tabletop [=RPG=]s]]

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[[folder:Tabletop [=RPG=]s]]Games]]
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* A medical examiner studying a Skrull corpse in ''Film/CaptainMarvel'' and says while life on Earth is carbon-based, the Skrull is something that's not on the periodic table.

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* A medical examiner studying a Skrull corpse in ''Film/CaptainMarvel'' and says while life on Earth is carbon-based, the Skrull is something that's [[NotOfThisEarth not on the periodic table.table]].
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* A medical examiner studying a Skrull corpse in ''Film/CaptainMarvel'' and says while life on Earth is carbon-based, the Skrull is something that's not on the periodic table.
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[[folder:ComicBooks]]
* In [[Comicbook/CrisisOnInfiniteEarths Pre-Crisis]] days, [[Comicbook/{{Bizarro}} Bizarros]] looked as if they were made of some kind mineral and were always described as being made of "non-living matter." It's anyone's guess what sort of matter that was, but the implication is that they were not organic.
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** The Raxacoricofallapatorians (the Slitheens' species) are calcium-based.

to:

** The Raxacoricofallapatorians (the Slitheens' species) are calcium-based. Vinegar was lethally acidic to them.
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* Sulfur-oxidizing bacteria exist on Earth. The [[http://en.wikipedia.org/wiki/Purple_sulfur_bacteria purple sulfur bacteria]] are photosynthetic, anaerobic, and are found in hot springs or stagnant water. They do not use water for reduction and thus do not produce oxygen. Instead, they oxidize hydrogen sulfide to produce elemental sulfur which in turn may be oxidized to produce sulfuric acid.

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* Sulfur-oxidizing bacteria exist on Earth. The [[http://en.wikipedia.org/wiki/Purple_sulfur_bacteria purple sulfur bacteria]] are photosynthetic, anaerobic, and are found in hot springs or stagnant water. They do not use water for reduction and thus do not produce oxygen. Instead, they oxidize hydrogen sulfide to produce elemental sulfur which in turn may be oxidized to produce sulfuric acid. That said this is a [[SubvertedTrope Subversion]], as even if they don't breathe oxygen, they're still carbon-based like all other earth organisms.
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For more specific examples of this trope, see SiliconBasedLife.
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!!Other Elements

[[foldercontrol]]

[[folder:Film]]
* ''Film/{{Evolution}}'' has nitrogen-based life. Since this makes them giant piles of azides, they are literally MadeOfExplodium. Cleverly enough, evolution has turned this into an advantage: extreme heat catalyzes their rapid cellular reproduction and growth. Combined with rapid mutations, this is why they seem to evolve before our eyes, [[EvolutionaryLevels such as a field of them suffocating in our atmosphere, with one able to gasp for life long enough to start producing more offspring already better able to breathe our air, then growing wings and flying away]].
[[/folder]]

[[folder:Literature]]
* ''Literature/{{Animorphs}}'': While they don't discuss what element they're based on, the Venber in one story are "not carbon-based" as they melt above freezing temperatures. Probably ammonia. It's been speculated that ammonia-based life could exist on extremely cold planets.
* Creator/ArthurCClarke
** A nineties story references "germanium-based consciousness," albeit as a long-complete AssimilationPlot by previously carbon-based aliens. (Germanium is directly below silicon on the periodic table.)
** The lifeforms on Jupiter in ''[[Literature/TheSpaceOdysseySeries 2010 A Space Odyssey]]'' are hydrogen based.
** Another story explores the possibility of hydrogen based creatures on the surface of the sun.
* In one Creator/IsaacAsimov story, it's mentioned that some of the native bacteria on the Spacer planet Aurora have fluorocarbon rather than hydrocarbon chemistry.
* Creator/HBeamPiper's ''Uller Uprising'' briefly mentions life on the planet Niflheim. It's carbon-based, but uses fluorine in place of oxygen. Water is replaced by hydrofluoric acid and carbon dioxide by carbon tetrafluoride. Piper didn't come up with idea - he was presented with an introductory essay by Dr. John D. Clark describing life on both Niflheim and Uller (see entry above under "Silicon").
* The Outsiders of Creator/LarryNiven's ''Literature/KnownSpace'' series are effectively bags of cryogenic superfluid helium. Their life functions and intelligence are entirely dictated by the interaction of currents inside their bodies.
* ''Literature/TheOsmerianConflict'' gives us the titular Osmerians who are primarily made up of the metal Osmium. However we are never told how the molecule is represented in Osmerian anatomy.
* The Jan in ''Literature/AlienInASmallTown'' are described as having both silicon and carbon in their chemical makeup. They are extremophiles who are most comfortable in Earth's polar regions. Earth's temperate zones are hard for them to endure, and the tropics would kill them.
* In the ''Literature/HumanxCommonwealth'' novel ''Quofum'', the xenologists who investigate the weird planet's surface are ''floored'' by the presence of multiple biochemical systems - carbon-based, silicon-based, sulfate-based, nitrogen-based, gaseous, etc - existing side by side in the same ecosystems.
** Similarly, the life forms of the planet Prism in Foster's novel ''Sentenced To Prism'' use both carbon and silicon in their biology.
[[/folder]]

[[folder:Live-Action TV]]
* ''Series/TheXFiles'' episode featured ammonia-based alien brain worms that rode to Earth on an asteroid in prehistoric times and were hiding out at the North Pole. How they were able to take over the bodies of the human scientists that were trying to study them, despite the fact that not only is their biochemistry obviously incompatible, but being inside a human body for any length of time should have ''melted'' the little bastards is never adequately explained.
* ''Series/DoctorWho''
** The [[Recap/DoctorWhoS6E4TheKrotons Krotons]] are tellurium-based. The story does not mention what would to chemists be the most immediate identifying feature of such biochemistry - that to human noses they would smell so foul that it would be impossible to stay in the same room as them.
** The Raxacoricofallapatorians (the Slitheens' species) are calcium-based.
* ''Series/StargateSG1'' has sulfur-based aliens. The aliens themselves didn't show up as anything more than a picture, their automated probe was xenoforming an earth like planet into something their ecosystem could inhabit.
* One episode of ''Series/TheSarahJaneAdventures'' features a boron-based alien.
[[/folder]]

[[folder:Tabletop [=RPG=]s]]
* ''TabletopGame/{{GURPS}}: Space'' has suggestions for hydrogen- and sulfur-based lifeforms as well as silicon-based ones.
* ''TabletopGame/StarDrive'' uses a page in its ''Alien Compendium'' sourcebook to explain six different classes of biochemistry, based on "liquid medium," "reagent for cellular respiration," and "compounds or elements that can create very complex organic molecules," which correlate well with the GURPS supplement described above. Furthermore, each type is only found on certain classes of planets. These classes are Class 1: "Terran (habitable)," Class 2: "Minimal (minor life support required due to climatic extremes, atmospheric conditions, etc.)," Class 3: "Extreme (major life support required due to intolerable climate or atmosphere)," Class 4: "Space (including asteroids, rings, etc.)," and Class 5: "Jovian (extreme life support required)."
** The series of life are Series 1: Water medium, Oxygen reagent, Carbon structure, Class 1/2 environment; Series 2: Ammonia medium, Hydrogen reagent, Hydrocarbon structure, Class 3 environment; Series 3: Water medium, Chlorine reagent, Carbon structure, Class 2/3 environment; Series 4: Sulfur dioxide medium, Sulfur trioxide reagent, Carbon structure, Class 3 environment; Series 5: Sulfuric acid medium, Oxygen reagent, Silicone structure, Class 3 environment; Series 6: Sulfur medium, Sulfur dioxide reagent, Fluorosilicone structure, Class 3/5 environment; and Series 7: anything that doesn't fit into the biochemistries described above.
* In ''TabletopGame/RocketAge'' the unknown surface of Venus, deep below the mists and incredibly hot, is inhabited by the Triodi, powerful psychic crystalline creatures that feed on the chemical soups that form there. These creatures' corpses are the source of the Venusian''s psychic crystals. They are incredibly territorial and dislike the 'meaty' creatures above them. Thankfully they don't know about other sophonts, yet.
[[/folder]]

[[folder:Video Games]]
* The [[ProudMerchantRace volus]] of ''Franchise/MassEffect'' hail from a planet with an ammonia-based biosphere and a high gravitational field. This means that the volus can't survive in the oxygen/nitrogen atmosphere most other races, including humans, hail from. Volus need to wear high-pressure suits at all times, which not only lets them breathe gasses that are more tolerable to their physiology, but also keeps them from bursting open in a low-pressure atmosphere.
* The planet Freaze from ''VideoGame/{{Meteos}}'' has extremely cold temperatures; -120 degrees F is the highest temperature. Its StarfishAlien inhabitants are more along the lines of of 40-meter tall sentient glaciers than organisms in order to live in such a harsh environment.
[[/folder]]

[[folder:Western Animation]]
* On ''WesternAnimation/TheNewAdventuresOfJonnyQuest'' we have Hardrock. The man of living stone was an ancient human whose body had been changed by radiation into solid carbon.
* The gems seen in ''WesternAnimation/StevenUniverse'' appear to be female humans, [[AmazingTechnicolorPopulation if a bit oddly-colored]], but their true forms are the magical gemstones embedded in their bodies. The rest is a projection made out of HardLight which they can [[FromASingleCell replace]], [[VoluntaryShapeshifting reshape]], or even [[FusionDance combine with others]] as needed. Steven, being a HalfHumanHybrid, is the only exception. Said gemstones come in such wide varieties that only ''some'' of them, such as Peridot and the Quartzes, are literally based on silicon. Ruby and Sapphire are Aluminum-based (although they ''fuse'' into a gem named for a silicate), while Pearl and the Diamonds are technically also carbon-based (though not still not organic in a biological sense).
* A minor recurring character in the later seasons of ''WesternAnimation/{{Futurama}}'' was the Borax Kid, a southern fried-style gambler resembling a man made out of borax minerals.
[[/folder]]

[[folder:Real Life]]
* Sulfur-oxidizing bacteria exist on Earth. The [[http://en.wikipedia.org/wiki/Purple_sulfur_bacteria purple sulfur bacteria]] are photosynthetic, anaerobic, and are found in hot springs or stagnant water. They do not use water for reduction and thus do not produce oxygen. Instead, they oxidize hydrogen sulfide to produce elemental sulfur which in turn may be oxidized to produce sulfuric acid.
* [[http://www.newscientist.com/article/dn20906-lifelike-cells-are-made-of-metal.html In 2011]] it was proven that metal oxides can function in a manner similar to carbon compounds in the formation of life.
[[/folder]]
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