History Main / SuperhumanTransfusion

* {{Invoked|Trope}} in ''Film/TheIncredibleHulk2008'' by Emil Blonsky, who has himself transfused with Bruce Banner's blood in order to get stronger. Interestingly, he was already an experimental SuperSoldier, and Banner's blood interacted with that [[PsychoSerum in a rather unpleasant manner]], causing him to become the Abomination.

[[folder:Film]]
* {{Invoked|Trope}} in ''Film/TheIncredibleHulk2008'' by Emil Blonsky, who has himself transfused with Bruce Banner's blood in order to get stronger. Interestingly, he was already an experimental SuperSoldier, and Banner's blood interacted with that [[PsychoSerum in a rather unpleasant manner]], causing him to become the Abomination.
* Scott from ''Film/Leprechaun3'' gets some of the Leprechaun's blood in a wound, which causes him to begin mutating into a leprechaun.

* ''Film/StarTrekIntoDarkness'': Being injected with Harrison's [[BioAugmentation bio-augmented]] blood temporarily grants others his HealingFactor, although it's not implied to last beyond the initial healing.
* Unlike in ''Webcomic/DarthsAndDroids'', this is {{averted|Trope}} in the canon ''Franchise/StarWars'' universe. According to [[Franchise/StarWarsLegends Expanded Universe]] material, it was attempted on General Grievous by giving him transfusions of Jedi blood during his [[WeCanRebuildHim transformation into a cyborg]], but he never developed any force sensitivity.

* Spitfire of ''ComicBook/TheInvadersMarvel'' gains superpowers from a blood transfusion from the first Human Torch, even though he's an ''android'', because as an ArtificialHuman he has synthetic analogs to all human parts. In fact, this regularly occurrs as he is a universal donor. Aside from its [[FountainOfYouth rejuvenating properties]], it's implied that his blood is a catalyst for latent superhuman abilities; Spitfire is implied to be a latent {{mutant|s}} and Toro, his sidekick, has his dormant mutant genes/[[ComicBook/TheInhumans Inhuman]] [[{{Retcon}} heritage]] partially activated by a transfusion.

* In ''WesternAnimation/YoungJustice'', Beast Boy's {{Animorphism}} (and green skin), instead of coming from SuperSerum as in the comics, is a side-effect of a life-saving blood transfusion from Miss Martian.

A subtrope of SuperEmpowering. See also JustForFun/HowToGiveACharacterSuperPowers.

->'''Anakin:''' What are you doing?
->'''Qui-Gon:''' You're going to need better stats. I'm transferring some of my mini-chlorines to your blood.
->'''Anakin:''' A blood transfusion? What?!
->'''Qui-Gon:''' They'll multiply there and grant you lightning fast reflexes and skill points in driving.
->'''Anakin:''' That's crazy!

* This is ComicBook/{{Deadpool}}'s backstory; his healing factor was derived from Wolverine's blood. Notably, he was one of many [[PlayingWithSyringes test subjects]], most of whom didn't survive, and Deadpool himself suffered some rather severe side effects.

* Spitfire of ''ComicBook/TheInvadersMarvel'' gained superpowers from a blood transfusion from the first Human Torch, even though he was an ''android'', because he was also an ArtificialHuman who had synthetic analogs to all human parts. In fact, this regularly occurred as he was a universal donor. Aside from its [[FountainOfYouth rejuvenating properties]], it's implied his blood is a catalyst for latent superhuman abilities; Spitfire is implied to be a latent {{mutant|s}} and Toro, his sidekick, has his dormant mutant genes/[[ComicBook/TheInhumans Inhuman]] [[{{Retcon}} heritage]] partially activated by a transfusion.

* In one ''[[ComicBook/RatMan1989 Rat-Man]]'' story, the protagonist got Franchise/SpiderMan's powers this way... and being an incompetent {{Jerkass}} he proceeded to abuse the hell out of them while acting as a jerk. Luckily it turned out to be [[AllJustADream Spider-Man's coma dream]], and when he awoke it turned out that ''he'' got a transfusion from Rat-Man... and thus got his infected with his bad luck.
* The ''ComicBook/SavageDragon'' once let his blood be used in an attempt to cure a friend's AIDS. It seemed to work at first-- restoring him to full health, making him stronger, even giving him green skin and a fin-- but within minutes, he exploded. Years later, after [[TheSyndicate The Vicious Circle]] steals a supply of his blood from the hospital, their {{Evil Genius}}es figure out a way to keep people alive much longer after being injected. But it turns out that regular doses are necessary in order to keep delaying the explosion, so when Dragon-blood-enhanced supercriminals get arrested, they end up exploding while in custody.
* This is ComicBook/SheHulk's origin. She needed a blood transfusion and [[ComicBook/TheIncredibleHulk Bruce]] was on hand; afterwards, she was permanently changed into a hulk, although she retained her personality and intellect. It later [[{{Retcon}} turned out]] that the Hulk's drastic change in personality is caused by a multiple personality disorder which is exacerbated by his transformation. She-Hulk's personality ''does'' change, but instead of going into an UnstoppableRage like Bruce does, she just gets sassier and more confident. She also doesn't have the insane number of alternate transformations that Bruce does.
* {{Inverted|Trope}} early on in ''ComicBook/SpiderMan'' when Peter gave blood to save Aunt May. Neither of them got much out of it -- Peter was too woozy to fight for much of the issue, and his radioactive blood nearly killed Aunt May later on, sparking another "race to find a cure" story.

** In ''ComicBook/{{Superman}}'' #6 1940, Clark Kent opens his own vein to transfuse an injured Lois Lane; not only is she healed of injuries, but the doctor remarks that "his blood conforms to all four types".

** This actually ''did'' happen in ''ComicBook/ActionComics'' February 1965. [[ComicBook/{{Supergirl}} Linda Danvers]] donates blood (using Red Kryptonite to de-super her arm for this purpose). Classmate Debbie has a head injury and the blood is used in her surgery. However her brain damage makes her EVIL, so now an evil Supergirl flies around freeing crooks and baffling police. Linda catches on when Deb tells her she's read an entire mystery novel in a single night, because [[RealLifeSuperPowers altogether human speed readers]] apparently don't exist. Fortunately super powers gained this way last only 48 hours.
** In a [[UsefulNotes/TheBronzeAgeOfComicBooks Bronze Age]] Superman story, Clark Kent, Lois Lane, and Lana Lang were exposed to alien microbes from a vial that Lana accidentally dropped and broke -- the same alien microbes that infected Clark's adopted parents, leading to their deaths prior to his becoming Superman. However, Superman discovers that his Kryptonian immunity system was able to fight off the microbes when he was exposed to them, thus creating a vaccine that he passed on to both Lois and Lana through a blood transfusion that cured them of the microbe infection.

* Infamously, the Creator/MarvelComics [[UsefulNotes/TheGoldenAgeOfComicBooks Golden Age]] hero [[AtrociousAlias The Whizzer]] gained his SuperSpeed powers from ''a blood transfusion from a mongoose.''
* ''Comicbook/XMen'' character Jonathan "Jono" Starsmore aka Chamber lost his powers during M-day. This was very bad for him since the first manifestation of his powers destroyed part of his body including some vital organs, and his power was what kept him alive. However, Jono's family the Starsmores were also a part of Clan Akkaba, descendants and followers of [[Characters/MarvelComicsApocalypse Apocalypse]]. Clan Akkaba, hoping to convince Jono to join them, gave him a transfusion of Apocalypse's blood. This healed his body and gave him some of Apocalypse's features such as gray skin, red eyes, and blue lips.

* {{Invoked|Trope}} in ''Film/TheIncredibleHulk2008'' by Emil Blonsky, who has himself transfused with Bruce Banner's blood in order to get stronger. Interestingly, he was already an experimental SuperSoldier, and Banner's blood interacted with that in a rather unpleasant manner, causing him to become the Abomination.

* When WesternAnimation/{{Megamind}} finally succeeds at removing his WorthyOpponent Metro Man and [[AndThenWhat is left with nothing to do]], he ends up creating a new hero to fight by accidentally injecting some random joe off the street with Metro Man's DNA. [[spoiler:That really [[BewareTheSuperman didn't work out]], though.]]

* Unlike in ''Webcomic/DarthsAndDroids'', this is averted in the canon ''Franchise/StarWars'' universe. According to [[Franchise/StarWarsLegends Expanded Universe]] material, it was attempted on General Grievous by giving him transfusions of Jedi blood during his transformation into a cyborg, but he never developed any force sensitivity.

[[folder:Live Action TV]]
* ''Series/TheFortyFourHundred'' had an {{inver|tedTrope}}sion. Isabel, the first child born to two returnees, produces pure [[SuperSerum promycin.]] When all the other returnees are suffering from an anti-promycin drug, her blood cures Shawn who went on to use his own healing powers on everyone else.
* ''Series/{{Charmed|1998}}'':

* The TV movie ''[[http://www.imdb.com/title/tt0109589/ Deep Red]]''. It has a girl whose {{nanomachine|s}}-infused blood rejuvenates the recipient and grants VoluntaryShapeshifting. In a twist, the power only lasts for a limited time, and regular transfusions are needed for people to sustain them. It's because of this that the bad guy, who has some of her blood in his system, is after her.

* This is what the 1969-71 series ''Series/TheImmortal'' was all about. The hero (Chris George)'s is a race car driver whose blood makes him immune to all diseases. An ailing bazillionaire wants him for transfusions, and is determined to [[SuperhumanTrafficking capture and enslave him]] to ensure a lifelond supply of blood.
* In ''Series/{{Misfits}}'', Nikki inadvertently gains the ability to teleport by a [[BadassTransplant heart transplant]] from Ollie. She never learned to control it though.
* ''Series/TheOuterLimits1995'': In the episode "[[Recap/TheOuterLimits1995S3E4LastSupper Last Supper]]", a MadScientist is pursuing an immortal woman so he can collect her unique blood and inject it into himself to both heal his own wounds and reverse his aging. [[spoiler:He does manage to get hold of it but miscalculates the stuff's potency, eventually [[DeathByDeaging shriveling up into a pool of cells]].]]
* In ''Series/StargateUniverse'', Chloe Armstrong was able to cure lieutenant Scott with blood transfusion in the episode "[[Recap/StargateUniverseS2E5Cloverdale Cloverdale]]".

* In the final episode of ''Series/TorchwoodMiracleDay'', [[spoiler:Rex has a transfusion of Jack's blood in order to sneak some into the Blessing site. At the end of the episode, it's revealed that doing so has granted him Jack's immortality.]]

* In ''VideoGame/FreedomForce'', this is how Liberty Lad got his powers, Minuteman gave him a blood transfusion after his RecklessSidekick behavior got him shot.
* In ''VideoGame/IronTwilight'', you get closer to the end of the game and you find out Felipe's past. Felipe got a blood transfusion from a monster guitar player that got killed in a car accident. Felipe accidentally fell in the puddle of the musical artist's blood, leaving some of the blood to get drained into Felipe's wounds. It was then, Felipe got excellent guitar playing skills and used them to dramatically rank up in the charts. However, he ranked down to the lowest level after Jack killed him in the game's climax (if you make Jack choose to).

* In ''VideoGame/OperationDarkness'', a [[OurWerewolvesAreDifferent Werewolf]] giving his blood to someone changes them and gives them some kind of power. If they survive.

[[folder:Web Comics]]

* There's a ''Webcomic/PennyArcade'' comic where, after a car-crash, Gabe and Tycho end up in the hospital and get blood-transfusions. Gabe ends up getting blood donated by Franchise/SpiderMan, and immediately develops web-shooting abilities[[note]]Taking this into account, he most likely got his transfusion from the ''Creator/SamRaimi'' [[Film/SpiderManTrilogy Spider-Man]] due to his organic webbing, as most Spider-Men ''need'' a web shooter for web slinging.[[/note]], much to his joy. Tycho got [[ButtMonkey monkey-blood]].

* Creator/TexAvery plays it for laughs (natch) in the Creator/WalterLantz cartoon "WesternAnimation/CrazyMixedUpPup". A man and his dog are run over and the paramedics give them transfusions, only the man gets canine plasma and the dog gets human plasma, resulting in [[DelusionsOfDoghood a man acting like a dog and vice versa]].

* The plot of one ''WesternAnimation/TeenTitansGo'' episode has the Titans having to deal with their out of control animal urges because they have Beast Boy's blood in them... after he himself couldn't be bothered to control his own and caused the mess in the first place. When they can't it falls onto Beast Boy to deal with 4 rowdy animals.
* In ''WesternAnimation/YoungJustice'', Beast Boy's {{Animorphism}} (and green skin), instead of coming from SuperSerum as in the comics, was a side-effect of a life-saving blood transfusion from Miss Martian.

* In one ''ComicBook/{{Rat-Man}}'' story, the protagonist got Franchise/SpiderMan's powers this way... and being an incompetent {{Jerkass}} he proceeded to abuse the hell out of them while acting as a jerk. Luckily it turned out to be [[AllJustADream Spider-Man's coma dream]], and when he awoke it turned out that ''he'' got a transfusion from Rat-Man... and thus got his infected with his bad luck.

John has one or more StockSuperpowers of the genetic and/or magical variety. He may have gained them from birth thanks to SuperpowerfulGenetics, [[GeneticEngineeringIsTheNewNuke genetic experimentation]], or after conception thanks to SuperSerum, a MassSuperEmpoweringEvent or a DisposableSuperheroMaker. Alternately, he has mystic powers in a setting where ThePowerOfBlood and BloodMagic are very real, so his blood contains a measure of his magic. In short, his powers course through his blood in a very real sense.

John has one or more StockSuperpowers of the genetic and/or magical variety. He may have gained them from birth thanks to SuperpowerfulGenetics, [[DesignerBabies genetic experimentation]], or after conception thanks to SuperSerum, a MassSuperEmpoweringEvent or a DisposableSuperheroMaker. Alternately, he has mystic powers in a setting where ThePowerOfBlood and BloodMagic are very real, so his blood contains a measure of his magic. In short, his powers course through his blood in a very real sense.

Suddenly, his friend Jack [[FriendlyTarget gets shot by one of his enemies,]] and has only minutes to live before even his [[OverdrawnAtTheBloodbank copious blood supply runs out]]! Just by luck, Jack and John are the same blood type, and a quick emergency transfusion ensues... which results in an EmergencyTransformation. Thanks to the blood-borne nature of John's powers, Jack now has those same abilities! They might be temporary and last only as long as John's blood is in his system, or they may trigger a similar reaction in Jack's body and give him permanent (and potentially different) powers.

It bears mentioning that in RealLife blood transfusions in no way transfer the donor's genes into the recipient's DNA. The red and white blood cells last only a few months before dying without leaving a trace. If John's powers are biological/genetic/chemical in nature, and/or {{Phlebotinum}} is involved, Jack getting these powers is often justified by TheProfessor explaining that the donation triggered dormant super-genes in Jack, or actually ''did'' somehow [[ViralTransformation overwrite parts of his genome]]. If John's powers are magical in nature, then the reason Jack gets similar powers may have to do with BloodMagic. In these cases "John" might not even be the same species as Jack, such as dragon or vampire blood [[note]]of the mystical, non [[ViralTransformation viral based types]][[/note]], endowing the imbiber with power. If John's powers are from a [[TheSymbiote (symbiotic) virus]] then it reasonably would be able to transfer via blood transfusion, though you can probably count characters with these powers on one hand.

* ''Anime/BNABrandNewAnimal'' eventually reveals that Michiru [[spoiler:and Nazuna]] were transformed into beastmen with unusual shapeshifting abilities after an accidental transfusion of modified beastman blood [[spoiler: that was used in Sylvasta Pharmaceutical's genetic experiments. It later turns out that Michuru and Nazuna's blood can cure the Nirvasil syndrome ravaging Anima City, without suppressing the Beast Factor like Sylvasta's "vaccine".]]

*** Tsukune receives a few {{Emergency Transformation}}s from Moka this way, usually as a result of him [[TakingTheBullet protecting his friends]]. Eventually, it becomes permanent; he gets a holy lock from the headmaster, which holds back the feral ghoul in his blood. [[spoiler:At the end of the series, he tears off the lock in an act of desperation and discovers it wasn't just holding the ghoul back, it was actually adapting him to the vampire blood; he goes into his junior year a full-blood vampire.]]
*** It's revealed near the end of Season I that [[spoiler:the leader of the Anti-Schoolers, Hokuto, was also [[ShadowArchetype a human who attended Yokai Academy, and similarly received a life-changing infusion of the same sort]].]]
** Season II reveals this also works in specific monster-to-monster cases. [[spoiler:Certain vampires known as 'first ancestors' have abnormally powerful blood, which can only be given to other vampires (or taken from them) by the reception of the first ancestor's blood. When Moka was stillborn, her mother Akasha gave her first ancestor blood to heal Moka, with the side effect of them sharing the first ancestor's power. A fatal blow during the final volume provokes the above-mentioned desperation act as Tsukune returns Moka's favour and gives her blood back to heal her, resulting in the two of ''them'' sharing first ancestor power.]]

* The main character of ''Manga/TokyoGhoul'' was transformed into a human/ghoul hybrid due to receiving an organ transplant from a ghoul.

* This is ComicBook/{{Deadpool}}'s backstory; his healing factor was derived from Wolverine's blood. Notably, he was one of many test subjects, most of whom didn't survive, and Deadpool himself suffered some rather severe side effects.

* Spitfire of ''ComicBook/TheInvadersMarvel'' gained superpowers from a blood transfusion from the first ComicBook/HumanTorch, although he was an ''android'', because he was also a RidiculouslyHumanRobot who had synthetic analogs to all human parts. In fact, this regularly occurred as he was a universal donor. Aside from its [[FountainOfYouth rejuvenative properties]], it's implied his blood is a catalyst for latent superhuman abilities; Spitfire is implied to be a latent mutant and Toro, his sidekick, has his dormant Inhuman heritage partially activated by a transfusion.
* In ''ComicBook/PS238'' Tyler is cured of an alien virus via a blood transfusion from Julie to briefly give him her super-health, but it has to be removed before the cells started attacking his own.
* In one ''ComicBook/{{Rat-Man}}'' story, the protagonist got Spider-Man's powers this way... And being an incompetent {{Jerkass}} he proceeded to abuse the hell out of them while acting as a jerk. Luckily it turned out to be [[AllJustADream Spider-Man's coma dream]], and when he awoke it turned out that ''he'' got a transfusion from Rat-Man... And thus got his infected with his bad luck.
* The ''ComicBook/SavageDragon'' once let his blood be used in an attempt to cure a friend's AIDS. It seemed to work at first-- restoring him to full health, making him stronger, even giving him green skin and a fin-- but within minutes, he exploded. Years later, after [[TheSyndicate The Vicious Circle]] steals a supply of his blood from the hospital, their EvilGenius[=es=] figure out a way to keep people alive much longer after being injected. But it turns out that regular doses are necessary in order to keep delaying the explosion, so when Dragon-blood-enhanced supercriminals get arrested, they end up exploding while in custody.
* This is ComicBook/SheHulk's origin. She needed a blood transfusion and [[ComicBook/IncredibleHulk Bruce]] was on hand; afterwards, she was permanently changed into a hulk, although she retained her personality and intellect. It later [[{{Retcon}} turned out]] that the Hulk's drastic change in personality is caused by a multiple personality disorder which is exacerbated by his transformation. She-Hulk's personality ''does'' change, but instead of [[UnstoppableRage HULK SMASH]]!, she just gets sassier and more confident. She also doesn't have the insane number of alternate transformations that Bruce does.
* Inverted early on in ''ComicBook/SpiderMan'' when Peter gave blood to save Aunt May. Neither of them got much out of it -- Peter was too woozy to fight for much of the issue, and his radioactive blood nearly killed Aunt May later on, sparking another "race to find a cure" story.
** ''Comicbook/SpiderGeddon'' shows us one alternate universe where Peter managed to give blood to Uncle Ben, saving his life and making them a Spider-Man duo. (Peter also happens to be about 13, essentially making him a KidSidekick.)

** In ''ComicBook/{{Superman}}'' #6 1940 Clark Kent opens his own vein to transfuse an injured Lois Lane; not only is she healed of injuries, but Siegel has the Doctor remark "incredible his blood conforms to all four types".
** In a GoldenAge story, Lois Lane [[AllJustADream dreams]] she gets a blood transfusion from Superman and gains superpowers, becoming Superwoman.
** This actually ''did'' happen in ''Action'' February 1965. Linda Danvers donates blood (using Red Kryptonite to de-super her arm for this purpose). Classmate Debbie has a head injury and the blood is used in her surgery. However her brain damage makes her EVIL, so now an evil Supergirl flies around freeing crooks and baffling police. Linda catches on when Deb tells her she's read an entire mystery novel in a single night, because [[RealLifeSuperPowers altogether human speed readers]] apparently don't exist. Fortunately super powers gained this way last only 48 hours.
** In a Bronze Age Superman story, Clark Kent, Lois Lane, and Lana Lang were exposed to alien microbes from a vial that Lana accidentally dropped and broke -- the same alien microbes that infected Clark's adopted parents, leading to their deaths prior to his becoming Superman. However, Superman discovers that his Kryptonian immunity system was able to fight off the microbes when he was exposed to them, thus creating a vaccine that he passed on to both Lois and Lana through a blood transfusion that cured them of the microbe infection.
* During the first arc of ''ComicBook/YoungAvengers'', Patriot claims that this is how he got his powers: his grandfather, ComicBook/CaptainAmerica's supersoldier prototype, gave him a blood transfusion. It turns out be a lie (Patriot was addicted to a drug that gave super-powers), but then he [[TakingTheBullet takes a shot from a Kree blaster]] for Cap. When he gets to the hospital after the battle, Cap is all set for this, except "the ''other'' super-soldier beat you to it."
* Infamously, Golden Age hero [[AtrociousAlias The Whizzer]] gained his SuperSpeed powers from ''a blood transfusion from a mongoose.''
* ''Comicbook/XMen'' character Jonothan "Jono" Starsmore aka Chamber lost his powers during M-day. This was very bad for him since the first manifestation of his powers destroyed part of his body including some vital organs, and his power was what kept him alive. However, Jono's family the Starsmores were also a part of Clan Akkaba, descendants and followers of Comicbook/{{Apocalypse}}. Clan Akkaba, hoping to convince Jono to join them, gave him a transfusion of Apocalypse's blood. This healed his body and gave him some of Apocalypse's features such as gray skin, red eyes, and blue lips.

* Invoked in ''Film/TheIncredibleHulk'' by Emil Blonsky, who has himself transfused with Bruce Banner's blood in order to get stronger. Interestingly, he was already an experimental super soldier, and Banner's blood interacted with that in a rather unpleasant manner, causing him to become the Abomination.
* Scott from ''Film/{{Leprechaun 3}}'' gets some of the Leprechaun's blood in a wound, which causes him to begin mutating into a leprechaun.
* When WesternAnimation/{{Megamind}} finally succeeds at removing his WorthyOpponent Metro Man and is left with nothing to do, he ends up [[CreateYourOwnVillain creating a new hero]] to fight by accidentally injecting [[{{Everyman}} some random joe off the street]] with Metro Man's DNA. [[spoiler:That really [[BewareTheSuperman didn't work out]], though.]]
* ''Film/StarTrekIntoDarkness'': Being injected with Harrison's bio-augmented blood temporarily grants others his HealingFactor, although it's not implied to last beyond the initial healing.
* Unlike in ''Webcomic/DarthsAndDroids'', this is averted in the canon ''Franchise/StarWars'' universe. According to ExpandedUniverse material, it was attempted on General Grievous by giving him transfusions of Jedi blood during his transformation into a cyborg, but he never developed any force sensitivity.

* WordOfGod from Rick Riordan, writer of the ''Literature/TheCampHalfBloodSeries'', confirms that this is not the case in his universe. You cannot gain the powers of Percy Jackson from a transfusion of his blood.
* Averted in ''Literature/TheChroniclesOfAmber'': Corwin states that while he can accept any blood type, ordinary humans ''really shouldn't'' receive a transfusion of his blood.
* Downplayed in ''Literature/{{Dragaera}}'' when Morrolan e'Drien receives blood stolen from a PhysicalGod. At the time, it allows him to escape the [[EldritchLocation Paths of the Dead]], though he has to do the footwork himself. When he learns [[DangerousForbiddenTechnique Elder Sorcery]], the blood helps him manipulate the [[EntropyAndChaosMagic raw chaos]] involved without getting liquefied.

* In the webserial ''Literature/HereticalEdge'' this is how Natural Heretics are created, and the only way to make Heretics before Hieronymus Bosch invented the Heretical Edge. A Natural Heretic gains all the abilities of the Stranger which bled on them, but it takes a while for the powers to grow into their full potential.

* ''Series/TheFortyFourHundred'' had an inversion. Isabel, the first child born to two returnees, produces pure [[SuperSerum Promycin.]] When all the other returnees are suffering from an anti-promycin drug, her blood cures Shawn who went on to use his own healing powers on everyone else.

** Crossing mortal blood with a magical creature's come back in the episode "[[Recap/CharmedS8E9HulkusPocus Hulkus Pocus]]" where it creates [[TheVirus a deadly virus]].

* The TV movie ''[[http://www.imdb.com/title/tt0109589/ Deep Red.]]'' It has a girl whose blood rejuvenates the recipient and grants VoluntaryShapeShifting. In a twist, the power only lasts for a limited time, and regular transfusions are needed for people to sustain them. It's because of this that the bad guy, who has some of her blood in his system, is after her.
* In ''Series/{{Heroes}}'' Claire's blood can be used to heal other people through transfusion.
* This is what the 1969-71 series ''Series/TheImmortal'' was all about. The hero (Chris George)'s is a race car driver whose blood makes him immune to all diseases. An ailing bazillionaire wants him for transfusions. This quickly turned into a replay of ''Series/TheFugitive'', but did have its moments.
* In ''Series/{{Misfits}}'', Nikki inadvertently gains the ability to teleport by a heart transplant from Ollie. She never learned to control it though.
* ''Series/TheOuterLimits1995'': In the episode "[[Recap/TheOuterLimits1995S3E4LastSupper Last Supper]]", a MadScientist is pursuing an immortal woman so he can collect her unique blood and inject it into himself to both heal his own wounds and reverse his aging. [[spoiler:He does manage to get hold of it but miscalculates the stuff's potency, eventually [[DeathByDeaging shrivelling up into a pool of cells]].]]
* In ''Series/StargateUniverse'', Chloe Armstrong was able to cure lieutenant Scott with blood transfusion in episode "Cloverdale".

* In the final episode of ''Series/TorchwoodMiracleDay'': [[spoiler: Rex has a transfusion of Jack's blood in order to sneak some into the Blessing site. At the end of the episode, it's revealed that doing so has granted him Jack's immortality.]]

* ''TabletopGame/VampireTheMasquerade'' borrows Anne Rice's method of vampire creation, called "the Embrace". In this case draining the mortal's blood is imperative to transform them into a walking corpse, otherwise they temporarily develop some vampire powers as a ghoul. Vampire blood can be addictive to mortals, and feeding off the same vampire three times binds them to that vampire.

* There's a ''Webcomic/PennyArcade'' comic where, after a car-crash, Gabe and Tycho end up in the hospital and get blood-transfusions. Gabe ends up getting blood donated by Franchise/SpiderMan, and immediately develops web-shooting abilities[[note]]Taking this into account, he most likely got his transfusion from the ''Creator/SamRaimi'' [[Film/SpiderManTrilogy Spider Man]] due to his organic webbing. As most Spider Men ''need'' a web shooter for web slinging.[[/note]], much to his joy. Tycho got [[ButtMonkey monkey-blood]].

* In ''Literature/TheSecretsOfTheImmortalNicholasFlamel'', the vampire Scathach gave UsefulNotes/JoanOfArc an EmergencyTransfusion of her own blood after rescuing her from being burned at the stake. It didn't turn her into a full vampire, but it did make her immortal.

* ''{{Manga/Coppelion}}'' has Aether, an injected medicine derived from the [[RadiationImmuneMutants Coppelions]]' blood that [[FantasticRadiatonShielding grants temporary radiation immunity]] and enhanced healing. Direct transfusions may not have the same effect, since the Medical Team called a helicopter carrying more Aether instead of attempting a transfusion when short on time.

* ''Anime/BNABrandNewAnimal'' eventually reveals that Michiru [[spoiler: and Nazuna]] were transformed into beastmen with unusual shapeshifting abilities after an accidental transfusion of modified beastman blood [[spoiler: that was used in Sylvasta Pharmaceutical's genetic experiments. It later turns out that Michuru and Nazuna's blood can cure the Nirvasil syndrome ravaging Anima City, without suppressing the Beast Factor like Sylvasta's "vaccine".]]
* ''{{Manga/Coppelion}}'' has Aether, an injected medicine derived from the Coppelions' blood that grants temporary radiation immunity and enhanced healing. Direct transfusions may not have the same effect, since the Medical Team called a helicopter carrying more Aether instead of attempting a transfusion when short on time.

* ''Manga/RosarioToVampire''

* One of the early ''Liturature/HankTheCowdog'' books includes a silly song about an elderly cowboy who has his youth restored by a doctor replacing all the blood in his body, but then starts acting crazy and getting into trouble. It turns out the doctor accidentally gave him diesel instead of blood.

* ''Anime/BNABrandNewAnimal'' eventually reveals that Michiru [[spoiler: and Nazuna]] were transformed into beastmen with unusual shapeshifting abilities after an accidental transfusion of beastman blood [[spoiler: that was used in Sylvasta Pharmaceutical's genetic experiments. It later turns out that Michuru and Nazuna's blood can cure the Nirvasil syndrome ravaging Anima City, without suppressing the Beast Factor like Sylvasta's "vaccine".]]

** In a Bronze Age Superman story, Clark Kent, Lois Lane, and Lana Lang were exposed to alien microbes from a vial that Lana accidentally dropped and broke -- the same alien microbes that infected Clark's adopted parents, leading to their deaths prior to his becoming Superman. However, Superman discovers that his Kryptonian immunity system was able to fight off the microbes when he was exposed to them, thus creating a vaccine that he passed onto both Lois and Lana through a blood transfusion that cured them of the microbe infection.

* Spitfire of ''ComicBook/TheInvadersComicBook'' gained superpowers from a blood transfusion from the first ComicBook/HumanTorch, although he was an ''android'', because he was also a RidiculouslyHumanRobot who had synthetic analogs to all human parts. In fact, this regularly occurred as he was a universal donor. Aside from its [[FountainOfYouth rejuvenative properties]], it's implied his blood is a catalyst for latent superhuman abilities; Spitfire is implied to be a latent mutant and Toro, his sidekick, has his dormant Inhuman heritage partially activated by a transfusion.

* This is ComicBook/SheHulk's origin. She needed a blood transfusion and [[Comicbook/IncredibleHulk Bruce]] was on hand, afterwards she was permanently changed into a hulk, albeit she retained her personality and intellect. It later [[{{Retcon}} turned out]] that the Hulk's drastic change in personality is caused by a multiple personality disorder which is exacerbated by his transformation. She-Hulk's personality ''does'' change, but instead of [[UnstoppableRage HULK SMASH]]!, she just gets sassier and more confident. She also doesn't have the insane number of alternate transformations that Bruce does.

* Spitfire of ''ComicBook/TheInvaders'' (Marvel Comics) gained superpowers from a blood transfusion from the first Human Torch. I'm not sure how that worked, given that the first Human Torch was an ''android''.
** He was a RidiculouslyHumanRobot who had synthetic analogs to all human parts. In fact, this regularly occurred as he was a universal donor. Aside from its [[FountainOfYouth rejuvenative properties]], it's implied his blood is a catalyst for latent superhuman abilities; Spitfire is implied to be a latent mutant and Toro, his sidekick, has his dormant Inhuman heritage partially activated by a transfusion.

* There's a ''Webcomic/PennyArcade'' comic where, after a car-crash, Gabe and Tycho end up in the hospital and get blood-transfusions. Gabe ends up getting blood donated by Franchise/SpiderMan, and immediately develops web-shooting abilities, much to his joy. Tycho got [[ButtMonkey monkey-blood]].

* ''Series/TheOuterLimits1995'': In the episode "[[Recap/TheOuterLimits1995S3E4LastSupper Last Supper]]", a MadScientist is pursuing an immortal woman so he can collect her unique blood and inject it into himself to both heal his own wounds and reverse his aging. [[spoiler:He does manage to get hold of it but miscalculates the stuff's potency, eventually shriveling up into a pool of cells.]]

* In the manga ''Manga/WolfGuyWolfenCrest'', Akira gives blood to Chiba after Haguro nearly kills him, and Chiba is healed by it and becomes a werewolf--and crazy, with the ability to change at will into some mutated-looking wolf-beast, unlike Akira's transformation. So, not a completely identical transference of abilities, but Akira didn't realize his powers would transfer at all.

* ''{{Manga/Coppelion}}'' has Aether, an injected medicine derived from the Coppelions' blood that grants temporary radiation immunity and enhanced healing. Direct transfusions may not have the same effect, since the Medical Team called a helicopter carrying more Aether instead of attempting a transfusion when short on time.
* In ''Anime/BloodPlus'' Chiropteran Chevaliers are produced by draining a human male's blood and giving him a bit of a Queen's blood. Both of Saya's Chevaliers were created by EmergencyTransformation of someone she cared about, while Diva tended to stab people.
* ''Anime/BNABrandNewAnimal'' eventually reveals that Michiru [[spoiler: and Nazuna]] were transformed into beastmen with unusual shapeshifting abilities after an accidental transfusion of beastman blood [[spoiler: that was used in Sylvasta Pharmaceutical's genetic experiments. It later turns out that Michuru and Nazuna's blood can cure the Nirvasil syndrome ravaging Anima City, without suppressing the Beast Factor like Sylvasta's "vaccine".]]

* Inverted early on in ''ComicBook/SpiderMan'' when Peter gave blood to save Aunt May. Neither of them got much out of it - Peter was too woozy to fight for much of the issue, and his radioactive blood nearly killed Aunt May later on, sparking another "race to find a cure" story.
** ''Comicbook/SpiderGeddon'' shows us one alternate universe where Peter managed to give blood to Uncle Ben, saving his life and making them a Spider-Man duo. (Peter also happens to be about 13, essentially making him a KidSidekick.)
* This is ComicBook/{{Deadpool}}'s backstory; his healing factor was derived from Wolverine's blood. Notably, he was one of many test subjects, most of whom didn't survive, and Deadpool himself suffered some rather severe side effects.
* The ''ComicBook/SavageDragon'' once let his blood be used in an attempt to cure a friend's AIDS. It seemed to work at first-- restoring him to full health, making him stronger, even giving him green skin and a fin-- but within minutes, he exploded. Years later, after [[TheSyndicate The Vicious Circle]] steals a supply of his blood from the hospital, their EvilGenius[=es=] figure out a way to keep people alive much longer after being injected. But it turns out that regular doses are necessary in order to keep delaying the explosion, so when Dragon-blood-enhanced supercriminals get arrested, they end up exploding while in custody.
* In ''ComicBook/PS238'' Tyler is cured of an alien virus via a blood transfusion from Julie to briefly give him her super-health, but it has to be removed before the cells started attacking his own.

* In one ''ComicBook/{{Rat-Man}}'' story, the protagonist got Spider-Man's powers this way... And being an incompetent {{Jerkass}} he proceeded to abuse the hell out of them while acting as a jerk. Luckily it turned out to be [[AllJustADream Spider-Man's coma dream]], and when he awoke it turned out that ''he'' got a transfusion from Rat-Man... And thus got his infected with his bad luck.

* Scott from ''Film/{{Leprechaun 3}}'' gets some of the Leprechaun's blood in a wound, which causes him to begin mutating into a leprechaun.

* Invoked in ''Film/TheIncredibleHulk'' by Emil Blonsky, who has himself transfused with Bruce Banner's blood in order to get stronger. Interestingly, he was already an experimental super soldier, and Banner's blood interacted with that in a rather unpleasant manner, causing him to become the Abomination.

* In Creator/AnneRice's ''Literature/TheVampireChronicles'' this is how new vampires are created, with an existing vampire and a human slurping blood from each other with none-too-subtle erotic overtones.

* Averted in ''Literature/TheChroniclesOfAmber'': Corwin states that while he can accept any blood type, ordinary humans ''really shouldn't'' receive a transfusion of his blood.
* WordOfGod from Rick Riordan, writer of the ''Literature/TheCampHalfBloodSeries'', confirms that this is not the case in his universe. You cannot gain the powers of Percy Jackson from a transfusion of his blood.

* The TV movie ''[[http://www.imdb.com/title/tt0109589/ Deep Red.]]'' It has a girl whose blood rejuvenates the recipient and grants VoluntaryShapeShifting. In a twist, the power only lasts for a limited time, and regular transfusions are needed for people to sustain them. It's because of this that the bad guy, who has some of her blood in his system, is after her.
* In ''Series/StargateUniverse'', Chloe Armstrong was able to cure lieutenant Scott with blood transfusion in episode "Cloverdale".

* ''Series/{{Charmed|1998}}'':
** In the episode "[[Recap/CharmedS2E20AstralMonkey Astral Monkey]]", Dr. Williamson is experimenting with the Charmed Ones' blood (long story, but he believes it could be the key to a "universal antibody") and unintentionally gives himself and his test subjects (three monkeys) their collective powers (he injected the monkeys with a mix of their blood, and they injected him). Unfortunately, mortals can't properly handle that kind of power, and it starts warping his body and mind; he "does good and saves innocents" by killing criminals and harvesting their organs for those that need them.
** Crossing mortal blood with a magical creature's come back in the episode "[[Recap/CharmedS8E9HulkusPocus Hulkus Pocus]]" where it creates [[TheVirus a deadly virus]].
* This is what the 1969-71 series ''Series/TheImmortal'' was all about. The hero (Chris George)'s is a race car driver whose blood makes him immune to all diseases. An ailing bazillionaire wants him for transfusions. This quickly turned into a replay of ''Series/TheFugitive'', but did have its moments.
* The Special Children in ''Series/{{Supernatural}}'' gain psychic powers after the Yellow-Eyed Demon feeds them his blood at 6 months of age.
* ''Series/TheOuterLimits1995'': In the episode "[[Recap/TheOuterLimits1995S3E4LastSupper Last Supper]]", a MadScientist is pursuing an immortal woman so he can collect her unique blood and inject it into himself to both heal his own wounds and reverse his aging. [[spoiler:He does manage to get hold of it but miscalculates the stuff's potency, eventually shriveling up into a pool of cells.]]

* In ''VideoGame/OperationDarkness'', a [[OurWerewolvesAreDifferent Werewolf]] giving his blood to someone changes them and gives them some kind of power. If they survive.

* In ''VideoGame/IronTwilight'', you get closer to the end of the game and you find out Felipe's past. Felipe got a blood transfusion from a monster guitar player that got killed in a car accident. Felipe accidentally fell in the puddle of the musical artist's blood, leaving some of the blood to get drained into Felipe's wounds. It was then, Felipe got excellent guitar playing skills and used them to dramatically rank up in the charts. However, he ranked down to the lowest level after Jack killed him in the game's climax (if you make Jack choose to).
* A running theme in the ''Franchise/FireEmblem'' series is [[DragonsAreDivine dragons]] giving humans their blood in order to empower them, generally giving them the ability to use powerful "Holy Weapons." This always happens in the ancient backstories of each game, though, while the current heroes are descendants of the heroes given the dragon transfusion.

* There's a ''Webcomic/PennyArcade'' comic where, after a car-crash, Gabe and Tycho end up in the hospital and get blood-transfusions. Gabe ends up getting blood donated by Franchise/SpiderMan, and immediately develops web-shooting abilities, much to his joy. Tycho got [[ButtMonkey monkey-blood]].

* Creator/TexAvery plays it for laughs (natch) in the Creator/WalterLantz cartoon "WesternAnimation/CrazyMixedUpPup". A man and his dog are run over and the paramedics give them transfusions, only the man gets canine plasma and the dog gets human plasma, resulting in [[DelusionsOfDoghood a man acting like a dog and vice versa]].
* In ''WesternAnimation/YoungJustice'', Beast Boy's {{Animorphism}} (and green skin), instead of coming from SuperSerum as in the comics, was a side-effect of a life-saving blood transfusion from Miss Martian.

** In the episode "[[Recap/CharmedS2E20AstralMonkey Astral Monkey]]", a doctor is experimenting with the Charmed Ones' blood (long story, but he believes it could be the key to a "universal antibody") and unintentionally gives himself and his test subjects (three monkeys) their collective powers (he injected the monkeys with a mix of their blood, and they injected him). Unfortunately, mortals can't properly handle that kind of power, and it starts warping his body and mind; he "does good and saves innocents" by killing criminals and harvesting their organs for those that need them.

* In an episode ''Series/{{Charmed|1998}}'', a doctor is experimenting with the Charmed Ones' blood (long story, but he believes it could be the key to a "universal antibody") and unintentionally gives himself and his test subjects (three monkeys) their collective powers (he injected the monkeys with a mix of their blood, and they injected him). Unfortunately, mortals can't properly handle that kind of power, and it starts warping his body and mind; he "does good and saves innocents" by killing criminals and harvesting their organs for those that need them.

* Creator/TexAvery plays it for laughs (natch) in the Creator/WalterLantz cartoon "Crazy Mixed-up Pup". A man and his dog are run over and the paramedics give them transfusions, only the man gets canine plasma and the dog gets human plasma, resulting in a man acting like a dog and vice versa.