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See InhibitionDestroyingPuppet, [[ForumSpeak GIFT]], InVinoVeritas, DyingDeclarationOfLove, and DyingDeclarationOfHate for specific circumstances that can cause someone to lose their inhibitions. See TheSociopath to look at characters who ''start'' with no inhibitions rather than losing them.

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See InhibitionDestroyingPuppet, [[ForumSpeak GIFT]], InVinoVeritas, ButLiquorIsQuicker, DyingDeclarationOfLove, and DyingDeclarationOfHate for specific circumstances that can cause someone to lose their inhibitions. See TheSociopath to look at characters who ''start'' with no inhibitions rather than losing them.

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* ''VideoGame/NiNoKuni'': Shadar is capable of taking pieces of a person's heart containing one of their 8 virtues, including restraint. Queen Lowlah and Swaine, after losing their restraint, respectively become a glutton for cheese and a kleptomaniac who steals for no reason, forcing Oliver to find someone with a good amount of restraint to magically transfer to them.

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* ''VideoGame/NiNoKuni'': ''VideoGame/NiNoKuni'':
**
Shadar is capable of taking pieces of a person's heart containing one of their 8 virtues, including restraint. Queen Lowlah and Swaine, after losing their restraint, respectively become a glutton for cheese and a kleptomaniac who steals for no reason, forcing Oliver to find someone with a good amount of restraint to magically transfer to them.
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* Phineas Gage, a New England railroad worker, became disinhibited as the result of the 1848 accident that sent an iron rod through his head, destroying much of his frontal lobe. He started using profanity after almost never having done so before and developed a violent temper.

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* Phineas Gage, a New England railroad worker, became disinhibited as the result subject of the a lot of hype among neuroscientists following an 1848 accident that sent an iron rod through his head, destroying much of his frontal lobe. He started using [[MadeOfIron Amazingly, he survived (he never even lost consciousness or motor functions)]], and aside from becoming blind in one eye made an outstanding physical recovery, but it was widely reported that he experienced a major personality shift, starting to use profanity after almost never having done so before and developed developing a violent temper.temper. This led to a lot of discourse among psychologists discussing the function of the frontal lobe and results of compromising it, though [[UrbanLegends the validity of these claims have become increasingly debated]] due to some of the claims being highly contradictory (some claim he became a chronic womanizer and sexual deviant, others say he lost all interest in sex), as well as there being little to no documented sources backing them up, making Gage more of a case of folklore than actual scientific revelation.
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* In ''Literature/TheNameOfTheWind'', Kvothe is dosed with an alchemical poison called a "plum bob", which suppresses all inhibitions and appears to block the ability to make moral judgements.

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* The second StoryArc of ''LightNovel/KokoroConnect'', ''Kizu Random'', revolves around this, with [[BigBad Heartseed]] suppressing the inhibitions of the Student Cultural Society at random times. This causes the group to unleash their desires and commit such actions as Yui using excessive force on a group of guys sexually harassing girls, Aoki fighting off police officers arresting Yui, Inaba attempting to seduce Taichi, etc. This being a DeconstructorFleet, we get to see the terrifying results of losing your inhibitions and acting on your desires, especially if those desires are wrong.



* The second StoryArc of ''Literature/KokoroConnect'', ''Kizu Random'', revolves around this, with [[BigBad Heartseed]] suppressing the inhibitions of the Student Cultural Society at random times. This causes the group to unleash their desires and commit such actions as Yui using excessive force on a group of guys sexually harassing girls, Aoki fighting off police officers arresting Yui, Inaba attempting to seduce Taichi, etc. This being a DeconstructorFleet, we get to see the terrifying results of losing your inhibitions and acting on your desires, especially if those desires are wrong.
* ''[[Literature/TheStainlessSteelRat The Stainless Steel Rat Saves the World]]'': Jim had confidence issues before he had to accept a mission that the fate of the world hinges upon, so he takes a drug that suppresses a person's morals, giving him absolute confidence and self-righteousness. According to him, the drug is universally banned, but people who did take it were known to take over entire planets.



* ''[[Literature/TheStainlessSteelRat The Stainless Steel Rat Saves the World]]'': Jim had confidence issues before he had to accept a mission that the fate of the world hinges upon, so he takes a drug that suppresses a person's morals, giving him absolute confidence and self-righteousness. According to him, the drug is universally banned, but people who did take it were known to take over entire planets.
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** This then [[RecycledPlot gets repeated]] in the ''Series/StarTrekTheNextGeneration'' episode "The Naked Now".

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** This then [[RecycledPlot [[RecycledScript gets repeated]] in the ''Series/StarTrekTheNextGeneration'' episode "The "[[Recap/StarTrekTheNextGenerationS1E2TheNakedNow The Naked Now".Now]]".



* ''Series/TheSandman2022'', "[[Recap/TheSandman2022S01E05247 24/7]]": John Dee was raised by a mother who was a thief and a CompulsiveLiar, so he had developed a knee-jerk hatred of liars and dishonesty. When he retrieves Dream's Ruby, an AncientArtifact capable of controlling dreams, he intends on using it to change the world into a "more honest one". This translates to him taking away people's inhibitions, starting with people being more open about their feeling to one another, then having sex with each other before eventually devolving into them massacring one another. Dream explains that this is because he took away their dreams, and thus their reason to live.

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* ''Series/TheSandman2022'', ''Series/TheSandman2022'': In "[[Recap/TheSandman2022S01E05247 24/7]]": 24/7]]", John Dee was raised by a mother who was a thief and a CompulsiveLiar, so he had developed a knee-jerk hatred of liars and dishonesty. When he retrieves Dream's Ruby, an AncientArtifact capable of controlling dreams, he intends on using it to change the world into a "more honest one". This translates to him taking away people's inhibitions, starting with people being more open about their feeling to one another, then having sex with each other before eventually devolving into them massacring one another. Dream explains that this is because he took away their dreams, and thus their reason to live.
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* ''Literature/GroundedForAllEternity'': Parris initially influences the town by removing peoples' inhibitions and causing them to act on impulse.
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* ''Series/TheOuterLimits1995'' episode "From Within". Parasitic worms infest the inhabitants of a town and take over their brains. This causes the townsfolk to lose all of their inhibitions and start indulging in their deepest desires, including lots of sex and violence.

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* ''Series/TheOuterLimits1995'' ''Series/TheOuterLimits1995'': In the episode "From Within". Parasitic "[[Recap/TheOuterLimits1995S2E13FromWithin From Within]]", parasitic worms infest the inhabitants of a town and take over their brains. This causes the townsfolk to lose all of their inhibitions and start indulging in their deepest desires, including lots of sex and violence.
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In RealLife, this is called disinhibition, and it can be caused by drugs, [[InVinoVeritas alcohol]], or damage to the brain involving the Orbitofrontal cortex. It can also be the result of immaturity, repeated trauma, or mental illnesses.

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In RealLife, this is called disinhibition, and it can be caused by drugs, [[InVinoVeritas alcohol]], alcohol, or damage to the brain involving the Orbitofrontal cortex. It can also be the result of immaturity, repeated trauma, or mental illnesses.
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In RealLife, this is called disinhibition, and it can be caused by drugs, alcohol, or damage to the brain involving the Orbitofrontal cortex. It can also be the result of immaturity, repeated trauma, or mental illnesses.

to:

In RealLife, this is called disinhibition, and it can be caused by drugs, alcohol, [[InVinoVeritas alcohol]], or damage to the brain involving the Orbitofrontal cortex. It can also be the result of immaturity, repeated trauma, or mental illnesses.
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* The ''{{ComicBook/Crossed}}'' virus removes any and all inhibitions from its victims regardless of age, creating a HatePlague of rapist torturing murderers marked by a cross-shaped rash on the face. One utterly sociopathic SerialKiller didn't even notice he'd caught it at first, only looking into a mirror when he was curious as to why his neighbors were torturing their baby to death. Once he realized most of the world now thought the same way he did, he set out to let the Crossed pass for human to infiltrate society.

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* Invoked in the ''WesternAnimation/OzzyAndDrix'' episode "The Globfather". When Sal Monella and his gang enter Hector's stomach as a result of the latter eating a tainted corn dog and plan to inflict food poisoning after tricking the police force into going to the feet, Ozzy and Drix come up with a plan to turn Hector's fear off so he can go bungee jumping and vomit out the gang and the toxic waste they'll pour into Hector's stomach.

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* ''WesternAnimation/OzzyAndDrix''
**
Invoked in the ''WesternAnimation/OzzyAndDrix'' episode "The Globfather". When Sal Monella and his gang enter Hector's stomach as a result of the latter eating a tainted corn dog and plan to inflict food poisoning after tricking the police force into going to the feet, Ozzy and Drix come up with a plan to turn Hector's fear off so he can go bungee jumping and vomit out the gang and the toxic waste they'll pour into Hector's stomach.
** Attempted again in "Out of Body Experience", when they need Hector to go back in the pool with Christine so Ozzy (who got stuck in Christine's body) can swim home, but Hector's near-drowing experience left him afraid of swimming. They ultimately fail, but Hector's crush on Christine overrides his fear anyway.
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* ''Series/TheSandman2022'', "[[Recap/TheSandman2022S01E05247 24/7]]: John Dee was raised by a mother who was a thief and a CompulsiveLiar, so he had developed a knee-jerk hatred of liars and dishonesty. When he retrieves Dream's Ruby, an AncientArtifact capable of controlling dreams, he intends on using it to change the world into a "more honest one". This translates to him taking away people's inhibitions, starting with people being more open about their feeling to one another, then having sex with each other before eventually devolving into them massacring one another. Dream explains that this is because he took away their dreams, and thus their reason to live.

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* ''Series/TheSandman2022'', "[[Recap/TheSandman2022S01E05247 24/7]]: 24/7]]": John Dee was raised by a mother who was a thief and a CompulsiveLiar, so he had developed a knee-jerk hatred of liars and dishonesty. When he retrieves Dream's Ruby, an AncientArtifact capable of controlling dreams, he intends on using it to change the world into a "more honest one". This translates to him taking away people's inhibitions, starting with people being more open about their feeling to one another, then having sex with each other before eventually devolving into them massacring one another. Dream explains that this is because he took away their dreams, and thus their reason to live.
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* John Dee in ''Series/TheSandman2022'' was raised by a mother who was a thief and a CompulsiveLiar, so he had developed a knee-jerk hatred of liars and dishonesty. When he retrieves Dream's Ruby, an AncientArtifact capable of controlling dreams, he intends on using it to change the world into a "more honest one". This translates to him taking away people's inhibitions, starting with people being more open about their feeling to one another, then having sex with each other before eventually devolving into them massacring one another. Dream explains that this is because he took away their dreams, and thus their reason to live.

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* ''Series/TheSandman2022'', "[[Recap/TheSandman2022S01E05247 24/7]]: John Dee in ''Series/TheSandman2022'' was raised by a mother who was a thief and a CompulsiveLiar, so he had developed a knee-jerk hatred of liars and dishonesty. When he retrieves Dream's Ruby, an AncientArtifact capable of controlling dreams, he intends on using it to change the world into a "more honest one". This translates to him taking away people's inhibitions, starting with people being more open about their feeling to one another, then having sex with each other before eventually devolving into them massacring one another. Dream explains that this is because he took away their dreams, and thus their reason to live.
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--> '''John:''' They're lying to themselves. All lies.
--> '''Dream:''' Not lies, John. Dreams. Kate dreams of running away, where no one will find her. Garry dreams of proving his father was wrong about him. Bette dreams of creating something that matters to people. Their dreams inspired them. Their dreams kept them alive. But if you rob them of their dreams, if you take away their hope, then... yes, [[StrawNihilist this is the truth of mankind]].

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--> '''John:''' They're lying to themselves. All lies. \n--> \\
'''Dream:''' Not lies, John. Dreams. Kate dreams of running away, where no one will find her. Garry dreams of proving his father was wrong about him. Bette dreams of creating something that matters to people. Their dreams inspired them. Their dreams kept them alive. But if you rob them of their dreams, if you take away their hope, then... yes, [[StrawNihilist this is the truth of mankind]].
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Inhibition is the feeling of restraint. It imparts a subconscious limitation to act on our desires, especially if we know that what we're doing is wrong. So what happens if we lose those inhibitions? We indulge in our desires, acting upon them without compunction. Since these inhibitions keeping us grounded are usually ethical ones, this qualifies as [[AntagonistAbilities an innately villainous ability]]. If a normally good person were to be freed of their unwillingness to act upon their basic desires, [[DrivenToVillainy they could be capable of anything]]. They could give into their {{Greed}} and steal, lie to save their {{Pride}}, cheat for victory, give into their {{Lust}} and take a mistress, give into anger and [[WouldHurtAChild hit their child]], drink themselves sick, even commit murder.

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Inhibition is the feeling of restraint. It imparts a subconscious limitation to act on our desires, especially if we know that what we're doing is wrong. So what happens if we lose those inhibitions? We indulge in our desires, acting upon them without compunction. Since these inhibitions keeping us grounded are usually ethical ones, this qualifies as [[AntagonistAbilities an innately villainous ability]]. If a normally good person were to be freed of their unwillingness to act upon their basic desires, [[DrivenToVillainy they could be capable of anything]]. They could give into their {{Greed}} and steal, lie to save their {{Pride}}, cheat for victory, give into their {{Lust}} and take a mistress, give into anger and [[WouldHurtAChild hit their child]], drink themselves sick, even commit murder.



Several things can cause this to happen. Perhaps a PsychoSerum was administered to the unwilling victim, or maybe a god, devil, or other supernatural creature used their powers of temptation on them. [[FisherKingdom It could be something in the air]]. Who knows? This naturally can lead to MoreThanMindControl if that was the purpose behind it. The victim may even JumpOffTheSlipperySlope or become DrunkOnTheDarkSide.

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Several things can cause this to happen. Perhaps a PsychoSerum was administered to the unwilling victim, or maybe a god, devil, or other supernatural creature used their powers of temptation on them. [[FisherKingdom It could be something in the air]]. Who knows? This naturally can lead to MoreThanMindControl if that was the purpose behind it. The victim may even JumpOffTheSlipperySlope or become DrunkOnTheDarkSide. \n Since these inhibitions keeping us grounded are usually ethical ones, this qualifies as [[AntagonistAbilities an innately villainous ability]].
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Several things can cause this to happen. Perhaps a PsychoSerum was administered to the unwilling victim, or maybe a god, devil, or other supernatural creature used their powers of temptation on them. [[FisherKindgom It could be something in the air]]. Who knows? This naturally can lead to MoreThanMindControl if that was the purpose behind it. The victim may even JumpOffTheSlipperySlope or become DrunkOnTheDarkSide.

to:

Several things can cause this to happen. Perhaps a PsychoSerum was administered to the unwilling victim, or maybe a god, devil, or other supernatural creature used their powers of temptation on them. [[FisherKindgom [[FisherKingdom It could be something in the air]]. Who knows? This naturally can lead to MoreThanMindControl if that was the purpose behind it. The victim may even JumpOffTheSlipperySlope or become DrunkOnTheDarkSide.

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