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* ''Film/HellboyIITheGoldenArmy'': Abe Sapien tells a character that he has a nice baby only to be told "I'm not a baby, I'm a tumor" by the "baby".

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* ''Film/HellboyIITheGoldenArmy'': Abe Sapien One of the trolls at the Troll Market has something that looks like the upper body of a baby growing out of his chest. When Johann Krauss tells a character him that he has a nice baby only to be told baby, the "baby" replies "I'm not a baby, I'm a tumor" by the "baby". tumor."
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* ''WesternAnimation/TheFairlyOddParents'': Bob the Boil is a large boil on Elmer's face. Bob is sentient and can talk. His biggest wish is to take over the world. He has control over Elmer, which he also considers his best friend.

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* ''WesternAnimation/TheFairlyOddParents'': Bob the Boil is a large boil on Elmer's face. Bob face who is sentient and can talk. His biggest wish is to take over the world. He also has control over Elmer, which who he also considers his best friend.
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* ''TabletopGame/DungeonsAndDragons'': One of the Cancer Mage PrestigeClass's {{Lovecraftian Superpower}}s is an intelligent tumor, which grants them [[BizarreAlienSenses extra senses]], CombatClairvoyance, and CombatTentacles, and eventually learns its own spellcasting.
* ''TabletopGame/{{Pathfinder}}'': The {{Alchem|yIsMagic}}ist CharacterClass has the optional ability to grow a tumor on its body, which functions as a {{Familiar}} and can be temporarily detached to act autonomously.

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* ''TabletopGame/DungeonsAndDragons'': One of the Cancer Mage PrestigeClass's {{Lovecraftian Superpower}}s is an intelligent tumor, which tumor. It grants them [[BizarreAlienSenses extra senses]], CombatClairvoyance, and CombatTentacles, and eventually learns its own spellcasting.
* ''TabletopGame/{{Pathfinder}}'': The {{Alchem|yIsMagic}}ist CharacterClass has the optional ability to grow a tumor on its body, which body. It functions as a {{Familiar}} and can be temporarily detached detach to act autonomously.autonomously for a short time.
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* The ''WesternAnimation/OhYeahCartoons'' short "Fuzzy Bunny Presents: A Kid's Life" has Suzy Cornhusk tormented by sentient blackheads appearing on her nose, who even torment her with a VillainSong called "We Are the Stinkin' Blackheads".
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* ''WesternAnimation/TheAmazingWorldOfGumball'': In "The Game", Nicole gets a Dooj card that reads "You will doubt every thought you have." She gets a growth with her face on the side of her head that contradicts everything she says.
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* The ''Series/SaturdayNightLive'' sketch "Meatballs" has Sarah Sherman as a woman with semi-sentient "meatball" growths on her body that sing, dance, eat cheese, and vomit poisonous black goo.
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* ''WesternAnimation/TheGrimAdventuresOfBillyAndMandy'': In "Billy's Growth Spurt", Billy gets a sentient growth he calls "Yop-Yop" (from [[PokemonSpeak the sound it makes]]) as a side effect of one of Grim's family cures for indigestion. Yop-Yop starts growing as Billy feeds it junk food, and it eventually turns into a homonculous-like miniature Billy and jumps off Billy's back. Mandy gets rid of it by tricking it into drinking another of Grim's home remedies, causing it to dissolve into pink goo.

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* ''WesternAnimation/TheGrimAdventuresOfBillyAndMandy'': In "Billy's Growth Spurt", Billy gets a sentient growth he calls "Yop-Yop" (from [[PokemonSpeak the sound it makes]]) as a side effect of one of Grim's family cures for indigestion. Yop-Yop starts growing as Billy feeds it junk food, and it eventually turns into [[OurHomunculiAreDifferent a homonculous-like miniature Billy Billy]] and jumps off Billy's back. Mandy gets rid of it by tricking it into drinking another of Grim's home remedies, causing it to dissolve into pink goo.
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[[folder:Jokes]]
* A man goes to the doctor, removes his hat, and reveals there's a frog sitting on his head that seems fused to the scalp.
-->'''Doctor:''' Mary mother of God! How the hell did that happen!?\\
'''Frog:''' Well doc, a week ago it was just a boil on my ass!
[[/folder]]

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