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* Yukiji from ''Manga/KamisamaKiss'' hates youkai with a passion, going as far as to throw parties when she hears that one of them is being hunted down. [[spoiler: This becomes awkward when Tomoe, a LittleBitBeastly {{Kitsune}} starts to fall in love with her.]]

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* Yukiji from ''Manga/KamisamaKiss'' hates youkai with a passion, going as far as to throw parties when she hears that one of them is being hunted down. [[spoiler: This becomes awkward when Tomoe, a LittleBitBeastly {{Kitsune}} starts to fall in love with her.]]]]
* Most of ''Anime/TheUnlimitedHyoubuKyousuke'' revolves around normal humans' hatred of "espers" and vice versa. Many on both sides would like nothing more than to [[KillEmAll completely wipe out the other group]].

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*** [[spoiler: As such, they saw themselves as above the rest of the village and planned a Coup D'Tat despite being given more power than every other clan ''combined'' via being Military Police.]]

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*** [[spoiler: As such, they saw themselves as above the rest of the village and planned a Coup D'Tat coup d'etat despite being given more power than every other clan ''combined'' via being Military Police.]]]]
*** [[spoiler:Though the situation was a lot more complicated than that. The Uchiha ''themselves'' suffered discrimination at the hands of the Second Hokage, who not only considered them a cursed clan, but also likely held a grudge against them due to the death of his younger brother, who died during the shinobi clan wars. It was so bad that the Second ''deliberately'' made the entire system of the village against the Uchiha, and even ostracized them by putting their clan compound in the village outskirts, on the basis that they would eventually rebel either way. ''Orochimaru'' of all people called him out on it, pointing out that because of all that, the Second Hokage is probably the direct cause as to why the coup d'etat was about to happen in the first place. That's in comparison to his older brother, the First Hokage, who was completely impartial and was even ''best friends'' with an Uchiha]].
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*** [[spoiler: As such, they saw themselves as above the rest of the village and planned a Coup D'Tat despite being given more power than every other clan ''combined'' via being Military Police.]]
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* In TheLegendOfTheLegendaryHeroes, those born with [[EvilEye Cursed Eyes]] are heavily subject to this. Going by some characters' personal experiences and one character's recounts of what he's seen, children born with such eyes are generally persecuted, sold to/abducted by the military, used as test subjects, and killed, often alongside their parents--if their parents weren't the ones doing the killing. Conversely, a fair number of Cursed Eye bearers are prejudiced towards humans right back.

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* In TheLegendOfTheLegendaryHeroes, those born with [[EvilEye Cursed Eyes]] are heavily subject to this. Going by some characters' personal experiences and one character's recounts of what he's seen, children born with such eyes are generally persecuted, sold to/abducted by the military, used as test subjects, and killed, often alongside their parents--if their parents weren't the ones doing the killing. Conversely, a fair number of Cursed Eye bearers are prejudiced towards humans right back.back.
* Yukiji from ''Manga/KamisamaKiss'' hates youkai with a passion, going as far as to throw parties when she hears that one of them is being hunted down. [[spoiler: This becomes awkward when Tomoe, a LittleBitBeastly {{Kitsune}} starts to fall in love with her.]]
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* In a major case of AllThereInTheManual, it's revealed that the ''Anime/TenchiMuyo''-based alien race, Juraians, have a major thing against humans, most likely due to their "backwater" nature (seeing as humans still don't have FasterThanLight travel). This is one of the major reasons Yosho took off after Ryoko - he didn't want to deal with all of that and intended to send someone else in his place.

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* In a major case of AllThereInTheManual, it's revealed that the ''Anime/TenchiMuyo''-based alien race, Juraians, have a major thing against humans, most likely due to their "backwater" nature (seeing as humans still don't have FasterThanLight travel). This is one of the major reasons Yosho took off after Ryoko - he didn't want to deal with all of that and intended to send someone else in his place.place.
* In TheLegendOfTheLegendaryHeroes, those born with [[EvilEye Cursed Eyes]] are heavily subject to this. Going by some characters' personal experiences and one character's recounts of what he's seen, children born with such eyes are generally persecuted, sold to/abducted by the military, used as test subjects, and killed, often alongside their parents--if their parents weren't the ones doing the killing. Conversely, a fair number of Cursed Eye bearers are prejudiced towards humans right back.
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* Done in both the manga and anime versions of ''FullmetalAlchemist'', with the persecution and attempted genocide of the Ishvalan people. They are visually identifiable by their red eyes and dark skin, and various characters use hats and sunglasses to 'pass'. Several aspects of the Ishvalans' portrayal hint more specifically at a metaphorically Islamic culture: their vaguely Middle Eastern dress, Ishval's desert landscape, and their monotheistic religion and the tensions arising from its prohibition of alchemy and the Amestrians' contrasting dependence upon it.

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* Done in both [[Manga/FullmetalAlchemist the manga manga]] and anime [[Anime/FullmetalAlchemist the anime]] versions of ''FullmetalAlchemist'', ''Fullmetal Alchemist'', with the persecution and attempted genocide of the Ishvalan people. They are visually identifiable by their red eyes and dark skin, and various characters use hats and sunglasses to 'pass'.disguise these traits. Several aspects of the Ishvalans' portrayal hint more specifically at a metaphorically Islamic culture: their vaguely Middle Eastern dress, Ishval's desert landscape, and their monotheistic religion and the tensions arising from its prohibition of alchemy and the Amestrians' contrasting dependence upon it.
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** It really shows up in the Japanese version of the first movie, where Mew says that the clones should die and are inferior to the originals.
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* The people of the Ceres slums of ''LightNovel/AiNoKusabi'' are discriminated against for being born in an area cut off from society with no chance for a future. It is so bad that the [[LegoGenetics genetically engineered]] [[TheBeautifulElite class of Elites]] in their CrapsackWorld don't even consider them to be human but wild animals.

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* The people of the Ceres slums of ''LightNovel/AiNoKusabi'' are discriminated against for being born in an area cut off from society with no chance for a future. It is so bad that the [[LegoGenetics genetically engineered]] [[TheBeautifulElite class of Elites]] in their CrapsackWorld don't even consider them to be human but wild animals.animals.
* In a major case of AllThereInTheManual, it's revealed that the ''Anime/TenchiMuyo''-based alien race, Juraians, have a major thing against humans, most likely due to their "backwater" nature (seeing as humans still don't have FasterThanLight travel). This is one of the major reasons Yosho took off after Ryoko - he didn't want to deal with all of that and intended to send someone else in his place.
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* In ''ArmitageIII'', the title character is a RidiculouslyHumanRobot (in fact, she's so ridiculously human [[spoiler: she can even reproduce]], which is a plot point) working to investigate murders (of victims who turn out to be similar RidiculouslyHumanRobots) with a partner who's prejudiced against robots and cyborgs due to one causing the death of his previous partner. He is injured, and [[KarmicTransformation repaired with robotic prosthetics]]. Of course, he gets an {{Aesop}} about tolerance, and eventually [[spoiler: marries his mechanical partner]].

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* In ''ArmitageIII'', the title character is a RidiculouslyHumanRobot (in fact, she's so ridiculously human [[spoiler: she can even reproduce]], which is a plot point) working to investigate murders (of victims who turn out to be similar RidiculouslyHumanRobots) with a partner who's prejudiced against robots and cyborgs due to one causing the death of his previous partner. He is injured, and [[KarmicTransformation repaired with robotic prosthetics]]. Of course, he gets an {{Aesop}} about tolerance, and eventually [[spoiler: marries his mechanical partner]].partner and has even a baby with her]].
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* [[RealityWarper Rustyrose]] from ''FairyTail'' declares that all non-wizards are trash and deserve to die. When Elfman expresses disgust at this and says that wizards and regular people have to work together for the common good, Rustyrose calls him a fool and says that Elfman and his friends are trash as well.

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* [[RealityWarper Rustyrose]] from ''FairyTail'' ''Manga/FairyTail'' declares that all non-wizards are trash and deserve to die. When Elfman expresses disgust at this and says that wizards and regular people have to work together for the common good, Rustyrose calls him a fool and says that Elfman and his friends are trash as well.
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* ''SoulEater'' has a bit of this, although it is mentioned only in passing. However, it is directly stated in ''SoulEaterNot'' that ordinary humans fear Demon Weapons greatly, hence the law that anyone displaying those abilities must attend the DWMA until they are certified safe for society. Soul, the second protagonist, comes from an all-human family of musicians, and they were apparently "surprised" when the youngest family member turned out to be a living razor. Based on Soul's self-esteem issues related to his weapon blood, their unhappiness is inferred.

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* ''SoulEater'' has a bit of this, although it is mentioned only in passing. However, it is directly stated in ''SoulEaterNot'' that ordinary humans fear Demon Weapons greatly, hence the law that anyone displaying those abilities must attend the DWMA until they are certified safe for society. Soul, the second protagonist, comes from an all-human family of musicians, and they were apparently "surprised" when the youngest family member turned out to be a living razor. Based on Soul's self-esteem issues related to his weapon blood, their unhappiness disappointment is inferred.
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* ''SoulEater'' has a bit of this, although it is mentioned only in passing. However, it is directly stated in ''SoulEaterNot'' that ordinary humans feared weapons greatly, hence the law that anyone displaying those abilities must attend the DWMA until they are certified safe for society.

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* ''SoulEater'' has a bit of this, although it is mentioned only in passing. However, it is directly stated in ''SoulEaterNot'' that ordinary humans feared weapons fear Demon Weapons greatly, hence the law that anyone displaying those abilities must attend the DWMA until they are certified safe for society.society. Soul, the second protagonist, comes from an all-human family of musicians, and they were apparently "surprised" when the youngest family member turned out to be a living razor. Based on Soul's self-esteem issues related to his weapon blood, their unhappiness is inferred.
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* ''SoulEater'' has a bit of this, although it is mentioned only in passing. However, it is directly stated in ''SoulEaterNot''! that ordinary humans feared weapons greatly, hence the law that anyone displaying those abilities must attend the DWMA until they are certified safe for society.

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* ''SoulEater'' has a bit of this, although it is mentioned only in passing. However, it is directly stated in ''SoulEaterNot''! ''SoulEaterNot'' that ordinary humans feared weapons greatly, hence the law that anyone displaying those abilities must attend the DWMA until they are certified safe for society.
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* ''SoulEater'' has a bit of this, although it is mentioned only in passing. However, it is directly stated in ''SoulEaterNot''! that ordinary humans feared weapons greatly, hence the law that anyone displaying those abilities must attend the DWMA until they are certified safe for society.
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* ''OnePiece'' has a complicated example with the Fishmen and the Mermen, humanoid beings that also show characteristics of an aquatic animal. Since the "aquatic animal" part is almost random and they have a lot of possible combinations, neither the Fishmen nor the Mermen discriminate against each other by distinctive traits such as their fish parts. Because of this, is perfectly normal for them that an octopus Mermaid reproduce with a shark Merman and a eel Merman be born as the result, that's also why they can't understand why the Humans classify each other in groups. But even if those species don't discriminate amongst themselves, they do discriminate against other races. Specifically, the Fishmen believe that they're superior to all other races, especially Humans, but that's also complicated because of the discrimination that the Humans have in the One Piece world against them and the Mermen.
** To be fair, not all Fishmen and Mermaids believe that they're ''superior'' to humans or other races, only certain extremists, though the overwhelming majority does hate and distrust the human race.

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* ''OnePiece'' has a complicated example with the Fishmen and the Mermen, Merfolk, humanoid beings that also show characteristics of an aquatic animal. Since the "aquatic animal" part is almost random and they have a lot of possible combinations, neither the Fishmen nor the Mermen discriminate against each other by distinctive traits such as their fish parts. Because of this, is perfectly normal for them that an octopus Mermaid reproduce with a shark Merman and a eel Merman be born as the result, that's also why they can't understand why the Humans classify each other in groups. But even if those species don't discriminate amongst themselves, they do discriminate against other races. Specifically, the Fishmen believe that they're superior to all other races, especially Humans, but that's also complicated because of the discrimination that the Humans have in the One Piece world against them and the Mermen.
** To be fair, not all Fishmen and Mermaids Merfolk believe that they're ''superior'' to humans or other races, only certain extremists, though the overwhelming majority does hate and distrust the human race.



*** Taken to the extreme by Hody Jones, who is is so racist [[spoiler: that he's willing to have hundreds, if not thousands, of fishpeople and merpeople murdered for wishing to be on civil terms with humans. This includes the much-beloved Queen Otohime, for being the figurehead of the movement.]] The real kicker: he flat out admits that [[spoiler:humans have never done anything bad to him personally. He's simply internalized the Fishmen's prejudices against humans.]]

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*** Taken to the extreme by Hody Jones, who is is so racist [[spoiler: that he's willing to have hundreds, if not thousands, of fishpeople Fishmen and merpeople Merfolk murdered for wishing to be on civil terms with humans. This includes the much-beloved Queen Otohime, for being the figurehead of the movement.]] The real kicker: he flat out admits that [[spoiler:humans have never done anything bad to him personally. He's simply internalized the Fishmen's prejudices against humans.]]

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* ''{{Kikkaider}}'' had a discussed double example of this, combined with a fantastic version of HalfbreedDiscrimination. A villain, who is an android in the shape of a vampire or a golden, mechanical, humanoid vampire bat, says that being an android is similar to being a bat in this respect, claiming that androids were not quite machine or human, but disliked by both and that a bat was not quite rodent or bird, but also disliked by both (the jury is still a bit out on that last one).

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* ''{{Kikkaider}}'' ''{{Series/Kikaider}}'' had a discussed double example of this, combined with a fantastic version of HalfbreedDiscrimination. A villain, who is an android in the shape of a vampire or a golden, mechanical, humanoid vampire bat, says that being an android is similar to being a bat in this respect, claiming that androids were not quite machine or human, but disliked by both and that a bat was not quite rodent or bird, but also disliked by both (the jury is still a bit out on that last one).one).
* The people of the Ceres slums of ''LightNovel/AiNoKusabi'' are discriminated against for being born in an area cut off from society with no chance for a future. It is so bad that the [[LegoGenetics genetically engineered]] [[TheBeautifulElite class of Elites]] in their CrapsackWorld don't even consider them to be human but wild animals.
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* [[DigimonSavers Kurata]] fullstop. He hates Digimon to the point where he warps Digimon data so that it can [[spoiler: be used as a weapon to introduce genocide in a word that does not know death.]] Of course, this takes place before the series starts; in series, his racism just [[spoiler: causes more genocide, medically alters people, and sets off a chain of events that nearly causes the end of both worlds.]]

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* [[DigimonSavers [[Anime/DigimonSavers Kurata]] fullstop. He hates Digimon to the point where he warps Digimon data so that it can [[spoiler: be used as a weapon to introduce genocide in a word that does not know death.]] Of course, this takes place before the series starts; in series, his racism just [[spoiler: causes more genocide, medically alters people, and sets off a chain of events that nearly causes the end of both worlds.]]



* In ''DigimonFrontier'', before the start of the series there was a war between human and beast Digimon which Lucemon stops. In the movie there is an island where a civil war between the human and beast Digimon there, which was perpetrated by a Digimon who can slide digivolve from human and beast forms to awaken Ornismon.

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* In ''DigimonFrontier'', ''Anime/DigimonFrontier'', before the start of the series there was a war between human and beast Digimon which Lucemon stops. In the movie there is an island where a civil war between the human and beast Digimon there, which was perpetrated by a Digimon who can slide digivolve from human and beast forms to awaken Ornismon.

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*** Taken to the extreme by Hody Jones, who is is so racist [[spoiler: that he's willing to have hundreds, if not thousands, of fishpeople and merpeople murdered for wishing to be on civil terms with humans. This includes the much-beloved Queen Otohime, for being the figurehead of the movement.]]

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*** Taken to the extreme by Hody Jones, who is is so racist [[spoiler: that he's willing to have hundreds, if not thousands, of fishpeople and merpeople murdered for wishing to be on civil terms with humans. This includes the much-beloved Queen Otohime, for being the figurehead of the movement.]] The real kicker: he flat out admits that [[spoiler:humans have never done anything bad to him personally. He's simply internalized the Fishmen's prejudices against humans.]]
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* ''{{Akikan}}'' has aluminum and steel cans (the cans are [[MoeAnthropomorphism cute girls]] here) holding some deep prejudice against each other. The first time this comes to light is when Melon and Yell begin slinging insults at each other based solely on the material they're made out of. The fact that this type of [[ThereCanBeOnlyOne competition]] is encouraged doesn't help.

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* ''{{Akikan}}'' ''LightNovel/{{Akikan}}'' has aluminum and steel cans (the cans are [[MoeAnthropomorphism cute girls]] here) holding some deep prejudice against each other. The first time this comes to light is when Melon and Yell begin slinging insults at each other based solely on the material they're made out of. The fact that this type of [[ThereCanBeOnlyOne competition]] is encouraged doesn't help.
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**To be fair, not all Fishmen and Mermaids believe that they're ''superior'' to humans or other races, only certain extremists, though the overwhelming majority does hate and distrust the human race.
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* Witches in ''RosarioToVampire'' are hated both by humans and youkai, since they're considered [[HalfHumanHybrid half-breeds]], and [[TragicMulatto neither side trusts them.]] CuteWitch Yukari gets this treatment during her first appearance (manga ch. 5), although part of it comes from [[BrattyHalfPint her tendency to play magical pranks on others]].

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* Witches in ''RosarioToVampire'' are hated both by humans and youkai, since they're considered [[HalfHumanHybrid half-breeds]], and [[TragicMulatto [[HalfBreedDiscrimination neither side trusts them.]] CuteWitch Yukari gets this treatment during her first appearance (manga ch. 5), although part of it comes from [[BrattyHalfPint her tendency to play magical pranks on others]].



* ''{{Kikkaider}}'' had a discussed double example of this, combined with a fantastic version of TragicMulatto. A villain, who is an android in the shape of a vampire or a golden, mechanical, humanoid vampire bat, says that being an android is similar to being a bat in this respect, claiming that androids were not quite machine or human, but disliked by both and that a bat was not quite rodent or bird, but also disliked by both (the jury is still a bit out on that last one).

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* ''{{Kikkaider}}'' had a discussed double example of this, combined with a fantastic version of TragicMulatto.HalfbreedDiscrimination. A villain, who is an android in the shape of a vampire or a golden, mechanical, humanoid vampire bat, says that being an android is similar to being a bat in this respect, claiming that androids were not quite machine or human, but disliked by both and that a bat was not quite rodent or bird, but also disliked by both (the jury is still a bit out on that last one).
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* This trope is the core of the conflict between those with PsychicPowers known as the Mu and normal humans in ''Manga/TowardTheTerra''.

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* This trope is the core of the conflict between those with PsychicPowers known as the Mu and normal humans in ''Manga/TowardTheTerra''.''Manga/TowardTheTerra''.
* ''{{Kikkaider}}'' had a discussed double example of this, combined with a fantastic version of TragicMulatto. A villain, who is an android in the shape of a vampire or a golden, mechanical, humanoid vampire bat, says that being an android is similar to being a bat in this respect, claiming that androids were not quite machine or human, but disliked by both and that a bat was not quite rodent or bird, but also disliked by both (the jury is still a bit out on that last one).
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** A lot of monsters also seem to believe that {{humans are bastards}}.

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** A lot of monsters also seem to believe that {{humans are bastards}}.the real monsters}}.
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* Kind of the point in ''ElfenLied''. Although Diclonii ''are'' an actual threat to humanity as a species, from what we're shown it's humans who cause a lot of the threat, combined with the simple fact that children should not have weapons.

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* Kind of the point in ''ElfenLied''. Although Diclonii ''are'' an actual threat to humanity as a species, from what we're shown it's humans who cause a lot of the threat, combined with the simple fact that children should not have weapons.s
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* Friction exists between all of the races in ''{{Slayers}}'': the dragons and the ''Shinzoku'' (Holy race) that serve the Gods, the ''Mazoku'' ("evil race") that serve the Demons/Monsters, and [[OurElvesAreDifferent Elves]] all either scorn humans or manipulate them in some way or another (the first two are rather obvious, wile the Elves feel superior because they have a better innate talent with magic than many humans do). Meanwhile, most of the sub-human races (Beastmen, Berserkers, Fish-people) are either peaceful, subservient, or also scorned upon by the other three, as well as humans; the Fish-people in particular are often exploited for [[ButtMonkey comedy relief]]. The ones that gets the worst of it, however, are chimeras.
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* ''Superior'' has humans and monsters gleefully killing one another.

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* ''Superior'' ''Manga/{{Superior}}'' has humans and monsters gleefully killing one another.
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*** [[HumansAreTheRealMonsters Considering, what we do to eachother and to other, they're maybe right.]]
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** Uzumaki Clan was attacked and finally destroyed, because their sealing techniques were widely feared.

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** The village, where the Uzumaki Clan lived, was attacked and finally destroyed, because their sealing techniques were widely feared.
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* ''BlackButler'', intensified sixfold in the manga. Demons and Shinigami hate each other. In the Noah's Arc Circus part, William and Sebastian spend a few days and nights trash-talking each other not as individuals but as representatives of their respective races...Except for Grell, who will flirt with anything so long as it's male and sadistic.
** Both species also despise Angels in the anime, though their position is seemingly justified. It's never made clear whether [[PlanetofHats all angels are]] LawfulEvil or not, since [[AxCrazy only]] [[KnightTemplar one angel]] appears; it's entirely possible this was just [[FallenAngel a bad one]].
* In ''DarkerThanBlack'', a man in charge of a secret operation tells the [[DealWithTheDevil Contractor]] working under him, ''"Your whole kind is nothing more than filth, unfit to live without a patron's approval."'' That the man in charge is white and the Contractor black is incidental, though this possibly counts as a LampshadeHanging.
* Done in ''PetoPetoSan'', where Japanese mythological creatures are either humanoid or have [[HalfHumanHybrid mated with humans enough to do so]]. The problem is averted by the series taking a lighter tone, and the solution involves something everyone can get behind, dedicating the town to "Little Sister" {{Moe}}.
* ''MobileSuitGundam'' had conflicts between "Earthnoids" (humans who lived on Earth) and "Spacenoids" (humans who lived in space). Closely related was the conflict between Newtypes (those with PsychicPowers, almost always Spacenoids) and Oldtypes (non-psychics, but also used as a slur for those stuck in old ways of thinking).
** ''GundamSEED'' had Naturals ([[PunyEarthlings normal humans]]) versus Coordinators ([[BornWinner genetically engineered humans]]).
* {{Escaflowne}}'s Dragon Clan are hated by almost ''every'' other race on Gaea, it is so frowned upon that the [[HalfHumanHybrid main character's]] Mother, makes him promise ''never'' to show his wings again, just seeing the wings of one is said to be a bad omen.
** However the last part is subverted [[spoiler: when Van's unfurled wings manages to bring the rest of the world, drunk on the power of wishing, back to its senses.]]
* InuYasha has half-demons, which are hated by both humans and demons, with humans and demons also hating each other.
** Though the humans hating demons aspect is generally deserved, since upwards of 90% of all pure-blooded demons are either out to kill humans on principle, or target humans for pranks or worse without consideration for the victim. Which is not to say that humans NEVER act in such a manner, just that there are some positive examples also.
* ''{{Naruto}}'': In an early arc, Haku explained that in the Land of Water the powerful and deadly abilities of clans with bloodline abilities had garnered fear and hatred from those without such abilities. The hatred was so severe that Haku's father was willing to murder his wife and son because of their bloodline.
** The Uchiha in general believed themselves superior to other shinobi simply because they were Uchiha, often reflected in Sasuke's arrogance.
** And there's also the jinchuriki, who are feared, hated, and ostracized by their home villages, or exploited and used as weapons by other people. This is a recurring theme in ''Shippuden'', where Naruto repeatedly calls out people that insult jinchuriki.
*** And that can include even saying the word, "jinchuriki." [[NWordPrivileges Unless you know him or have a tailed beast yourself, do not call Naruto a Jinchuriki.]] The word was created to dehumanize the people containing the beasts in the minds of their creators.
** Uzumaki Clan was attacked and finally destroyed, because their sealing techniques were widely feared.
* In the ''Anime/BloodPlus'' episode "Turn the Palm of Your Hand Toward the Sun", James Ironside delivers a crazed rant about the Schiffs' inferiority to Chevaliers such as himself - while trying to torture a captured Schiff to death. The scene is even more chilling because James, who is black, seems to have no idea of the terrible irony of his words and actions.
** And also because [[spoiler: his arms and the lower part of his body, which were destroyed and replaced with body parts from the Schiff, are now white. Being rejected by his capricious "mother" because of the replaced body parts is precisely what drove James (who is a fairly straightforward [[TheRenfield Renfield]]) insane, to boot]]. Even if this wasn't intended to be part of the irony, it was certainly unsettling.
* A major theme of ''TrinityBlood'' is that vampires and humans can and should stop fighting and live in harmony.
* In ''ArmitageIII'', the title character is a RidiculouslyHumanRobot (in fact, she's so ridiculously human [[spoiler: she can even reproduce]], which is a plot point) working to investigate murders (of victims who turn out to be similar RidiculouslyHumanRobots) with a partner who's prejudiced against robots and cyborgs due to one causing the death of his previous partner. He is injured, and [[KarmicTransformation repaired with robotic prosthetics]]. Of course, he gets an {{Aesop}} about tolerance, and eventually [[spoiler: marries his mechanical partner]].
* In ''BubblegumCrisis'', there's prejudice against Boomers. Whether or not this influences them to go rogue varies.
* Done in both the manga and anime versions of ''FullmetalAlchemist'', with the persecution and attempted genocide of the Ishvalan people. They are visually identifiable by their red eyes and dark skin, and various characters use hats and sunglasses to 'pass'. Several aspects of the Ishvalans' portrayal hint more specifically at a metaphorically Islamic culture: their vaguely Middle Eastern dress, Ishval's desert landscape, and their monotheistic religion and the tensions arising from its prohibition of alchemy and the Amestrians' contrasting dependence upon it.
** There's also the Ishvalan prejudice or prosecution of alchemists. This is somewhat more understandable, since the alchemists were responsible for the aforementioned genocide in the first place.
* Probably the first & still one of the best examples in anime is OsamuTezuka's ''Anime/{{Astroboy}}''. Some choice examples: the robot revolutionary Blue Knight explicitly compares the robot nation he is trying to build to Israel, "The Tragedy of Bailey" storyline, where a Japanese-American cyborg brings Astro to America to try to protect the first robot to gain US citizenship from being lynched & the "Capetown Lulaby" story, which [[RippedFromTheHeadlines was inspired by issues of the time such as Apartheid & segregation]] & the latter half even takes place in South Africa. What's really strange is that the badguys from that story disguise themselves by putting on blackface.
* Kind of the point in ''ElfenLied''. Although Diclonii ''are'' an actual threat to humanity as a species, from what we're shown it's humans who cause a lot of the threat, combined with the simple fact that children should not have weapons.
* The battle of [=ESPers=] vs. "Normal People" in ''ZettaiKarenChildren'' is one of the underlying themes of the series. Almost all of the [=ESPers=] in the series are under the watch of the government, and it's shown that when someone is discovered to have powers, they're treated harshly for it. Good thing Minamoto serves as MoralityChain to The Children.
* Witches in ''RosarioToVampire'' are hated both by humans and youkai, since they're considered [[HalfHumanHybrid half-breeds]], and [[TragicMulatto neither side trusts them.]] CuteWitch Yukari gets this treatment during her first appearance (manga ch. 5), although part of it comes from [[BrattyHalfPint her tendency to play magical pranks on others]].
** A lot of monsters also seem to believe that {{humans are bastards}}.
* ''{{Akikan}}'' has aluminum and steel cans (the cans are [[MoeAnthropomorphism cute girls]] here) holding some deep prejudice against each other. The first time this comes to light is when Melon and Yell begin slinging insults at each other based solely on the material they're made out of. The fact that this type of [[ThereCanBeOnlyOne competition]] is encouraged doesn't help.
* ''{{Anime/Pokemon}}'' has done episodes that evoke this. One example from the Kanto episodes is "Bulbasaur and the Mysterious Garden", where Ash's Bulbasaur's refusal to evolve causes the newly evolved Ivysaur and their chief, a Venusaur, to turn on him. Another episode during Johto featured a group of Remoraid (a fish-like Pokémon) that shunned one of their clan after it evolved into an Octillery (an octopus Pokémon). Mewtwo and his army of clone Pokémon (both versions) and Mew and his army of natural born Pokemon (Japanese version only, at least in regards to Mew itself) is also an example of this.
** It really shows up in the Japanese version of the first movie, where Mew says that the clones should die and are inferior to the originals.
* ''OnePiece'' has a complicated example with the Fishmen and the Mermen, humanoid beings that also show characteristics of an aquatic animal. Since the "aquatic animal" part is almost random and they have a lot of possible combinations, neither the Fishmen nor the Mermen discriminate against each other by distinctive traits such as their fish parts. Because of this, is perfectly normal for them that an octopus Mermaid reproduce with a shark Merman and a eel Merman be born as the result, that's also why they can't understand why the Humans classify each other in groups. But even if those species don't discriminate amongst themselves, they do discriminate against other races. Specifically, the Fishmen believe that they're superior to all other races, especially Humans, but that's also complicated because of the discrimination that the Humans have in the One Piece world against them and the Mermen.
** The giants also get treated on the same level as a tank. They don't really like that. That's only really by the marines though, some are highly respected people and are treated as honorable guests.
** There's also the Long-arm tribe looking for "rare people with only one joint in their arms" to put on display, or the occasional flickers of fantastic racism towards Brook (for looking like a monster) and more subtly Franky (looks like a monster without his fake skin). Basically you can be any skin color you want and no one will mind, but if you don't look human enough for the OP world's tastes things are gonna be rough.
*** Taken to the extreme by Hody Jones, who is is so racist [[spoiler: that he's willing to have hundreds, if not thousands, of fishpeople and merpeople murdered for wishing to be on civil terms with humans. This includes the much-beloved Queen Otohime, for being the figurehead of the movement.]]
* Fate has shown some evidence of this in ''MahouSenseiNegima''. Some of his internal monologues seem to indicate he doesn't consider the people of the Magic World to be ''real''. Except for the human population of Megalosembria, they ''are'' artificial beings who will fade from existence when (''when'', not if) the Mundus Magicus collapses. And far from persecuting them for it, he actually claims he's trying to ''save'' them, in his own twisted way.
* In the ''AngelSanctuary'' manga, angels are created ''in vitro''. Naturally-bred angels are looked down upon, and outright hunted whenever they can find an excuse (the [[LaResistance rebellion]] helps on that). They are often born with pale skin and red eyes, which gives them the slur name of "rabbits". This often borders on BullyingADragon, since rabbits are often born with extreme and uncontrolled powers.
* The Saiyans of ''Manga/DragonBall Z'' were undoubtedly subjected to racism by Freeza and his men, leading up to Freeza single-handedly carrying out a genocide against them by destroying their planet. As we see in some episodes, the remaining Saiyans had to deal with discrimination, and being called [[FantasticSlurs 'filthy monkeys']].
** Subverted somewhat in that Freeza's real motivation was fear, the racism was mostly a cover. He destroyed their planet because he feared a Saiyan uprising, not because he particularly hated them.
** Freeza's racism is played up even more in [[DragonballAbridged the abridged series]]. He despises most races he encounters, but claims he's not actually a racist since he just wipes them out rather than hating them.
* There's the double whammy in ''{{Niea_7}}'', where the aliens not only face discrimination by earthlings, but also maintain a kind of [[FantasticCasteSystem caste system]] for ''each other'', in which lower-ranked aliens like Niea are regarded as worthless scum.
* ''OjamajoDoremi'': A bunch of grey elephants don't want to play with a white elephant because he's white. DoesThisRemindYouOfAnything?
* The Plants in {{Trigun}} are conscious beings that humans exploit for power, resources, etc. Though to be fair, most humans don't know that the Plants are even alive, let alone sentient.
* In TengenToppaGurrenLagann, [[spoiler: the Anti-Spiral hates and deplores other Spiral Races, partly because of the Spiral Nemesis, but this doesn't prevent him from going on tangents that, quite frankly, wouldn't be very justified, even with the Spiral Nemesis as his excuse]].
* [[DigimonSavers Kurata]] fullstop. He hates Digimon to the point where he warps Digimon data so that it can [[spoiler: be used as a weapon to introduce genocide in a word that does not know death.]] Of course, this takes place before the series starts; in series, his racism just [[spoiler: causes more genocide, medically alters people, and sets off a chain of events that nearly causes the end of both worlds.]]
* Togusa of ''GhostInTheShellStandAloneComplex'' has some technophobia as part of his old fashioned/FanOfThePast personality. He is initially somewhat hostile to the Tatchikomas because he bristles at the idea of their being a fully sapient artificial intelligence. In the second season, he gets set up and put through a show trial after he shoots a cyborg criminal while off duty. The main thrust of the prosecution's argument is that Togusa is prejudiced against cyborgs due to subconscious feelings of inferiority.
* ''Superior'' has humans and monsters gleefully killing one another.
* In ''EveNoJikan'', robots are portrayed as harmless and, in some cases, [[{{Ridiculously Human Robots}} genuinely good-willed]], not to mention {{three laws compliant}}, but the [[{{Well Intentioned Extremist}} Ethics Committee]] is flat-out against robots integrating into human life, especially if--[[{{Sarcasm Mode}} God forbid]]--they begin developing personalities.
* In ''TigerAndBunny'', it's noted that there used to be a tremendous amount of anti-[[DifferentlyPoweredIndividual NEXT]] sentiment, though it has lessened considerably in the past twenty years (due to the emergence of [[spoiler:Maverick's]] superheroes). History of NEXT-prejudice nonetheless has an impact on the characters (both Kotetsu and [[spoiler:Kriem]] grew up during this time period, and thus had to endure a lot of stigma) and on the plot ([[spoiler:[=HeroTV=] was floundering because of it, so Maverick set up a MonsterProtectionRacket to keep it alive]]).
* In ''DigimonFrontier'', before the start of the series there was a war between human and beast Digimon which Lucemon stops. In the movie there is an island where a civil war between the human and beast Digimon there, which was perpetrated by a Digimon who can slide digivolve from human and beast forms to awaken Ornismon.
* An episode of ''Manga/KimbaTheWhiteLion'' has Kimba go to a lion convention only to be called a "pussy cat" for being white by the meeting's leader Specklerex and other lions. It turns out that Specklerex was jealous towards Kimba's father Ceaser [[AlwaysSomeoneBetter for being a more successful leader than him]] and by the end of the episode, Specklerex developed some respect towards Kimba.
* In ''KidouShinsengumiMoeyoKen'', two minor characters, a CatGirl and a regular human man, are seen from time to time in a love/hate relationship, and then they finally decide to marry, but the man's mother adamantly refuses to allow the CatGirl to marry him. This serves as a plot point later when Okita asks Ryunosuke's mother, Oryo, if she was okay with a half-monster daughter marrying her son. Oryo's reaction is one of shock shortly after Okita asks it, and she walks away dejectedly. [[spoiler: Unfortunately for her, Oryo wasn't shocked at her question, but rather some cockroaches which were on the wall behind Okita, and apparently didn't hear her question. Later on we find out Oryo's perfectly okay with Okita marrying Ryunosuke if she wanted to marry him.]]
* [[RealityWarper Rustyrose]] from ''FairyTail'' declares that all non-wizards are trash and deserve to die. When Elfman expresses disgust at this and says that wizards and regular people have to work together for the common good, Rustyrose calls him a fool and says that Elfman and his friends are trash as well.
* Momose, a pure blooded cat demon from ''Manga/BloodyCross'' refers to [[HalfHumanHybrids half breeds]] as "vulgar, barbaric and the lowest of the low".
* In ''SaintBeast'', Kira and Maya face discrimination for being [[HalfHumanHybrid half-human, half-angels]].
* This trope is the core of the conflict between those with PsychicPowers known as the Mu and normal humans in ''Manga/TowardTheTerra''.

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