History DelicateAndSickly / LiveActionTV

** Alicia, a cute young girl in a wheelchair from ''Series/MariaLaDelBarrio'', doubles as a DisabledLoveInterest for a certain boy named Nandito. The scene where the BigBad [[LargeHam Soraya]] threatens poor Alicia for kissing Nandito while screaming "MALDITA LISIADA!" ("Goddamned crippled bitch!") and then throws her off her wheelchair is so [[{{Narm}} ridiculous and overacted]] that it has reached MemeticMutation levels.

* ''Series/KyleXY'', [[GenderBlenderName Andy]] is sick with cancer.

* ''Series/TheXFiles'': Scully takes on this role for one season after it is revealed that [[spoiler: the tests preformed on her during her abduction have left her with (probably terminal) cancer.]] In accordance with the conventions of the trope, her appearance is relatively unaffected by the illness, and the only visible symptom is a [[spoiler: ''{{Deadly Nosebleed}}''.]]
** In the episode "Hell Money", Kim, the daughter of a Chinese immigrant, is this. Her condition drives her father to [[spoiler: play a game run by [[TheTriadsAndTheTongs Triads]] where he must bid [[OrganTheft his organs]]]].

* ''Series/{{Charmed|1998}}'': The episode "Awakened" revolves around Prue and Phoebe discovering that Piper is terminally ill with the disease Oroya Fever. While real life symptoms of Oroya Fever include being covered in warts and rashes, Piper only experiences coughing, exhaustion, and fainting, all done adorably. [[spoiler: Being the main character, Piper survives, but not until after the crying and good-byes.]]
* In ''Series/DarkMatter'', both Two and Three turn out to have had girlfriends before the crew's total memory wipe who had to put in stasis because they were succumbing to fatal conditions. In Sarah (Three's lover)'s case, it was due to a substance from Ferrous Corp's mining operations polluting the planet where she lived. Sarah dies in "Episode Seven" after she's brought out of stasis and her pod loses power due to [[ShapedLikeItself the killer android trying to kill everyone]], but it's later revealed that Five saved her as a VirtualGhost. Dr Shaw (Two's lover) is given an injection of Two's new advanced nanites after she's revived in the episode "Built, Not Born" and is healthy when she and the crew part ways at the end of the episode, but the series is cancelled before we learn if it will be permanent (she'd had an injection of Two's old nanites before in the backstory, and it had only been a temporary fix). Sarah is transferred to an android body in the same episode.

* ''Series/{{Merlin|2008}}'': Happens frequently with Morgana, most notably in ''A Remedy To Cure All Ills'' in which the MonsterOfTheWeek deliberately makes her sick in order to heal her and so win King Uther's trust.

* Mary of ''Series/SecondChance2016'' is terminally ill with cancer (or implied to be, as she mentioned that her chemo stopped working). However, because of her [[AmbiguousDisorder mentally-off]] brother, Otto, she goes so far as to revive and clone a person to fight her cancer.

* ''Series/{{Firefly}}'':
** A perfect example is found in the story of [[TheWoobie River Tam]], a young woman who is a [[AxCrazy schizophrenic]] [[TheEmpath empath]] as a result of [[MindRape extensive neurological modification/experimentation]] done to her by a shadowy, government-affiliated military research facility. Her older brother, [[TheMedic Simon]], [[BigBrotherInstinct gives up his life as a successful doctor and makes them both federal fugitives when he breaks her out of captivity. The siblings are forced to live on the outskirts of society in order to avoid capture, and Simon spends much of his time and resources in his efforts to find a treatment to help restore River to her former self.]]
** In true Ill Girl fashion, it is also implied that there's no ''real'' possibility for River to ever be cured of her insanity; the best that can be done is short-term chemical treatments, as the damage to her brain is extensive and her body eventually rejects any drugs used to help her. Even after the events of TheMovie, it's not made clear whether she's fully healed or has only partially recovered.
** WordOfGod adds [[spoiler:Inara Serra, resident [[HookerWithAHeartOfGold Oiran]].]]
** Jayne Cobb faithfully sends money home to treat his ill brother Mattie's damp lung disease.

* Parodied in an episode of ''Series/BigTimeRush''. Logan, the band's resident HollywoodNerd, decides to become cooler by creating a "swagger" app which teaches him how to be popular and fun. James, the PrettyBoy of the group, naturally has a high level of swag...but as Logan becomes more and more awesome, he inadvertently [[VampiricDraining sucks the coolness directly out of James]], leaving him physically weak and sickly. It's all PlayedForLaughs, especially when Logan decides he doesn't like being cool anymore and deletes the app, which somehow immediately returns James to normal.

* ''Film/{{Hawking}}'': Portrays the 21-year-old Stephen Hawking as more of a very smart IllBoy than a GeniusCripple, unlike conventional depictions of Hawking as an older man.

* ''Jappening con Ja'': In this Chilean humor show, there was a sketch named "El Enfermito" ("The Ill Dude"). It had [[NoNameGiven an unnamed adult man]] permanently bedridden and hospitalised due to an unexplained SoapOperaDisease, and HilarityEnsues ([[CringeComedy in a way]]) whenever his friends drop by to visit him. [[NotFunnyAnymore It's not as funny now]] due to the ''actor's'' own health taking massive hits through the years, which eventually killed him.

* The LittlestCancerPatient from the ''Series/LawAndOrderSpecialVictimsUnit'' episode "Sick," who is dying of leukemia. [[spoiler: It's then revealed that she's actually dying of mercury poisoning--and her ''grandmother'' is responsible, simply so she can [[MunchausenSyndrome get sympathy from everyone else]].]]

* ''Film/{{Hawking}}'': Portrays the twenty one year old Stephen Hawking as more of a very smart IllBoy than a GeniusCripple, unlike conventional depictions of Hawking as an older man.

** Danny's asthma causes some characters to perceive him as weak - to this day Charlie is constantly worrying about him and trying to keep her promise to watch over him. Justified given that this is a lawless, unforgiving CrapsackWorld and other than plant-based medicines there's not a lot that can restore his breathing if he has an attack. In "[[Recap/RevolutionS1E3NoQuarter No Quarter]]", Danny also uses this to his advantage, to get the drop on the mook Private Richards who's been harassing him.

* [[OurAngelsAreDifferent Castiel]] of ''Series/{{Supernatural}}'' becomes one near the end of season 9, due to [[spoiler:the Grace he stole from another angel slowly burning out]]. By the start of season 10, he's progressed to an IncurableCoughOfDeath and is exhausted most of the time. Tellingly, he was even involved in a NoodleIncident in which he not only failed to keep a demon from hurting Sam, but apparently didn't or wasn't able to [[HealingHands heal Sam]] afterwards.

** [[WordOfGod revealed]] adds [[spoiler:Inara Serra, resident [[HookerWithAHeartOfGold Oiran]].]]