History BigNo / AnimeAndManga

** In ''Manga/LittleButterfly'' Kojima pushes his boyfriend Nakahara off with this whenever a makeout session gets too intense and it looks like [[CoitusEnsues sex might happen]]. Needless to say, this happens quite a lot.

* In ''LightNovel/{{Orphen}}'', none other than [[spoiler:Azalie]] lets out a '''massive''' one when [[spoiler: Flameheart kills Bloody August and destroys Childman's body right when Orphen was about to undo the spells on all of them.]]

** In ''Manga/TheTyrantFallsInLove'', the homophobic Souichi does this whenever his [[SempaiKouhai lab assistant]] Morinaga comes onto him. Matters are confused because he doesn't want to face up to his potential homosexuality and so pretends to resist Morinaga to satisfy his own guilt even when he secretly wants to have sex - the BigNo comes out when he ''really'' doesn't want it and needs to make that clear.

** In ''Manga/TheTyrantFallsInLove'', the homophobic HotScientist Souichi does this whenever his [[SempaiKouhai lab assistant]] Morinaga comes onto him. Matters are confused because he doesn't want to face up to his potential homosexuality and so pretends to resist Morinaga to satisfy his own guilt even when he secretly wants to have sex - the BigNo comes out when he ''really'' doesn't want it and needs to make that clear.

* Used in ''LightNovel/TrinityBlood'' at the climax of episode 22.
* Recently in ''Anime/YuGiOh5Ds'' there was Yusei's BRUNOOOOOOOOOOOOOOOOOOOOOOO!!!
** Actually, he has two of them. In the same episode.

*** And yet again [[spoiler:when she realizes she got both [[RedShirt Miranda]] and [[MentorOccupationalHazard Zola]] killed because of her own cowardice. In the same episode, she lets out another one when the [=DRAGON=] who killed Zola is about to [[EatenAlive eat her alive]]. She survives thanks to an EleventhHourSuperpower awakening, and after that, she no longer does it.]]

** After [[FallenPrincess Princess Angelise Ikaruga Misurugi]] is outed as a Norma (a person unable to use the Light of Mana), she furiously attacks the authorities trying to arrest her with a sword. Her mother, the Empress, jumps in front of her and [[TakingTheBullet is shot in the heart saving her]]. In the English Dub, she lets out a shrill "MOTHER, NOOOOOO!" when the Empress [[DiedInYourArmsTonight dies in her arms]].

*** And yet again [[spoiler:when she realizes she got both Miranda and Zola killed because of her own cowardice. In the same episode, she lets out another one when the [=DRAGON=] who killed Zola is about to [[EatenAlive eat her alive]]. She survives thanks to an EleventhHourSuperpower awakening.]]

** And yet again [[spoiler:when she realizes she got both Miranda and Zola killed because of her own cowardice. In the same episode, she lets out another one when the [=DRAGON=] who killed Zola is about to [[EatenAlive eat her alive]]. She survives thanks to an EleventhHourSuperpower awakening.]]

** And yet again [[spoiler:when she realizes she got both Miranda and Zola killed because of her own cowardice.]]

** The English Dub presents us with Suzaku's epic "[[https://www.youtube.com/watch?v=gJX-YTPZVH4 (g)NOOOOOOOOO(me)!]]" [[spoiler: when his currently BrainwashedAndCrazy LoveInterest, Euphemia li Britannia, is gunned down by Lelouch right as he arrives on the scene.]] He immediately flies into an UnstoppableRage and barges even past the Guren [=MKII=] with his Lancelot [[spoiler: to grab the mortally wounded Euphemia and get her out of there.]]

* In ''VisualNovel/{{Air}}'' when [[spoiler:[[TearJerker Misuzu dies,]] her mother figure]] shouts out her name in this fashion ([[spoiler:"MISUZUUUUUUUU!"]]).

** IllGirl Hayate has a huge, primal one near the end of the second season. Considering how it punctuates a particularly nasty BreakTheCutie moment, the overall effect is quite chilling.

** The English Dub presents us with Suzaku's epic "[[https://www.youtube.com/watch?v=gJX-YTPZVH4 (g)NOOOOOOOOO(me)!]]" [[spoiler: when his currently BrainwashedAndCrazy LoveInterest, Euphemia li Britannia is gunned down by Lelouch right as he arrives on the scene.]] He immediately flies into an UnstoppableRage and barges even past the Guren [=MKII=] with his Lancelot [[spoiler: to grab the mortally wounded Euphemia and get her out of there.]]

** The English dub presents us with Suzaku's epic [[https://www.youtube.com/watch?v=gJX-YTPZVH4 (g)NOOOOOOOOO(me)!]]

* In ''Manga/KOn'', Mio lets out one of these after her on stage... accident. Involving a "[[PantyShot bowl of rice]]".

* In the first episode of ''Anime/FutureGPXCyberFormula ZERO'', Asuka lets one out when she sees Hayato lying down on the ground with his car completely destroyed after his car crashed down from the track with him in it at the English Grand Prix.

* Though the series engages in more and more towards the end, the biggest of Big Noes in ''Anime/NeonGenesisEvangelion'' are one by Asuka [[spoiler:at the end of [[https://www.youtube.com/watch?v=VJ0doO3VFjc her]] [[https://www.youtube.com/watch?v=cM-OOy9jc04 Mind Rape]]]], one by Shinji after [[spoiler: realizing his Mecha has been used by his father to crush the Entry Plug loaded with his unconscious best friend]], another for Shinji after [[spoiler:seeing that the MP-Evas have murdered and EATEN Asuka alive]] and one by Maya Ibuki (who spends most of ''End of Evangelion'' freaking out) after [[spoiler:[[FanNickname Giant Naked Rei]]'s hand passes right through her entire body]]. Some of these were dubbed into English as inarticulate yells, probably to avoid being straight-up {{Narm}}.

* ''Anime/SenkiZesshouSymphogear G'' sees [[TheHero Hibiki Tachibana]] give a Sharp Chigau[[note]]"That's wrong!"[[/note]] in the penultimate episode to the way the antagonists constantly call her a [[InsistentTerminology "human-relic fusion specimen"]].
--> '''Maria:''' "Out of my way, Human-Relic Fusion Specimen One!"
--> '''Hibiki:''' "No! [[MyNameIsInigoMontoya I'm Hibiki Tachibana, age 16!]] [[ItIsDehumanizing I'm not some "fusion specimen!"]] I'm just Hibiki Tachibana, and I came here to talk to you!"

* ''Anime/{{Pokemon}}'':

** Mars has one when [[spoiler:Cyrus throws himself into the new universe Dialga and Palkia have created just as it's starting to disappear.]]

** Earlier in the same season (in the original and English dub), Bulma let out one upon learning that [[spoiler:Vegeta had been killed by Buu]].

** In the dub, Trunks seemed to have mastered the Narm of the Big No, with lines like "If they let that android free, it will be the end of all of us! NOOOOOOOOOOOOOO!" (Lampshaded in this fanvid: https://www.youtube.com/watch?v=_HOAETv_nVo) and not too long after "FATHER! hurgh, NOOOOOO! FATH-ER!"
** But Trunks also has a decidedly non-narmy Big No in the dub of his OVA when he finds Future Gohan dead. In the original Japanese, it's a simple SkywardScream.
** Earlier than the other times, Goku lets out one of the biggest Big Nos ever: [[spoiler: after defeating Frieza on a crumbling Namek, Goku tries to escape on Frieza's ship, but unfortunately, the ship was damaged and plummets into a fissure to dissolve in lava, leaving our hero with no way to escape.]]
** Goku uses instant transmission to do a point blank kamehameha on Cell [[https://www.youtube.com/watch?v=eg1bCXFLKdY here]].
** Let's not forget Jeice's TWO Big Nos for the price of one when he realizes Vegeta is going to kill him late in the Frieza Saga.

* ''Manga/RosarioToVampire'': Kurumu in chapter 41 of the second manga season. See it [[http://www.mangareader.net/rosario-vampire-ii/41/18 here]] and [[http://www.mangareader.net/rosario-vampire-ii/41/25 here]].

* ''Anime/SenkiZesshouSymphogear G'' sees [[TheHero Hibiki Tachibana]] give a Sharp Chigau[[note]]"That's wrong!" in the penultimate episode to the way the antagonists constantly call her a [[InsistentTerminology "human-relic fusion specimen".

* ''Anime/MazingerZ'': Kouji Kabuto, right after his grandfather dies in his arms: "GRANDPA! NOOOOOOOOOOO!!!"
** ''Anime/GreatMazinger'': Tetsuya, after realizing [[spoiler:his adoptive father had pulled out a kamikaze attack to save his life]]: "NOOOOOOOOOOOOOOOOOOO!!!!!!!"
** ''Anime/UFORoboGrendizer'': Duke Fleed after watching [[spoiler:several hundred children being murdered by the Vegans]]: "NOOOOOOOOOOOOO!!!!!"
** A variant in ''Anime/ShinMazinger'': Both Dr. Hell and Tsubaki both cry out "YAMEROOOOOOO!"[[note]]"STOP!"[[/note]] just as Kouji performs the Big Bang Punch. [[spoiler:Doing so ended up freeing Baron Ashura and ushering in TheEndOfTheWorldAsWeKnowIt.]]
* Used straight in ''Roleplay/RecordOfLodossWar'' by two characters at the same time.
* Used in ''LightNovel/TrinityBlood'' at the climax of episode 22.
%% * ''Anime/SonicX'':
%% ** Used at the climax of episode 3 by Amy Rose, Sonic's self-appointed "girlfriend".
%% ** Shadow the Hedgehog does this in episode 61 while trying to defeat the Metarex ship.
* The English dub of ''VisualNovel/{{Kanon}}''(2006) has the young Yuichi screaming "NOOOOOOOOOO!" after [[spoiler: Ayu falls off a tree and apparently dies (she actually slips into a [[ConvenientComa coma]]). In the Japanese version Yuichi instead screams "[[SayMyName AYUUUUUUUUUU]]!"]]
* Though the series engages in more and more towards the end, the biggest of Big Noes in ''Anime/NeonGenesisEvangelion'' are one by Asuka [[spoiler:at the end of [[https://www.youtube.com/watch?v=VJ0doO3VFjc her]] [[https://www.youtube.com/watch?v=cM-OOy9jc04 Mind Rape]]]], one by Shinji after [[spoiler: realizing his Mecha has been used by his father to crush the Entry Plug loaded with his unconscious best friend]], another for Shinji after [[spoiler:seeing that the MP-Evas have murdered and EATEN Asuka alive]] and one by Maya Ibuki (who spends most of ''End of Evangelion'' freaking out) after [[spoiler:[[FanNickname Giant Naked Rei]]'s hand passes right through her entire body]]. Some of these were dubbed into English as inarticulate yells, probably to avoid being straight-up {{Narm}}.
** Since the Japanese word usually used for the Big No, "iya," sounds like a scream anyway, it only makes sense to translate these as such.
* Used in ''Anime/NadiaTheSecretOfBlueWater'' by the title character, twice in the final episode [[spoiler:first when Emperor Neo sacrifices his life to free her from Gargoyle's control, and, even more heartbreakingly, when Gargoyle kills Jean by making him fall to the floor. (Nadia eventually revives him with the Blue Water.)]]
* In ''Anime/DigimonAdventure'', [[spoiler:Hikari does one when Wizardmon "dies", leading to the activation of her crest]]. It was strangely cut from the dub. Equally as strange, the clip was shown in a brief flashback in a later episode, except during a voiceover narration, so her voice was not heard.
** Also used in the episode "Ogremon's Honor" by Mimi when [[ItWasHisSled Leomon "dies"]][[note]]With the exception of Savers, Digimon don't actually "die", exactly. They just get reconfigured. They are computer data, after all.[[/note]]
* ''Manga/LiarGame'' plays this straight with Ms. Kosaka upon her [[http://www.onemanga.com/Liar_Game/82/15/ defeat]].
* ''Anime/MyHime'' has more than a few instances of this happening. Of course, what with all that's going on in that series (especially later on), the characters can be forgiven for yelling {{Big No}}s.
* ''Franchise/LyricalNanoha'':
** IllGirl Hayate has a huge, primal one near the end of the second season. Considering how it punctuates a particularly nasty BreakTheCutie moment, the overall effect is quite chilling.
** In the fourth Megami sound stage, Shamal gives one in a more light-hearted moment when [[spoiler:Agito]] inadvertently shows Hayate a cake from Nanoha's parents' cafe that was supposed to be a surprise (as part of celebrating the tenth anniversary of Hayate recovering) due to being unable to read the kanji on the box.
** Fate has one in the one-shot "[[HasTwoMommies Second Mother's Day]]," when she worries that when Vivio doesn't give her a gift for Mother's day, she will soon stop seeing her as a mother and eventually no longer recognize her.
** [[SmugSnake Quattro]] gets one of these off just seconds before [[MamaBear Nanoha's]] DungeonBypass WaveMotionGun utterly frags her.
* In a mid-series episode of ''Anime/MobileSuitGundamWing'', Duo gives one out when Trowa destroys his Gundam[[note]]As part of an IfYoureSoEvilEatThisKitten situation[[/note]]. It's even bigger in the US dub; voice actor Creator/ScottMcNeil has said in order to achieve this, he thought about the time his wife ran over his motorcycle with the family minivan. It's actually so famous that he's often asked to re-enact it at conventions.
* In ''Anime/{{Robotech}}: [[WesternAnimation/RobotechTheShadowChronicles The Shadow Chronicles]]'' there are two moments - first when [[spoiler: Commander Tailor dies]] and then when [[spoiler: Alex Romero sacrifices himself. This one is especially strong.]]
* Simon from ''Anime/TengenToppaGurrenLagann'' performs a variation on this trope, instead shouting "[[spoiler:ANIKI!!!]]" when he believes [[spoiler: Kamina has been killed by Thymilph. Kamina, however, stays alive just long enough to make a HeroicSacrifice in the form of the Giga Drill Breaker]].
** The king (or rather, queen) of this trope is - surprise, surprise - Kinon. [[spoiler:When Rossiu is about to shoot himself in the head, [[LoveInterest Kinon]] screams out a teary '''''DAAMEEEEEEEEEEE!!!''''' which stops him dead in his tracks - just in time to receive a GetAHoldOfYourselfMan punch from Simon.]]

* ''Manga/{{Bleach}}'':
** Kon does one in episode 15.
** In anime episode 79 (the Bount arc), Uryu Ishida has one after Yoshino is killed.
** Shinji does this in the flashback (Turn Back the Pendulum) arc.
** In anime episode 217, Charlotte Cuuhlhourne does one just before he's killed by Yumichika's sword.
** In anime episode 271, Orihime Inoue does one right after Ulquiorra fires a cero blast into Ichigo Kurosaki, leaving a huge hole in his chest and apparently killing him. In its original manga rendition (chapter 349), it spans '''two pages''' and she even needs to take a breath before continuing with it.
** Toshiro Hitsugaya in chapter 392 when he realizes he's stabbed [[spoiler:Momo and not Aizen in the chest.]]
** In manga chapter 459, [[spoiler:Ichigo Kurosaki when Kūgo Ginjō steals his Fullbring.]]
** An arrancar girl does this when [[PsychoLesbian Chizuru]] makes perverted advances towards her in the anime.
** [[AdaptationExpansion In the anime]], when [[spoiler: Riruka in Rukia's body]] sees a maddened [[spoiler: Tsukishima]] attack [[spoiler: Ichigo]], she shouts "NOOOOOO!" and [[spoiler: uses Rukia's body to propel herself there, then switch into her own body [[GoThroughMe to stop him]].]]
* ''Manga/SailorMoon''. A lot, but particularly in the last episodes of the first and last seasons when all her friends [[spoiler:seemingly die]].
** In the first episode of the second season, ''R'', Usagi screams this as Luna restores her memories so that she can become Sailor Moon again to fight the new threat of the Makai Tree Aliens.
** In one episode of Sailor Moon S, we see the light go out in [[spoiler:Sailor Uranus']] eyes after a long and labored speech about needing Sailor Moon to complete their mission. Usagi gives a particularly heart-wrenching scream.
* In ''Anime/CodeGeass'', Lelouch has one when he loses a life-or-death game of chess to [[PsychopathicManchild Mao]] -- and the life on the line was [[BigBrotherInstinct Nunnally]]. [[spoiler:Though as it turns out, she was perfectly safe and he [[MagicalEye Geassed]] himself for some EnforcedMethodActing.]]
** The English dub presents us with Suzaku's epic [[https://www.youtube.com/watch?v=gJX-YTPZVH4 (g)NOOOOOOOOO(me)!]]
* ''Manga/FushigiYuugi'' makes use of this trope through Miaka, Tamahome, Miaka, Chichiri, Miaka, Yui, Miaka...
* ''Anime/DragonBallZ'':
** Super Buu's Big No [[spoiler:rips a hole in a dimension.]]
** Earlier in the same season (in the original and English dub), Bulma let out one upon learning that [[spoiler:Vegeta had been killed by Buu]].
** Even earlier, in the dub only (he screams "Goku" in the original), Krillin uses one when it becomes clear that [[spoiler:Goku is going to sacrifice himself to take Cell away]].
** In the dub, Trunks seemed to have mastered the Narm of the Big No, with lines like "If they let that android free, it will be the end of all of us! NOOOOOOOOOOOOOO!" (Lampshaded in this fanvid: https://www.youtube.com/watch?v=_HOAETv_nVo) and not too long after "FATHER! hurgh, NOOOOOO! FATH-ER!"
** But Trunks also has a decidedly non-narmy Big No in the dub of his OVA when he finds Future Gohan dead. In the original Japanese, it's a simple SkywardScream.
** Earlier than the other times, Goku lets out one of the biggest Big Nos ever: [[spoiler: after defeating Frieza on a crumbling Namek, Goku tries to escape on Frieza's ship, but unfortunately, the ship was damaged and plummets into a fissure to dissolve in lava, leaving our hero with no way to escape.]]
** Goku uses instant transmission to do a point blank kamehameha on Cell [[https://www.youtube.com/watch?v=eg1bCXFLKdY here]].
** Let's not forget Jeice's TWO Big Nos for the price of one when he realizes Vegeta is going to kill him late in the Frieza Saga.
** At the end of ''Anime/DragonBallZResurrectionF'', [[spoiler:Frieza has a particularly bad one once he's back in his IronicHell and the fairies welcome him back to his tree.]]
* ''Manga/SayonaraZetsubouSensei'' subverts this by having one of the girls peep on their (male) teacher, and when they knock over the privacy wall and each side gets a good eye-full of the other, only he {{screams|LikeALittleGirl}}, much to his consternation.

* In the first ''Anime/InuYasha'' movie (both the English and Japanese versions) Kagome lets out a rather chilling one after [[spoiler:being forced to shoot Inuyasha by the BigBad]] Complete with lack of BGM and echoes. It is used rather effectively though.

* At the end of the first ep of ''Manga/NyanKoi'', Junpei lets out one in its full Engrish glory.
* In the manga version of ''Manga/{{Pretear}}'', Himeno lets out a Big No when she realizes that her carelessness has led to [[spoiler:Shin's life being drained away]].

* The sixth volume of the ''Manga/KingOfThorn'' manga devotes a full page to a Big No [[spoiler:by Shizuku when Kasumi dies]].

* In ''Anime/TransformersArmada'', Optimus Prime lets out one when [[spoiler:Smokescreen]] is killed.
* ''Anime/SCryed'' has the main character, Kazuma, shouting this trope involving the death of a character.
* In episode 11 of ''Anime/GhostStories'', Satsuki yells this when her brother says he put a CreepyDoll in the trash can and she remembers when the doll called her to say it's at the trash can.

* In season 2, episode 6 of ''Manga/GirlsBravo'', a cross-dressing Yukinari screams this at one point.
* Melfina of ''Manga/OutlawStar'' screams "NO!" in episode 17 which stops Harry's [[MindRape hacking attempt]] on her.
* In chapter 52 of ''Manga/FutureDiary'' Yukiteru does this when [[spoiler: Yuno asks him to kill her]].
* In the final scene of the last episode of ''{{Anime/Monster}}'' we are treated to a flashback of Nina's and Johann's childhood where their mother is [[spoiler: forced to give one of them up for an experiment.]] The two hold onto their mother's hand begging her not to let go, and their mother hesitates [[spoiler: before handing over Nina]] who proceeds to scream "No!" in horror as [[TearsOfFear tears]] spring from [[spoiler: her]] eyes.
* ''Anime/{{Gankutsuou}}'': Victoria Danglars does this in the 8th episode before fainting.
* ''Anime/HaloLegends'': Specifically in ''The Duel'', where Fal [[spoiler: discovers the dead body of his wife and lets out his "NOOOOOOOOO"]].
** His inflection makes it a bit difficult to tell, but it seems more like an inarticulate SkywardScream.
* Used in ''Manga/{{Karin}}'' (also called ''Chibi Vampire'') in conjunction with BigOMG when Winner sees his most recent test score. [[https://www.youtube.com/watch?v=6dJ-C-1Hrw0 Link]]
* In ''Manga/HidamariSketch'', Miyako seems to inspire a number of these.
* ''Manga/ZatchBell'': Golden Gash/Zatch Bell has [[https://www.youtube.com/watch?v=ylrtHz4qgO0#t=0m11s this]].
** Similarly, there's [[TransformingMecha Coral Q]], who responds to being hit by ''any'' attack with an enormous [[LargeHam "NOOOOOOOOOO!"]]

* A majority of the regular cast in episode 10 in the ''Anime/AirGear'' anime let out a huge "NOO!!!!" after Akito kisses [[EvenTheGuysWantHim Ikki]].
* ''Manga/RosarioToVampire'': Kurumu in chapter 41 of the second manga season. See it [[http://www.mangareader.net/rosario-vampire-ii/41/18 here]] and [[http://www.mangareader.net/rosario-vampire-ii/41/25 here]].
* In the first episode of ''Anime/FutureGPXCyberFormula ZERO'', Asuka lets one out when she sees Hayato lying down on the ground with his car completely destroyed after his car crashed down from the track with him in it at the English Grand Prix.
* In ''VisualNovel/{{Air}}'' when [[spoiler:[[TearJerker Misuzu dies,]] her mother figure]] shouts out her name in this fashion ([[spoiler:"MISUZUUUUUUUU!"]]).
* In ''Manga/DestinyOfTheShrineMaiden'', Himeko releases two when [[spoiler: Chikane rapes her]]. The English is [[https://www.youtube.com/watch?v=16FX8vgMurE&feature=related even better]].
* ''Manga/PrincessPrincess'': Sayaka in episode 7 after [[HoYay Yuujirou kisses Tooru]].
* ''Webcomic/HetaliaAxisPowers'': Chibitalia when HRE tries to make him a part of the Holy Roman Empire.
* ''Anime/RomeoXJuliet'': Juliet when [[ItWasHisSled Romeo dies]].
* ''Manga/DawnOfTheArcana'': Nakaba wakes up screaming this when she has a dream foreseeing Caesar getting killed. She has another one when her hair is dyed black.
* ''Manga/DailyLivesOfHighSchoolBoys'': Hidenori had one in his InternalMonologue when [[WrongGenreSavvy the literature girl]] is sitting next to him again. Why? She's projecting the image of her novel's male protagonist onto him, which weirded him out.
* In ''Manga/TokyoMewMew'', Ichigo's boyfriend screams this when Ichigo is about to be kissed by Quiche and Ichigo screams this as well before knocking Quiche away.
* ''Manga/MagicKnightRayearth'': Princess Emeraude releases one when [[spoiler:Zagato dies in a battle with the Magic Knights.]]
* Happens in a couple of Hinako Takanaga's works:
** In ''Manga/TheTyrantFallsInLove'', the homophobic HotScientist Souichi does this whenever his [[SempaiKouhai lab assistant]] Morinaga comes onto him. Matters are confused because he doesn't want to face up to his potential homosexuality and so pretends to resist Morinaga to satisfy his own guilt even when he secretly wants to have sex - the BigNo comes out when he ''really'' doesn't want it and needs to make that clear.
** In ''Manga/LittleButterfly'' Kojima pushes his boyfriend Nakahara off with this whenever a makeout session gets too intense and it looks like [[CoitusEnsues sex might happen]]. Needless to say, this happens quite a lot.
* ''Manga/CardCaptorSakura'': Meiling lets out one when Syaoran is injured by The Shot, which she accidentally released.
* In ''Manga/ShadowStar'': Hiroko understandably lets one out as [[spoiler:[[AlphaBitch Aki Honda]] and her GirlPosse are ''raping her with a test tube'']].
* In ''Anime/MawaruPenguindrum'' Ringo does this as a drugged up Tabuki chases her.
* In ''Manga/{{Naruto}}'' Izumo yells this in his mind [[spoiler: a few seconds before Hidan kills Asuma.]]
* During the traumatic end of the first episode of ''Manga/AttackOnTitan'', Eren Yeager lets loose with a big ''"YAMEROOOOOOOOOO!"'' [[note]]"STOP IT!"[[/note]] as [[spoiler:his mother is about to get eaten by the Smiling Titan]]. In the manga and the English dub, this scene is served with a proper BigNo.

* In the first episode of ''Manga/IsTheOrderARabbit'', Tippy does one when Cocoa is holding him too long. At first she's confused by it, but Chino tries to play it off as ventriloquism. However, Tippy is later revealed to be [[TalkingAnimal able to talk]].
* In the anime version of ''Manga/JoJosBizarreAdventure'', during [[spoiler:Caesar's death scene]], Joseph [[https://www.youtube.com/watch?v=VsJeQWZqCpU&t=29s adds in]] a BigNo in GratuitousEnglish after a SayMyName moment.
* In ''LightNovel/{{Orphen}}'', none other than [[spoiler:Azalie]] lets out a '''massive''' one when [[spoiler: Flameheart kills Bloody August and destroys Childman's body right when Orphen was about to undo the spells on all of them.]]
* In ''Anime/GuiltyCrown'', [[spoiler:Mana Ouma does it twice. The first is when she caused the Lost Christmas outbreak, and the second time happens in the final episode]].
* Erza when [[spoiler:Simon dies]] in ''Manga/FairyTail''.
** Natsu when [[spoiler:he loses Igneel]] in episode 264 English Dub.
* In ''Anime/IkkiTousen Dragon Destiny'', an anguished [[spoiler: Kan'u]] screams "NO!" and follows it with [[spoiler: Ryuubi]]'s [[SayMyName name]] towards the end, when [[spoiler: Ryuubi is fully taken over by her SuperpoweredEvilSide.]]
* In ''Manga/Brave10'', Sasuke gives a very vehement one after Kamanosuke asks him if he could skin his weasel Amaharu.
* Bindi and Ricky in ''Manga/ResidentEvilTheMarhawaDesire'' each does this once upon seeing someone close to them dying. [[OcularGushers Many tears ensue]] in both cases.
* During the SchoolFestival, Ao of ''Manga/AsteroidInLove'' lets out this when her mother Shiori tries to take photos of her in {{meido}} outfit the the Earth Science Club's booth.
* ''Anime/{{Tamagotchi}}'': At the end of episode 21b, Kuchipatchi claims to watch his dental hygiene well. Then, when his friends Mametchi and Memetchi leave the room, he says to himself "Not really..." and uses Mametchi's mouth-cam to check to see if he has a cavity. Sure enough, he does, and he lets out a big "NOOOOO-[[VerbalTic TCHI]]!" in his shock.

* ''Anime/MaiHime'' has more than a few instances of this happening. Of course, what with all that's going on in that series (especially later on), the characters can be forgiven for yelling {{Big No}}s.
* ''Franchise/LyricalNanoha''

* ''Manga/FullmetalAlchemist''

* ''Manga/{{Bleach}}''

* ''Anime/DragonBallZ''

* ''Anime/{{Pokemon}}''

* Golden Gash/Zatch Bell has [[https://www.youtube.com/watch?v=ylrtHz4qgO0#t=0m11s this]].

* A majority of the regular cast in episode 10 in the ''Air Gear'' anime let out a huge "NOO!!!!" after Akito kisses [[EvenTheGuysWantHim Ikki]].

* In ''Manga/KannazukiNoMiko,'' Himeko releases two when [[spoiler: Chikane rapes her]]. The English is [[https://www.youtube.com/watch?v=16FX8vgMurE&feature=related even better]].

* ''Manga/AxisPowersHetalia'': Chibitalia when HRE tries to make him a part of the Holy Roman Empire.

* In LightNovel/{{Orphen}}, none other than [[spoiler:Azalie]] lets out a '''massive''' one when [[spoiler: Flameheart kills Bloody August and destroys Childman's body right when Orphen was about to undo the spells on all of them.]]

* Erza when [[spoiler:Simon dies]] in ''Manga/FairyTail''

* ''Anime/SonicX'':
** Used at the climax of episode 3 by Amy Rose, Sonic's self-appointed "girlfriend".
** Shadow the Hedgehog does this in episode 61 while trying to defeat the Metarex ship.