History ArchEnemy / WesternAnimation

* ''WesternAnimation/{{Metalocalypse}}'': Dethklok have Mr. Salacia and Magnus Hammersmith.
** Mr. Salacia is the leader of [[TheConspiracy the Tribunal]], an organization which spies on Dethklok. [[spoiler:In Season 4, Salacia kills TheTeamBenefactor Roy Cornickelson.]]
** Magnus Hammersmith is a former member of Dethklok who seeks revenge against them for kicking him out.

** Mr. Salacia is the leader of an the [[TheConspiracy Tribunal]], an organization which spies on Dethklok. [[spoiler:In Season 4, Salacia kills TheTeamBenefactor Roy Cornickelson.]]

* ''WesternAnimation/Metalocalypse'': Dethklok have Mr. Salacia and Magnus Hammersmith.

* ''WesternAnimation/ChipNDaleRescueRangers'': The Rescue Rangers have [[CatsAreMean Fat Cat]] and [[MadScientist Professor Norton Nimnul]] as their most prominent enemies.

* ''WesternAnimation/PennZeroPartTimeHero'': Penn Zero has Rippen, who trapped his parents in the Most Dangerous World Imaginable.

** Grim has Boogey, his high school bully who continues to torment him in the present. Grim also has Jack O'Lantern, who forced Grim to grant him eternal life centuries ago, [[DoNotTauntCthulhu causing Grim to retaliate]] by [[OffWithHisHead removing Jack's head]].

** Grim has Boogey, his high school bully who continues to torment him in the present.

-->-- ''WesternAnimation/PhineasAndFerb'', My Nemesis.

* ''ArchEnemy/StarWars''

* ArchEnemy/TotalDrama

* ''Franchise/StarWars'':
** ''WesternAnimation/StarWarsTheCloneWars'':
*** Mace Windu to Boba Fett, considering that Mace killed Boba's father Jango in ''Film/AttackOfTheClones'', for which Boba attempts to assassinate him in response. However, Mace has [[UnknownRival no real animosity]] towards Boba and considers killing Jango NothingPersonal.
*** Had the series not been prematurely cancelled, Boba's EvilMentor Cad Bane would have eventually become his new arch-enemy. This is still hinted at in their meeting in ''Series/TheBookOfBobaFett''.
*** Count Dooku to Asajj Ventress, for training her as his personal assassin before casting her aside on Palpatine's orders, attempting to have her killed and later ordering the elimination of her entire people, the Nightsisters. This is further expanded on in ''Literature/DarkDisciple'', where Ventress teams up with Quinlan Vos in an attempt to kill Dooku.
*** Dooku also has a vendetta against Hondo Ohnaka for taking him prisoner and trying to sell him to the Republic. Dooku later retaliates by sending Grievous to to attack Hondo's base and confiscate his arsenal.
*** Ventress also has Savage Opress, her former apprentice who she [[BrainwashedAndCrazy brainwashed]] into killing his own brother Feral. Opress [[TheDogBitesBack rebels against Ventress]] after being fed up with her abuse.
** ''WesternAnimation/StarWarsTheBadBatch'': Clone Force 99 have Tarkin and Rampart. Tarkin has Clone Force 99 (with the exception of Crosshair) branded as traitors for refusing to kill civilians, and later order an orbital bombardment of their homeworld of Kamino, which Rampart carries out.
** ''WesternAnimation/StarWarsRebels'':
*** The Grand Inquisitor to Kanan Jarrus, as the lead agent of the Empire hunting down the Jedi, with whom Kanan has a climactic duel in the Season 1 finale.
*** In Season 2, Kanan gains a new arch-enemy in Maul, who blinds him and seeks to corrupt Kanan's padawan, Ezra, to the dark side, often attempting to kill Kanan due to seeing him as an obstacle to this goal.
*** Aleksandr Kallus to Garazeb Orrelios, as Kallus [[spoiler:seemingly]] led the genocide of Zeb's people, the Lasat. [[spoiler:However, it's later revealed that Kallus did not give the order to use a WMD on the Lasat, and was in fact horrified by the decision. He and Zeb eventually reach an understanding and even become close friends after Kallus makes a HeelFaceTurn]].
*** Darth Vader to Ahsoka Tano, his former Padawan who is opposing the Empire.
*** Grand Admiral Thrawn to Hera Syndulla. Hera is the Captain of the Ghost, while Thrawn is the leader of the Imperial cell dedicated to hunting her and her crew. Though Thrawn respects Hera as a WorthyOpponent, Hera takes great offence to Thrawn invading her homeworld of Ryloth and stealing one of her most sentimental family heirlooms.
*** Thrawn also becomes the arch-enemy of Ezra Bridger, leading the Imperial Garrison on Ezra's homeworld of Lothal and being perfectly willing to harm innocents for the sake of the Empire, while Ezra is a Jedi who prioritises innocent lives over his own goals. While Ezra has to face off against [[GreaterScopeVillain the Emperor]] near the end of the series finale, Thrawn is ultimately the FinalBoss of the series for him.
*** Governor Pryce to Kallus [[spoiler:after his HeelFaceTurn]]. Pryce is one of the most sadistic Imperials, and hates Kallus [[spoiler:for being a traitor]], while Kallus hates Pryce for reminding him of [[spoiler:his former Imperial status and cruelty]].
*** Pryce is also the arch-enemy of Ryder Azadi, having had him arrested so she could steal his job as Governor of Lothal.
** ''WesternAnimation/StarWarsResistance'':
*** Kazuda Xiono has Commander Pyre, a First Order stormtropper officer who he has multiple encounters with. In ''Descent'', Pyre attempts to arrest Team ''Fireball'', which results in Kaz's aquaintance Tam being taking into custody and joining the First Order. Kaz also has Jace Rucklin, who blames Kaz for the destruction of his ship.
*** Tam Ryvora has Agent Tierney, who spends the entirety of her time on ''[[WesternAnimation/StarWarsResistance Resistance]]'' manipulating and trying to corrupt the former.

** Garnet has Yellow Diamond, her former superior who she defies and [[FantasticSlur insults]] in "Message Received", angering Yellow Diamond and effectively making Peridot a traitor to Homeworld. This causes Peridot to suffer SanitySlippage in the following episode, "Log Date 7 15 2". When Peridot confronts Yellow Diamond in "Reuinited", however, Peridot confronts Yellow Diamond again, she [[ButForMeItWasTuesday denies remembering Peridot]] and [[OneHitKill poofs]] her.

** Enzo Matrix is forced to assume the role of Mainframe's Guardian when Megabyte banishes Enzo's idol and predecessor Bob into the Web. [[spoiler:After Megabyte takes over the city of Mainframe, Matrix confronts and defeats Magabyte in one-on-one combat (with a help of a trident [=AndrAIa=] tosses to Matrix).]]

* ''WesternAnimation/ReBoot'': Bob, Dot Matrix, and Hexedecimal have Megabyte.

* ''WesternAnimation/ReBoot'':
** Bob, Dot Matrix, and Hexedecimal have Megabyte.

** Bob has Megabyte, a recurring antagonist who betrays him during the Web War, resulting in Bob being stranded in the Web, and who later impersonates Bob and nearly marries Dot.
** Megabyte also has a violent SiblingRivalry with his sister Hexadecimal, who is the [[OrderVersusChaos Chaos to Megabyte's Order]].

* ''WesternAnimation/ReBoot'': Bob has Megabyte, a recurring antagonist who betrays him during the Web War, resulting in Bob being stranded in the Web, and who later impersonates Bob and nearly marries Dot.

* ''WesternAnimation/ReBoot'': Rob has Megabyte, a recurring antagonist who betrays him during the Web War, resulting in Bob being stranded in the Web, and who later impersonates Bob and nearly marries Dot.

* ''WesternAnimation/SWATKats'': Chance "T-Bone" Furlong and Jake "Razor" Clawson have Dark Kat, as an ill fated confrontation between the duo and Dark Kat led to T-Bone and Razor being discharged from the Enforcers.