Discredited Meme: In-Universe example. One Super Effective comic has a Bug Trainer giving a Gurren Lagann speech to his Beedrill... As Red, standing nearby, rolls his eyes in frustration.
This comic◊ was posted back in 2002, guess who happened to appear in Super Smash Brothers Brawl? The strip also managed to predict Pac-Man and the Duck Hunt Dog's appearances in the series' fourth installment.
This 2008 strip suggests that among the characters left out of Brawl were Ness, Captain Falcon, Jigglypuff, and Mewtwo... any guesses as to which of these characters made it to the final game, class?
This strip becomes a lot funnier since the revelation of Pokémon's seventh generation, in which one of the new Pokémon is a ghost pretending to be a Pikachu.
Scott once got a pornographic fan comic page of Leo and Aeris dropped. He now does pornographic bonus art of them and other characters on Patreon.
There is a Kingdom Hearts-based comic where Leo!Sora proposes they do experiments on Winnie-the-Pooh, and leaves him busted open, with his blood and fluff all over the place, begging Piglet to kill him. When Pooh went into the public domain in 2022, someone conjured up a horror version: Winnie-the-Pooh: Blood and Honey.
Jerkass Woobie: Leo. As much of a Jerkass as he can be, it's kinda hard not to pity him at times, especially with how Aeris sometimes treats him. Most of his "cruelty" is to fictional characters (such as the Sims example) and things like the baby worm tend to be in the context of strips portraying Leo and Aeris as specific fictional characters being parodied, rather than portraying them in the "usual" characterization.
Popular with Furries: Thanks to Leo and Aeris being anthromorphic cats, it's a popular webcomic amongst furries.
Seasonal Rot: The later comics are generally considered to be of lower quality than the pre-2010s comics. The Dethroning Moment of Suck page in particular either has one of the later comics, or had those removed because the troper found a worse comic.
In #110 Bubblegum Leo not only rips his own fur off in an attempt to not suffocate, he then proceeds to chew that hairy glob of gum again. This must be why cats get hairballs so often.
#347: "Tales of Ternaldo" is a relatable example for people who have had social issues and were never asked to join groups in school.
#210 "The Lost Episodes" is a twisted Deconstruction of Tom and Jerry, where Jerry hits Tom in the head with a sledgehammer, leaving Tom a quadriplegic, and resulting in Jerry going to prison. Just to make things worse, both Tom and Jerry look like they’ve been crying.
They Wasted a Perfectly Good Character: To date, Ramsoomair has made three strips parodying Star Fox. The only one to feature any of the characters aside from Slippy (as opposed to having Aeris & Leo fill their roles)? The one where Fox & Falco have sex while making bad in-jokes. And then Wolf shows up, implying it's not over - though one wonders how he got on the Great Fox (or why he has a beer gut, unlike Fox and considering his flight suit implies he'd be pretty well-built out of costume). Then again, yaoi fantasies never had to make sense as it turned out to have been Aeris' imagination. Still, the one time we see Ramsoomair's take on any of the other Star Fox characters, this is what we get.note The other two strips featured Leo as Fox and Aeris as Krystal. Slippy was featured in the second one.
What Do You Mean, It's Not for Kids?: At first, it looks like a cutesy comic about two Funny Animal cats who go on adventures in various video games. However, strong profanity is common and there is explicit sexual humor.