These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
YMMV: Party of Five
Accidental Innuendo: One of Julia and Griffin's first scenes has her talking about stains on his coat. Specifically Julia starts talking about where they possibly could have come from. The line she uses is "you see those little white stains" - she immediately says something about milk but come on, we all know what the first assumption was.
"Funny Aneurysm" Moment: Kirsten's freaking out about her wedding in season 2 is funny. But considering that she ends up suffering from depression in season 3, it now comes across as eerie Foreshadowing.
Harsher in Hindsight: Bailey casually mentions setting a date for his and Sarah's wedding - it's September 11th. If the wedding had happened, it would have been September 11th 2000 meaning their first anniversary would have been...yeah.
Les Yay: Claudia and her friend Jody are a little too close.
Narm Charm: A scene between Julia and Griffin after Jill's death has her buying him a second-hand coat Jill had planned to get for him. Julia starts making up scenarios about where the rips, tears and stains came from. What she says is rather ridiculous and a little silly - yet it has Griffin opening up to her and the scene is rather sweet.
Romantic Plot Tumour: Any romance plot that involves Julia tends to become this. She's guaranteed to have at least two love interests per season. Charlie and Kirsten narrowly avoid this as after they split in season 3, they become Amicable Exes for a while - and they are spared any more romance drama as they get together for good at the start of season 6.
The Scrappy: Julia is the least popular of the leads, mostly due to her inability to not fall for guys who aren't already in relationships. Additionally she seems to get a new gal pal every season, implying she's not particularly good at making long-term friendships.
Seasonal Rot: Seasons 5 and 6 aren't liked too well by the fandom.
Tear Jerker: Many moments to choose from but the most heart wrenching is Claudia's breakdown in front of Bailey at his intervention where she threatens to stop loving him and orders him out of their lives if he doesn't get better.
There's also the episode where each of them confront the man who was responsible for their parents' death. Charlie is the most reluctant to do so, and we find out why at the end; he blames himself. He thinks if he'd come home on time to babysit the others, his parents wouldn't have been in such a rush, and they wouldn't have been hit by the drunk driver.