These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
YMMV: Figure It Out
Accidental Innuendo: Say, you are watching this show as a teenager or a person in their late-teens, and some questions are indeed, indeed accidentally implicating other stuff. Especially in the 2012 revival. Something not that uncommon from the humor used in current Nick shows (iCarly, Victorious) compared to some of the 90s shows some guest panelists were from (for example, GUTS, Nick Arcade, The Mystery Files Of Shelby Woo, etc.)
James Maslow: Did you train a goat to milk itself?
Funny Moments: The episode where Lori Beth took over as host for the first contestant, right down to Summer getting slimed (three times in rapid succession) because she was "Sitting in Lori Beth's seat."
The new version had a recent gem of a contestant named Grennan who was rather smarmy about his talent being guessed. Once it was, he bolted right out of his seat and backstage before he could get slimed (since the last word that completed the puzzle was the Word of Honor). The host had to pretty much drag him back to get slimed (and is, so far, the most Jeff's ever been slimed himself as he restrained the kid to make sure he actually got it).
Harsher in Hindsight: All mention of Amanda being crazy, especailly given how her career had been going on in 2012-2013.
Heartwarming Moments: Pretty notorious in the second season, where some disabled children are selected randomly for constestants in the SSA section of the show, and the panelists if the SSA was so silly or not, play along for them to get a prize.
This is something that just resurfaced recently (as of late 2013), but Danny had mentioned in some podcasts that he played 'chill' and for fun as a panelist, because he was doing his thing for the kids. That is, too, he had some fans in the way of the show, it's cool and completely warming watching his reactions when some of the contestants do some imitations of him and he being surprised and flattered at them.
Anytime a pet was involved in the talent or skill. The manner where Lori Beth and/or Amanda wanted to interact with them is certainly cute.
Hilarious in Hindsight: Danny once mentioning that his fear was singing in front of the stage. This is of course excepting he sung in the "Hard Day's Pete" episode of The Adventures of Pete & Pete, and that Summer mentions he is in a band in a later episode. Skip two or three years later, just after leaving Nickelodeon and dedicating time to College, to now (more than a decade later), and he is indeed STILL in a band, also serving as main vocalist.
Just Here For Panelist X/Slime: Many viewers don't care about the contestants' talents and just want to see their favorite Nick stars and the Secret Slime Action.
Also the Hint alarm... especially when the Charade Brigade of the first series came to the front to help the panelist to get one of many words.
Retroactive Recognition: A five-year-old Hunter Hayes appeared as a contestant on the original series, his talent being a Cajun singer and accordionist. Made even funnier by the fact that Lori Beth even says "Hunter, you're dreamy!"
They Changed It, Now It Sucks: Some fans of the old version have complained that the new version did away with Billy the Answer Head in favor of the "IT Board."
What an Idiot: During the Secret Slime Action, Summer would sometimes ask a panelist (usually Danny) to do something, and s/he usually fell for it. Justified, in that she was the only one onstage who knew about the Action.