Fandom Nod: In "Dance Of The Undead", when asked why the Hex Girls went back to their original outfits (resembling the ones worn in Witch's Ghost), they say that fans just preferred their original look. Some fans complained about their new look, so this is more than likely a little in-joke.
Matthew Lillard, who's played Shaggy before, now provides the voice of Shaggy after the original voice actor for him (Casey Kasem) retired from doing his voice after 40 years of loyal service, though Kasem is still on the show, only now as Shaggy's father.
Speaking of parentage, Brad Chiles, Fred's real father, is voiced by Tim Matheson, the original Jonny Quest.
Screwed by the Network: The first season was split in half and aired over two years. The second season was announced to premiere in May 2012, but the episode was not aired. After it didn't air it was announced that the episode would air on July 10 (almost a full year after the previous episode), but again didn't air. New episodes finally started on July 30, over a full year after the first season ended, and were burned off at 2PM monday-friday for a few weeks and briefly mis-labeled as Tom and Jerry Tales.