Rules are not necessarily sacred; principles are.
"...when Kirk or Picard (or Sisko or Janeway or Archer) is faced with violating the Prime Directive to resolve a crisis, you can usually count on scads of pretentious brooding, circular arguments, and heart-rending shots of suffering natives, culminating in the moment where the Captain defies all logic and everything he stands for by shouting, 'Screw the Prime Directive, I'm going in!'"
"If Snape gets hold of the Stone, Voldemort's coming back! Haven't you heard what it was like when he was trying to take over? There won't be any Hogwarts to get expelled from! He'll flatten it, or turn it into a school for the Dark Arts! Losing points doesn't matter anymore, can't you see? D'you think he'll leave you and your families alone if Gryffindor wins the house cup?"
Huck: It was a close place. I took [the letter giving Jim away] up, and held it in my hand. I was a trembling, because I'd got to decide, forever, betwixt two things, and I knowed it. I studied a minute, sort of holding my breath, and then says to myself: "All right, then, I'll go to hell!"—and tore it up.
"Screw protocol, Reid's in trouble!"
—Prentiss, Criminal Minds, "Amplification"
"I don't care about protocol, I don't care whether we're working this officially. We don't touch any new cases until we find out who did this."
—Hotch, regarding Garcia getting shot, Criminal Minds, "Penelope"
"Those who break laws are scum. And those who abandon their friends to follow the law... they're lower than scum!"
Uhura: Captain, I have orders from Starfleet Command. We're to put back to Spacedock immediately to be decommissioned.
Spock: If I were human, I believe my response would be "go to Hell." [beat] If I were human.
Picard: What I am about to do is a direct violation of our orders. If anyone objects, please do so now. It will be noted in my log.
Data: Captain, I believe I speak for everyone here, sir, when I say... "to hell with our orders".
Sisko: Mr Odo, you're not going to take the law into your own hands.
Odo: The "law"? Laws change depending on who's making them. Cardassians one day, Federation the next. But justice is justice.
—Star Trek: Deep Space Nine, "A Man Alone"
"Well, there's the law and there's what's right. I'm gonna do what's right."
"Troopers! I just received new orders: our superiors say the war is cancelled. We can all go home. Bison is getting paid off for his crimes, and our friends who have died here...will have died for nothing. But, we can all go home. Meanwhile, ideals like peace, freedom, and justice, they get packed up. But, we can all go home. Well, I'm not going home. I'm gonna get on my boat, and I'm going up river, and I'm going to kick that son of a bitch Bison's ass so hard that the next Bison wannabe is gonna feel it! Now, who wants to go home...and WHO WANTS TO GO WITH ME?!"
—Col. William F. Guile, Street Fighter
"I recognize that the council has made a decision. But given that it's a stupid-ass decision, I have elected to ignore it."
"Being legal doesn't make it right."
—Raiden, Metal Gear Rising: Revengeance
"Regardless of the circumstances, we were saved by Ichigo Kurosaki in our time of need. It is now time that we returned the favor. Even if that should require violating our own statutes, to allow such a debt to go unpaid would bring eternal shame upon the entire Gotei."
—Genryūsai Shigekuni Yamamoto, Bleach
Magrat: What's she doing?
Nanny Ogg: I reckon she's going to topple Duke Felmet.
Magrat: But what about the rule about not meddling?
Nanny Ogg: Ah well, see, there's another rule. A more important rule. And Esme's followed it all her life.
Magrat: Which is?
Nanny Ogg: When you break the rules, break 'em good and hard!
"I used to believe that being a good soldier meant doing everything they told you. That's how they engineered us. But we're not droids. We're not programmed. You have to learn to make your own decisions!"
—Captain Rex, Star Wars: The Clone Wars
"Doesn't matter what the press says. Doesn't matter what the politicians or the mobs say. Doesn't matter if the whole country decides that something wrong is something right. This nation was founded on one principle above all else: the requirement that we stand up for what we believe, no matter the odds or the consequences. When the mob and the press and the whole world tell you to move, your job is to plant yourself like a tree beside the river of truth, and tell the whole world - No, you move."