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- In Ghost in the Machine, while a serial killer is undergoing a CAT scan at the hospital, a surge of lightning courses through the building, and his soul is transformed into electrical energy. He then uses the electrical grid and computer networks to continue his killing spree.
- The Exorcist had a variation - as one transcript puts it, a huge machine, two pieces on either side of Regan's head and a piece above
- The mentally ill girl in Dark Floors (the Lordi monster film) is put into a CT machine and shortly thereafter begins to freak out. It's also where she starts when the monsters make the night start over again, something only she can remember.
Live Action TV
- Inverted in Scrubs where Elliot claims she uses a broken MRI machine as her "own little coccoon" when she's feeling stressed. She was surprisingly calm.
- JD meets Alex when he is forced to take care of her while she is stuck in an MRI machine for hours.
- In The X-Files episode "Theef", the poor doctor's poor wife is literally grilled in one of those, as the bad guy microwaves a Voodoo Doll of her.
- One of the challenges in Gaki no Tsukai ya Arahende involves a MRI scan. And has the contestants terrified.
- Kingdom Hospital plays with the Haunted Technology aspect in the episode "Butterfingers." Basically, Maine's most hated baseball player has just been admitted to Kingdom after a suicide attempt (gunshot to the head). After surgery, they want to put him in the MRI for additional testing, but Mrs. Druse protests that it'll send him into Swedenborgian space, from which there is no (known) exit. Fortunately, an incident in which a bullet gets stuck to the machine (It Makes Sense in Context) delays the procedure long enough for Dr. Hook to show up and cancel the MRI, because it would kill the patient... due to the its intense magnetic field interfering with the pacemaker he'd gotten some years earlier.
- A particularly dark Running Gag on House is the MRT machine causing all kinds of violent reactions on the patients placed inside. Not surprisingly, a few episodes have this happening because the patient has some kind of mental imbalance (most probably because of the disease affecting him) which triggers when placed within the machine and makes him have a panic attack.
- In the fifth level of Condemned 2: Bloodshot, Ethan crawls into a CT tube and promptly suffers a hallucination where the SCU headquarters and its agents are taken over by a black slime.
- For many people, claustrophobia is perfectly real, and a CT or MRI tube can easily trigger that. That's why they developed the Open MRI.
- Subverted for others who find small spaces feel more protecting than open spaces.