On a bonus clip for the DVD of The Pirates Who Don't Do Anything, one of Elliot's fears is Buzz-saw Louie. Elliot is played by Larry. In The Toy that Saved Christmas, Larry is standing right next to Louie the first time Louie ever brings out his buzz-saw, and while Louie was perfectly justified in doing so under the circumstances, he didn't warn Larry that he was going to beforehand, and having someone bring out a sharp pointy object right next to you without warning you would be a very nerve-wracking experience. It makes sense he'd appear on a list of things a character played by Larry was afraid of.
In "Sweetpea Beauty," the titular character, played by Petunia Rhubarb, is singing a cute little song about how not so nice or pretty things like bees and mud are useful and are in some way beautiful. Then she sings a line about peeling an onion. In a world populated by sentient vegetables.
In the song Pizza Angel Larry spends the song desiring his Pizza, with TOMATO sauce.
Word of God is that it's okay to eat non-sentient food items; presumably the onions and the tomato sauce weren't sentient.
The "Island of Perpetual Tickling" mentioned in Esther is intended to be a G-rated version of the hangings in the original Bible story, but once you know that there have been at least ten recorded cases in Real Life of people dying of laughter, it doesn't take too long to realize that being banished there would be a very painful way to die.
That one comes up a lot. For example, before the intro song, Larry points out to Bob that he can't play the guitar because he has no hands. One wonders how he can change notes on the tuba...
This can be done by varying your embouchure, although this requires a tremendous amount of facial strength and control for a tuba.
Pa Grape's transition from white trash to Ambiguously Jewish was followed by him primarily appearing in Old Testament episodes (for those who don't know, the Old Testament is the Jewish scripture, known to the Jews as the Tanakh).