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The Spirit does not have any super-powers nor does he have any special training. He is an excellent fighter, and survives mostly on force of will and luck. He works mainly out of Central City (New York City in the first few issues) but often travels internationally. His base of operations is a crypt in Wildwood Cemetery that has been refitted for comfortable living.His costume consists of a blue suit, with white shirt and red tie, hat, gloves and domino mask. Throughout the series he is seen in various states of undress, but he is never seen without the mask, aside from his very first adventure when he was still Denny Colt.
Commissioner Eustace (Diogenes) DolanCommissioner of the Central City Police Department. Friend of Denny Colt. Dolan often competes with The Spirit in solving cases.
Ellen DolanDaughter of Commissioner Dolan and girlfriend of The Spirit. (Though not always according to The Spirit himself). When she was first introduced, she was an upright psychology student with big ol' Nerd Glasses; however, when The Spirit decided to take her glasses off and give her a big smooch, she became considerably less upright.
Ebony WhiteBlack kid sidekick to The Spirit and main provider of comic relief. (He was replaced later in the series by Sammy, a white boy, mainly due to concerns over racial stereotyping.)
The OctopusAs the Arch-nemesis of The Spirit, The Octopus appears more often than any other non-cast member. His face is never seen: it is either obscured or hidden by a disguise. He can always be recognized by his distinctive gloves. His origin would be told, not in the original strip, but in a story penned by Eisner for a comic reprint series put out in the 1960s collecting the old Spirit stories in traditional comic format.
Mr. CarrionCon man who has a pet vulture, Julia.
Gerhard ShnobbleComplete nobody who finds that he can fly.
Hazel P. MacbethWitch with apparent magical powers who often appears in Halloween themed stories.
Silk SatinSpy and potential alternate love interest for The Spirit.
P'GellCrime lord with a "black widow" m.o. who often tries to seduce The Spirit.
Sand SarefDenny Colt's childhood friend who is, in actuality, a spy.
Silken FlossEvil scientist who works with The Octopus.