VIDEOS:
Ryuko gets vaporised painfully
Shadow, having been triggered by Ryuko saying Sayonara (considering that's what Vegeta and Mewtwo said to him before the death blow), proceeds to pin her in place to make sure she can't interrupt him by any means before unleashing a powerful Chaos Blast, which causes her to die and the explosion to consume her and senketsu.
Example of:
No Body Left Behind
Example of:
Pretender Diss