- Keep Circulating the Tapes: Given that the show was presented live in its early years and CBS's network policy of wiping videotapes until late in its run, the show has very few surviving episodes.
- The Other Darrin: Like most soaps, many characters were recast over the years. Notably, the main heroine Vanessa Dale was played by three actresses over the years (most notably by Audrey Peters for most of the show's run).
- Screwed by the Network: Love of Life spent most of its life in the late morning or noon timeslot, where it fared reasonably well until the late 1970s. CBS moved the show to 4:00pm in April 1979; like the previous time slot occupant, Match Game, the show experienced affiliate clearance issues and steep declines in its ratings. The show was cancelled 9 months later in February 1980.
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