Tear Jerker / Mighty Med

• In The Claw Prank Redemption, is full of this. Skylar was given a life draining ability and told to get rid of Oliver, yet she was reluctant to let that happen. What makes it sad is that while Skylar has turned evil and accepted it, there is still a shred of decency left in her, enough to feel regret and sadness before attempting to kiss Oliver so he'll die.
• Skylar dying at the hands of The Annihilator was just heartbreaking. When she flatlined and actually died, Oliver almost cried.