Spider-Man has to take down the slick new villain, Slyde, who is stealing various chemicals from around the city in an effort to create a deadly virus that could wipe out New York.
- Surprisingly Realistic Outcome:
- Following what happened in the "Superior Spider-Man" arc, Max is still furious for the way Peter behaved towards him, even though it was actually Otto in Peter's body saying those words to him. In fact, he refuses to let him back into Horizon High.
- Despite getting help from him in the previous episode, Peter is still bitter towards Otto for ruining his normal life while in his body.
- What the Hell, Hero?: Max tears into Peter over his behavior in the previous episodes.