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* Prior to the final battle of ''Film/ShaolinTemple1976'', the traitorous Master Monk Hui-xian decides to poison all his fellow monks by spiking their breakfast, rendering them helpless and unable to defend themselves when the Manchurian army invades.
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* Prior to the final battle of ''Film/ShaolinTemple1976'', ''Film/TheShaolinTemple1976'', the traitorous Master Monk Hui-xian decides to poison all his fellow monks by spiking their breakfast, rendering them helpless and unable to defend themselves when the Manchurian army invades.
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* Prior to the final battle of ''Film/ShaolinTemple1976'', the traitorous Master Monk Hui-xian decides to poison all his fellow monks by spiking their breakfast, rendering them helpless and unable to defend themselves when the Manchurian army invades.
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* ''Film/SpecialSilencers'' has a ''horrifying'' example; the villain, Gundar, has a bunch of pills that [[{{transflormation}} transforms a person's insides into plants]], and selectively executes his victims by spiking the pills inside their food and beverage. His victims all died from having branches and roots coming out their bodies, ChestBurster-style.
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* In ''Film/{{Beethoven}}'', while entertaining Brad and Brie, who have rubbed the entire Newton family the wrong way, Brad asks for a refill of lemonade. Alice takes the glass, and fills it up, but when no one is looking, she takes a swig, and spits it back in the glass.
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* ''Film/UpTheFront'': When seducing Lurk, UsefulNotes/MataHari sneaks a TruthSerum drug into his drink. However, Lurk catches on and switches the drinks, leading to the two to switch the drinks back and forth until neither know who has the drugged glass. After the two uncertainly take a sip, Mata Hari discovers she has had it.
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* In ''Film/OnTheBuses'', Stan and Jack spike the female bus drivers' cups of tea with Olive's diuretic pills to make them seem unreliable. Blakey ends up drinking a cup of tea meant for Vera and suffers the same effects.
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* ''Film/DoctorInClover'': Sir Lancelot never goes to a hospital party without a flask as it makes the orangeade taste better and makes the nurses friendlier. Dr. Grimsdyke has the same idea, as do Preston and some of the other medical students.
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* ''Film/GuyanaCrimeOfTheCentury'': At one point in the movie, stimulants are dosed into food, with the proportions doubled for sandwiches and soft drinks, under Johnson's orders.
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* ''Film/TheWrestler'':
** [[spoiler:Jules]] gives MJ a green smoothie laced with ergot. MJ, having been forewarned, tosses it in the bin as soon as she is out of sight.
** Randy, in his day job at the deli counter of a local grocery store, encounters a particularly indecisive elderly lady who keeps asking for "a little more" or "a little less" potato salad. Annoyed at her, he discreetly licks a few dips of his gloved fingers as he's disposing of excess. He later on proceeds to cut some meat and intentionally slice his fingers open and bleed on everyone in a ScrewThisImOuttaHere move.
** [[spoiler:Jules]] gives MJ a green smoothie laced with ergot. MJ, having been forewarned, tosses it in the bin as soon as she is out of sight.
** Randy, in his day job at the deli counter of a local grocery store, encounters a particularly indecisive elderly lady who keeps asking for "a little more" or "a little less" potato salad. Annoyed at her, he discreetly licks a few dips of his gloved fingers as he's disposing of excess. He later on proceeds to cut some meat and intentionally slice his fingers open and bleed on everyone in a ScrewThisImOuttaHere move.
to:
* ''Film/TheWrestler'':
** [[spoiler:Jules]] gives MJ a green smoothie laced with ergot. MJ, having been forewarned, tosses it in the bin as soon as she is out of sight.
**''Film/TheWrestler'': Randy, in his day job at the deli counter of a local grocery store, encounters a particularly indecisive elderly lady who keeps asking for "a little more" or "a little less" potato salad. Annoyed at her, he discreetly licks a few dips of his gloved fingers as he's disposing of excess. He later on proceeds to cut some meat and intentionally slice his fingers open and bleed on everyone in a ScrewThisImOuttaHere move.
** [[spoiler:Jules]] gives MJ a green smoothie laced with ergot. MJ, having been forewarned, tosses it in the bin as soon as she is out of sight.
**
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* ''Film/TheKillingKind'': [[spoiler:On realising that Terry is beyond help and that he will undoubtedly kill again, Thelma gives him a glass of [[TrademarkFavoriteFood chocolate milk]] laced with poison and then [[CradlingYourKill holds him in her lap as he dies]].]]
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* Done twice in Disney's ''Film/TheHauntedMansion'' with poison being put into goblets of wine.
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* Done twice in Disney's ''Film/TheHauntedMansion'' ''Film/TheHauntedMansion2003'' with poison being put into goblets of wine.
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* Downplayed and subverted in ''Film/ChildrensPartyAtThePalace''. The Grand High Witch planned to put her potion in the [[UsefulNotes/HMTheQueen Queen]]'s cake that would [[ForcedTransformation turn whoever eats from it into mice]], until she finds out there was no cake to begin with. Eventually the villains bake their own cake with her potion in it...but turns out the potion had no effect on the Goodies.
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* Downplayed and subverted in ''Film/ChildrensPartyAtThePalace''. The Grand High Witch planned to put her potion in the [[UsefulNotes/HMTheQueen [[UsefulNotes/ElizabethII Queen]]'s cake that would [[ForcedTransformation turn whoever eats from it into mice]], until she finds out there was no cake to begin with. Eventually the villains bake their own cake with her potion in it...but turns out the potion had no effect on the Goodies.
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TamperingWithFoodAndDrink in LiveActionFilms.
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* ''Film/TwelveHourShift'': Nurse Mandy offers coffee to the security guard watching over the hospitalized inmate, failing to mention she added morphine.
* Spoofed in ''Film/TheAddamsFamily'': Fester brought some cyanide with him when he moved in, with the implication that he'd poison the family this way. When Morticia finds it, she just smiles and asks if he thought they'd run out of it. The implication is the family uses cyanide as ''seasoning''.
* In ''Film/{{Andhadhun}}'', Simi pours poison into Akash's tea in front of his eyes ([[ObfuscatingDisability he's pretending to be blind]]). [[spoiler:After he "accidentally" spills the tea, he finds out that a sweet he ate earlier was also poisoned.]]
* In ''Film/TheAssassinationBureau'', Eleanora first poisons [[spoiler:her husband Cesare, the Italian assassin]], then prepares drinks for herself and Dragomiloff, slipping poison in his drink. Dragomiloff spins the table until it stops, picks up the goblet in front of him, drinks down the contents, and falls to the floor. [[spoiler:He was faking it.]]
* In ''Film/BattleRoyale'', Yuko Sakaki puts potassium cyanide in spaghetti that Yukie Utsumi's friends cooked for Shuya Nanahara. Yuko then tries to deliver the spaghetti to Shuya personally, but Yuka Nakagawa snatches it away and eats it. [[spoiler:She then suffers from the poisoning, vomits much of her blood out of her mouth, then quickly dies. This results in Haruka, Yukie, Chisato (but ironically, not Yuko) all getting shot by Satomi out of suspicion she can't trust any of the girls.]]
* Johnny from ''Film/TheBigCube'' slips LSD into people's drinks at parties. He's kicked out of medical school after one of his victims runs into traffic and dies. Later, he and Lisa hide LSD inside Adriana's anxiety pills.
* In ''Film/BlindDate'', [[Creator/BruceWillis Walter]] uses a tiny syringe to put alcohol in chocolates he has delivered to Nadia because she has an extreme allergic reaction to alcohol.
* In the early Creator/PeterFalk flick ''Film/TheBloodyBrood'', Falk plays a psychotic beatnik who feeds some poor kid a hamburger filled with broken glass to watch him die... [[ForTheEvulz just for kicks]].
* One of the final revelations Detective Ma receives in ''Film/BloodyReunion'' is that the victims of the massacre [[spoiler:had all been poisoned before their bodies were mutilated]]. When he returns to the scene of the crime, he discovers that [[spoiler:the cake Mi-Ja served everyone]] had been poisoned.
* In ''Film/TheBody2012'', Álex spikes his wife Mayka's wine with TH-16: a cardie-toxin that causes a cardiac arrest 8 hours after ingestion. [[spoiler:He later learns that Carla/Eva spiked his own drink with TH-16 just before he left for the morgue: almost 8 hours earlier.]]
* In ''Film/CasinoRoyale2006'', Film/JamesBond gets an absolutely fatal dose of digitalis in his drink. It's subverted with the defibrillator/first aid kit in his car, and ''that'' in turn is subverted when he doesn't have it connected properly. Vesper Lynd's arrival is just dumb luck.
* The massacre of adults of Gatlin in ''Film/ChildrenOfTheCorn1984'' starts when some diner patrons start choking from their poisoned coffee.
* Downplayed and subverted in ''Film/ChildrensPartyAtThePalace''. The Grand High Witch planned to put her potion in the [[UsefulNotes/HMTheQueen Queen]]'s cake that would [[ForcedTransformation turn whoever eats from it into mice]], until she finds out there was no cake to begin with. Eventually the villains bake their own cake with her potion in it...but turns out the potion had no effect on the Goodies.
* ''Film/TheCourtJester'' combines this with PoisonedChaliceSwitcheroo.
-->The pellet with the poison's in the vessel with the pestle, the chalice from the palace has the brew that is true.\\
No! The Flagon with the Dragon holds the pellet with the poison, the vessel with the pestle has the brew that is true.
* In ''Film/TheCrimeDoctorsStrangestCase'', the bedbound Walter Burns is murdered by someone poisoning his coffee.
* In ''Film/CrookedHouse'', the murderer doses Josephine's hot chocolate with cyanide, although Josephine is not the one who ends up drinking it.
* In ''Film/DeadAgainInTombstone'', Zerelda attempts to dispose of Boomer by lacing his eggs with cyanide.
* The Axis powers in ''Film/FDRAmericanBadass'' attempt to covertly attack US by smuggling in tainted alcohol that can turn anyone consuming it to a werewolf.
* ''Film/TheFourMusketeers'' (1974). D'Artagnan receives a case of wine along with a note that indicates it's from his fellow Musketeers. Before he can drink any of it, an enemy {{mook|s}} drinks some and dies; it was poisoned wine sent by Milady to kill him.
* In ''Film/TheGentlemen'', Mickey has Lord George's tea poisoned, then leaves him with the antidote, the point having been to demonstrate that he could get to Lord George anywhere.
* In ''Film/GhostShip'' there's a flashback comprised of a montage of images of what occurred on the ocean liner. During this, there's a scene in the kitchen where cooks are putting rat poison in food. We then see passengers eating the food and one person vomits as a result.
* In ''Film/GoodBurger'', after many failed attempts at getting Ed to spill the beans of the secret recipe of his homemade sauce (which put Good Burger in business over Mondo Burger), Kurt, owner of the latter restaurant, and his employees lock up Ed and Dexter in the asylum and break into Good Burger, in which they douse the sauce with shark poison, hoping whoever devours some will file a lawsuit against Good Burger to put it out of business for good. Luckily, Dexter and Ed make it in time to break the news to the other employees before a single customer is able to eat a drop of the sauce.
* Done twice in Disney's ''Film/TheHauntedMansion'' with poison being put into goblets of wine.
* In ''Film/HesOutThere'', Maddy eats a poisoned cupcake that she finds in the woods, planted by the killer.
* In ''Film/AJollyBadFellow'', Bowles-Otterly poisons his first two victims by by slipping the poison into their drinks: giving Dr. Brass a glass of laced claret, and dosing Mrs Pugh-Smith's gin-spiked water.
* In ''Film/{{Kate}}'' the title character is a professional killer who discovers she has been poisoned with Polonium-204, giving her accute radiation poisoning. She quickly realises the culprit was a man she picked up for a one-night stand, though he'd been told by his employers he was SlippingAMickey instead.
* In ''Film/KillBill Vol. 2'', Elle Driver reveals that [[spoiler:she murdered Pai Mei by poisoning his fish heads]].
* ''Film/KindHeartsAndCoronets'': Unlike the more elaborate murders he concocts for his other targets, Louis disposes of the Reverend Lord Henry d'Ascoyne through the simple expedient of poisoning his wine.
* ''Film/KullTheConqueror'': Subverted. Kull and his friends board the ship of Juba, one of Kull's old associates from his days as a pirate, to travel to an island that contains the one weapon that can destroy the villainess. Juba serves them food and wine, which Kull suspects to be poisoned and only partakes after Juba drinks and eats from it himself. It turns out that the food wasn't poisoned, but it ''was'' [[SlippingAMickey drugged]]. Juba's men tie up Kull and his team while their boss is unconscious.
* Parodied and averted in ''Film/LemonadeJoe'', a relentless parody of TheWestern. Hogo Fogo has kidnapped [[DamselInDistress Winnifred]] and plans to subject her to a fate worse than death, but is eating dinner in the saloon first. His brother, the less evil saloon owner, says he thinks Hogo's disgusting. Hogo opens his ring, puts some powder into a glass of water, and mixes it in. It looks like he'll try to make his brother drink it; [[spoiler:however, he then drinks it himself, and burps. It was antacid. He keeps eating his dinner, glutton that he is.]]
* In ''Film/TheManWithNineLives'', Dr. Kravaal drugs the soup Judy serves the thawed {{Human Popsicle}}s to knock them out so he can use them as guinea pigs for his experiments.
* In ''Film/{{MFA}}'', Noelle spikes the drink of one of the frat boy rapists with a date rape drug, then holds him down so he chokes on his own vomit.
* ''Film/MrsDoubtfire'': Daniel Hillard spikes his ex-wife's new paramour's meal with pepper after overhearing him stress to the waiter to ''not'' put pepper on it, as he's allergic. Even though the whole sequence is PlayedForLaughs, they came pretty close to the possibly fatal consequences of such a prank -- upon tasting the pepper, the man almost immediately begins choking, prompting Daniel to say, "Oh no, I killed the bastard!"
* In ''Film/MurderAtTheBaskervilles'', Hunter is murdered when powdered opium is slipped into his curried lamb.
* ''Film/MurderByDeath'': Lionel Twain arranges for one of the cups of wine served to the guests to have a tasteless, odorless [[PoisonIsCorrosive acidic poison]] in it. It turns out to be a subversion: Twain made sure the cup with the poisoned wine was served to the one guest who could identify it.
* The horror movie ''Film/NightOfTheDemons1988'' features a mean old man who puts razor blades in apples on Halloween to do [[MoralEventHorizon terrible things to children]]. At the end of the movie, [[spoiler:his wife makes an apple pie out of the leftover apples, which he eats. [[HoistByHisOwnPetard The blades slash through his throat and leave him dead.]]]]
* In ''Film/RaidersOfTheLostArk'', an Arab working for the Nazis pours poison on dates in Sallah's house in the hope that Sallah and/or Indy will eat them. The monkey steals the poisoned dates instead.
* In ''Film/RehearsalForMurder'', Karen and Leo's motive revolves around them supposedly giving Monica a herbal tea to "calm her nerves", which was actually spiked to make her too sick to perform on opening night.
* In ''Film/Sahara2005'', we have a rare version where the perpetrator is one of the good guys; [[spoiler:Jim Sandecker gives multiple requests before he decides to do any more work for the US government, but we don't hear him say the last one; the next scene is Massarde being poisoned in a restaurant by Jim's ally, Carl.]]
* Creator/GuyRitchie's ''Franchise/SherlockHolmes'' duology:
** Being aware of this doesn't prevent it, as seen in ''Film/SherlockHolmes2009''. Irene Adler pulls a clever one on Holmes in using an ''unopened'' bottle of wine. A flashback reveals she used a syringe to inject a knockout drug through the cork, and a match to re-melt the wax and conceal the hole.
** At the beginning of the [[Film/SherlockHolmesAGameOfShadows next movie]], Irene is smart enough to ask for a fresh pot of tea when meeting with Professor Moriarty, rather than drinking from the one already on the table. [[spoiler:Unfortunately Moriarty has bought out the entire restaurant. All the potential witnesses get up and leave at his signal, and the new pot turns out to be poisoned. Cue SoundOnlyDeath.]]
* In ''Film/TheSixthSense'' one of the [[ItWasHisSled dead people the kid sees]] is a small girl who was poisoned by her mother putting cleaning fluid in her soup.
* ''Film/SympathyForLadyVengeance'': In prison, Geum-ja kills the Witch by adulterating her food with bleach. ''For three years!''
* Creator/JohnCarpenter's ''Film/TheThing1982'' has the characters being ProperlyParanoid about this -- one single cell could be enough to turn anyone into a Thing. "I think everyone had better prepare their own food from now on..."
* In ''Film/ThirteenWomen'', Ursula attempts to murder Laura's son Bobby by sending him a box of poisoned chocolates.
* ''Film/WeddingCrashers'': At dinner in one scene, John proceeds to spike Zach's water with eye-drops, which makes him sick, thereby letting John connect with Claire, Zach's fiance.
* In Film/TheThreeStooges short "[[Recap/TheThreeStoogesWhoDoneIt Who Done It?]]", the villainess prepares two drinks and slips poison in Shemp's drink. The two distract each other while they [[PoisonedChaliceSwitcheroo switch the goblets]]. Finally, Shemp drinks down the poison and goes through some hysterical death throes. Naturally, he recovers.
* ''Film/WildTales'': In ''Las Ratas'', the waitress refuses the cook's offer to put rat poison in Cuenca's food, but the cook poisons it anyway.
* ''Film/WildThings'': Double subverted. When after all the backstabbing between the conspirators only a final guy and girl are left, the guy is smart enough to expect the drink he's offered to be poisoned but is assured when the girl tells him that she would be an idiot to try it because he's the only one who can pilot the sailboat they're on back to shore. This is a lie--the drink is indeed poisoned, and the girl is much smarter than she made herself out to be. Just to be sure, she releases one of the booms to knock him into the water to drown.
* In ''Film/TheWitchFiles'', [[spoiler:Jules]] gives MJ a green smoothie laced with ergot. MJ, having been forewarned, tosses it in the bin as soon as she is out of sight.
* ''Film/TheWrestler'':
** [[spoiler:Jules]] gives MJ a green smoothie laced with ergot. MJ, having been forewarned, tosses it in the bin as soon as she is out of sight.
** Randy, in his day job at the deli counter of a local grocery store, encounters a particularly indecisive elderly lady who keeps asking for "a little more" or "a little less" potato salad. Annoyed at her, he discreetly licks a few dips of his gloved fingers as he's disposing of excess. He later on proceeds to cut some meat and intentionally slice his fingers open and bleed on everyone in a ScrewThisImOuttaHere move.
* This is Graham's standard M.O. in ''Film/TheYoungPoisonersHandbook'': poisoning food and drink. Tea is his most common medium, but he also uses sandwiches, chocolates, pickles, beer, etc.
----
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%% This page has been alphabetized. Please add new examples in the correct order. Thanks!
%%
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TamperingWithFoodAndDrink in LiveActionFilms.
----
* ''Film/TwelveHourShift'': Nurse Mandy offers coffee to the security guard watching over the hospitalized inmate, failing to mention she added morphine.
* Spoofed in ''Film/TheAddamsFamily'': Fester brought some cyanide with him when he moved in, with the implication that he'd poison the family this way. When Morticia finds it, she just smiles and asks if he thought they'd run out of it. The implication is the family uses cyanide as ''seasoning''.
* In ''Film/{{Andhadhun}}'', Simi pours poison into Akash's tea in front of his eyes ([[ObfuscatingDisability he's pretending to be blind]]). [[spoiler:After he "accidentally" spills the tea, he finds out that a sweet he ate earlier was also poisoned.]]
* In ''Film/TheAssassinationBureau'', Eleanora first poisons [[spoiler:her husband Cesare, the Italian assassin]], then prepares drinks for herself and Dragomiloff, slipping poison in his drink. Dragomiloff spins the table until it stops, picks up the goblet in front of him, drinks down the contents, and falls to the floor. [[spoiler:He was faking it.]]
* In ''Film/BattleRoyale'', Yuko Sakaki puts potassium cyanide in spaghetti that Yukie Utsumi's friends cooked for Shuya Nanahara. Yuko then tries to deliver the spaghetti to Shuya personally, but Yuka Nakagawa snatches it away and eats it. [[spoiler:She then suffers from the poisoning, vomits much of her blood out of her mouth, then quickly dies. This results in Haruka, Yukie, Chisato (but ironically, not Yuko) all getting shot by Satomi out of suspicion she can't trust any of the girls.]]
* Johnny from ''Film/TheBigCube'' slips LSD into people's drinks at parties. He's kicked out of medical school after one of his victims runs into traffic and dies. Later, he and Lisa hide LSD inside Adriana's anxiety pills.
* In ''Film/BlindDate'', [[Creator/BruceWillis Walter]] uses a tiny syringe to put alcohol in chocolates he has delivered to Nadia because she has an extreme allergic reaction to alcohol.
* In the early Creator/PeterFalk flick ''Film/TheBloodyBrood'', Falk plays a psychotic beatnik who feeds some poor kid a hamburger filled with broken glass to watch him die... [[ForTheEvulz just for kicks]].
* One of the final revelations Detective Ma receives in ''Film/BloodyReunion'' is that the victims of the massacre [[spoiler:had all been poisoned before their bodies were mutilated]]. When he returns to the scene of the crime, he discovers that [[spoiler:the cake Mi-Ja served everyone]] had been poisoned.
* In ''Film/TheBody2012'', Álex spikes his wife Mayka's wine with TH-16: a cardie-toxin that causes a cardiac arrest 8 hours after ingestion. [[spoiler:He later learns that Carla/Eva spiked his own drink with TH-16 just before he left for the morgue: almost 8 hours earlier.]]
* In ''Film/CasinoRoyale2006'', Film/JamesBond gets an absolutely fatal dose of digitalis in his drink. It's subverted with the defibrillator/first aid kit in his car, and ''that'' in turn is subverted when he doesn't have it connected properly. Vesper Lynd's arrival is just dumb luck.
* The massacre of adults of Gatlin in ''Film/ChildrenOfTheCorn1984'' starts when some diner patrons start choking from their poisoned coffee.
* Downplayed and subverted in ''Film/ChildrensPartyAtThePalace''. The Grand High Witch planned to put her potion in the [[UsefulNotes/HMTheQueen Queen]]'s cake that would [[ForcedTransformation turn whoever eats from it into mice]], until she finds out there was no cake to begin with. Eventually the villains bake their own cake with her potion in it...but turns out the potion had no effect on the Goodies.
* ''Film/TheCourtJester'' combines this with PoisonedChaliceSwitcheroo.
-->The pellet with the poison's in the vessel with the pestle, the chalice from the palace has the brew that is true.\\
No! The Flagon with the Dragon holds the pellet with the poison, the vessel with the pestle has the brew that is true.
* In ''Film/TheCrimeDoctorsStrangestCase'', the bedbound Walter Burns is murdered by someone poisoning his coffee.
* In ''Film/CrookedHouse'', the murderer doses Josephine's hot chocolate with cyanide, although Josephine is not the one who ends up drinking it.
* In ''Film/DeadAgainInTombstone'', Zerelda attempts to dispose of Boomer by lacing his eggs with cyanide.
* The Axis powers in ''Film/FDRAmericanBadass'' attempt to covertly attack US by smuggling in tainted alcohol that can turn anyone consuming it to a werewolf.
* ''Film/TheFourMusketeers'' (1974). D'Artagnan receives a case of wine along with a note that indicates it's from his fellow Musketeers. Before he can drink any of it, an enemy {{mook|s}} drinks some and dies; it was poisoned wine sent by Milady to kill him.
* In ''Film/TheGentlemen'', Mickey has Lord George's tea poisoned, then leaves him with the antidote, the point having been to demonstrate that he could get to Lord George anywhere.
* In ''Film/GhostShip'' there's a flashback comprised of a montage of images of what occurred on the ocean liner. During this, there's a scene in the kitchen where cooks are putting rat poison in food. We then see passengers eating the food and one person vomits as a result.
* In ''Film/GoodBurger'', after many failed attempts at getting Ed to spill the beans of the secret recipe of his homemade sauce (which put Good Burger in business over Mondo Burger), Kurt, owner of the latter restaurant, and his employees lock up Ed and Dexter in the asylum and break into Good Burger, in which they douse the sauce with shark poison, hoping whoever devours some will file a lawsuit against Good Burger to put it out of business for good. Luckily, Dexter and Ed make it in time to break the news to the other employees before a single customer is able to eat a drop of the sauce.
* Done twice in Disney's ''Film/TheHauntedMansion'' with poison being put into goblets of wine.
* In ''Film/HesOutThere'', Maddy eats a poisoned cupcake that she finds in the woods, planted by the killer.
* In ''Film/AJollyBadFellow'', Bowles-Otterly poisons his first two victims by by slipping the poison into their drinks: giving Dr. Brass a glass of laced claret, and dosing Mrs Pugh-Smith's gin-spiked water.
* In ''Film/{{Kate}}'' the title character is a professional killer who discovers she has been poisoned with Polonium-204, giving her accute radiation poisoning. She quickly realises the culprit was a man she picked up for a one-night stand, though he'd been told by his employers he was SlippingAMickey instead.
* In ''Film/KillBill Vol. 2'', Elle Driver reveals that [[spoiler:she murdered Pai Mei by poisoning his fish heads]].
* ''Film/KindHeartsAndCoronets'': Unlike the more elaborate murders he concocts for his other targets, Louis disposes of the Reverend Lord Henry d'Ascoyne through the simple expedient of poisoning his wine.
* ''Film/KullTheConqueror'': Subverted. Kull and his friends board the ship of Juba, one of Kull's old associates from his days as a pirate, to travel to an island that contains the one weapon that can destroy the villainess. Juba serves them food and wine, which Kull suspects to be poisoned and only partakes after Juba drinks and eats from it himself. It turns out that the food wasn't poisoned, but it ''was'' [[SlippingAMickey drugged]]. Juba's men tie up Kull and his team while their boss is unconscious.
* Parodied and averted in ''Film/LemonadeJoe'', a relentless parody of TheWestern. Hogo Fogo has kidnapped [[DamselInDistress Winnifred]] and plans to subject her to a fate worse than death, but is eating dinner in the saloon first. His brother, the less evil saloon owner, says he thinks Hogo's disgusting. Hogo opens his ring, puts some powder into a glass of water, and mixes it in. It looks like he'll try to make his brother drink it; [[spoiler:however, he then drinks it himself, and burps. It was antacid. He keeps eating his dinner, glutton that he is.]]
* In ''Film/TheManWithNineLives'', Dr. Kravaal drugs the soup Judy serves the thawed {{Human Popsicle}}s to knock them out so he can use them as guinea pigs for his experiments.
* In ''Film/{{MFA}}'', Noelle spikes the drink of one of the frat boy rapists with a date rape drug, then holds him down so he chokes on his own vomit.
* ''Film/MrsDoubtfire'': Daniel Hillard spikes his ex-wife's new paramour's meal with pepper after overhearing him stress to the waiter to ''not'' put pepper on it, as he's allergic. Even though the whole sequence is PlayedForLaughs, they came pretty close to the possibly fatal consequences of such a prank -- upon tasting the pepper, the man almost immediately begins choking, prompting Daniel to say, "Oh no, I killed the bastard!"
* In ''Film/MurderAtTheBaskervilles'', Hunter is murdered when powdered opium is slipped into his curried lamb.
* ''Film/MurderByDeath'': Lionel Twain arranges for one of the cups of wine served to the guests to have a tasteless, odorless [[PoisonIsCorrosive acidic poison]] in it. It turns out to be a subversion: Twain made sure the cup with the poisoned wine was served to the one guest who could identify it.
* The horror movie ''Film/NightOfTheDemons1988'' features a mean old man who puts razor blades in apples on Halloween to do [[MoralEventHorizon terrible things to children]]. At the end of the movie, [[spoiler:his wife makes an apple pie out of the leftover apples, which he eats. [[HoistByHisOwnPetard The blades slash through his throat and leave him dead.]]]]
* In ''Film/RaidersOfTheLostArk'', an Arab working for the Nazis pours poison on dates in Sallah's house in the hope that Sallah and/or Indy will eat them. The monkey steals the poisoned dates instead.
* In ''Film/RehearsalForMurder'', Karen and Leo's motive revolves around them supposedly giving Monica a herbal tea to "calm her nerves", which was actually spiked to make her too sick to perform on opening night.
* In ''Film/Sahara2005'', we have a rare version where the perpetrator is one of the good guys; [[spoiler:Jim Sandecker gives multiple requests before he decides to do any more work for the US government, but we don't hear him say the last one; the next scene is Massarde being poisoned in a restaurant by Jim's ally, Carl.]]
* Creator/GuyRitchie's ''Franchise/SherlockHolmes'' duology:
** Being aware of this doesn't prevent it, as seen in ''Film/SherlockHolmes2009''. Irene Adler pulls a clever one on Holmes in using an ''unopened'' bottle of wine. A flashback reveals she used a syringe to inject a knockout drug through the cork, and a match to re-melt the wax and conceal the hole.
** At the beginning of the [[Film/SherlockHolmesAGameOfShadows next movie]], Irene is smart enough to ask for a fresh pot of tea when meeting with Professor Moriarty, rather than drinking from the one already on the table. [[spoiler:Unfortunately Moriarty has bought out the entire restaurant. All the potential witnesses get up and leave at his signal, and the new pot turns out to be poisoned. Cue SoundOnlyDeath.]]
* In ''Film/TheSixthSense'' one of the [[ItWasHisSled dead people the kid sees]] is a small girl who was poisoned by her mother putting cleaning fluid in her soup.
* ''Film/SympathyForLadyVengeance'': In prison, Geum-ja kills the Witch by adulterating her food with bleach. ''For three years!''
* Creator/JohnCarpenter's ''Film/TheThing1982'' has the characters being ProperlyParanoid about this -- one single cell could be enough to turn anyone into a Thing. "I think everyone had better prepare their own food from now on..."
* In ''Film/ThirteenWomen'', Ursula attempts to murder Laura's son Bobby by sending him a box of poisoned chocolates.
* ''Film/WeddingCrashers'': At dinner in one scene, John proceeds to spike Zach's water with eye-drops, which makes him sick, thereby letting John connect with Claire, Zach's fiance.
* In Film/TheThreeStooges short "[[Recap/TheThreeStoogesWhoDoneIt Who Done It?]]", the villainess prepares two drinks and slips poison in Shemp's drink. The two distract each other while they [[PoisonedChaliceSwitcheroo switch the goblets]]. Finally, Shemp drinks down the poison and goes through some hysterical death throes. Naturally, he recovers.
* ''Film/WildTales'': In ''Las Ratas'', the waitress refuses the cook's offer to put rat poison in Cuenca's food, but the cook poisons it anyway.
* ''Film/WildThings'': Double subverted. When after all the backstabbing between the conspirators only a final guy and girl are left, the guy is smart enough to expect the drink he's offered to be poisoned but is assured when the girl tells him that she would be an idiot to try it because he's the only one who can pilot the sailboat they're on back to shore. This is a lie--the drink is indeed poisoned, and the girl is much smarter than she made herself out to be. Just to be sure, she releases one of the booms to knock him into the water to drown.
* In ''Film/TheWitchFiles'', [[spoiler:Jules]] gives MJ a green smoothie laced with ergot. MJ, having been forewarned, tosses it in the bin as soon as she is out of sight.
* ''Film/TheWrestler'':
** [[spoiler:Jules]] gives MJ a green smoothie laced with ergot. MJ, having been forewarned, tosses it in the bin as soon as she is out of sight.
** Randy, in his day job at the deli counter of a local grocery store, encounters a particularly indecisive elderly lady who keeps asking for "a little more" or "a little less" potato salad. Annoyed at her, he discreetly licks a few dips of his gloved fingers as he's disposing of excess. He later on proceeds to cut some meat and intentionally slice his fingers open and bleed on everyone in a ScrewThisImOuttaHere move.
* This is Graham's standard M.O. in ''Film/TheYoungPoisonersHandbook'': poisoning food and drink. Tea is his most common medium, but he also uses sandwiches, chocolates, pickles, beer, etc.
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