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* Iggy from ''ComicStrip/DogsOfCKennel''.

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* Iggy from ''ComicStrip/DogsOfCKennel''.''ComicStrip/DogsOfCKennel'' is a hypochondriac who imagines he has all kinds of conditions, such as brain hemorrhages ([[https://www.gocomics.com/dogsofckennel/2010/10/18 as in this strip]]), as well as being paranoid about contracting disease-causing microbes ([[https://www.gocomics.com/dogsofckennel/2010/11/21 as in this comic]], where it's implied he thinks he has caught Ebola). In yet [[https://www.gocomics.com/dogsofckennel/2011/02/23 another strip]], he is seen sterilizing his water dish after Kenny drank from it--with a flame thrower!



* Spotless [=McPartland=], in Dick Cavalli's ''ComicStrip/{{Winthrop}}''.

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* %%* Spotless [=McPartland=], in Dick Cavalli's ''ComicStrip/{{Winthrop}}''.%%%ZCE-needs expanding



* ''Series/{{The Boys|2019}}'': Annie notes in season 2 that Mother's Milk suffers from OCD (Obsessive-Compulsive Disorder). [[spoiler:Season 3 reveals that these tics are a result of the trauma he sustained from seeing his grandfather get killed by Soldier Boy.]]



* ''Series/TheRegime'': Chancellor Elena Vernham, is terrified of mold because she inherited the same illness (AAT deficiency) that led her father to develop lung disease. Everybody around her enables her paranoia; in the first episode, she can be seen sitting surrounded by four industrial-size dehumidifiers. She is even more paranoid about this obsession being known to the public, as it makes her look weak. This fear is exploited in episode 6 when [[spoiler: a former member of her Cabinet tortures her into cooperating by strapping her into an oxygen mask attached to a tank labeled "Danger, Black Mould."]]



* ''Series/{{The Boys|2019}}'': Annie notes in season 2 that Mother's Milk suffers from OCD (Obsessive-Compulsive Disorder). [[spoiler:Season 3 reveals that these tics are a result of the trauma he sustained from seeing his grandfather get killed by Soldier Boy.]]
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[[caption-width-right:248:For context, he's in a ''sewer tunnel''. And he soon runs out of wipes...]]
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* ''Series/{{The Boys|2019}}'': Mother's Milk suffers from OCD (Obsessive-Compulsive Disorder).

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* ''Series/{{The Boys|2019}}'': Annie notes in season 2 that Mother's Milk suffers from OCD (Obsessive-Compulsive Disorder).Disorder). [[spoiler:Season 3 reveals that these tics are a result of the trauma he sustained from seeing his grandfather get killed by Soldier Boy.]]
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* ''Series/{{Monk}}'''s eponymous character, Adrian Monk, to the extent that he uses wipes every time he shakes hands with someone, and gets highly distressed (well, more than usual, anyway) if somehow prevented from doing so.

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* ''Series/{{Monk}}'''s eponymous character, Adrian Monk, ''Series/{{Monk}}'': The titular character is a germaphobe to the extent that he uses wipes every time he shakes hands with someone, and gets highly distressed (well, more than usual, anyway) if somehow prevented from doing so.



* Howie Mandel. This is why he never shakes hands-on ''Series/DealOrNoDeal'' or ''Series/AmericasGotTalent'' and is apparently the reason he shaves his head.

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* Howie Mandel. Creator/HowieMandel. This is why he never shakes hands-on does fist bumps instead of handshakes on ''Series/DealOrNoDeal'' or ''Series/AmericasGotTalent'' ''Series/AmericasGotTalent'', and is apparently the reason he shaves his head.
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* The appropriately-named henchman "Germs" in the ''WesternAnimation/BatmanTheAnimatedSeries'' two-parter "[[Recap/BatmanTheAnimatedSeriesE20FeatOfClayPart1 Feat of Clay: Part 1]]/[[Recap/BatmanTheAnimatedSeriesE21FeatOfClayPart2 Part 2]]". He opens doors using a handkerchief and is visibly squicked at going to a hospital. Batman [[FlawExploitation exploits this]] entertainingly when interrogating him, threatening him with a jar he claims contains an incurable disease. Clayface leaves him practically catatonic after binding and ''gagging'' the little creep with some of his clay body.

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* The appropriately-named henchman "Germs" in the ''WesternAnimation/BatmanTheAnimatedSeries'' two-parter "[[Recap/BatmanTheAnimatedSeriesE20FeatOfClayPart1 Feat of Clay: Part 1]]/[[Recap/BatmanTheAnimatedSeriesE21FeatOfClayPart2 Part 2]]". He opens doors using a handkerchief and is visibly squicked at going to a hospital. Batman [[FlawExploitation exploits this]] entertainingly when interrogating him, threatening him with a jar he claims contains an incurable disease.disease (actually ordinary seawater). Clayface leaves him practically catatonic after binding and ''gagging'' the little creep with some of his clay body.
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[[folder:Web Original]]
* Script/SeinfeldTheTwinTowers: Jerry becomes paranoid about running into any remaining dust from the Twin Towers collapsing, not the least because it could contain people's pulverized remains. He gets to the point where he wears gloves and a mask whenever he goes outside and has a panic attack whenever he sees dust of any kind.
[[/folder]]
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Known to psychologists as "mysophobia"[[note]]This fear specifically covers the fear of dirt, pathogens and contamination, but is often simplified in popular culture to just the fear of germs[[/note]] and to others as "germophobia", this trope describes characters who have a crippling fear of germs. This is one of the common symptoms of UsefulNotes/ObsessiveCompulsiveDisorder and a phobia that, in fact, more or less affects most people. We are instinctively afraid of all things that are by definition highly contagious (like rotting corpses or waste), and for a good reason; this trope is about someone who lets this fear consume them.

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Known to psychologists as "mysophobia"[[note]]This mysophobia[[note]]This fear specifically covers the fear of dirt, pathogens and contamination, but is often simplified in popular culture to just the fear of germs[[/note]] and to others as "germophobia", germophobia, this trope describes characters who have a crippling fear of germs. This is one of the common symptoms of UsefulNotes/ObsessiveCompulsiveDisorder and a phobia that, in fact, more or less affects most people. We are instinctively afraid of all things that are by definition highly contagious (like rotting corpses or waste), and for a good reason; this trope is about someone who lets this fear consume them.
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Known to psychologists as "mysophobia" and to others as "germophobia", this trope describes characters who have a crippling fear of germs. This is one of the common symptoms of UsefulNotes/ObsessiveCompulsiveDisorder and a phobia that, in fact, more or less affects most people. We are instinctively afraid of all things that are by definition highly contagious (like rotting corpses or waste), and for a good reason; this trope is about someone who lets this fear consume them.

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Known to psychologists as "mysophobia" "mysophobia"[[note]]This fear specifically covers the fear of dirt, pathogens and contamination, but is often simplified in popular culture to just the fear of germs[[/note]] and to others as "germophobia", this trope describes characters who have a crippling fear of germs. This is one of the common symptoms of UsefulNotes/ObsessiveCompulsiveDisorder and a phobia that, in fact, more or less affects most people. We are instinctively afraid of all things that are by definition highly contagious (like rotting corpses or waste), and for a good reason; this trope is about someone who lets this fear consume them.
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Crosswicking from character page


* Dave from ''WesternAnimation/TotalDrama.''

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* Dave from ''WesternAnimation/TotalDrama.'''' His contestant bio states that he has mysophobia and he is seen rubbing his hands with disinfectant in his audition video. He gets nervous whenever a challenge involves getting dirty, and freaks out when he's covered in pig grease in "I Love You, Greased Pig!". In "This is the Pits!" he is seen in the fetal position after his team escape the underground tunnels by climbing out through the ''outhouse confessional'', covered in wastewater.
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* ''Series/TheBoys'': Mother's Milk suffers from OCD (Obsessive-Compulsive Disorder).

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* ''Series/TheBoys'': ''Series/{{The Boys|2019}}'': Mother's Milk suffers from OCD (Obsessive-Compulsive Disorder).
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* The appropriately-named henchman "Germs" in the ''WesternAnimation/BatmanTheAnimatedSeries'' two-parter "Feat of Clay". He opens doors using a handkerchief and is visibly squicked at going to a hospital. Batman [[FlawExploitation exploits this]] entertainingly when interrogating him, threatening him with a jar he claims contains an incurable disease. Clayface leaves him practically catatonic after binding and ''gagging'' the little creep with some of his clay body.

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* The appropriately-named henchman "Germs" in the ''WesternAnimation/BatmanTheAnimatedSeries'' two-parter "Feat "[[Recap/BatmanTheAnimatedSeriesE20FeatOfClayPart1 Feat of Clay".Clay: Part 1]]/[[Recap/BatmanTheAnimatedSeriesE21FeatOfClayPart2 Part 2]]". He opens doors using a handkerchief and is visibly squicked at going to a hospital. Batman [[FlawExploitation exploits this]] entertainingly when interrogating him, threatening him with a jar he claims contains an incurable disease. Clayface leaves him practically catatonic after binding and ''gagging'' the little creep with some of his clay body.
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* In ''Film/BedtimeStories2008'', hotel billionaire Barry Nottingham is [[ReasonableAuthorityFigure a perfectly nice, friendly authority figure]], but is utterly terrified of germs, to the point where when Skeeter needs to talk with him in his hotel suite, Nottingham insists they converse in near-total darkness simply because germs produce 80% faster in light. [[spoiler:By the end of the film, Skeeter manages to help him out of it, to the point where in the WhereAreTheyNowEpilogue, Nottingham [[{{Irony}} had decided to go to medical school and became a school nurse.]]]]

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* In ''Film/BedtimeStories2008'', hotel billionaire Barry Nottingham is [[ReasonableAuthorityFigure a perfectly nice, friendly authority figure]], but is utterly terrified of germs, which proves to the be an obstacle in several interactions. At one point where when Skeeter needs to talk with him in his hotel suite, Nottingham insists they converse in near-total darkness simply because germs produce 80% faster in light. [[spoiler:By the end of the film, Skeeter manages to help him out of it, to the point where in the WhereAreTheyNowEpilogue, Nottingham [[{{Irony}} had decided to go to medical school and became a school nurse.]]]]
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** In its sequel, ''The Naked Sun'', an Earthman visits Solaria, a Spacer world. They build him a house and he learns that they'll destroy it after he leaves the planet. However, it is stated that disease is not the matter here -- Solaria is considered fringe even by Spacer standards, and it is unthinkable for any of the planet's residents to tolerate another person in the same house.

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** In its sequel, ''The Naked Sun'', ''Literature/TheNakedSun'', an Earthman visits Solaria, a Spacer world. They build him a house and he learns that they'll destroy it after he leaves the planet. However, it is stated that disease is not the matter here -- Solaria is considered fringe even by Spacer standards, and it is unthinkable for any of the planet's residents to tolerate another person in the same house.
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* ''Series/TheBoys'': Mother's Milk suffers from OCD (Obsessive-Compulsive Disorder).
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* Becky, in ''Film/{{Ravers}}'', is terrified of germs. Notably, even in the midst of a deadly crisis, she is still hampered by her need to avoid source of potential infection, hampering her ability to escape.
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They're wriggling and raging like worms,\\

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They're wriggling and raging like worms,\\worms.\\

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