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** As a Side Effect of being the creator and controller of the Level Upper, Kiyama Harumi gains multi-skill, the ability to use the skills and powers of its users. Kihara Gensei later creates his own version.

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** As a Side Effect of being the creator and controller of the Level Upper, Kiyama Harumi gains multi-skill, the ability to use the skills and powers of its users. over 10,000 users.
**
Kihara Gensei later creates his own version.version and reveals gave Kiyama Harumi the idea. He doesn't posses the sheer quantity of Kiyama but makes up for it by choosing the abilities needed to reach Exterior.
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[[folder:Tabletop Games]]
* ''TabletopGame/BaseRaiders'': The disappearance of the world's superheroes and villains and subsequent looting of their secret bases has led to a wave of "DIY" superbeings who attempt to replicate the events that led someone to develop superpowers.
[[/folder]]
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What Urahara invented was a Dangerous Forbidden Technique that any shinigami can use to achieve their Bankai form. The catch is that it's a Die Or Fie technique, and most shinigami who attempt it end up dying. Bankai isn't a self-made power, however.


** TheChessmaster and OmnidisciplinaryScientist extraordinaire Kisuke Urahara invents a device called ''Tenshinta'' that allows him to achieve the final form of his sword within 3 days, something that takes a decade for even the most gifted Shinigami.
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Capitalization


** Dr. Wheelo from the movie ''Anime/DragonBallZTheWorldsStrongest'' is much like Dr.Gero, a brilliant scientist. HE transplanted his brain into a mecha. His goal is to take over Goku's body.

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** Dr. Wheelo from the movie ''Anime/DragonBallZTheWorldsStrongest'' is much like Dr.Gero, a brilliant scientist. HE He transplanted his brain into a mecha. His goal is to take over Goku's body.
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Plural


** Aizen Sosuke created the Hogyoku to break the limit of Shinigami potential and steals Kisuke Urahara's, the only person he acknowledges to be smarter than him, to create a single one. He gains so many transformations and powers that it is best to see his page.

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** Aizen Sosuke created the Hogyoku to break the limit limits of Shinigami potential and steals Kisuke Urahara's, the only person he acknowledges to be smarter than him, to create a single one. He gains so many transformations and powers that it is best to see his page.
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Grammar


* Giovanni of ''Manga/FireForce'' modified his body can transform into countless firebugs, gaining insect-like traits to increase his strength even further. Even when decapitated, he still survives as his head can move according to his thoughts.

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* Giovanni of ''Manga/FireForce'' modified his body can to be able to transform into countless firebugs, gaining insect-like traits to increase his strength even further. Even when decapitated, he still survives as his head can move according to his thoughts.
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* In the third season premiere of ''Series/{{Heroes}}'', Mohinder Suresh takes a syringe of Maya's blood/DNA/super-powered-{{Phlebotinum}} out onto a dock all by himself and injects it into himself, becoming a case of ProfessorGuineaPig; He gets insect-like super-strength, agility, and wall-climbing ability, but as a side effect appears to be mutating uncontrollably. Once the perfected formula he develops washes over him, he gains superhuman strength.

to:

* In the third season premiere of ''Series/{{Heroes}}'', Mohinder Suresh takes a syringe of Maya's blood/DNA/super-powered-{{Phlebotinum}} out onto a dock all by himself and injects it into himself, becoming a case of ProfessorGuineaPig; He gets insect-like super-strength, agility, and wall-climbing ability, and coocon generation, but as a side effect appears to be mutating uncontrollably. Once the perfected formula he develops washes over him, he gains superhuman strength.
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** Orochimaru, the BigBad of Part I and a brilliant scientist, [[BioAugmentation modified his body]] to be very [[VoluntaryShapeshifting malleable]] and snakelike, a power he refers to as the Power of the White Snake. He gains a HealingFactor, ability to reconnect body parts via snakes, shed his skin to regurgitate a new body free from all damage, etc. Most importantly, he gains the power to use Living Corpse Reincarnation, his path to immortality that allows him to [[GrandTheftMe transfer his consciousness to another body]]. He can store his consciousness within the cursed seals he brands others with, allowing him to revive himself even after being sealed by Itachi Uchiha's extremely powerful sealing jutsu.

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** Orochimaru, the BigBad of Part I and a brilliant scientist, [[BioAugmentation modified his body]] to be very [[VoluntaryShapeshifting malleable]] and snakelike, a power he refers to as the Power of the White Snake. He gains a HealingFactor, ability to reconnect body parts via snakes, shed his skin to regurgitate a new body free from all damage, etc. Most importantly, he gains the power to use Living Corpse Reincarnation, his path to immortality that allows him to [[GrandTheftMe transfer his consciousness to another body]]. He can store his consciousness within the cursed seals he brands others with, allowing him to revive himself himself, albeit with some outside help, even after being sealed by Itachi Uchiha's extremely powerful sealing jutsu.
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No tropes in page quotes.


->''"Well, not every superhero has powers, you know. You can be super without them. I invented [[RocketBoots these]]. I can fly. Can you fly?"''

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->''"Well, not every superhero has powers, you know. You can be super without them. I invented [[RocketBoots these]].these. I can fly. Can you fly?"''
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->''"Well, not every superhero has powers, you know. You can be super without them. I invented these. I can fly. Can you fly?"''

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->''"Well, not every superhero has powers, you know. You can be super without them. I invented these.[[RocketBoots these]]. I can fly. Can you fly?"''
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->''"Well, not every superhero has powers, you know. You can be super without them. I invented these. I can fly. Can you fly?"''
-->-- '''Incredi-boy''' to '''Mr. Incredible''', ''WesternAnimation/TheIncredibles''

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** Obito Uchiha is a skilled surgeon and well-versed with genetics and transplants. He made up for his lack of natural talent by mastering Hashirama's cell, allowing him to phase through all attacks for 10 minutes with 1 Sharingan, and later transplants a Rinnegan stolen from Nagato's corpse.

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** Obito Uchiha is a skilled surgeon and well-versed with genetics and transplants. He made up for his lack of natural talent by mastering Hashirama's cell, cells, allowing him to phase through all attacks for 10 minutes with 1 Sharingan, and later transplants a Rinnegan stolen from Nagato's corpse.
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** Orochimaru, a brilliant scientist, [[BioAugmentation modified his body]] to be very [[VoluntaryShapeshifting malleable]] and snakelike, a power he refers to as the Power of the White Snake. He gains a HealingFactor, ability to reconnect body parts via snakes, shed his skin to regurgitate a new body free from all damage, etc. Most importantly, he gains the power to use Living Corpse Reincarnation, his path to immortality that allows him to [[GrandTheftMe transfer his consciousness to another body]]. He can store his consciousness within the cursed seals he brands others with, allowing him to revive himself even after being sealed by Itachi Uchiha's extremely powerful sealing jutsu.

to:

** Orochimaru, the BigBad of Part I and a brilliant scientist, [[BioAugmentation modified his body]] to be very [[VoluntaryShapeshifting malleable]] and snakelike, a power he refers to as the Power of the White Snake. He gains a HealingFactor, ability to reconnect body parts via snakes, shed his skin to regurgitate a new body free from all damage, etc. Most importantly, he gains the power to use Living Corpse Reincarnation, his path to immortality that allows him to [[GrandTheftMe transfer his consciousness to another body]]. He can store his consciousness within the cursed seals he brands others with, allowing him to revive himself even after being sealed by Itachi Uchiha's extremely powerful sealing jutsu.
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** Orochimaru's right-hand man and highly skilled spy and CombatMedic, Yakushi Kabuto, integrated multiple Kekkei Genkai (unique abilities) into himself, granting him among others, a powerful HealingFactor, ability to liquefy, create a clone, use a SuperMode indefinitely along with becoming a MasterOfIllusion capable of overcoming Itachi and Sauske Uchiha simultaneously.

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** Orochimaru's right-hand man and highly skilled spy and CombatMedic, Yakushi Kabuto, integrated multiple Kekkei Genkai (unique abilities) into himself, granting him among others, other powers, a powerful HealingFactor, ability to liquefy, create a clone, use a SuperMode indefinitely along with becoming a MasterOfIllusion capable of overcoming Itachi and Sauske Uchiha simultaneously.
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None


** Orochimaru, a brilliant scientist, [[BioAugmentation modified his body]] to be very [[VoluntaryShapeshifting malleable]] and snakelike, a power he refers to as the Power of the White Snake. He gains a HealingFactor, ability to reconnect body parts via snakes, shed his skin to regurgitate a new body free from all damage, etc. Most importantly, he gains the power to use Living Corpse Reincarnation, his path to immortality that allows him to [[GrandTheftMe transfer his consciousness to another body]]. He can store his consciousness within the cursed seals he brands others with, allowing him to revive himself even after being sealed by Itachi Uchiha' extremely powerful sealing jutsu.

to:

** Orochimaru, a brilliant scientist, [[BioAugmentation modified his body]] to be very [[VoluntaryShapeshifting malleable]] and snakelike, a power he refers to as the Power of the White Snake. He gains a HealingFactor, ability to reconnect body parts via snakes, shed his skin to regurgitate a new body free from all damage, etc. Most importantly, he gains the power to use Living Corpse Reincarnation, his path to immortality that allows him to [[GrandTheftMe transfer his consciousness to another body]]. He can store his consciousness within the cursed seals he brands others with, allowing him to revive himself even after being sealed by Itachi Uchiha' Uchiha's extremely powerful sealing jutsu.
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None


** Orochimaru, a brilliant scientist, [[BioAugmentation modified his body]] to be very [[VoluntaryShapeshifting malleable]] and snakelike, a power he refers to as the Power of the White Snake. He gains a HealingFactor, ability to reconnect body parts via snakes, shed his skin to regurgitate a new body free from all damage, etc. Most importantly, he gains the power to use Living Corpse Reincarnation, his path to immortality that allows him to [[GrandTheftMe transfer his consciousness to another body]].

to:

** Orochimaru, a brilliant scientist, [[BioAugmentation modified his body]] to be very [[VoluntaryShapeshifting malleable]] and snakelike, a power he refers to as the Power of the White Snake. He gains a HealingFactor, ability to reconnect body parts via snakes, shed his skin to regurgitate a new body free from all damage, etc. Most importantly, he gains the power to use Living Corpse Reincarnation, his path to immortality that allows him to [[GrandTheftMe transfer his consciousness to another body]]. He can store his consciousness within the cursed seals he brands others with, allowing him to revive himself even after being sealed by Itachi Uchiha' extremely powerful sealing jutsu.
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None


** Orochimaru, a brilliant scientist, [[BioAugmentation modified his body]] to be very [[VoluntaryShapeshifting malleable]] and snakelike, a power he refers to as the Power of the White Snake. He gains a HealingFactor, ability to reconnect body parts via snakes, shed his skin to regurgitate a new body free from all damage, etc. Most importantly, he gains the power to use Living Corpse Reincarnation, his path to immortality that allows him to [[GrandTheftMe transfer his consciousness to another body]]

to:

** Orochimaru, a brilliant scientist, [[BioAugmentation modified his body]] to be very [[VoluntaryShapeshifting malleable]] and snakelike, a power he refers to as the Power of the White Snake. He gains a HealingFactor, ability to reconnect body parts via snakes, shed his skin to regurgitate a new body free from all damage, etc. Most importantly, he gains the power to use Living Corpse Reincarnation, his path to immortality that allows him to [[GrandTheftMe transfer his consciousness to another body]]body]].
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The solution is simple. Use your incredibly advanced mind to give yourself powers. Do some self-BioAugmentation. Create a ritual because it's TimeToUnlockMoreTruePotential that only the ChosenOne is entitled to. Build a device to [[GeneticEngineeringIsTheNewNuke mutate your genes]] into that of the resident RealityWarper. Integrate the {{Magitek}} you have stolen to your brain. Develop a SuperSerum to give yourself TheGift and become an InstantExpert.

to:

The solution is simple. Use your incredibly advanced mind to give yourself powers. Do some self-BioAugmentation. Give yourself an ArtificialLimb or [[{{Cyborg}} more]]. Create a ritual because it's TimeToUnlockMoreTruePotential that only the ChosenOne is entitled to. Build a device to [[GeneticEngineeringIsTheNewNuke mutate your genes]] into that of the resident RealityWarper. Integrate the {{Magitek}} you have stolen to your brain. Develop a SuperSerum to give yourself TheGift and become an InstantExpert.
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None


** TheChessmaster and OmnidisciplinaryScientist extraordinaire Kisuke Urahara invents a device that allows him to achieve the final form of his sword within 3 days, something that takes a decade for even the most gifted Shinigami.

to:

** TheChessmaster and OmnidisciplinaryScientist extraordinaire Kisuke Urahara invents a device called ''Tenshinta'' that allows him to achieve the final form of his sword within 3 days, something that takes a decade for even the most gifted Shinigami.
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more info


** Orochimaru, a brilliant scientist, [[BioAugmentation modified his body]] to be very [[VoluntaryShapeshifting malleable]] and snakelike, letting him shed his skin to recover FromASingleCell.

to:

** Orochimaru, a brilliant scientist, [[BioAugmentation modified his body]] to be very [[VoluntaryShapeshifting malleable]] and snakelike, letting him a power he refers to as the Power of the White Snake. He gains a HealingFactor, ability to reconnect body parts via snakes, shed his skin to recover FromASingleCell. regurgitate a new body free from all damage, etc. Most importantly, he gains the power to use Living Corpse Reincarnation, his path to immortality that allows him to [[GrandTheftMe transfer his consciousness to another body]]
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* ''ComicBook/RenewYourVows'': The BigBad of the story captures every single powered individual he can find and uses his scientific prowess to absorb their abilities. They die after that.
* ''ComicBook/SpiderMan2099'': In the 2019 reboot, unlike the original, Miguel, who is an Alchemax geneticist, gives himself his spider abilities on his own accord. [[spoiler: That's because of the urging of the original Miguel and the death of his brother Gabriel]].
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** Orochimaru, a brilliant scientist, gives himself powerful BioAugmentation, making himself immortal, be able to shed his body like a snake, and strong enough to fight Naruto in 3 tails form, without his jutsu.

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** Orochimaru, a brilliant scientist, gives himself powerful BioAugmentation, making himself immortal, [[BioAugmentation modified his body]] to be able to very [[VoluntaryShapeshifting malleable]] and snakelike, letting him shed his body like a snake, and strong enough skin to fight Naruto in 3 tails form, without his jutsu.recover FromASingleCell.
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The key point is that the character does the upgrading to themselves by giving themselves innate superpowers by themselves and can do so safely.

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The key point is that the character does the upgrading to themselves by giving themselves innate superpowers by themselves and can do so safely. May involve some SelfSurgery.
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The solution is simple. Use your incredibly advanced mind to give yourself powers. Create a ritual because it's TimeToUnlockMoreTruePotential that only the ChosenOne is entitled to. Build a device to mutate your genes into that of the resident RealityWarper. Integrate the {{Magitek}} you have stolen to your brain. Develop a serum to give yourself TheGift and become an InstantExpert.

to:

The solution is simple. Use your incredibly advanced mind to give yourself powers. Do some self-BioAugmentation. Create a ritual because it's TimeToUnlockMoreTruePotential that only the ChosenOne is entitled to. Build a device to [[GeneticEngineeringIsTheNewNuke mutate your genes genes]] into that of the resident RealityWarper. Integrate the {{Magitek}} you have stolen to your brain. Develop a serum SuperSerum to give yourself TheGift and become an InstantExpert.InstantExpert.



Not to be confused with ProfessorGuineaPig, which is about testing inventions on themselves while these people know what they are doing.

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Not to be confused May overlap with ProfessorGuineaPig, which is about testing inventions on themselves while these people themselves; the characters in this trope may alternatively know what they are doing.
they're doing.
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Compare CharlesAtlasSuperpower, when vigorous training is used to gain superpowers.

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Compare CharlesAtlasSuperpower, when vigorous training is used to gain superpowers.
superpowers, and GadgeteerGenius, for creating superpowered devices.

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[[folder:Anime and Manga]]

to:

[[folder:Anime and & Manga]]



** Dr. Gero is so brilliant that he creates multiple cyborgs and Android more powerful than the second strongest being in the universe, Freeza and the strongest Super Saiyans '' without ever leaving the Earth'', a very remote and weak planet. He then converts himself into a cyborg.

to:

** Dr. Gero is so brilliant that he creates multiple cyborgs and Android more powerful than the second strongest being in the universe, Freeza and the strongest Super Saiyans '' without ''without ever leaving the Earth'', a very remote and weak planet. He then converts himself into a cyborg.



* ''LightNovel/ACertainMagicalIndex'':
** Level Six Shift was claimed by Kihara Gensei to used to give Aleister Crowley this, though it remains unknown whether it is true.
** As a Side Effect of being the creator and controller of the Level Upper, Kiyama Harumi gains multi-skill, the ability to use the skills and powers of its users. Kihara Gensei later creates his own version.
** Becoming a Magic God involves "mastering a path to the very end" and becoming a nigh-omnipotent RealityWarper.



[[folder: Comic Book]]

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[[folder: Comic Book]][[folder:Comic Books]]



* ''ComicBook/IronMan'': During the "Extremis" six-issue arc, Tony Stark modified the titular virus to store his armor inside his body, directly interface with technology, use some of its powers without manifesting it, enhanced reflexes and regeneration of both his body and armor.
** He later develops Extremis 3.0, which grants him the ability to alter his appearance, HealingFactor, Enhanced Strength, Agility and Reflexes. He also claimed it can make people immortal.

to:

* ''ComicBook/IronMan'': During the "Extremis" six-issue arc, Tony Stark modified the titular virus to store his armor inside his body, directly interface with technology, use some of its powers without manifesting it, enhanced reflexes and regeneration of both his body and armor. \n** He later develops Extremis 3.0, which grants him the ability to alter his appearance, HealingFactor, Enhanced Strength, Agility and Reflexes. He also claimed it can make people immortal.



[[folder: Light Novel]]
* ''LightNovel/ACertainMagicalIndex: ''
** Level Six Shift was claimed by Kihara Gensei to used to give Aleister Crowley this, though it remains unknown whether it is true.
** As a Side Effect of being the creator and controller of the Level Upper, Kiyama Harumi gains multi-skill, the ability to use the skills and powers of its users. Kihara Gensei later creates his own version.
** Becoming a Magic God involves "mastering a path to the very end" and becoming a nigh-omnipotent RealityWarper.

to:

[[folder: Light Novel]]
[[folder:Live-Action TV]]
* ''LightNovel/ACertainMagicalIndex: ''
** Level Six Shift was claimed by Kihara Gensei to used to give Aleister Crowley this, though it remains unknown whether it is true.
''Series/TheTomorrowPeople2013'': Jedikiah Price, an EvilutionaryBiologist, narrows down the superhuman gene and artificially "breaks out", gaining considerable psychic powers.
** As a Side Effect of being * In the creator third season premiere of ''Series/{{Heroes}}'', Mohinder Suresh takes a syringe of Maya's blood/DNA/super-powered-{{Phlebotinum}} out onto a dock all by himself and controller of the Level Upper, Kiyama Harumi gains multi-skill, the ability to use the skills and powers of its users. Kihara Gensei later creates his own version.
** Becoming a Magic God involves "mastering a path to the very end" and
injects it into himself, becoming a nigh-omnipotent RealityWarper.case of ProfessorGuineaPig; He gets insect-like super-strength, agility, and wall-climbing ability, but as a side effect appears to be mutating uncontrollably. Once the perfected formula he develops washes over him, he gains superhuman strength.



[[folder: Web Novel]]
* ''{{Literature/Worm}}'':

to:

[[folder: Web Novel]]
[[folder:Web Original]]
* ''{{Literature/Worm}}'': ''Literature/{{Worm}}'':



[[folder: Live-Action TV]]
* ''Series/TheTomorrowPeople2013'': Jedikiah Price, an EvilutionaryBiologist, narrows down the superhuman gene and artificially "breaks out", gaining considerable psychic powers.
* In the third season premiere of ''Series/{{Heroes}}'', Mohinder Suresh takes a syringe of Maya's blood/DNA/super-powered-{{Phlebotinum}} out onto a dock all by himself and injects it into himself, becoming a case of ProfessorGuineaPig; He gets insect-like super-strength, agility, and wall-climbing ability, but as a side effect appears to be mutating uncontrollably. Once the perfected formula he develops washes over him, he gains superhuman strength.
[[/folder]]

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* Anime/DragonBallZ:

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* Anime/DragonBallZ: ''Anime/DragonBallZ'':







* LightNovel/ACertainMagicalIndex:

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\n* LightNovel/ACertainMagicalIndex: ''LightNovel/ACertainMagicalIndex: ''




** As a Side Effect of being the creator and controller of the Level Upper, Kiyama Harumi gains multi-skill, the ability to use the skills and powers of its users.

*** Kihara Gensei later creates his own version.

to:

\n** As a Side Effect of being the creator and controller of the Level Upper, Kiyama Harumi gains multi-skill, the ability to use the skills and powers of its users. \n\n*** Kihara Gensei later creates his own version.
version.










* {{Literature/Worm}}: The following Tinkerers, people with the ability to create advanced technology exceeding contemporary ones.

** Armsmaster as Defiant, replaced his internal organs and parts of his brain with artificial equivalents, reducing his need to sleep, eat and eliminate waste to less than fifteen minutes a day.

** Mannequin a tinker who specialized in sustaining life, modified himself to have inhuman reflexes, Internal Rifle, Multiple arms and various types of lethal gas.

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\n* {{Literature/Worm}}: The following Tinkerers, people with the ability to create advanced technology exceeding contemporary ones.

''{{Literature/Worm}}'':
** Armsmaster Armsmaster, as Defiant, replaced his internal organs and parts of his brain with artificial equivalents, reducing his need to sleep, eat and eliminate waste to less than fifteen minutes a day.

day.
** Mannequin Mannequin, a tinker who specialized in sustaining life, modified himself to have inhuman reflexes, Internal Rifle, Multiple arms and various types of lethal gas.
gas.










* Series/TheTomorrowPeople2013: Jedikiah Price, an EvilutionaryBiologist, narrows down the superhuman gene and artificially "breaks out", gaining considerable psychic powers.

to:

\n* Series/TheTomorrowPeople2013: ''Series/TheTomorrowPeople2013'': Jedikiah Price, an EvilutionaryBiologist, narrows down the superhuman gene and artificially "breaks out", gaining considerable psychic powers.
powers.










* Rick Sanchez of the WesternAnimation/RickAndMorty fame grafts cybernetic parts into himself, though the exact effects remain unknown.

* Professor Membrane from WesternAnimation/InvaderZim replaced his arms with cybernetics of his own inventions capable of firing energy blasts.

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\n* Rick Sanchez of the WesternAnimation/RickAndMorty ''WesternAnimation/RickAndMorty'' fame grafts cybernetic parts into himself, though the exact effects remain unknown.

* Professor Membrane from WesternAnimation/InvaderZim replaced his arms with cybernetics of his own inventions capable of firing energy blasts.
unknown.
* Professor Membrane from ''WesternAnimation/InvaderZim'' replaced his arms with cybernetics of his own inventions capable of firing energy blasts.

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* ''Anime/{{Naruto}}''

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\n* ''Anime/{{Naruto}}''
''Anime/{{Naruto}}'':













* ''Manga/{{Bleach}}''

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\n* ''Manga/{{Bleach}}''
''Manga/{{Bleach}}'':













** Dr, Gero is so brilliant that he creates multiple cyborgs and Android more powerful than the second strongest being in the universe, Freeza and the strongest Super Saiyans '' without ever leaving the Earth'', a very remote and weak planet. He then converts himself into a cyborg.

** Dr. Wheelo from the movie Anime/DragonBallZTheWorldsStrongest is much like Dr.Gero, a brilliant scientist. HE transplanted his brain into a mecha. His goal is to take over Goku's body.

* Kengan Asura gives us Hanafusa Hajime, a CombatMedic who modified his body to have wolverine-style claws, air canisters in his foot to increase speed and power of his kicks, immunity to pain, a device to prevent his heart from stopping, and several others.

* Manga/OnePiece: Franky performed self-surgery on himself twice and turned himself into a cyborg, despite not specializing in it (he is a shipwright), and displays superhuman strength, durability, and hearing. His cyborg body also has its own arsenal.

* Giovanni of Manga/FireForce modified his body can transform into countless firebugs, gaining insect-like traits to increase his strength even further. Even when decapitated, he still survives as his head can move according to his thoughts.


to:

\n** Dr, Gero is so brilliant that he creates multiple cyborgs and Android more powerful than the second strongest being in the universe, Freeza and the strongest Super Saiyans '' without ever leaving the Earth'', a very remote and weak planet. He then converts himself into a cyborg.\n\n** Dr. Gero is so brilliant that he creates multiple cyborgs and Android more powerful than the second strongest being in the universe, Freeza and the strongest Super Saiyans '' without ever leaving the Earth'', a very remote and weak planet. He then converts himself into a cyborg.
** Dr.
Wheelo from the movie Anime/DragonBallZTheWorldsStrongest ''Anime/DragonBallZTheWorldsStrongest'' is much like Dr.Gero, a brilliant scientist. HE transplanted his brain into a mecha. His goal is to take over Goku's body. \n\n
* Kengan Asura ''Manga/KenganAsura'' gives us Hanafusa Hajime, a CombatMedic who modified his body to have wolverine-style claws, air canisters in his foot to increase speed and power of his kicks, immunity to pain, a device to prevent his heart from stopping, and several others.

others.
* Manga/OnePiece: ''Manga/OnePiece'': Franky performed self-surgery on himself twice and turned himself into a cyborg, despite not specializing in it (he is a shipwright), and displays superhuman strength, durability, and hearing. His cyborg body also has its own arsenal. \n\n
* Giovanni of Manga/FireForce ''Manga/FireForce'' modified his body can transform into countless firebugs, gaining insect-like traits to increase his strength even further. Even when decapitated, he still survives as his head can move according to his thoughts. \n\n
















*** He later develops Extremis 3.0, which grants him the ability to alter his appearance, HealingFactor, Enhanced Strength, Agility and Reflexes. He also claimed it can make people immortal.

* {{ComicBook/Thanos}}: Creator/MarvelComics Supervillain Thanos uses his considerable intellect to argument his powers through bionic modifications.

* Nathaniel Essex, better known as Mr. Sinister of {{ComicBook/XMen}}, gave himself quite a few powers by implanting x-genes of other mutants, such as shapeshifting.

* Henry McCoy (Earth-295) of {{ComicBook/XMen}}, better knows as Dark Beast, continuously experimented on himself and others and gained Superhuman Strength, retarded aging, etc. The full extent of his capability remains unknown as he continuously changes them. He also received cybernetic enhancements from Nathaniel Essex, better known as Mr. Sinister.

to:

\n*** ** He later develops Extremis 3.0, which grants him the ability to alter his appearance, HealingFactor, Enhanced Strength, Agility and Reflexes. He also claimed it can make people immortal. \n\n
* {{ComicBook/Thanos}}: Creator/MarvelComics Supervillain Thanos ComicBook/{{Thanos}} uses his considerable intellect to argument his powers through bionic modifications.

modifications.
* ''ComicBook/{{XMen}}'':
**
Nathaniel Essex, better known as Mr. Sinister of {{ComicBook/XMen}}, Sinister, gave himself quite a few powers by implanting x-genes X-genes of other mutants, such as shapeshifting.

*
shapeshifting.
**
Henry McCoy (Earth-295) of {{ComicBook/XMen}}, [=McCoy=](Earth-295), better knows known as Dark Beast, continuously experimented on himself and others and gained Superhuman Strength, retarded SuperStrength, slowed aging, etc. The full extent of his capability remains unknown as he continuously changes them. He also received cybernetic enhancements from Nathaniel Essex, better known as Mr. Sinister.
Sinister.
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* ComicBook/EobardThawne of Comicbook/Flash is a brilliant scientist who recreated the incident that gave the Flash his powers.

to:

* ComicBook/EobardThawne of Comicbook/Flash ''ComicBook/TheFlash'' is a brilliant scientist who recreated the incident that gave the Flash his powers.
** The first Kid Flash, ComicBook/WallyWest, did the same thing to gain his.
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Added DiffLines:

So you are a born genius? Do you possess SuperIntelligence? You can create reality-bending, physics-defying, impossibly complex machines before lunch?

There is one thing you are short on though. You have no superpowers or even the skills of a BadassNormal. Or you just want to surpass your peers. Or maybe you do, but there is AlwaysSomeoneBetter.

The solution is simple. Use your incredibly advanced mind to give yourself powers. Create a ritual because it's TimeToUnlockMoreTruePotential that only the ChosenOne is entitled to. Build a device to mutate your genes into that of the resident RealityWarper. Integrate the {{Magitek}} you have stolen to your brain. Develop a serum to give yourself TheGift and become an InstantExpert.

Done? Great! Now your powers match your intelligence.

The key point is that the character does the upgrading to themselves by giving themselves innate superpowers by themselves and can do so safely.

Not to be confused with ProfessorGuineaPig, which is about testing inventions on themselves while these people know what they are doing.

Compare CharlesAtlasSuperpower, when vigorous training is used to gain superpowers.
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!!Examples:

[[foldercontrol]]

[[folder:Anime and Manga]]

* ''Anime/{{Naruto}}''

** Orochimaru, a brilliant scientist, gives himself powerful BioAugmentation, making himself immortal, be able to shed his body like a snake, and strong enough to fight Naruto in 3 tails form, without his jutsu.

** Orochimaru's right-hand man and highly skilled spy and CombatMedic, Yakushi Kabuto, integrated multiple Kekkei Genkai (unique abilities) into himself, granting him among others, a powerful HealingFactor, ability to liquefy, create a clone, use a SuperMode indefinitely along with becoming a MasterOfIllusion capable of overcoming Itachi and Sauske Uchiha simultaneously.

** Madara Uchiha, unlike his rival Senju Hashirama, is a brilliant scientist and to surpass him, integrated Hashirama's DNA in him, granting himself his rival's signature Wood Release technique and most importantly, the eyes of the God of Shinobi. See his page for the full list.

** Obito Uchiha is a skilled surgeon and well-versed with genetics and transplants. He made up for his lack of natural talent by mastering Hashirama's cell, allowing him to phase through all attacks for 10 minutes with 1 Sharingan, and later transplants a Rinnegan stolen from Nagato's corpse.

* ''Manga/{{Bleach}}''

** TheChessmaster and OmnidisciplinaryScientist extraordinaire Kisuke Urahara invents a device that allows him to achieve the final form of his sword within 3 days, something that takes a decade for even the most gifted Shinigami.

** Mayuri Kurotsuchi, a MadScientist takes this a step further. Being a scientist first and foremost but needing combat prowess he used his brilliant mind to upgrade his Shinigami abilities. As Urahara Kisuke's successor as the Head of Shinigami Research Institute, he gave himself the ability to liquefy and make himself immune to any attack, a grappling hook in his arm and a scythe that extends from his ear. He also created something that allowed himself to achieve Bankai the non-traditional way. Additionally, he installed a censor on his sword that can perfectly block any attack, making up for his lack of swordsmanship skills.

** Aizen Sosuke created the Hogyoku to break the limit of Shinigami potential and steals Kisuke Urahara's, the only person he acknowledges to be smarter than him, to create a single one. He gains so many transformations and powers that it is best to see his page.

* Anime/DragonBallZ:

** Dr, Gero is so brilliant that he creates multiple cyborgs and Android more powerful than the second strongest being in the universe, Freeza and the strongest Super Saiyans '' without ever leaving the Earth'', a very remote and weak planet. He then converts himself into a cyborg.

** Dr. Wheelo from the movie Anime/DragonBallZTheWorldsStrongest is much like Dr.Gero, a brilliant scientist. HE transplanted his brain into a mecha. His goal is to take over Goku's body.

* Kengan Asura gives us Hanafusa Hajime, a CombatMedic who modified his body to have wolverine-style claws, air canisters in his foot to increase speed and power of his kicks, immunity to pain, a device to prevent his heart from stopping, and several others.

* Manga/OnePiece: Franky performed self-surgery on himself twice and turned himself into a cyborg, despite not specializing in it (he is a shipwright), and displays superhuman strength, durability, and hearing. His cyborg body also has its own arsenal.

* Giovanni of Manga/FireForce modified his body can transform into countless firebugs, gaining insect-like traits to increase his strength even further. Even when decapitated, he still survives as his head can move according to his thoughts.


[[/folder]]

[[folder: Comic Book]]

* In ''ComicBook/DarkNightsMetal'', The Drowned modified her body to give herself the superhuman abilities of an Atlantean. She uses them to murder Aquawoman in cold blood, supposedly to stop an inevitable Atlantean invasion, out of her paranoia against metahumans. This is despite being [[YouAreWhatYouHate a metahuman herself.]]

* In ''ComicBook/FiftyTwo'', ComicBook/LexLuthor's "Everyman" initiative is ultimately revealed to be a trial run for giving himself superpowers.
* In ''ComicBook/TheWildStorm'', genius Dr. Angela Spica accidentally kicks off an arms race between two clandestine organizations when she manages to create a "transdermal drysuit" - essentially a retractable suit of armor housed in pieces beneath her skin - by reverse-engineering technology she had observed in an alien ship.

* ComicBook/EobardThawne of Comicbook/Flash is a brilliant scientist who recreated the incident that gave the Flash his powers.

* ''ComicBook/IronMan'': During the "Extremis" six-issue arc, Tony Stark modified the titular virus to store his armor inside his body, directly interface with technology, use some of its powers without manifesting it, enhanced reflexes and regeneration of both his body and armor.

*** He later develops Extremis 3.0, which grants him the ability to alter his appearance, HealingFactor, Enhanced Strength, Agility and Reflexes. He also claimed it can make people immortal.

*{{ComicBook/Thanos}}: Creator/MarvelComics Supervillain Thanos uses his considerable intellect to argument his powers through bionic modifications.

* Nathaniel Essex, better known as Mr. Sinister of {{ComicBook/XMen}}, gave himself quite a few powers by implanting x-genes of other mutants, such as shapeshifting.

* Henry McCoy (Earth-295) of {{ComicBook/XMen}}, better knows as Dark Beast, continuously experimented on himself and others and gained Superhuman Strength, retarded aging, etc. The full extent of his capability remains unknown as he continuously changes them. He also received cybernetic enhancements from Nathaniel Essex, better known as Mr. Sinister.

[[/folder]]


[[folder: Light Novel]]

* LightNovel/ACertainMagicalIndex:
**Level Six Shift was claimed by Kihara Gensei to used to give Aleister Crowley this, though it remains unknown whether it is true.

** As a Side Effect of being the creator and controller of the Level Upper, Kiyama Harumi gains multi-skill, the ability to use the skills and powers of its users.

*** Kihara Gensei later creates his own version.

** Becoming a Magic God involves "mastering a path to the very end" and becoming a nigh-omnipotent RealityWarper.

[[/folder]]


[[folder: Web Novel]]

* {{Literature/Worm}}: The following Tinkerers, people with the ability to create advanced technology exceeding contemporary ones.

** Armsmaster as Defiant, replaced his internal organs and parts of his brain with artificial equivalents, reducing his need to sleep, eat and eliminate waste to less than fifteen minutes a day.

** Mannequin a tinker who specialized in sustaining life, modified himself to have inhuman reflexes, Internal Rifle, Multiple arms and various types of lethal gas.

** Bonesaw can emit deadly toxins and poisons from her body. She is immune to her own poisons and other diseases.

[[/folder]]


[[folder: Live-Action TV]]

* Series/TheTomorrowPeople2013: Jedikiah Price, an EvilutionaryBiologist, narrows down the superhuman gene and artificially "breaks out", gaining considerable psychic powers.

* In the third season premiere of ''Series/{{Heroes}}'', Mohinder Suresh takes a syringe of Maya's blood/DNA/super-powered-{{Phlebotinum}} out onto a dock all by himself and injects it into himself, becoming a case of ProfessorGuineaPig; He gets insect-like super-strength, agility, and wall-climbing ability, but as a side effect appears to be mutating uncontrollably. Once the perfected formula he develops washes over him, he gains superhuman strength.

[[/folder]]


[[folder:Western Animation]]

* Rick Sanchez of the WesternAnimation/RickAndMorty fame grafts cybernetic parts into himself, though the exact effects remain unknown.

* Professor Membrane from WesternAnimation/InvaderZim replaced his arms with cybernetics of his own inventions capable of firing energy blasts.

[[/folder]]
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