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This is a specific subset of the classic EldritchAbomination that is not a naturally-existing being, but was created and cultivated artificially, usually through genetic engineering. That doesn't make them any less horrifying -- and in some cases, it could make them ''more'' so, since they are so different from the natural organisms used in their creation and proves how powerful their creator's capabilities '''''really''''' are. Their resemblance to natural organisms varies. At best, they'll just look like a [[UncannyValley warped version]] of the creatures they were derived from, putting them in AnimalisticAbomination territory. Other times, though, they'll bear absolutely no resemblance whatsoever to anything that ever evolved naturally.

The ''reasons'' for the creation of such a being is variable. Often it's some sort of [[BioweaponBeast living weapon]] that the creator would proclaim as their MagnumOpus, but it's also common for them to be created for other purposes. Note that to qualify for this trope, a creature cannot merely be a large, terrifying genetically engineered beast -- it must also fit into the established definition of an EldritchAbomination. This entails being inconceivably horrific for the majority of minds that encounter it, but in a step-down from a natural abomination not inconceivable to the mortal mind in general, as it was a ''certain'' kind of thinking that brought it to existence after all.

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This is a specific subset of the classic EldritchAbomination that is not a naturally-existing being, but was created and cultivated artificially, usually through genetic engineering. That doesn't make them any less horrifying -- and in some cases, it could make them ''more'' so, since they are so different from the natural organisms used in their creation and proves how powerful their creator's capabilities '''''really''''' are. Their resemblance to natural organisms varies. At best, they'll just look like a [[UncannyValley warped version]] of the creatures that they were derived from, putting them in AnimalisticAbomination territory. Other times, though, they'll bear absolutely no resemblance whatsoever to anything that ever evolved naturally.

The ''reasons'' for the creation of such a being is are variable. Often it's some sort of [[BioweaponBeast living weapon]] that the creator would proclaim as their MagnumOpus, but it's also common for them to be created for other purposes. Note that to qualify for this trope, a creature cannot merely be a large, terrifying genetically engineered beast -- beast-- it must also fit into the established definition of an EldritchAbomination. This entails being inconceivably horrific for the majority of minds that encounter it, but in (in a step-down from a natural abomination abomination) not inconceivable to the mortal mind in general, as general; after all, it was a ''certain'' kind of mortal thinking that brought it to existence after all.
into existence.
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-> ''"(Shambles up to the mic) I escaped from the petri dish...WHAT AM I!?!"''
-->-- '''Russel Howard''', ''Series/MockTheWeek'' ''("Unlikely Things to Hear on a Science Documentary")''

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-> ''"(Shambles up to the mic) I ->''"I escaped from the petri dish...dish... WHAT AM I!?!"''
I!?"''
-->-- '''Russel Howard''', ''Series/MockTheWeek'' ''("Unlikely ''Series/MockTheWeek'', "Unlikely Things to Hear on a Science Documentary")''
Documentary"

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* The ''ComicBook/UltimateSpiderMan'' version of Venom is a cure for cancer turned experimental bio weapon. It can shapeshift to point that it’s practically a BlobMonster at times and actively eats its host unless it consumes a constant amount of human flesh.

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* ''ComicBook/UltimateSpiderMan'':
**
The ''ComicBook/UltimateSpiderMan'' version of Venom ComicBook/{{Venom}} symbiote is a cure for cancer turned experimental bio weapon. bioweapon. It can shapeshift to point that it’s practically a BlobMonster at times and actively eats its host unless it consumes a constant amount of human flesh.flesh.
** The ComicBook/{{Carnage}} symbiote is the result of Dr. Curt Connors mixing a sample of Spider-Man's blood (which contained trace amounts of the Venom symbiote) with his own (which contained the Lizard serum) and a leftover sample of Richard Parker's Venom Project. The result is a blood-red monstrosity that needs to drain other living creatues of their blood and body fluids to sustain itself.
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* The ComicBook/UltimateSpiderMan version of Venom is a cure for cancer turned experimental bio weapon. It can shapeshift to point that it’s practically a BlobMonster at times and actively eats its host unless it consumes a constant amount of human flesh.

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* The ComicBook/UltimateSpiderMan ''ComicBook/UltimateSpiderMan'' version of Venom is a cure for cancer turned experimental bio weapon. It can shapeshift to point that it’s practically a BlobMonster at times and actively eats its host unless it consumes a constant amount of human flesh.
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* The {{ComicBook/UltimateSpiderMan}}’s version of Venom is a cure for cancer turned experimental bio weapon. It can shapeshift to point that it’s practically a BlobMonster at times and actively eats its host unless it consumes a constant amount of human flesh.

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* The {{ComicBook/UltimateSpiderMan}}’s ComicBook/UltimateSpiderMan version of Venom is a cure for cancer turned experimental bio weapon. It can shapeshift to point that it’s practically a BlobMonster at times and actively eats its host unless it consumes a constant amount of human flesh.
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* The {{ComicBook/UltimateSpiderMan}}’s version of Venom is a cure for cancer turned experimental bio weapon. It can shapeshift to point that it’s practically a BlobMonster at times and actively eats its host unless it consumes a constant amount of human flesh.
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Up To Eleven is a defunct trope


* ''VideoGame/DragonBallFighterZ'': Android 21 is Cell turned UpToEleven. She's an even bigger amalgamation of several powerful beings and scientists, including Cell himself. This gives her the potential to be far more powerful than Cell could ever be, access to an even bigger arsenal of tricks, and high intellect to match. However, due to her being partially made from cells originating from Majin Buu, Android 21 is in a near-constant state of hunger that she tries so hard to suppress. This makes her a threat not only to Earth, but the entire universe unless she is stopped in some way.

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* ''VideoGame/DragonBallFighterZ'': Android 21 is Cell turned UpToEleven. She's an even bigger amalgamation of several powerful beings and scientists, including Cell himself. This gives her the potential to be far more powerful than Cell could ever be, access to an even bigger arsenal of tricks, and high intellect to match. However, due to her being partially made from cells originating from Majin Buu, Android 21 is in a near-constant state of hunger that she tries so hard to suppress. This makes her a threat not only to Earth, but the entire universe unless she is stopped in some way.
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Edited quote for accuracy.


-->-- '''Russel Howard''', ''Series/MockTheWeek'' ''("Things You Wouldn't Hear on a Science Programme")''

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-->-- '''Russel Howard''', ''Series/MockTheWeek'' ''("Things You Wouldn't ''("Unlikely Things to Hear on a Science Programme")''
Documentary")''
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Changed quote.


-> '''Peppy:''' THIS is the enemy's bio-weapon!?
-> '''Falco:''' Andross is an insane Fool!
-->--''VideoGame/StarFox64'' on Vulcain.

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-> '''Peppy:''' THIS is ''"(Shambles up to the enemy's bio-weapon!?
-> '''Falco:''' Andross is an insane Fool!
-->--''VideoGame/StarFox64''
mic) I escaped from the petri dish...WHAT AM I!?!"''
-->-- '''Russel Howard''', ''Series/MockTheWeek'' ''("Things You Wouldn't Hear
on Vulcain.a Science Programme")''
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-> '''Peppy:''' THIS is the enemy's bio-weapon!?\\

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-> '''Peppy:''' THIS is the enemy's bio-weapon!?\\ bio-weapon!?
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-> '''Peppy:''' THIS is the enemy's bio-weapon!?\\
-> '''Falco:''' Andross is an insane Fool!
-->--''VideoGame/StarFox64'' on Vulcain.

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Formatting and alphabetization.


* ''[[https://tvtropes.org/pmwiki/pmwiki.php/Literature/Frankenstein Frankenstein]]'': Quite possibly the TropeCodifier of this trope, a very large portion of genetic abominations have been influenced by the classic creature himself- Frankenstein's monster. Though his intentions and personality are completely different (he does have an intelligent human mind), his basic concept is still incredibly important.


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* ''Literature/{{Frankenstein}}'': Quite possibly the TropeCodifier of this trope, a very large portion of genetic abominations have been influenced by the classic creature himself- Frankenstein's monster. Though his intentions and personality are completely different (he does have an intelligent human mind), his basic concept is still incredibly important.
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* ''[[https://tvtropes.org/pmwiki/pmwiki.php/Literature/Frankenstein Frankenstein]]'': Quite possibly the TropeCodifier of this trope, a very large portion of genetic abominations have been influenced by the classic creature himself- Frankenstein's monster. Though his intentions and personality are completely different (he does have an intelligent human mind), his basic concept is still incredibly important.
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Adding it to the article proper since 10 days have passed. Hope it's okay


%%[[folder:Real Life]]
%%* Though its occurence is almost never artificial, cancer counts. The name itself strikes fear to those who are diagnosed with it, and though much study have been done to understand it, many still die of it every year.\\
%%\\
%%A GeneticAbomination borne of mutations, its physical form is just as aberrant; malformed tumors and patchwork vessels made of both healthy and rogue cells. It will continue to grow, eventually spreading its invasive tendrils to other organs, choking and killing them, and thus, their host. It is invasive while being evasive, fooling the immune cells from killing it, and able to spread to other loci, seeding a new mass of malformed flesh FromASingleCell. Some tumors are able to differentiate their cells ''just'' enough to grow organs like hair and teeth in random spots, making them praticularly grotesque. The fact that its diagnosis often justify HarmfulHealing is testament to its [[TheDreaded dreaded status]]; treatments that will cause ''severe'' damage to healthy cells is considered acceptable trade-off in the attempt to kill this abomination off, and sometimes even that's not enough.
%%[[/folder]]

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%%[[folder:Real [[folder:Real Life]]
%%* * Though its occurence is almost never artificial, cancer counts. The name itself strikes fear to those who are diagnosed with it, and though much study have been done to understand it, many still die of it every year.\\
%%\\
%%A
\\
A
GeneticAbomination borne of mutations, its physical form is just as similarly aberrant; malformed tumors and patchwork vessels made vessels, unholy fusion of both healthy and rogue cells. It will continue to grow, eventually spreading its invasive tendrils to other organs, choking and killing them, and thus, their host. It is invasive while being yet evasive, fooling preventing the immune cells from killing it, and able to spread to other loci, seeding a new mass masses of malformed flesh FromASingleCell. Some tumors are even able to differentiate their cells ''just'' enough to grow organs like hair and teeth in random spots, making them praticularly particularly grotesque. The fact that its diagnosis often justify HarmfulHealing is testament to its [[TheDreaded dreaded status]]; treatments that will cause ''severe'' damage to healthy cells is considered acceptable trade-off in the attempt to kill this abomination off, and sometimes even that's not enough.
%%[[/folder]][[/folder]]
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%%A GeneticAbomination borne of mutations, its physical form is just as aberrant; malformed tumors and patchwork vessels made of both healthy and rogue cells. It will continue to grow, eventually spreading its invasive tendrils to other organs, choking and killing them, and thus, their host. It is invasive while being evasive, fooling the immune cells from killing it, and able to spread to other loci, seeding a new mass of malformed flesh FromASingleCell. The fact that its diagnosis often justify HarmfulHealing is testament to its [[TheDreaded dreaded status]]; treatments that will cause ''severe'' damage to healthy cells is considered acceptable trade-off in the attempt to kill this abomination off, and sometimes even that's not enough.

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%%A GeneticAbomination borne of mutations, its physical form is just as aberrant; malformed tumors and patchwork vessels made of both healthy and rogue cells. It will continue to grow, eventually spreading its invasive tendrils to other organs, choking and killing them, and thus, their host. It is invasive while being evasive, fooling the immune cells from killing it, and able to spread to other loci, seeding a new mass of malformed flesh FromASingleCell. Some tumors are able to differentiate their cells ''just'' enough to grow organs like hair and teeth in random spots, making them praticularly grotesque. The fact that its diagnosis often justify HarmfulHealing is testament to its [[TheDreaded dreaded status]]; treatments that will cause ''severe'' damage to healthy cells is considered acceptable trade-off in the attempt to kill this abomination off, and sometimes even that's not enough.
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Added RL section of cancer; I think it should count given how irregular and dreaded it is, even if it's not artificial most of the time. I've commented out the entry for now, if anyone could take a look and see if it's appropriate. (I was also trying to be dramatic with its description.)

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%%[[folder:Real Life]]
%%* Though its occurence is almost never artificial, cancer counts. The name itself strikes fear to those who are diagnosed with it, and though much study have been done to understand it, many still die of it every year.\\
%%\\
%%A GeneticAbomination borne of mutations, its physical form is just as aberrant; malformed tumors and patchwork vessels made of both healthy and rogue cells. It will continue to grow, eventually spreading its invasive tendrils to other organs, choking and killing them, and thus, their host. It is invasive while being evasive, fooling the immune cells from killing it, and able to spread to other loci, seeding a new mass of malformed flesh FromASingleCell. The fact that its diagnosis often justify HarmfulHealing is testament to its [[TheDreaded dreaded status]]; treatments that will cause ''severe'' damage to healthy cells is considered acceptable trade-off in the attempt to kill this abomination off, and sometimes even that's not enough.
%%[[/folder]]
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* In ''WesternAnimation/StarTrekLowerDecks'' Tendi creates [[SpellMyNameWithAThe The Dog]], a [[LovecraftianSuperPower Shapeshifting]] Labrador Retriever.

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* In ''WesternAnimation/StarTrekLowerDecks'' Tendi creates [[SpellMyNameWithAThe The Dog]], a [[LovecraftianSuperPower Shapeshifting]] Labrador Retriever. Being an alien, she had no idea what an Earth dog could actually ''do'', so she ended up giving The Dog a bunch of freaky powers ''[[AchievementsInIgnorance by mistake]]''.
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* ''VideoGame/HorizonForbiddenWest'' has this as the final fate of [[spoiler:[[PredecessorVillain Theodor "Ted" Faro]]]]. Courtesy of a botched longevity treatment, by one thousand years after the end of the world, he is a [[BlobMonster gigantic tumor]] several stories tall. Even those who would have worshiped him recoil in disgust and MercyKill him. With centuries of immobile isolation, he can only howl at people, not even talk. The player doesn't get a good look at him, but judging from the reactions of Aloy and the Ceo, [[TakeOurWordForIt they wouldn't want to]].
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* ''ComicBook/WeKillMonsters'': [[spoiler:All the monstrosities that have been attacking Kern County are animals genetically modified by [[{{MegaCorp}} Tronco]]'s pharmaceutical subsidiaries to produce large amounts of a certain kind of [=DNA=] they intend to put in all the products of the companies Tronco owns for humans to consume.]]
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** Experiment No. Z-57 from ''VideoGame/MetroidDread''. The "abomination" part comes from the fact that it looks like a horrifically mutated lizard with a FlowerMouth, spider-like limbs and a slug-like tail, can breath lasers that leave some sort of goop behind, and clogged the heat generator with said goop, despite being much smaller than said generator. The "genetic" part comes from the fact that it was created by the Mawkin, with it being made from the DNA of multiple creatures, most obviously a Corpius. This fact is enforced by it not even having an actual name, with it simply being called "Experiment No. Z-57".

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** Experiment No. Z-57 from ''VideoGame/MetroidDread''. The "abomination" part comes from the fact that it looks like a horrifically mutated lizard with a FlowerMouth, spider-like limbs tentacle-limbs and a slug-like tail, can breath lasers that leave some sort of goop behind, and clogged the heat generator with said goop, goop despite being much smaller than said generator. The "genetic" part comes from the fact that it was created by the Mawkin, with it being made from the DNA of multiple creatures, most obviously a Corpius. This fact is enforced by it not even having an actual name, with it simply being called "Experiment No. Z-57".



* ''VideoGame/{{Prototype}}'': The Redlight and Blacklight viruses were engineered as bioweapons and bestow [[LovecraftianSuperpower nightmarish abilities]] on compatible hosts, and mutate anyone who isn't a compatible host into ravenous zombies or predatory monsters connected to a hive-mind. In the second game, a Gentek scientist even lampshades how little about the mutagen makes scientific sense, only to be told to shut up and not think so deeply about it.

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* ''VideoGame/{{Prototype}}'': The Redlight and Blacklight viruses were engineered as bioweapons and bestow [[LovecraftianSuperpower nightmarish abilities]] on compatible hosts, and but mutate anyone who isn't a compatible host into ravenous zombies or predatory monsters connected to a hive-mind. In [[VideoGame/Prototype2 the second game, game]], a Gentek scientist even lampshades how little about the mutagen makes scientific sense, only to be told to shut up and not think so deeply about it.
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Blacklight and Redlight actually are viruses in-universe, it is just their "symptoms" that are decidedly unlike any real virus.


* ''VideoGame/{{Prototype}}'': The Redlight and Blacklight were engineered as bioweapons and are called viruses, but bestow [[LovecraftianSuperpower nightmarish abilities]] on compatible hosts, and mutate anyone who isn't a compatible host into ravenous zombies or predatory monsters connected to a hive-mind. In the second game, a Gentek scientist even lampshades how little about the mutagen makes scientific sense, only to be told to shut up and not think so deeply about it.

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* ''VideoGame/{{Prototype}}'': The Redlight and Blacklight viruses were engineered as bioweapons and are called viruses, but bestow [[LovecraftianSuperpower nightmarish abilities]] on compatible hosts, and mutate anyone who isn't a compatible host into ravenous zombies or predatory monsters connected to a hive-mind. In the second game, a Gentek scientist even lampshades how little about the mutagen makes scientific sense, only to be told to shut up and not think so deeply about it.
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* ''VideoGame/StarcraftII'' has the Hybrids, created by mixing DNA from the [[HigherTechSpecies Protoss]] and the [[HordeOfAlienLocusts Zerg]] in order to serve as servants of and vessels for the rogue [[SufficientlyAdvancedAliens Xel'naga]] [[BigBad Amon]]. The Protoss and Zerg themselves are both products of earlier rounds of Xel'naga engineering.

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* ''VideoGame/StarcraftII'' has the Hybrids, created by mixing DNA from the [[HigherTechSpecies Protoss]] and the [[HordeOfAlienLocusts Zerg]] in order to serve as servants of and vessels for the rogue [[SufficientlyAdvancedAliens Xel'naga]] [[BigBad Amon]]. The Protoss and Zerg [[HordeOfAlienLocusts Zerg]] themselves are both products of earlier rounds of Xel'naga engineering.engineering, and the Zerg qualify for this trope themselves.
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Removed dead links


* The ''VideoGame/{{Fallout}}'' series has a wide variety of mutated eldritch horrors. There's [[https://static.wikia.nocookie.net/fallout/images/b/bc/Centaur.png/revision/latest?cb=20110204015102 Centaurs]], [[https://static.wikia.nocookie.net/fallout/images/7/7f/FO76WL_Floater_gnasher_transparent.png/revision/latest?cb=20200516052654 Floaters]], [[https://static.wikia.nocookie.net/fallout/images/8/87/Fo4-FH-FogCrawler.png/revision/latest?cb=20170324154312 Fog Crawlers]], [[https://static.wikia.nocookie.net/fallout/images/8/87/Mirelurk_fo4.png/revision/latest?cb=20160106231456 Mirelurks]], and who can forget [[https://static.wikia.nocookie.net/fallout/images/d/d1/FO01_NPC_Master_B.png/revision/latest?cb=20110103095213 the Master]]?

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* The ''VideoGame/{{Fallout}}'' series has a wide variety of mutated eldritch horrors. There's [[https://static.wikia.nocookie.net/fallout/images/b/bc/Centaur.png/revision/latest?cb=20110204015102 Centaurs]], [[https://static.wikia.nocookie.net/fallout/images/7/7f/FO76WL_Floater_gnasher_transparent.png/revision/latest?cb=20200516052654 Floaters]], [[https://static.wikia.nocookie.net/fallout/images/8/87/Fo4-FH-FogCrawler.png/revision/latest?cb=20170324154312 Centaur, Floaters, Fog Crawlers]], [[https://static.wikia.nocookie.net/fallout/images/8/87/Mirelurk_fo4.png/revision/latest?cb=20160106231456 Mirelurks]], Crawlers, Mirelurks, and who can forget [[https://static.wikia.nocookie.net/fallout/images/d/d1/FO01_NPC_Master_B.png/revision/latest?cb=20110103095213 the Master]]?unforgettable Master?
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* ''VideoGame/{{Prototype}}'': The Redlight and Blacklight were engineered as bioweapons and are called viruses, but bestow [[LovecraftianSuperpower nightmarish abilities]] on compatible hosts, and mutate anyone who isn't a compatible host into ravenous zombies or predatory monsters connected to a hive-mind. In the second game, a Gentek scientist even lampshades how little about the mutagen makes scientific sense, only to be told to shut up and not think so deeply about it.

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%% Image selected per Image Pickin' thread: https://tvtropes.org/pmwiki/posts.php?discussion=1628358571012031800
%% Please do not replace or remove without starting a new thread.

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%% Image selected per Image Pickin' thread: https://tvtropes.org/pmwiki/posts.php?discussion=1628358571012031800
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[[quoteright:350:[[Franchise/ResidentEvil https://static.tvtropes.org/pmwiki/pub/images/tyrant_9.png]]]]
[[caption-width-right:350: Some [[EldritchAbomination otherworldly horrors]] [[Film/JurassicWorld aren't bred. Some are designed.]]]]

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[[quoteright:350:[[Franchise/ResidentEvil https://static.tvtropes.org/pmwiki/pub/images/tyrant_9.png]]]]
[[caption-width-right:350: Some [[EldritchAbomination otherworldly horrors]] [[Film/JurassicWorld aren't bred. Some are designed.]]]]
%% This page has been alphabetized. Please add new examples in the correct order. Thanks!



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%% Image selected per Image Pickin' thread: https://tvtropes.org/pmwiki/posts.php?discussion=1628358571012031800
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[[quoteright:350:[[Franchise/ResidentEvil https://static.tvtropes.org/pmwiki/pub/images/tyrant_9.png]]]]
[[caption-width-right:350: Some [[EldritchAbomination otherworldly horrors]] [[Film/JurassicWorld aren't bred. Some are designed.]]]]
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* ''Anime/DigimonAdventure'' gives us Kimeramon. Despite being a digital lifeform and not being "real" in a traditional sense, it's a monstrous kitbash of several different Digimon that have been synthesized together.



** Humanity was originally created by [[{{Precursors}} the Uranus]] as a race of soldiers, with an adaptable and intelligent base form that could then be artificially [[{{Metamorphosis}} metamorphosed]] into one of various types of Zoanoid - {{Bioweapon Beast}}s with specialised abilities ranging from brute strength to organic laser cannons. Each human was implanted with a genetic RestrainingBolt which would force them to obey the telepathic commands of both the [[MonsterLord Zoalord commander units]] and their Uranus masters. But when they tried bonding a human with [[OrganicTechnology the bio-boost organism that served as their standard-issue spacesuit]], wanting to see what would happen if it "maximised the host's ability to survive", things [[GoneHorriblyRight Went Horribly Right]]. Not only did the bonding process transform humans into PersonsOfMassDestruction with the combined powers of many Zoanoids, it also made them ImmuneToMindControl. They named the resulting creature "Guyver", meaning "out of control", and became so spooked by [[TemptingFate how easy it was to create one]] that they abandoned Earth entirely (and even attempted to ''destroy'' it out of fear that an army of Guyvers would one day come after them).
** In the modern day, the "Lost Numbers" are byproducts of NebulousEvilOrganisation [[MeaningfulName Chronos]]'s experiments in creating new varieties of Zoanoid, whose DNA became unstable after being augmented too many times. This grants them strange and unique powers, but also disables their Uranian control genes, meaning that anyone unlucky enough to achieve this status ends up relegated to a suicide squad. And then there's Aptom. Formerly a [[VoluntaryShapeshifting shapeshifting]] Lost Number, he somehow mutated into an entirely new form of life - the cells of his body transforming into a HiveMind of ''[[Film/TheThing1982 Thing]]''-like parasites that can take over the bodies of other Zoanoids and mimic their forms. When Aptom needs to fight, he transforms into a ShapeshifterMashup form combining the best aspects of multiple Hyper Zoanoids in a single body. Eventually Aptom [[HeelFaceTurn switches sides and joins the Guyver protagonists]]... and in an IronicEcho of their former masters, Chronos covers up the truth of his creation by claiming that he's a Guyver (which by the original definition, he ''is'').

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** Humanity was originally created by [[{{Precursors}} the Uranus]] as a race of soldiers, with an adaptable and intelligent base form that could then be artificially [[{{Metamorphosis}} metamorphosed]] into one of various types of Zoanoid - -- {{Bioweapon Beast}}s with specialised abilities ranging from brute strength to organic laser cannons. Each human was implanted with a genetic RestrainingBolt which would force them to obey the telepathic commands of both the [[MonsterLord Zoalord commander units]] and their Uranus masters. But when they tried bonding a human with [[OrganicTechnology the bio-boost organism that served as their standard-issue spacesuit]], wanting to see what would happen if it "maximised the host's ability to survive", things [[GoneHorriblyRight Went Horribly Right]]. Not only did the bonding process transform humans into PersonsOfMassDestruction with the combined powers of many Zoanoids, it also made them ImmuneToMindControl. They named the resulting creature "Guyver", meaning "out of control", and became so spooked by [[TemptingFate how easy it was to create one]] that they abandoned Earth entirely (and even attempted to ''destroy'' it out of fear that an army of Guyvers would one day come after them).
** In the modern day, the "Lost Numbers" are byproducts of NebulousEvilOrganisation [[MeaningfulName Chronos]]'s experiments in creating new varieties of Zoanoid, whose DNA became unstable after being augmented too many times. This grants them strange and unique powers, but also disables their Uranian control genes, meaning that anyone unlucky enough to achieve this status ends up relegated to a suicide squad. And then there's Aptom. Formerly a [[VoluntaryShapeshifting shapeshifting]] Lost Number, he somehow mutated into an entirely new form of life - -- the cells of his body transforming into a HiveMind of ''[[Film/TheThing1982 Thing]]''-like parasites that can take over the bodies of other Zoanoids and mimic their forms. When Aptom needs to fight, he transforms into a ShapeshifterMashup form combining the best aspects of multiple Hyper Zoanoids in a single body. Eventually Aptom [[HeelFaceTurn switches sides and joins the Guyver protagonists]]... and in an IronicEcho of their former masters, Chronos covers up the truth of his creation by claiming that he's a Guyver (which by the original definition, he ''is'').



* ''Anime/DigimonAdventure'' gives us Kimeramon. Despite being a digital lifeform and not being "real" in a traditional sense, it's a monstrous kitbash of several different Digimon that have been synthesized together.



* ''Literature/AllTomorrows'': In the distant future, humanity goes to war against the Qu, a race of ScaryDogmaticAliens... and they lose. The Qu punished the survivors by turning them into these. Many of these creations would qualify as WoobieSpecies, such as the [[AndIMustScream Mantelopes]], who were changed into grazing ungulates but retained their human intelligence and sapience -- they cannot talk or do anything in their new bodies but vividly recall their past forms, so they spend their centuries wandering the plains of their world, screaming and singing in despair.



* ''Literature/AllTomorrows'': In the distant future, humanity goes to war against the Qu, a race of ScaryDogmaticAliens... and they lose. The Qu punished the survivors by turning them into these. Many of these creations would qualify as WoobieSpecies, such as the [[AndIMustScream Mantelopes]], who were changed into grazing ungulates but retained their human intelligence and sapience - they cannot talk or do anything in their new bodies but vividly recall their past forms, so they spend their centuries wandering the plains of their world, screaming and singing in despair.



** The Despair Squid, an apex predator resulting from an artificially enhanced evolutionary arms race. "It's got three alternatives - it thinks we're either a threat, food or mate. It's either gonna kill us, eat us or hump us."

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** The Despair Squid, an apex predator resulting from an artificially enhanced evolutionary arms race. "It's got three alternatives - -- it thinks we're either a threat, food or mate. It's either gonna kill us, eat us or hump us."



** Emohawks - semi-domesticated Polymorphs used by the Gelfs to trade emotions, and also to get back at people who cross them.

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** Emohawks - -- semi-domesticated Polymorphs used by the Gelfs to trade emotions, and also to get back at people who cross them.


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** The Metroids are creatures artificially bioengineered by the [[{{Precursors}} Chozo]] to devour the X-Parasites on SR-388, only to turn out to be so ravenous that they started draining the LifeEnergy of everything else on the planet, including their creators.

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** The Metroids are creatures artificially bioengineered by the [[{{Precursors}} Chozo]] to devour the X-Parasites on SR-388, only to turn out to be so ravenous that they started draining the LifeEnergy of everything else on the planet, including their creators. They can metamorphose into different forms depending on their environment, as well.

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* The Metroids of ''Franchise/{{Metroid}}'' are creatures artificially bioengineered by the [[{{Precursors}} Chozo]] to devour the X-Parasites on SR-388, only to turn out to be so ravenous that they started draining the LifeEnergy of everything else on the planet, including their creators.

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* ''Franchise/{{Metroid}}'':
**
The Metroids of ''Franchise/{{Metroid}}'' are creatures artificially bioengineered by the [[{{Precursors}} Chozo]] to devour the X-Parasites on SR-388, only to turn out to be so ravenous that they started draining the LifeEnergy of everything else on the planet, including their creators.creators.
** Experiment No. Z-57 from ''VideoGame/MetroidDread''. The "abomination" part comes from the fact that it looks like a horrifically mutated lizard with a FlowerMouth, spider-like limbs and a slug-like tail, can breath lasers that leave some sort of goop behind, and clogged the heat generator with said goop, despite being much smaller than said generator. The "genetic" part comes from the fact that it was created by the Mawkin, with it being made from the DNA of multiple creatures, most obviously a Corpius. This fact is enforced by it not even having an actual name, with it simply being called "Experiment No. Z-57".
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[[caption-width-right:350: Some [[EldritchAbomination otherworldly horrors]] [[Film/JurassicWorld aren't bred. Some are designed.]]]]

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Linked new trope Custom Built Host in the description.


A SubTrope of GeneticEngineeringIsTheNewNuke, seeing as it was bio-engineering that created these horrors. Likely to overlap with BioweaponBeast if they were created for combat purposes. Might have EscapedFromTheLab. For other artificially created Abominations, see MechanicalAbomination, and if both tropes overlap, the combination results in an unholy example of OrganicTechnology and MeatSackRobot.

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A SubTrope of GeneticEngineeringIsTheNewNuke, seeing as it was bio-engineering that created these horrors. Likely to overlap with BioweaponBeast if they were created for combat purposes.purposes, and can be a CustomBuiltHost for a real Eldritch Abomination. Might have EscapedFromTheLab. For other artificially created Abominations, see MechanicalAbomination, and if both tropes overlap, the combination results in an unholy example of OrganicTechnology and MeatSackRobot.
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* In ''WesternAnimation/StarTrekLowerDecks'' Tendi creates [[SpellMyNameWithAThe The Dog]], a [[LovecraftianSuperPower Shapeshifting]] Labrador Retriever.

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