History Main / ABNegative

** The episode "Your Hit Parade" in Season 6 features an AB- patient during a period of heavy casualties. Hawkeye asks for 4 units during surgery, Klinger informs them they only had 2 to start with and both were used during the first batch of wounded. They mention collecting the patient's blood during surgery to filter and give back to him, then spend the rest of the episode trying to find more. The unavailability of any donors is partly justified by the heavy casualties and the other medical units being forced to bug out, but it is implied there are only 2 other people available to donate in Asia with the correct blood type; not once does anyone suggest using a different blood type, even as an emergency measure. (It also creates a possible ContinuitySnarl with "Life Time" because there's apparently no one in the unit who can donate AB negative blood, but Winchester is already in the unit; even if there's a reason he can't donate at that time -- most likely the unit not being able to afford to have a doctor not at full strength -- you would expect it to at least be ''mentioned''. A further snarl comes with the episode [[Recap/MashS7E20Cave C*A*V*E]], in which Klinger, Mulcahy, and Winchester are all stated to have the same blood type - and Klinger's had already been stated as B+.)

** The episode "Your Hit Parade" in Season 6 features an AB- patient during a period of heavy casualties. Hawkeye asks for 4 units during surgery, Klinger informs them they only had 2 to start with and both were used during the first batch of wounded. They mention collecting the patient's blood during surgery to filter and give back to him, then spend the rest of the episode trying to find more. The unavailability of any donors is partly justified by the heavy casualties and the other medical units being forced to bug out, but it is implied there are only 2 other people available to donate in Asia with the correct blood type; not once does anyone suggest using a different blood type, even as an emergency measure. (It also creates a possible ContinuitySnarl with "Life Time" because there's apparently no one in the unit who can donate AB negative blood, but Winchester is already in the unit; even if there's a reason he can't donate at that time, you would expect it to at least be mentioned. A further snarl comes with the episode [[Recap/MashS7E20Cave C*A*V*E]], in which Klinger, Mulcahy, and Winchester are all stated to have the same blood type - and Klinger's had already been stated as B+.)

* In something of an inversion, 150 people around the world have been found to have an antibody that actually ''prevents'' the immune system from attacking foreign blood types, something that gained a bit of media attention due to the famous case of James Harrison, "The Man with the Golden Arms"; it's still not entirely clear what causes this antibody to develop, but it's believed that Harrison's case specifically was caused by him receiving incompatible blood during a surgery (he needed a large amount of blood and the rural hospital didn't have enough of the right type in stock) and his immune system's reaction to said blood. Plasma from donors with this antibody is used in the manufacture of a treatment to prevent HDFN in Rh-positive children of Rh-negative mothers (which is by far the most common cause of the disorder).

* ''Fanfic/TriptychContinuum'': Since nopony knows for certain whether alicorns can take blood from regular ponies (and it is known that ponies of one tribe cannot recieve blood from another), the Royal Physicians have been taking blood from the Princesses at regular intervals and keeping it under stasis, to be transfused ''back'' in an emergency. They do the same for Tish, since nopony knows whether foreign blood introduced into her body would be incorporated into her self-transformation magic.

* ''"Blood Sickness Of The White Sand Village"'', a story by Creator/JunjiIto deals with a very retired village where the inhabitants look pale and anemic. Among one of the things that the main character notices is that the medical records show that the majority of the villagers have AB type blood. [[spoiler: when he discovers that buried under the village is a system of veins, he takes a sample of the blood running through it, finding that it is also AB type, confirming his suspicions that the villagers' blood gets absorbed by the village itself]].

* In ''Series/TerminatorTheSarahConnorChronicles'', they mentioned that Sarah had O- blood but John had AB- blood; this would mean that she couldn't possibly be his mother, barring vanishingly rare situations like mutation or [[http://en.wikipedia.org/wiki/Hh_antigen_system Bombay blood type.]][[note]]For the record, type O is recessive, and Sarah is therefore by necessity homozygous for O. Johny could be AO (type A) or BO (type B), but type AB is not possible.[[/note]] Sarah being unable to give blood to the AB- Derek Reese despite being a universal donor is correct due to compatibility for plasma being reversed compared to blood cells -- someone with type O is the least useful donor because their plasma could contain antibodies against non-O blood types.

* ''Series/MurdochMysteries'' toys with this concept in the episode "Tour de Murdoch", which takes place in early 1901, ''just'' as ABO blood types were codified among the scientific community. The VictimOfTheWeek -- an athlete who died of complications from blood aggulation -- was found to have been injected with the blood of his teammates (essentially [[https://en.wikipedia.org/wiki/Blood_doping blood doping]] decades before it received mainstream attention), sending the characters on the search for athletes with "the bad kind of blood." As the investigation narrows down, they inadvertently discover the AB blood type (beating the rest of the scientific community in real life by almost a decade), explaining why one combination of blood is lethal while others were not. [[EntertaininglyWrong Though Murdoch hypothetically names it "Type C".]]

* This is a significant plot point in ''Manga/OnePiece'', where Sanji is revealed to have a rare blood type, and Chopper runs out of spare blood for transfusions because Sanji keeps having [[LovableSexManiac incredible nose bleeds,]] prompting a crisis when the Fishmen refuse to donate blood to a human because their law prevents them from doing so.

** Also in the same arc, it's been said that Fisher Tiger died because humans refused to donate their blood for him while his no one from his crew shared the same blood type as him. [[spoiler:The truth, however, was that Tiger refused to accept human blood because of his deep hatred towards humans[[note]]because he was enslaved the Celestial Dragons and was just betrayed by the humans a moment ago[[/note]], and he told his crew not to tell anybody about his hatred in order to minimize the racism towards humans.]]
*** Oh yes, and in One Piece, the blood types seen have been X, F, S, XF, and S RH-.

* The season-two finale of ''Series/{{Monk}}'' featured a victim whose blood group was "AB-negative with a D- antigen -- the rarest blood type in the world!" In fact, [[ArtisticLicenseBiology no such blood type exists]]. [[note]]Although it is possible for certain blood subtypes to show up this way on a test, the one doing the testing should have recognized an impossible result and retested.[[/note]] This turned out to be why he was murdered -- he was a death row inmate about to be executed, with his kidneys earmarked for a dying billionaire. A prison employee had a grudge against the billionaire and couldn't let that happen, so the prisoner's last meal was poisoned, destroying his organs in a way that lethal injection would not.

* In ''VideoGame/{{Yakuza}}'' 4, [[spoiler: Lily's rare blood type is the reason why when she suffered kidney failure, Saejima located her biological father and did whatever it took for him to donate one of his to her]].
* In ''Videogame/DoomEternal'', it's mentioned that the Doom Slayer is AB Positive, though the only significance this has is to confirm that he's a human.

* ''Franchise/{{Dracula}}'':
** ''Literature/{{Dracula}}'', thanks to ScienceMarchesOn. When the book was written, the concept of blood transfusions was radical, cutting-edge science and the possibility of an allergic reaction to someone else's blood wasn't known. Thus, Lucy can get transfusions from four different men without anyone worrying about blood type compatibility. Since she's in the process of becoming a vampire, blood types may be irrelevant to her in a very easy retcon. Another easy FanWank is to claim that Lucy is AB+ (one of the rarest types), the "universal recipient."
** Creator/FredSaberhagen's PerspectiveFlip ''Literature/TheDraculaTape'' makes use of this; while his Dracula did drink from Lucy, it was the blood transfusion that was killing her.
** Also theorized in ''Literature/AnnoDracula''.
** One of the annotations in ''TabletopGame/TheDraculaDossier'' (specifically in ''Dracula Unredacted'') suggests that the first stage of vampiric transformation changes the proto-vamp's blood type to AB+ (universal recipient), meaning Lucy could have survived those transfusions if they'd been able to keep Dracula away from her.