History MadScientist / ComicBooks

* The scientists that captured N°73 in ''ComicBook/BlackTears'' have kidnapped countless children (if our protagonist number means anything, almost a hundred) and turned them all into monsters, all with the purpose of creating what they fear more: [[EldritchAbomination the darkness]]. They are stereotypical one-note madmen, with them having spiral glasses, not different from [[WebVideo/TheSpoonyExperiment Dr.Insano]], and we don't know how or why they got funded for their research, or why they even decided to give a body to an entity they fear.

* Dr. Venom in ''ComicBook/TransformersVsGIJoe'' ([[PronouncingMyNameForYou pronounced Phe-nom]]) is mad [[UpToEleven and then some]], which is why the Joes (and later their allies, the Autobots) don't trust him after they liberate him from Cobra, even after [[spoiler: he shoots Buzzer in the head]]. He doesn't exactly give them much reason to trust him, either.

* Rhona Burchill from ''ComicBook/UltimateFantasticFour''. She was rejected from the Program despite having the natural talents as a scientist, implicitly due to failing the psychiatric evaluation -- since she went on to cut her brother's brain out and graft it to her own, justifiably so. As for what makes her mad... did you just read the previous sentence?

* In ''ComicBook/YTheLastMan'' geneticist Dr Allison Mann claims she was illegally cloning a nephew who needed a bone transplant. She later admits this story was fictional to gain Agent 355's sympathy rather than be thought of as a 'mad scientist'; her actual motive was to spite her father who was nearing success in cloning the first human. [[spoiler: After several red herrings we discover the REAL mad scientist is in fact Allison's father, who was seeking to clone his daughter so he could be a better parent the next time round, yet who also sabotaged Allison's cloning experiment out of sheer spite and may have accidentally caused the plague that all but wiped out all males.]]

* Dr. Venom in ''ComicBook/TransformersVsGIJoe'' ([[ItIsPronouncedTroPAY pronounced Phe-nom]]) is mad [[UpToEleven and then some]], which is why the Joes (and later their allies, the Autobots) don't trust him after they liberate him from Cobra, even after [[spoiler: he shoots Buzzer in the head]]. He doesn't exactly give them much reason to trust him, either.

* Zorglub, from ComicBook/SpirouAndFantasio, is one. Champignac is often seen as one by the villagers, and he actually ''behaves'' like one on occasion.
* D.A. Sinclair of ''ComicBook/{{Invincible}}'' is easily one of the most sadistic mad scientists in fiction. He started making zombielike techno-organic minions, Re-Animen, from dead bodies, which is bad enough. But he eventually moved on to ''live'' subjects, kidnapping his roommate and ''tearing out his vocal cords'' so that he couldn't scream while he operated on him (D.A. is a college student, after all, and can't afford anesthetic). And he tore his arm off and overrode his free will. Then he started duplicating the process on homeless people. Naturally, the US Government saw to it that he served no jail time when he was caught, and gave him a cushy job making Re-Animen for military use.
* Simon von Simon from ''ComicBook/LittleGloomy''. He's got it all, from his powerful machinery, futuristic inventions (such as the television and the microwave. Before you say anything, he invented them before anyone else did), hunchbacked HalfheartedHenchman, to his seething rage for everybody but himself. The fact that his plans for world domination were motivated by Gloomy dumping him, and the fact that the series calls him on not marketing his fantastic creations to get on top in a less freaky way undermines his menace somewhat; This, in turn, is offset by his army of ravenous zombies.
%%* Dr Scyk from the Danish comic-strip "Dr Merling".

%%* Voronov in "La Machination Voronov". Who also ends up being something of a KarmaHoudini.
* In ''ComicBook/YTheLastMan'' geneticist Dr Allison Mann claims she was illegally cloning a nephew who needed a bone transplant. She later admits this story was fictional to gain Agent 355's sympathy rather than be thought of as a 'mad scientist'; her actual motive was to spite her father who was nearing success in cloning the first human. [[spoiler: After several red herrings we discover the REAL mad scientist is in fact Allison's father, who was seeking to clone his daughter so he could be a better parent the next time round, yet who also sabotaged Allison's cloning experiment out of sheer spite and may have accidentally caused the plague that all but wiped out all males.]]
%% * ''Franchise/SonicTheHedgehog'':
%% ** In addition to [[BigBad Dr. Robotnik/Eggman]], ''ComicBook/SonicTheHedgehogArchieComics'' has Dr. Finitevus and Dimitri, both of whom work for the Dark Legion, a group who believe in self-augmentation with technology.
%% ** Dr. Zachary from ''ComicBook/SonicTheComic''.
%% ** ''ComicBook/SonicTheHedgehogIDW'' has, in addition to Eggman, Dr. Starline, a fan of Eggman's who is just as brilliant and devious.
%%* Barry Ween, the 10-year-old with a 4-digit IQ in the eponymous series ''ComicBook/TheAdventuresOfBarryWeenBoyGenius''. A representative quote: "Hey -- put that down! That's the controls to my weather satellite! You just flooded Norway!" [short pause] "Well... it's only Norway..."
* There is a double subversion in ''ComicBook/UniversalWarOne''. [[spoiler:The scientist who invented the wormhole is the only one to care about a possible TimeParadox, so he kills the fools who want to "go home" even if it endangers the universe. However, when Kalish explains to him there is no way to create a time paradox, the scientist becomes mad.]]
* Dr. Billy Joe Robidoux from ''ComicBook/WynonnaEarp''. To quote Wynonna: "He's a southern-fried gumbo of Dr. Josef Mengele, Dr. Frankenstein and runs a real-life version of ''Literature/TheIslandOfDoctorMoreau''."
* The Military Doctor in ''ComicBook/{{Sturmtruppen}}'': He believes he's discovered the Invisibility Elixir without getting insane, while his attendants point out that's actually the other way around. He also thought that a case of anemia was actually caused by a Vampire.
* Creator/WarrenEllis's ''ComicBook/DoktorSleepless'' intentionally invokes this: nobody listens to "real people," so he becomes the cartoony mad scientist character of Doktor Sleepless to draw attention.

* Rhona Burchill from ''ComicBook/UltimateFantasticFour''. She was rejected from the Program despite having the natural talents as a scientist, implicitly due to failing the psychiatric evaluation -- since she went on to cut her brother's brain out and graft it to her own, justifiably so. As for what makes her mad... did you just read the previous sentence?

* Profesor Bacterio from ''ComicBook/MortadeloYFilemon''. Both T.I.A. agents have ''very good'' reasons to run away really fast when ordered to test one of his inventions.

* Grant [=McKay=] from ''ComicBook/BlackScience'' is a genius physicist, but his expression of it is tied to his [[TheParanoiac paranoid rejection of all authority figures]] and [[ItsAllAboutMe insanely overblown ego]]. While exploring his mind Doxta specifically asks whether his madness caused or held back his genius. Apparently it runs in the family; Grant's similarly genius father was mentally ill and ended up [[DrivenToSuicide committing suicide]] when Grant was young.
* In ''ComicBook/RainbowBrite'' Murky Dismal has been reimagined as this.
%%* The Russian atomic bomb researcher from ''ComicBook/AtomicRobo''.
* Skunky from ''ComicBook/BunnyVsMonkey'' has built a number of machines for his numerous plans to take over the forest.
* The scientists that captured N°73 in ''ComicBook/BlackTears'' have kidnapped countless children (if our protagonist number means anything, almost a hundred) and turned them all into monsters, all with the purpose of creating what they fear more: [[EldritchAbomination the darkness]]. They are stereotypical one-note madmen, with them having spiral glasses, not different from [[WebVideo/TheSpoonyExperiment Dr.Insano]], and we don't know how or why they got funded for their research, or why they even decided to give a body to an entity they fear.

* In ''ComicBook/SherlockHolmesAndTheHorrorOfFrankenstein'', Dr. Pretorious is the mad scientist who freed the Frankenstein Monster from the Arctic ice, revived it, and is now attempting to create a similar creature.